Heterociclos con nitrógeno (N)

Please enquire for more information about 1-Ethyl-1,4-diazepane including the price, delivery time and more detailed product information at the technical inquiry form on this page

6-Ethyl-5-iodopyriMidine-2,4-diaMine is a structural analog of pyrimethamine. It has been shown to be an antimalarial drug that acts as a competitive inhibitor of the enzyme dihydrofolate reductase (DHFR), which is required for the synthesis of tetrahydrofolate. This drug also inhibits the activity of other enzymes in the folate pathway, such as thymidylate synthase and glycinamide ribonucleotide formyltransferase. 6-Ethyl-5-iodopyriMidine-2,4-diaMine has been shown to inhibit DNA synthesis in human erythrocytes and to inhibit bacterial growth when used at high doses.

Applications 3-aminoisoxazole-4-carbonitrile (cas# 258518-65-9) is a useful research chemical.

Applications An intermediate in the synthesis of rabeprazole (R070500).

Please enquire for more information about 2-Bromo-3-methylpyridine-5-boronic acid, pinacol ester including the price, delivery time and more detailed product information at the technical inquiry form on this page

Applications Can be used in the preparation of substances for treatment of dermatological conditions and skin protection.

Applications 5-Chloro-6-(2,3-dichlorophenoxy)-1,3-dihydro-2H-Benzimidazole-2-thione is used in the preparation of triclabendazoles which are drugs used to treat liver fluke. References Iddon, B., et al.:Journal of the Chemical Society 22, 3129 (1992);

N-(1-Oxyl-2,2,6,6-tetramethyl-4-piperidinyl)maleimide (TTFA) is a reactive molecule that belongs to the class of maleimides. TTFA has been shown to be stable in physiological levels and is not toxic at low concentrations. TTFA binds to serine protease enzymes and inhibits their activity. This inhibition can be used as a model for the inhibition of influenza virus replication by serine proteases. TTFA inhibits translation in a variety of model systems, including yeast, bacteria and mammalian cells. TTFA also inhibits mitochondrial protein synthesis in a model system with rat liver mitochondria and human leukemia cells. In addition, TTFA inhibits fatty acid biosynthesis in yeast cells. The reactivity of this molecule makes it useful for studying the dynamics of protein folding under physiological conditions.

5-Pyridin-2-yl-1,3,4-oxadiazole-2-thiol is a synthetic compound that has been shown to have anticancer properties in vitro. It inhibits the mitochondrial electron transport chain by binding to the mitochondrial membrane and inhibiting the enzyme cytochrome c oxidase. This leads to an accumulation of reactive oxygen species and induction of apoptosis in cancer cells. 5-Pyridin-2-yl-1,3,4-oxadiazole-2-thiol also inhibits luminescence properties of picolinic acid with anions. The primary function of this compound is to inhibit cancer cell growth by causing them to undergo apoptosis. 5PYRODS also binds to mitochondria and blocks the electron transport chain. This leads to an accumulation of reactive oxygen species (ROS) and the induction of apoptosis in cancer cells. 5PYRODS also inhibits luminescence properties of picolin

6-Bromopyridine-3,4-diamine is a chemical compound that can be used to make other products. It can be synthesized by reacting phosphorus with brominating agents such as stannous chloride or chlorine. This reaction produces 6-bromopyridine-3,4-diamine and the target product, which is a methanol solution of stannous chloride peroxide. The chemical is used in the production of many different products, including plastics, dyes, and pharmaceuticals.