Hormonas
Las hormonas son mensajeros bioquímicos producidos por las glándulas en organismos multicelulares que regulan procesos fisiológicos y comportamientos. Estas moléculas de señalización son esenciales para mantener la homeostasis, el crecimiento, el metabolismo y la reproducción. En esta categoría, encontrará una selección completa de hormonas disponibles para fines de investigación, incluyendo esteroides, péptidos y aminas. Estos productos son cruciales para estudiar las funciones endocrinas, desarrollar tratamientos terapéuticos y avanzar en nuestra comprensión de la regulación hormonal en la salud y la enfermedad. En CymitQuimica, proporcionamos hormonas de alta calidad para apoyar sus necesidades de investigación en bioquímica, farmacología y ciencias médicas.
Productos de "Hormonas"
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Icomethasone 21-Mesylate
CAS:Producto controladoImpurity Mometasone Furoate Impurity N / Mometasone EP Impurity N Applications Icomethasone 21-Mesylate is a derivative of Icomethasone (I164100), used in the preparation of Mometasone (M489995).Fórmula:C23H31ClO7SForma y color:Off WhitePeso molecular:487.016beta-Hydroxy Dutasteride
Applications 6β-Hydroxy Dutasteride is a hydroxylated derivative of Dutasteride (D735000).Fórmula:C27H30F6N2O3Forma y color:NeatPeso molecular:544.431,2-Dihydro Dexamethasone Phosphate Disodium Salt
Stability Hygroscopic Applications 1,2-Dihydro Dexamethasone Phosphate Disodium Salt is an impurity of Dexamethasone Phosphate (D298835). References Kodelja, V., et al.: J. Immunol., 160, 1411 (1998), Metselaar, J., et al.: Arthritis Rheum., 48, 2059 (2003), Buttgereit, F., et al.: Arthritis Rheum., 50, 3408 (2004), Martinez, F., et al.: Front Biosci., 13, 453 (2008),Fórmula:C22H30FNa2O8PForma y color:NeatPeso molecular:518.4211β,17α,21-Trihydroxypregn-4-ene-3,20-dione
CAS:Fórmula:C21H30O5Pureza:98%Forma y color:SolidPeso molecular:362.45994-Hydroxy Estradiol 1-N7-Guanine
CAS:Producto controladoApplications 4-Hydroxy Estradiol 1-N7-Guanine is an estrogen metabolite formed with DNA which can lead to the mutations that initiate breast, prostate, and other types of cancer. Estrogen-DNA depurinating adducts as biomarkers of cancer risk and their use in cancer detection and prevention. References Chakravarti, D., et al.: Mutat. Res., 456, 17 (2000), Liehr, J., et al.: Endocr. Rev., 21, 4054 (2000), Chakravarti, D., et al.: Oncogene, 20, 7945 (2001), Cavalieri, E., et al.: Chem. Res. Toxicol., 14, 1041 (2002),Fórmula:C23H27N5O4Forma y color:NeatPeso molecular:437.49(3alpha,17alpha)-4-Chloro-3-hydroxy-17-methyl-18-Norandrosta-4,13-diene-17-methanol
CAS:Producto controladoApplications (3α,17α)-4-Chloro-3-hydroxy-17-methyl-18-Norandrosta-4,13-diene-17-methanol is a metabolite of Dehydrochloromethyltestosterone (DHCMT) and a related compound of clostebol acetate (C587395), an anabolic steroid. References Roy, D., et al.: Eur. J. Med. Chem., 42, 1365 (2007); Alvarez-Ginarte, Y., et al.: Bioorg. Med. Chem., 16, 6448 (2008); Srivastava, H., et al.: Med. Chem. Res., 18, 455 (2009)Fórmula:C20H29ClO2Forma y color:NeatPeso molecular:336.9Tixocortol 21-Pivalate
CAS:Producto controladoApplications Tixocortol 21-Pivalate is an anti-inflammatory agent. Tixocortol 21-Pivalate is used in fluorescent chemoaffinity labeling. References Torossian, D.R., et al.: Arzneim.-Forsch., 31, 453 (1981),Fórmula:C26H38O5SForma y color:NeatPeso molecular:462.64Dimethazine
CAS:Producto controladoApplications Diamethazine is an C17-alkylated, anabolic-androgenic steroid, that exhibits similar effects to Superdrol (M226010). References Orlandi, F., et al.: Adv. Hepatol. Trans. Int. Symp. Int. Assoc. Study Liver., 109 (1965); Shakoori, A. R, et al.: Proceeding. Congress. Zool., 24, 1 (2004);Fórmula:C42H68N2O2Forma y color:NeatPeso molecular:633.00Lysipressin-d5 Trifluoroacetic Acid Salt
CAS:Producto controladoStability Hygroscopic Applications Isotope labelled Lysipressin (L488770) is an analog of Vasopressin (A769550), a powerful vasopressor used to modulate blood pressure. An endogenous antidiuretic hormone in most mammalian species. It is released into the blood from nerve terminals in the posterior pituitary and median eminence. It is a neurotransmitter in the central nervous system and also implicated in a variety of physiological processes such as regulating water balance by antidiuretic action. References Perucca, J. et al.: J. AM. Soc. Nephrol., 19, 1721 (2008); Toba, K. et al.: Prog. Brain Res., 119, 337 (1998); Berrada, K. et al.: J. Biol. Chem., 275, 27229 (2000);Fórmula:C46H60D5N13O12S2•x(C2HF3O2)Forma y color:NeatPeso molecular:1061.2511402Triptorelin Acetate
CAS:Producto controladoStability Hygroscopic Applications Synthetic peptide agonist analog of LH-RH. Triptoreline is a potent agonist of LH-releasing hormone, currently used in the treatment of prostatic cancer where therapy may be required over months or years. Antineoplastic (hormonal). Used in the treatment of endometriosis and infertility. References Sanders, L., et al.: Eur. J. Drug Metab. Pharmacokinet., 15, 95 (1990), Chiba, M., et al.: Biomaterials, 18, 893 (1997), Blanco, D., et al.: Eur. J. Pharm. Biopharm., 45, 285 (1998), Sinha, V., et al.: J. Control. Rel., 90, 261 (2003),Fórmula:C64H82N18O13·xC2H4O2Forma y color:NeatPeso molecular:1371.50Dydrogesterone-d6 (Major)
CAS:Producto controladoApplications Labelled Dydrogesterone. A synthetic progestin largely used in hormone therapy, on the central nervous system by studying two markers of the neuroendocrine function: the neurosteroid allopregnanolone and the opioid .beta.-endorphin. Progestogen. References Bernardi, F., et al.: Eur. J. Endocrinol., 138, 316 (1998), Rupprecht, R., et al.: Steroids, 64, 83 (1999), Uzunova, V., et al.: Brain Res., 976, 1 (2003), Pluchino, N., et al.: J. Steroid Biochem. Mol. Biol., 102, 205 (2006),Fórmula:C21H22D6O2Forma y color:NeatPeso molecular:318.48Progesterone extrapure, 97-103%
CAS:Fórmula:C21H30O2Pureza:min. 97%Forma y color:White to off-white, Crystalline powderPeso molecular:314.46Chorionic Gonadotropin/CGA Protein, Human, Recombinant (His)
Chorionic Gonadotropin/CGA Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.Forma y color:Lyophilized PowderPeso molecular:11.6 kDa (predicted); 25.9 kDa (reducing conditions)Delta6-Gestodene
Producto controladoApplications Δ6-Gestodene, is an impurity of Gestodene (G368250), an orally active gestogen with progesterone-like profile of activity. Used in combination with estrogen as oral contraceptive. References Duesterberg, B., et al.: Contraception, 24, 673 (1981); Duesterberg, B., et al.: Seroids, 43, 43 (1984); Losert, W., et al.: Arzneim.-Forsch., 35, 459 (1985);Fórmula:C21H24O2Forma y color:NeatPeso molecular:308.414-Hydroxy Estrone-d4
CAS:Producto controladoApplications A labelled metabolite of Estradiol. References Fishman, H.G, et al.: Biochemistry, 8, 4304 (1969), Ryan, Sugar, J., et al.: J. Clin. Endocrinol. Metab., 50, 137 (1980), Numazawa, M., et al.: Steroids, 38, 149 (1981), Travis, R., et al.: Breast Cancer Res., 5, 239 (2003),Fórmula:C182H4H18O3Forma y color:NeatPeso molecular:290.39Clobetasol 17-Propionate-d5
CAS:Producto controladoApplications Clobetasol 17-Propionate-d5 is labelled Clobetasol 17-Propionate (C583500) which is a topical corticosteroid. Clobetasol 17-Propionate (C583500) is anti-inflammatory. References Olsen, E.A., et al.: J. Am. Acad. Dermatol., 15, 246 (1986),Fórmula:C25H27D5ClFO5Forma y color:NeatPeso molecular:472.02,2’-[5-(1H-1,2,4-Triazol-1-yl)methylbenzene-1,3-diyl]bis(2-methylpropanamide)
CAS:Forma y color:NeatBis-(6Alpha-Methylprednisolone) 21,21’-Ether
Producto controladoFórmula:C44H58O9Forma y color:NeatPeso molecular:730.94Methyl Lithocholate
CAS:Producto controladoApplications Methyl Lithocholate is an derivative of Lithocholic Acid (L469180),a cholic acid derivative as TGR5 modulator. Found in ox bile, human bile, rabbit bile, and in ox and pig gallstones. References Roleira, F.M., et al.: Lett. Drug. Design. Discovery., 7, 610 (2010);Fórmula:C25H42O3Forma y color:NeatPeso molecular:390.603,3’,5-Triiodo-L-thyronine-13C6
CAS:Applications One of the hormones produced by the thyroid gland that is involved in the maintenance of metabolic homeostasis. Also produced in peripheral tissues as the active metabolite of Thyroxine. References Gross, J., et al.: Lancet I, 439 (1952), Roche, J., et al.: Biochim. Biophys. Acta, 11, 215 (1953), Chacon, M.A., et al.: J. Pediatr., 99, 758 (1981), Chopra, I.J., et al.: Thyroid, 6, 255 (1996),Fórmula:C6C9H12I3NO4Forma y color:Beige To BrownPeso molecular:656.9321-Chloro-9,11β-epoxy-16α-methyl-3,20-dioxo-9β-pregna-1,4-dien-17-yl Furan-2-carboxylate
CAS:Fórmula:C27H29ClO6Glycodeoxycholic Acid-3-O-Beta-glucuronide Disodium Salt
CAS:Producto controladoFórmula:C32H49NNa2O11Forma y color:NeatPeso molecular:669.7117Beta-Estradiol-13C2
CAS:Producto controladoApplications Isotope labelled 17β-Estradiol (E888000), which is the major estrogen (1) secreted by the premenopausal ovary (2).Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA), environmental, and food contaminants. References 1. Salole, E. et al.: Anal. Profiles Drug Subs. 1986 15, 23 283-3182. Lievertz, R. et al.: Am. J. Obstet. Gynecol. 1987 May;156(5):1289-93.Fórmula:C2C16H24O2Forma y color:WhitePeso molecular:274.37Beclomethasone-d5
CAS:Producto controladoApplications Glucocorticoid. Used in chronic asthma and allergic rhinitis. Antiallergic, antiasthmatic (inhalant). Anti-inflammatory (topical). References Malfitan, V.A., et al.: Clin. Ther., 4, 472 (1982), Rao, M., et al.: J. Asthma, 19, 21 (1982), Small, P., et al.: Ann. Allergy, 49, 127 (1982), Brogden, R.N., et al.: Drugs, 28, 99 (1984),Fórmula:C22H24D5ClO5Forma y color:NeatPeso molecular:413.95Finasteride 2-(2-Methylpropanol)amide
CAS:Producto controladoFórmula:C23H36N2O3Forma y color:NeatPeso molecular:388.54Tauro-b-muricholic Acid-d4 Sodium Salt
CAS:Producto controladoStability Hygroscopic Applications Sodium salt of Tauro-α-muricholic Acid is a labeled bile acid released by the liver and is typically used in cholestasis studies. References Yang, L. et al.: Chem. Res. Toxicol., 21, 2280 (2008); Holm, R. et al.: Phys. Chem. Chem. Phys., 11, 5070 (2009);Fórmula:C26H40D4NNaO7SForma y color:White To Off-WhitePeso molecular:541.716Beta-Hydroxy Budesonide-d8
CAS:Producto controladoApplications A labelled metabolite of Budesonide (B689490), a non-halogenated glucocorticoid related to triamcinolone hexacetonide. Used as an antiinflammatory agent. References Ryrfeldt., A., et a.: J. Steroid Biochem., 10, 317 (1979), Roth, G., et al.: J. Pharm. Sci., 69, 766 (1980), Edsbaecker, S., et al.: Drug Metab. Dispos., 15, 412 (1987),Fórmula:C25H26D8O7Pureza:~90%Forma y color:NeatPeso molecular:454.58Prednisolone phosphate sodium
CAS:Fórmula:C21H27Na2O8PPureza:97%Forma y color:SolidPeso molecular:484.38764-Pregnen-6α-methyl-17-ol-3,20-dione-2,2,4,6,21,21,21-d7 17-Acetate
CAS:Producto controladoFórmula:C24H27D7O4Forma y color:NeatPeso molecular:393.57Methyl 4-(2-Hydroxyethoxy)benzoate
CAS:Producto controladoFórmula:C10H12O4Forma y color:NeatPeso molecular:196.206Beta,17Alpha-Dihydroxyprogesterone
CAS:Producto controladoFórmula:C21H30O4Forma y color:NeatPeso molecular:346.46Serricornin (Mixture of Isomers)
CAS:Producto controladoApplications The sex pheromone of Cigarette Beetle.Fórmula:C11H22O2Forma y color:NeatPeso molecular:186.29Nandrolone Cypionate
CAS:Producto controladoApplications Nandrolone Cypionate is a metabolite of nandrolone (N315000) which is an anabolic steroid. References Gradeen, C., et al.: J. Anal. Toxicol., 14, 120 (1990), Teale, P., et al.: Biol. Mass Spectrom., 20, 109 (1991), Yamada, M., et al.: J. Pharm. Biomed. Anal., 45, 125 (2007), Yamada, M., et al.: J. Anal. Toxicol., 32, 387 (2008),Fórmula:C26H38O3Forma y color:Off White SolidPeso molecular:398.58Megestrol Acetate-d3
CAS:Producto controladoApplications Orally active progestogen; formerly used in combinations as oral contraceptive. References Chang, K., et al.: Steroids 12, 689 (1968),Fórmula:C242H3H29O4Forma y color:White To Light YellowPeso molecular:387.53Erythroferrone Protein, Mouse, Recombinant (His)
Iron-regulatory hormone that acts as an erythroid regulator after hemorrhage: produced by erythroblasts following blood loss and mediates suppression ofPureza:SDS-PAGE: > 90%Forma y color:Lyophilized PowderPeso molecular:35.9 kDa (predicted)5,6-Dehydro-17Beta-dutasteride
CAS:Producto controladoImpurity Dutateride EP Impurity G Applications 5,6-Dehydro-dutasteride (Dutateride EP Impurity G) is an impurity in the synthesis of Dutasteride (D735000), a dual inhibitor of 5α-reductase isoenzymes type 1 and 2; structurally related to Finasteride (F342000). Dutasteride is used in the treatment of benign prostatic hyperplasia. References Bakshi, R.K., et al.: J. Med. Chem., 38, 3189 (1995), Gisleskog, P.O., et al.: Brit. J. Clin. Pharmacol., 47, 53 (1999), Djavan, B., et al.: Expert Opin. Pharmacother., 6, 311 (2005),Fórmula:C27H28F6N2O2Forma y color:NeatPeso molecular:526.5117Alpha-Trenbolone-d3
CAS:Producto controladoApplications 17α-Trenbolone-d3 is the labeled 17α-Trenbolone (T718990) which is a controlled substance (anabolic steroid) and a prohormone of Trenbolone (T719000). References Schanzer, W., et al.: Clin. Chem., 42, 1001 (1996), Kicman, A., et al.: Br. J. Pharmacol., 154, 502 (2008), Fragkaki, A., et al.: Steroids, 74, 172 (2009),Fórmula:C182H3H19O2Forma y color:Light YellowPeso molecular:273.389-Chloro Triamcinolone Acetonide
CAS:Applications Triamcinolone Acetonide (T767165) impurity. References Laurent, H., et al.: J. Steroid Biochem., 6, 185 (1975),Fórmula:C24H31ClO6Forma y color:WhitePeso molecular:450.95Resistin Protein, Human, Recombinant (His)
Resistin known as adipose tissue-specific secretory factor (ADSF) or C/EBP-epsilon-regulated myeloid-specific secreted cysteine-rich protein (XCP1) that seemsForma y color:Lyophilized PowderPeso molecular:10—14 KDa (reducing condition)Cyproterone
CAS:Producto controladoImpurity Cyproterone Acetate EP Impurity F Applications Cyproterone (Cyproterone Acetate EP Impurity F) is an antiandrogen, suppresses Testosterone and its metabolites. Derivatives of Cyproterone are administered to patients suffering from hypersexuality and to help facilitate the sexual transformation of male-to-female transsexuals. References Gracia, T., et al.: Toxicol. App. Pharmacol., 225, 142 (2007), Ahlin, G., et al.: J. Med. Chem., 51, 5932 (2008), Gohil, V., et al.: Nat. Biotechnol., 28, 249 (2010), Bovee, T., et al.: J. Steroid Biochem. Mol. Biol., 118, 85 (2010),Fórmula:C22H27ClO3Forma y color:Off White SolidPeso molecular:374.90Mibolerone
CAS:Producto controladoApplications Synthetic anabolic steroid related to testosterone.Controlled substance (anabolic steroid). References Campbell, J.A., et al.: Steroids, 1, 317 (1963); Hamlin, W.E., et al.: J. Pharm. Sci., 54, 1651 (1965); Sokolowski, J.H., et al.: J. Am. Vet. Med. Assoc., 173, 983 (1978),Fórmula:C20H30O2Forma y color:White SolidPeso molecular:302.455α-Androstane-3α,17β-diol 3-Sulfate Sodium Salt-d3
CAS:Producto controladoApplications 5α-Androstane-3α,17β-diol 3-Sulfate Sodium Salt-d3 is labelled 5α-Androstane-3α,17β-diol Sulfate (A637390, sodium salt), a derivative of 5α-Androstane-3α,17β-diol (A637521) which is a metabolite of Testosterone (T155000). References Kulkarni, S., et al.: Xenobiotica, 35, 955 (2005), Kicman, A., et al.: Br. J. Pharmacol., 154, 502 (2008), Fragkaki, A., et al.: Steroids, 74, 172 (2009),Fórmula:C19H28D3NaO5SForma y color:NeatPeso molecular:397.52Glabridin
CAS:Applications Glabridin is a compound extracted from Licorice (root) shows properties that are cytotoxic, antimicrobial, estrogenic and anti-proliferative. References Tian, M. et al.: Int. J. Mol. Sci., 9, 571 (2008); Simmler, C. et al.: Fitoterapia, 90, 160 (2013);Fórmula:C20H20O4Forma y color:Beige SolidPeso molecular:324.37Gestodene
CAS:Producto controladoApplications Gestodene is an orally active gestogen with a progesterone-like profile of activity. Gestodene is used in combination with estrogen as an oral contraceptive. References Duesterberg, B., et al.: Contraception, 24, 673 (1981), Duesterberg, B., et al.: Seroids, 43, 43 (1984), Losert, W., et al.: Arzneim.-Forsch., 35, 459 (1985),Fórmula:C21H26O2Forma y color:NeatPeso molecular:310.432Beta,3Alpha,5Alpha,16Beta,17Beta)-17-Acetoxy-3-hydroxy-2-(4-morpholinyl)-16-(1-pyrrolidinyl)androstane
CAS:Producto controladoImpurity Rocuronium EP Impurity A Applications (2β,3α,5α,16β,17β)-17-Acetoxy-3-hydroxy-2-(4-morpholinyl)-16-(1-pyrrolidinyl)androstane (Rocuronium EP Impurity A) is a compound is used in the synthesis of the neuromuscular blocking agent rocuronium bromide. References Srinivasan, N. et al.: Orient. J. Chem., 24, 989 (2008);Fórmula:C29H48N2O4Forma y color:NeatPeso molecular:488.70Fluocinolone Acetonide
CAS:Fórmula:C24H30F2O6Pureza:>98.0%(HPLC)Forma y color:White to Almost white powder to crystalPeso molecular:452.49N-Desmethyl Ulipristal Acetate-d3
CAS:Producto controladoApplications N-Desmethyl Ulipristal Acetate-d3, is the labeled analogue of N-Desmethyl Ulipristal Acetate (D296005), which has been shown to contribute significantly to the antiprogestational activity of its parent compound. References Attardi, B.J. et al.: J. Steroid Biochem. Mol. Biol., 88, 277 (2004);Fórmula:C29H32D3NO4Forma y color:Off White PowderPeso molecular:464.61(20S)-Dexamethasone Epimeric Glycolic Acid
CAS:Fórmula:C22H29FO6Forma y color:NeatPeso molecular:408.46FSHB Protein, Mouse, Recombinant (hFc)
Fertility is dependent on follicle-stimulating hormone (FSH), a product of gonadotrope cells of the anterior pituitary gland.Forma y color:Lyophilized PowderPeso molecular:39.2 kDa (predicted). Due to glycosylation, the protein migrates to 50-60 kDa based on Tris-Bis PAGE result.Altrenogest 19,19,20,21,21-d5
CAS:Producto controladoFórmula:C21H21D5O2Forma y color:NeatPeso molecular:315.46Dexamethasone 21-Palmitate-d31
CAS:Producto controladoApplications A labelled orticosteroid prodrug for the treatment of eye disorders. References Benameur, H., et al.: J. Pharm. Pharmacol., 47, 812 (1995), Tauchi, Y., et al.: Biol. Pharm. Bull., 24, 925 (2001), Chono, S., et al.: J. Drug Targeting, 13, 407 (2005),Fórmula:C38D31H28FO6Forma y color:NeatPeso molecular:662.065Alpha-Dihydrolevonorgestrel
CAS:Producto controladoApplications 5α-Dihydrolevonorgestrel is the reduced analogue of levonorgestrel (N689510), a safe, tolerated and effective emergency contraceptive for women. References Cabeza, M., et al.: Steroids., 60, 630 (1995); Lemus, A.E., et al.: J. Steroid. Biochem. Molec. Biol., 41,881 (1992); Bergink. E.W., et al.: J. Steroids. Biochem., 14, 175 (1981);Fórmula:C21H30O2Forma y color:NeatPeso molecular:314.4611-Keto Fusidic Acid
CAS:Impurity Fusidic Acid EP Impurity H Applications 11-Keto Fusidic Acid (Fusidic Acid EP Impurity H) is a metabolite of Fusidic Acid. References Godtfredsen, W.O., et al.: J. Med. Chem., 9, 15 (1966), Perry, M.J., et al.: J. Antibiot., 36, 1659 (1983),Fórmula:C31H46O6Forma y color:Off White SolidPeso molecular:514.69AGRP Protein, Human, Recombinant (hFc)
AGRP Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.Forma y color:Lyophilized PowderPeso molecular:39 kDa (predicted); 39 kDa (reducing conditions)Meteorin-like/METRNL Protein, Rat, Recombinant (His)
Meteorin-like/METRNL Protein, Rat, Recombinant (His) is expressed in E.Forma y color:Lyophilized PowderPeso molecular:33.8 kDa (predicted)Testosterone Sulfate-d3 Triethylamine Salt
CAS:Producto controladoApplications The labelled analogue of a metabolite of Testosterone (T155000). It is a urinary metabolite of Androstenedione (A637550) in patients with Addison's disease and also used as a marker in blood plasma for detection of prostate cancer. References Lokhov, P.G. et al.: Metabolomics, 6, 156 (2010); Bonnaire, Y. et al.: J. Anal. Toxicol., 19, 175 (1995); Tamm, J. et al.: Steroids, 8, 659 (1966);Fórmula:C25H40D3NO5SForma y color:Off-WhitePeso molecular:472.74-Hydroxy Testosterone
CAS:Producto controladoApplications 4-Hydroxytestosterone is an anabolic steroid and does not have any therapeutic indication. 4-Hydroxytestosterone is metabolite of the aromatase inhibitor Formestane (F692250). 4-Hydroxytestosterone concentration in the urine can be used as a biomarker for steroid misuse.Controlled Substance. References Kohler, M. et al.: Steroids, 72, 278 (2007); Brodie, A.M. et al.: J. Steroid. Biochem., 14, 693 (1981); Van Renterghem, P. et al.: Steroids, 75, 154 (2010);Fórmula:C19H28O3Forma y color:NeatPeso molecular:304.426α-Methyl Prednisolone Aceponate
CAS:Applications Used in treatment of seborrhoeic dermatitis includes topical treatments such as corticosteroids, antifungals, metronidazole and pimecrolimus. References Miyachi, Y., et al.: Br. J. Dermatol., 114, 231 (1986), Rallis, E., et al.: Drugs Exp. Clin. Res., 30, 191 (2004), Ozcan, H., et al.: Eur. J. Dermatol., 17, 313 (2007),Fórmula:C27H36O7Forma y color:White To Off-WhitePeso molecular:472.571,2,4,5-Tetrahydrotestolactone
CAS:Producto controladoApplications 1,2,4,5-Tetrahydrotestolactone is a steroid with estrogenic properties. A steroid lactone. References Pollard, I., et al.: Steroids, 11, 897 (1968), Volovel'skii, L. N., et al.: Zh. Obshch. Khim., 43, 1414 (1973)Fórmula:C19H28O3Forma y color:NeatPeso molecular:304.422Calcitonin (salmon) xAcetate
CAS:Producto controladoApplications Calcitonin (salmon), is a 32-amino acid linear polypeptide hormone that is produced in thyroid in humans. It acts to reduce blood calcium (Ca2+), opposing the effects of parathyroid hormone (PTH). References Boron, WF. et al.: Med. Phys., A Cellular and Molecular Approach (2004); Andreotti, G. et al.: J. Bio. Chem., 281, 24193 (2006);Fórmula:C145H240N44O48S2·x(CH3CO2H)Forma y color:NeatPeso molecular:3431.85600521-Dehydro Dexamethasone Hydrate
CAS:Fórmula:C22H27FO5·H2OForma y color:White To Light YellowPeso molecular:408.46(8R,9S,10R,13S,14S)-10,13-Dimethyl-6-methylene-7,8,9,11,12,13,15,16-octahydro-6H-cyclopenta[a]phenanthrene-3,17(10H,14H)-dione
CAS:Fórmula:C20H24O2Pureza:99%Forma y color:SolidPeso molecular:296.4034Norethisterone 100 µg/mL in Acetonitrile
CAS:Fórmula:C20H26O2Forma y color:Single SolutionPeso molecular:298.42Prednisolone 21-Sulfate Sodium Salt
CAS:Producto controladoStability Hygroscopic Applications Prednisolone 21-Sulfate is a metabolite of Prednisolone (P703740). References Hutzler, J., ET AL.: Drug Metab. Dispos., 30, 355 (2002), Sugiyama, D., et al.: J. Biol. Chem., 278, 43489 (2003), Hagenbuch, B., et al.: Xenobiotica, 38, 778 (2008),Fórmula:C21H27NaO8SForma y color:NeatPeso molecular:462.49Medroxy Progesterone-D6 17-Acetate
CAS:Producto controladoApplications Labelled Medroxyprogesterone (M203560). Progestogen; an injectable contraceptive. References Tang, M., et al.: Endocrinol., 151, 1320 (2010), Lee, K., et al.: Mol. Cell. Endocrinol., 319, 109 (2010), Rodgers, A., et al.: Chem., Res. Toxicol., 23, 724 (2010), Gohil, V., et al.: Nat. Biotechnol., 28, 249 (2010),Fórmula:C242H6H28O4Forma y color:NeatPeso molecular:392.56Dexamethasone Phosphate Bisulfate Adduct Sodium Salt
CAS:Fórmula:C22H32FO11PS•xNaForma y color:NeatPeso molecular:554.52229817Alpha-Methyl-5Alpha-androstane-2Beta,3Alpha,17Beta-triol
CAS:Producto controladoApplications 17α-Methyl-5α-androstane-2β,3α,17β)-triol is a derivative of Madol (M108000, which is an anabolic steroid recently identified to be misused as a doping agent. The potency of Madol (DMT) to transactivate androgen receptor (AR) dependent reporter gene expression was two times lower as compared to dihydrotestosterone (DHT). References Zierau, O., et al.: Planta Med., 69, 856 (2003), Takahashi, M., et al.: Endocr. J., 51, 425 (2004), Labrie, F., et al.: J. Endocrinol., 184, 427 (2005),Friedel, A., et al.: Toxicol. Lett., 164, 16(2006),Fórmula:C20H34O3Forma y color:NeatPeso molecular:322.48Glucagon-d9 Trifluoroacetate
CAS:Producto controladoFórmula:C153H216D9N43O49Sx(C2HF3O2)Forma y color:NeatPeso molecular:3491.8GIP Protein, Mouse, Recombinant (His)
The potential application of glucose-dependent insulinotropic polypeptide (gastric inhibitory polypeptide, GIP) in the management of obesity and type 2 diabetesForma y color:Lyophilized PowderPeso molecular:8.7 kDa (predicted). Due to glycosylation, the protein migrates to 13-18 kDa based on Tris-Bis PAGE result.3Beta-Cholic Acid
CAS:Producto controladoApplications Possible Progesterone metabolite. References Meng, L., et al.: J. Hepatol., 27, 346 (1997), Ho, C., et al.: Biochem., 45, 5695 (2006),Fórmula:C24H40O5Forma y color:White To Off-WhitePeso molecular:408.57GHRL Protein, Mouse, Recombinant (His)
Ghrelin is the ligand for growth hormone secretagogue receptor type 1 (GHSR).Forma y color:Lyophilized PowderPeso molecular:14.8 kDa (predicted)Isopregnanolone-d5
CAS:Producto controladoApplications Isopregnanolone-d5 is the isotope labelled analogue of Isopregnanolone (I822200), an derivative used in the preparation of antimicrobial and anti-leukemic steroids. References Shingate, B. et al.: Chem. Biol. Int., 1, 198 (2011); Jegham, H. et al.: Steroids., 77, 1403 (2012);Fórmula:C21H29D5O2Forma y color:White To Off-WhitePeso molecular:323.52Clomiphene citrate
CAS:Producto controladoFórmula:C26H28ClNO·C6H8O7Forma y color:NeatPeso molecular:598.08Methimazole-d3
CAS:Producto controladoStability Air Sensitive Applications Methimazole is a thiourea antithyroid agent that prevents iodine organification, thus inhibiting the synthesis of thyroxine. Antihyperthyroid. References Sitar, D.S., et al.: J. Pharmacol. Exp. Ther., 184, 432 (1973), Aboul-Enein, H.Y., et al.: Anal. Profiles Drug Subs., 8, 351 (1979), Cooper, D.S., et al.: N. Engl. J. Med., 311, 1353 (1984), Atterwill, C.K., et al.: Food Chem. Toxicol., 29, 355 (1991),Fórmula:C4D3H3N2SForma y color:Light BrownPeso molecular:117.19Testosterone-2,2,4,6,6-d5 Acetate
CAS:Producto controladoApplications Testosterone-2,2,4,6,6-d5 Acetate is a useful isotopically labeled compound of Testosterone 17-O-Acetate (T155025)Fórmula:C21H25D5O3Forma y color:NeatPeso molecular:335.5FSH β Protein, Human, Recombinant (His)
FSH Beta Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.Forma y color:Lyophilized PowderPeso molecular:13.9 kDa (predicted)Norethindrone-2,2,4,6,6,10-d6
CAS:Producto controladoApplications Isotope labelled Norethindrone (N676000), a labelled progesterone in combination with acetate used as an oral contraceptive (1,2). It is reasonably anticipated to be a human carcinogen. Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA), environmental, and food contaminants. References 1. Shroff, A. et al.: Anal. Profiles Drug Subst. 1975 ; 4;268-2932. Singh, H. et al.: Am. J .Obstet. Gynecol. 1979 Oct 1;135(3):409-14Fórmula:C20D6H20O2Forma y color:NeatPeso molecular:304.46Tetrahydrodehydrocorticosterone
CAS:Producto controladoApplications Tetrahydrodehydrocorticosterone inhibits aldosteronogenesis by intact cells at concentrations that inhibited angiotensin binding. References Campanile, C.P., Goodfriend, T.L.: Steroids, 37, 681(1981)Fórmula:C21H32O4Forma y color:NeatPeso molecular:348.48(17Beta)-4,17-Dimethyl-androsta-2,4-dieno[2,3-d]isoxazol-17-ol
CAS:Producto controladoApplications Used in the preparation of Epostane (E588850).Fórmula:C22H31NO2Forma y color:NeatPeso molecular:341.49Testosterone 17-Isocaproate
CAS:Producto controladoApplications Testosterone Isocaproate, is one of the common anabolic steroid esters. It is a controlled substance in US due to their potential for abuse and misuse. It can be used for the treatment of constitutional delayed puberty (CDP), in combination of other testosterone esters. References Noggie, F. T., et al.: J. Chromatography. Sci., 28 (5), 263 (1990); Buyukgebiz, A., et al.: Hormone REs., 44 Suppl 3, 32 (1995);Fórmula:C25H38O3Forma y color:White To Off-WhitePeso molecular:386.573-10-Caerulein, 5-L-methionine-
CAS:Fórmula:C49H62N10O16S3Pureza:97%Forma y color:SolidPeso molecular:1143.269Adiponectin Protein, Bovine, Recombinant (His)
Adiponectin Protein, Bovine, Recombinant (His) is expressed in yeast with N-6xHis tag.Forma y color:Lyophilized PowderPeso molecular:26.4 kDa (predicted)Ethynyl Estradiol 3-Sulfate Sodium Salt (>85%)
CAS:Fórmula:C20H23NaO5SPureza:>85%Forma y color:White To Light OrangePeso molecular:398.455beta-Finasteride
CAS:Producto controladoApplications 5β-Finasteride is an azasteroid and 5β-isomeric impurity of Finasteride (F342000). References Cendrowska, I. et al.: J. Liq. Chrom. Rel. Technol., 22, 2259 (1999);Fórmula:C23H36N2O2Forma y color:Off-WhitePeso molecular:372.54Melatonin-d4
CAS:Producto controladoApplications Hormone; mediates photoperiodicity in mammals; inhibits cerebellar nitric oxide synthetase; peroxynitrite scavenger. Melatonin has complex effects on apoptotic pathways, inhibiting apoptosis in immune cells and neurons but enhancing apoptotic cell death of cancer cells. Inhibits proliferation/metastasis of breast cancer cells by inhibiting estrogen receptor action. References Barchas, et al.: Nature, 214, 919 (1967), Glass, J.D., et al.: Science, 214, 821 (1981),Fórmula:C132H4H12N2O2Forma y color:Off-White To BeigePeso molecular:236.30Pregnenolone-d4
CAS:Producto controladoApplications Pregnenolone-d4, is the labeled analogue of the Pregnenolone (P712200), which is a steroid hormone involved in the steroidogenesis of progesterone, mineralocorticoids, glucocorticoids, androgens, and estrogens. References Bjondahl, K., et al.: Med. Biol., 54, 454 (1976), Geick, A., et al.: J. Biol. Chem., 276, 14581 (2001), Johnson, D., et al.: Toxicol. Sci., 66, 16 (2002), Abe, C., et al.: Lipids, 42, 637 (2007),Fórmula:C212H4H28O2Forma y color:Off-WhitePeso molecular:320.50Oleanolic Acid-d3
CAS:Producto controladoApplications Oleanolic Acid-d3, is the labeled analogue of Oleanolic Acid (O521000), which is a triterpenoid known for its anti-inflammatory properties, is commonly present in several medicinal plants. It also inhibits secretory phospholipase A2. References Andrikopoulos, N., et al.: J. Med. Food, 5, 1 (2002), Lanteri, S., et al.: Food Chem., 76, 501 (2002), Rodriguez-Rodriguez, R., et al.: Br. J. Pharmacol., 155, 535 (2008), Sotiroudis, T., et al.: Eur. J. Nutr, 47, 69 (2008),Fórmula:C30H45D3O3Forma y color:NeatPeso molecular:459.722,2-Bis(4-hydroxyphenyl)-1,1,1-trichloroethane
CAS:Producto controladoApplications 2,2-Bis(4-hydroxyphenyl)-1,1,1-trichloroethane is an active metabolite of Methoxychlor that acts via the estrogen receptor (ER) to stimulate estrogen response element (ERE)-mediated gene transcription in estrogen-sensitive tissues. 2,2-Bis(4-hydroxyphenyl)-1,1,1-trichloroethane is used in epoxy resins and other epoxide compositions as industrial materials and electric insulators. References Willard, S. et al.: Res. J. Med. Med. Sci., 4, 171 (2009); Brzozowski, Z.K. et al.: Polimery, 17, 419 (1972); Kielkiewicz, J. et al.: Konf. Kunstst. Masch.-Fahrzeugbau. Vortr., 3, 325 (1973);Fórmula:C14H11Cl3O2Forma y color:NeatPeso molecular:317.59GIP Protein, Human, Recombinant (hFc)
Glucose-dependent insulinotropic polypeptide (GIP) is an incretin that plays an important role in fat accumulation.Forma y color:Lyophilized PowderPeso molecular:34.9 kDa (predicted)3-Keto-N-aminoethyl-N’-aminocaproyldihydrocinnamoyl Cyclopamine
CAS:Producto controladoFórmula:C44H63N3O4Forma y color:NeatPeso molecular:697.99Megestrol-17-acetate 100 µg/mL in Acetonitrile
CAS:Producto controladoFórmula:C24H32O4Forma y color:Single SolutionPeso molecular:384.51(R,S)-Equol
CAS:Producto controladoApplications (R,S)-Equol is a human urinary metabolite of the soy isoflavones Daidzein (D103500). References Heinonen, S., et al.: Anal. Biochem., 274, 211 (1999), Setchell, K., et al.: J. Nutr., 132, 3577 (2002), Thigpen, J., et al.: Comp. Med., 53, 607 (2003), Yee, S., et al.: Food Chem. Toxicol., 46, 2713 (2008),Fórmula:C15H14O3Forma y color:NeatPeso molecular:242.273,3’,5-Triiodo-D-thyronine
CAS:Producto controladoApplications 3,3’,5-Triiodo-D-thyronine is a structural analogue o the thyroid homonef Thyroxine (T425600). 3,3’,5-Triiodo-D-thyronine has been shown to reduce cholesterol in blood serum. References Mintz, D.O., et. al.: New Engl. J. Med., 266, 808 (1962)Fórmula:C15H12I3NO4Forma y color:Off-White To Light BrownPeso molecular:650.97Levonorgestrel 100 µg/mL in Acetonitrile
CAS:Fórmula:C21H28O2Forma y color:Single SolutionPeso molecular:312.45Meteorin-like/METRNL Protein, Human, Recombinant (His & SUMO)
Hormone induced following exercise or cold exposure that promotes energy expenditure.Forma y color:Lyophilized PowderPeso molecular:46.0 kDa (predicted)3a,17b-Androst-5-enediol
CAS:Producto controladoApplications 5-Androstenediol is a steroid androgen metabolite of Testosterone (T155000), the principal hormone of the testes, produced by the interstitial cells. References Miller, M., et al.: Steroids., 78, 15 (2013); Baker, M.E., et al.: Steroids., 77, 1192 (2012); Ronis, M.J.J. et al.: Comp. Biochem. Physiol.-C: Pharmacol. Toxicol. Endocrinol., 121C, 221 (1998);Fórmula:C19H30O2Forma y color:NeatPeso molecular:290.44Fenoxycarb-d3
CAS:Producto controladoApplications A labelled form of Fenoxycarb (F248870), a carbamate insect growth regulator by preventing immature insects from reaching maturity by mimicking juvenile hormone. Used as a standard for Pesticide detection. Fenoxycarb is also used in cannabis testing kits as a component of pesticide mixes (P698235). References El-Saeid, M.H., et al.: J. Chem., 10, (2013); Coors, A., et al.: Environ. Toxicol. Chem., 31, 1239 (2012);Fórmula:C17D3H16NO4Forma y color:White SolidPeso molecular:304.36Fulvestrant 3-Sulfate Sodium Salt
CAS:Producto controladoApplications A metabolite of Fulvestrant (F862500). References Rao, P., et al.: J. Steroid Biochem., 25, 417 (1986), Wakeling, A., et al.: J. Steroid Biochem. Mol. Biol., 43, 173 (1992), DeFriend, D., et al.: Cancer Res., 54, 408 (1994),Fórmula:C32H46F5NaO6S2Forma y color:NeatPeso molecular:708.824-Androsten-17α-methyl-17β-ol-3-one-1,2-d2
CAS:Producto controladoApplications 4-Androsten-17alpha-methyl-17beta-ol-3-one-1,2-d2 is a useful isotopically labeled compound of 17α-Methyl Testosterone (M326400)Fórmula:C20H28D2O2Forma y color:NeatPeso molecular:304.47Testosterone Propionate extrapure, 98%
CAS:Fórmula:C22H32O3Pureza:min. 98%Forma y color:White to off-white, PowderPeso molecular:344.50Testosterone (free base) extrapure, 99%
CAS:Fórmula:C19H28O2Pureza:min. 99%Forma y color:White to off-white, Crystalline powderPeso molecular:288.42Testosterone-16,16,17-d3 Benzoate
CAS:Producto controladoFórmula:C26H29D3O3Forma y color:NeatPeso molecular:395.56Tixocortol
CAS:Producto controladoStability Hygroscopic Applications Tixocortol is an anti-inflammatory agent. Tixocortol is used in fluorescent chemoaffinity labeling. References Torossian, D.R., et al.: Arzneim.-Forsch., 31, 453 (1981),Fórmula:C21H30O4SForma y color:NeatPeso molecular:378.534-Pregnen-17α-ol-3,20-dione-2,2,4,6,6,21,21,21-d8 Hexanoate
CAS:Producto controladoFórmula:C27H32D8O4Forma y color:NeatPeso molecular:436.66Adiponectin Protein, Feline, Recombinant
Adiponectin Protein, Feline, Recombinant is expressed in E.Forma y color:Lyophilized PowderPeso molecular:24.9 kDa (predicted)Fluasterone
CAS:Producto controladoApplications A synthetic derivative of Dehydroepiandrosterone. The reduced androgenicity of Fluasterone may obviate toxicities associated with the androgenicity of the parent compound. Antitumor agent. Used in clinical trials for prostate cancer prevention. References Bentley, P., et al.: Food Chem. Toxicol., 31, 857 (1993), Rao, K., et al.: Cancer Res., 59, 3084 (1999), Masuzaki, H., et al.: Science, 294, 2166 (2001), Osawa, E., et al.: Life Sci., 70, 2623 (2002),Fórmula:C19H27FOForma y color:NeatPeso molecular:290.42Insulin, porcine, recombinant
Insulin Porcine is a two chain, glycosylated polypeptide chain containing 51 amino acids and having a molecular mass of 5777 Dalton. The a and b chains are joined by two interchain disulfide bonds with the a chain containing an intrachain disulfide bond. Insulin regulates the cellular uptake, utilization, and storage of glucose, amino acids, and fatty acids and inhibits the breakdown of glycogen, protein, and fat.Pureza:Min. 95%Testosterone Undecanoate-d3
CAS:Producto controladoApplications A Labelled metabolite of Testosterone (T155000). It is a promising androgen for male hormonal contraception.CONTROLLED SUBSTANCE References Glass, A., et al.: J. Clin. Endocrinol. Metab., 45, 1211 (1977), Behre, H., et al.: Eur. J. Endocrinol., 140, 414 (1999), Nieschlag, E., et al.: Steroids, 68, 965 (2003), Wang, C., et al.: J. Clin. Endocrinol. Metab., 91, 460 (2006),Fórmula:C30H45D3O3Forma y color:NeatPeso molecular:459.72Flunisolide
CAS:Fórmula:C24H31FO6Pureza:>98.0%(HPLC)Forma y color:White to Almost white powder to crystalPeso molecular:434.504-tert-Octylphenol-13C6
CAS:Applications A common environmental pollutant showing weak estrogenic effects. Has been shown to cause harm to the male reproductive system of vertebrates. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Jiao, B., et al.: J. Cell. Biochem., 105, 1399 (2008), Hamelin, G., et al.: J. Toxicol. Environ. Health, Part A: Current Issues, 72, 541 (2009), Brian, J., et al.: Environ. Sci. Technol., 43, 214 (2009),Fórmula:C6C8H22OForma y color:White To Off-WhitePeso molecular:212.286-Defluoro-6-oxo-fluticasone Propionate
Stability Temperature Sensitive Applications 6-Defluro-6-oxo-fluticasone Propionate is a derivative of Flumethasone (F455000), a glucocorticoid, anti-inflammatory. References Matuszewski, B, et al.: Anal. Chem., 75, 3019 (2003), Fekete, S., et al.: J. Pharm. Biomed. Anal., 49, 64 (2009),Fórmula:C25H30F2O6SForma y color:Off-WhitePeso molecular:496.56Corticoliberin Protein, Mouse, Recombinant (His & KSI)
Hormone regulating the release of corticotropin from pituitary gland. Induces NLRP6 in intestinal epithelial cells, hence may influence gut microbiota profile.Forma y color:Lyophilized PowderPeso molecular:20.1 kDa (predicted)Dihydro Dutasteride
CAS:Applications Dihydro Dutasteride is an impurity arose during the process development of Dutasteride (D735000). References Solomons, W., et al.: J. Pharma. Sci., 63, 19 (1974), Rasmusson, G., et al.: J. Med. Chem., 29, 2298 (1986),Fórmula:C27H32F6N2O2Forma y color:WhitePeso molecular:530.5518-Hydroxycortisol (Hemiketal)
CAS:Applications 18-Hydroxycortisol is a derivative of Cortisol (H714615), frequently referred to as the “stress hormone”, is released into the bloodstream during periods of stress. Cortisol also has effects on enhancing memory with regards to emotions during stressful events. References Buchanan, T., et al.: Psychoneuroendocrino, 26, 307 (2001); Stark, R., et al.: Neuroimage, 32, 1290 (2006)Fórmula:C21H30O6Forma y color:White To BeigePeso molecular:378.46(3beta)-Allopregnanolone Sulfate Sodium Salt
CAS:Producto controladoApplications (3β)-Allopregnanolone Sulfate is the sulfate conjugate of (3β)-Allopregnanolone, a metabolite of progesterone and a potent inhibitory modulator of GABAA receptors. References Li, P. et al.: Mol. Pharmacol., 77, 539 (2010); El-Etr, M. et al.: Brain Res., 790, 334 (1998); Park-Chung, M. et al.: Brain Res., 830, 72 (1999);Fórmula:C21H33NaO5SForma y color:NeatPeso molecular:420.54Desoxymetasone-D5 (Major)
CAS:Producto controladoApplications Desoxymetasone-D5 is a labelled analogue of Desoxymetasone (D296970). Desoxymetasone is a fluorinated corticosteroid that is structurally related to Dexamethasone (D298800), and is used as a topical cream to treat eczema. References Heel, R., et al.: Drugs, 16, 302 (1978); Henry, M., et al.: Curr. Med. Res. Opin., 6, 502 (1980); Sehgal, Int. J. Derm., 15, 770 (1976)Fórmula:C22D5H24FO4Forma y color:NeatPeso molecular:381.49(3Alpha,5Beta,7Alpha)-7-Hydroxy-3-(sulfooxy)-cholan-24-oic Acid Disodium Salt
CAS:Producto controladoStability Hygroscopic Applications (3α,5β,7α)-7-Hydroxy-3-(sulfooxy)-cholan-24-oic Acid is the 3-monosulfate derivative of chenodeoxycholic acid (C291900), a major bile acid in many vertebrates, occurring as the N-glycine and/or N-taurine conjugate. References Haslewood, E.S., et al.: Biochem. J., 155, 401 (1976); Parmentier, G., et al.: Steroids., 30, 583 (1977);Fórmula:C24H38Na2O7SForma y color:NeatPeso molecular:516.6GH Protein, Pig, Recombinant (His & Myc)
Plays an important role in growth control.Forma y color:Lyophilized PowderPeso molecular:29.4 kDa (predicted)GH Protein, Rhesus macaque, Recombinant (His & Myc)
Plays an important role in growth control.Forma y color:Lyophilized PowderPeso molecular:29.7 kDa (predicted)
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