Antimicrobianos

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Tuberculosis inhibitor 3 is a synthesized chemical compound designed to target the Mycobacterium tuberculosis bacterium, which is the causative agent of tuberculosis. This inhibitor is derived through advanced chemical synthesis techniques, involving the modification of specific molecular structures to enhance its binding affinity and specificity toward the bacterial cellular targets. The mode of action of Tuberculosis inhibitor 3 involves disrupting essential biochemical pathways within the bacterium. It specifically binds to a critical enzyme or protein involved in the bacteria's metabolic process necessary for survival and replication. By inhibiting this key pathway, the compound effectively reduces bacterial growth and proliferation, contributing to its potential as a therapeutic agent. The primary application of Tuberculosis inhibitor 3 lies in its use as a research tool for studying the molecular biology of Mycobacterium tuberculosis. It serves as a valuable component in the development of new therapeutic strategies and drug discovery processes aimed at controlling or eradicating tuberculosis. Furthermore, its use in laboratory settings can help elucidate the mechanisms of drug resistance and guide the design of novel compounds with enhanced efficacy against resistant strains of tuberculosis.

Neoaureothin is a natural antibiotic product, which is derived from marine actinomycetes with a complex polyketide structure. Its mode of action involves the inhibition of bacterial protein synthesis by binding selectively to the ribosomal subunits, thereby obstructing the translation process in susceptible microbial strains. The specificity of its action allows it to target a broad spectrum of Gram-positive bacteria while presenting a lower risk of resistance development compared to traditional antibiotics. Neoaureothin is utilized extensively in research settings to explore novel antibacterial pathways and potential therapeutic applications in combating resistant bacterial strains. Its unique source and mode of action make it a valuable tool in the study of marine-derived antibiotics, offering insights into alternative treatment strategies for bacterial infections. Researchers often employ this compound in experimental assays to gauge inhibition potency, elucidate biological pathways, and refine synthetic analogues for enhanced efficacy.

Membrane pore-forming agent; H+, K+, Pb2+ ionophore; polyether antibiotic

Tenofovir disoproxil is a nucleotide analog reverse transcriptase inhibitor that is used to treat infections such as Hepatitis-B and HIV. This drug is an antiretroviral agent that blocks reverse transcriptase, blocking viral replication. Tenofovir disoproxil fumarate is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready-to-use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.

Gatifloxacin related compound E is a chemical reference standard, which is often used in pharmaceutical and analytical chemistry research for the identification and quantification of impurities. It is generally synthesized or isolated as part of the quality control and validation process for the production of the antibiotic Gatifloxacin. The mode of action of this compound revolves around its structural similarity to Gatifloxacin, which allows it to serve as a benchmark to ensure the accuracy and reliability of high-performance liquid chromatography (HPLC) and other analytical techniques. In scientific applications, Gatifloxacin related compound E is employed to evaluate the purity of Gatifloxacin formulations by detecting and quantifying potential impurities that could affect the efficacy and safety of the pharmaceutical product. It is crucial in the quality assurance of drug manufacturing processes, contributing to the integrity of the final pharmaceutical product by confirming that impurity levels are within acceptable ranges established by regulatory guidelines.

Applications Labelled Ascorbic Acid. Physiological antioxidant. Coenzyme for a number of hydroxylation reactions; required for collagen synthesis. Widely distributed in plants and animals. Inadequate intake results in deficiency syndromes such as scurvy. Used as antimicrobial and antioxidant in foodstuffs. References Al-Meshal, I.A., et al.: Anal. Profiles Drug Subs., 11, 45 (1982), Levine, M., et al.: N. Engl. J. Med., 314, 892 (1986), Prust, C., et al.: Nature Biotech., 23, 195 (2005),

Quinofumelin is a fungicide, which is synthetically derived with a novel mode of action targeting specific biochemical pathways in fungi. Its unique mechanism disrupts crucial cellular processes within pathogenic fungi, thereby halting their growth and spread. This fungicide has been meticulously developed through advanced chemical synthesis to ensure high efficacy and specificity against a broad spectrum of fungal pathogens affecting various crops. The primary application of Quinofumelin is in the agricultural sector, where it plays a pivotal role in protecting crops from diseases that can compromise yield and quality. It is particularly effective against fungal diseases in cereals, fruits, and vegetables, providing a reliable solution for managing diseases such as powdery mildew, rusts, and blights. By integrating Quinofumelin into crop protection programs, researchers and agricultural professionals can enhance resistance management strategies, thereby supporting sustainable agricultural practices. Its deployment not only secures crop health but also contributes to food security by ensuring consistent and healthy yields.

Inhibitor of protein synthesis; lincosamide

Lumefantrine is an antimalarial compound with action on erythrocytic stages of Plasmodium falciparum by inhibiting β-hematin formation and is used for treating malaria in combination with artemether.

Radicinol is a natural compound, which is a dihydroflavonol primarily sourced from plant origins. This compound is biosynthesized in specific plant species and extracted through meticulous biochemical processes to ensure its purity and efficacy. The mode of action of Radicinol involves the modulation of specific cellular pathways, conferring antioxidative and anti-inflammatory properties. It acts by scavenging free radicals and enhancing cellular resilience against oxidative stress. Radicinol's applications are predominantly in research settings, where its antioxidative properties are of particular interest. Scientists investigate its potential in modulating cellular responses, exploring its influence on metabolic pathways, and targeting oxidative stress-related conditions. The compound shows promise in experimental models of inflammation and cellular aging, making it a valuable subject of study in the fields of biochemistry and molecular biology.

This product is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready-to-use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.

Coronarin D ethyl ether is a diterpenoid compound, which is derived from the plant Hedychium coronarium, also known as white ginger lily. This compound belongs to a class of naturally occurring chemicals with complex polycyclic structures. The source of Coronarin D ethyl ether is the rhizome of Hedychium coronarium, which is part of the Zingiberaceae family. These plants are often studied for their bioactive properties and potential therapeutic applications. The mode of action of Coronarin D ethyl ether involves the induction of apoptosis in cancerous cells. It achieves this through the modulation of cellular signaling pathways that are crucial for cell survival and proliferation. Specifically, it is known to interfere with the NF-κB signaling pathway, which is often implicated in cancer progression and inflammation. By inhibiting this pathway, Coronarin D ethyl ether can promote the apoptotic death of malignant cells. The primary applications of Coronarin D ethyl ether are in the realm of cancer research, where it is being explored for its therapeutic potential as an anticancer agent. Additionally, it is used in preclinical studies to better understand its mechanistic pathways and efficacy in various cancer models. Its ability to selectively target cancer cells while minimizing damage to normal cells makes it a compound of considerable interest in oncology research.

Macranthoside B is a natural iridoid glycoside, which is derived primarily from the roots of certain plants, such as Rehmannia species. This compound is known for its biological activity, which includes potential anti-inflammatory and antioxidant effects. The mode of action of macranthoside B involves modulation of various cellular pathways, possibly through the inhibition of inflammatory mediators and free radical scavenging. Macranthoside B is used extensively in scientific research to explore its pharmacological potential. Researchers investigate its applications in treating inflammatory diseases, oxidative stress-related conditions, and other health disorders. The compound's ability to influence cellular mechanisms makes it a subject of interest in the development of new therapeutic agents. Its role in modulating physiological responses underlines its potential utility in drug discovery and development.

Tobramycin is used to treat severe infections with gram-negative bacteria and it is often applied in combination with beta-lactams. It has similar antimicrobial effects to gentamicin and is effective against all Enterobacteriacae, but more effective than gentamicin against P. aeruginosa, which is why it is often used for gentamicin-resistant strains, especially in the case of cystic fibrosis.

Applications Methyl trans-Cinnamate is one of the odour active compounds of Tahitian vanilla flavour and basil oil. Methyl trans-Cinnamate is naturally found in Magnolia liliflora oil, which is used to create a variety of nematicides. Methyl trans-Cinnamate also inhibits mushroom tyrosinase and has antimicrobial effects against Escherechia coli in food. References Adams, A., et al.: J. Am. Oil Chem. Soc., 88, 201 (2011); Blank, A., et al.: Ind. Crop. Prod., 38, 93 (2012); Brunschwig, C., et al.: Food Res. Int., 46, 148 (2012); Huang, Q., et al.: J. Agr. Food Chem., 57, 2565 (2009)