Hormonas
Las hormonas son mensajeros bioquímicos producidos por las glándulas en organismos multicelulares que regulan procesos fisiológicos y comportamientos. Estas moléculas de señalización son esenciales para mantener la homeostasis, el crecimiento, el metabolismo y la reproducción. En esta categoría, encontrará una selección completa de hormonas disponibles para fines de investigación, incluyendo esteroides, péptidos y aminas. Estos productos son cruciales para estudiar las funciones endocrinas, desarrollar tratamientos terapéuticos y avanzar en nuestra comprensión de la regulación hormonal en la salud y la enfermedad. En CymitQuimica, proporcionamos hormonas de alta calidad para apoyar sus necesidades de investigación en bioquímica, farmacología y ciencias médicas.
Productos de "Hormonas"
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Icomethasone 21-Mesylate
CAS:Producto controladoImpurity Mometasone Furoate Impurity N / Mometasone EP Impurity N Applications Icomethasone 21-Mesylate is a derivative of Icomethasone (I164100), used in the preparation of Mometasone (M489995).Fórmula:C23H31ClO7SForma y color:Off WhitePeso molecular:487.016beta-Hydroxy Dutasteride
Applications 6β-Hydroxy Dutasteride is a hydroxylated derivative of Dutasteride (D735000).Fórmula:C27H30F6N2O3Forma y color:NeatPeso molecular:544.431,2-Dihydro Dexamethasone Phosphate Disodium Salt
Stability Hygroscopic Applications 1,2-Dihydro Dexamethasone Phosphate Disodium Salt is an impurity of Dexamethasone Phosphate (D298835). References Kodelja, V., et al.: J. Immunol., 160, 1411 (1998), Metselaar, J., et al.: Arthritis Rheum., 48, 2059 (2003), Buttgereit, F., et al.: Arthritis Rheum., 50, 3408 (2004), Martinez, F., et al.: Front Biosci., 13, 453 (2008),Fórmula:C22H30FNa2O8PForma y color:NeatPeso molecular:518.4211β,17α,21-Trihydroxypregn-4-ene-3,20-dione
CAS:Fórmula:C21H30O5Pureza:98%Forma y color:SolidPeso molecular:362.45994-Hydroxy Estradiol 1-N7-Guanine
CAS:Producto controladoApplications 4-Hydroxy Estradiol 1-N7-Guanine is an estrogen metabolite formed with DNA which can lead to the mutations that initiate breast, prostate, and other types of cancer. Estrogen-DNA depurinating adducts as biomarkers of cancer risk and their use in cancer detection and prevention. References Chakravarti, D., et al.: Mutat. Res., 456, 17 (2000), Liehr, J., et al.: Endocr. Rev., 21, 4054 (2000), Chakravarti, D., et al.: Oncogene, 20, 7945 (2001), Cavalieri, E., et al.: Chem. Res. Toxicol., 14, 1041 (2002),Fórmula:C23H27N5O4Forma y color:NeatPeso molecular:437.49(3alpha,17alpha)-4-Chloro-3-hydroxy-17-methyl-18-Norandrosta-4,13-diene-17-methanol
CAS:Producto controladoApplications (3α,17α)-4-Chloro-3-hydroxy-17-methyl-18-Norandrosta-4,13-diene-17-methanol is a metabolite of Dehydrochloromethyltestosterone (DHCMT) and a related compound of clostebol acetate (C587395), an anabolic steroid. References Roy, D., et al.: Eur. J. Med. Chem., 42, 1365 (2007); Alvarez-Ginarte, Y., et al.: Bioorg. Med. Chem., 16, 6448 (2008); Srivastava, H., et al.: Med. Chem. Res., 18, 455 (2009)Fórmula:C20H29ClO2Forma y color:NeatPeso molecular:336.9Tixocortol 21-Pivalate
CAS:Producto controladoApplications Tixocortol 21-Pivalate is an anti-inflammatory agent. Tixocortol 21-Pivalate is used in fluorescent chemoaffinity labeling. References Torossian, D.R., et al.: Arzneim.-Forsch., 31, 453 (1981),Fórmula:C26H38O5SForma y color:NeatPeso molecular:462.64Dimethazine
CAS:Producto controladoApplications Diamethazine is an C17-alkylated, anabolic-androgenic steroid, that exhibits similar effects to Superdrol (M226010). References Orlandi, F., et al.: Adv. Hepatol. Trans. Int. Symp. Int. Assoc. Study Liver., 109 (1965); Shakoori, A. R, et al.: Proceeding. Congress. Zool., 24, 1 (2004);Fórmula:C42H68N2O2Forma y color:NeatPeso molecular:633.00Lysipressin-d5 Trifluoroacetic Acid Salt
CAS:Producto controladoStability Hygroscopic Applications Isotope labelled Lysipressin (L488770) is an analog of Vasopressin (A769550), a powerful vasopressor used to modulate blood pressure. An endogenous antidiuretic hormone in most mammalian species. It is released into the blood from nerve terminals in the posterior pituitary and median eminence. It is a neurotransmitter in the central nervous system and also implicated in a variety of physiological processes such as regulating water balance by antidiuretic action. References Perucca, J. et al.: J. AM. Soc. Nephrol., 19, 1721 (2008); Toba, K. et al.: Prog. Brain Res., 119, 337 (1998); Berrada, K. et al.: J. Biol. Chem., 275, 27229 (2000);Fórmula:C46H60D5N13O12S2•x(C2HF3O2)Forma y color:NeatPeso molecular:1061.2511402Triptorelin Acetate
CAS:Producto controladoStability Hygroscopic Applications Synthetic peptide agonist analog of LH-RH. Triptoreline is a potent agonist of LH-releasing hormone, currently used in the treatment of prostatic cancer where therapy may be required over months or years. Antineoplastic (hormonal). Used in the treatment of endometriosis and infertility. References Sanders, L., et al.: Eur. J. Drug Metab. Pharmacokinet., 15, 95 (1990), Chiba, M., et al.: Biomaterials, 18, 893 (1997), Blanco, D., et al.: Eur. J. Pharm. Biopharm., 45, 285 (1998), Sinha, V., et al.: J. Control. Rel., 90, 261 (2003),Fórmula:C64H82N18O13·xC2H4O2Forma y color:NeatPeso molecular:1371.50Dydrogesterone-d6 (Major)
CAS:Producto controladoApplications Labelled Dydrogesterone. A synthetic progestin largely used in hormone therapy, on the central nervous system by studying two markers of the neuroendocrine function: the neurosteroid allopregnanolone and the opioid .beta.-endorphin. Progestogen. References Bernardi, F., et al.: Eur. J. Endocrinol., 138, 316 (1998), Rupprecht, R., et al.: Steroids, 64, 83 (1999), Uzunova, V., et al.: Brain Res., 976, 1 (2003), Pluchino, N., et al.: J. Steroid Biochem. Mol. Biol., 102, 205 (2006),Fórmula:C21H22D6O2Forma y color:NeatPeso molecular:318.48Progesterone extrapure, 97-103%
CAS:Fórmula:C21H30O2Pureza:min. 97%Forma y color:White to off-white, Crystalline powderPeso molecular:314.46Chorionic Gonadotropin/CGA Protein, Human, Recombinant (His)
Chorionic Gonadotropin/CGA Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.Forma y color:Lyophilized PowderPeso molecular:11.6 kDa (predicted); 25.9 kDa (reducing conditions)Delta6-Gestodene
Producto controladoApplications Δ6-Gestodene, is an impurity of Gestodene (G368250), an orally active gestogen with progesterone-like profile of activity. Used in combination with estrogen as oral contraceptive. References Duesterberg, B., et al.: Contraception, 24, 673 (1981); Duesterberg, B., et al.: Seroids, 43, 43 (1984); Losert, W., et al.: Arzneim.-Forsch., 35, 459 (1985);Fórmula:C21H24O2Forma y color:NeatPeso molecular:308.414-Hydroxy Estrone-d4
CAS:Producto controladoApplications A labelled metabolite of Estradiol. References Fishman, H.G, et al.: Biochemistry, 8, 4304 (1969), Ryan, Sugar, J., et al.: J. Clin. Endocrinol. Metab., 50, 137 (1980), Numazawa, M., et al.: Steroids, 38, 149 (1981), Travis, R., et al.: Breast Cancer Res., 5, 239 (2003),Fórmula:C182H4H18O3Forma y color:NeatPeso molecular:290.39Clobetasol 17-Propionate-d5
CAS:Producto controladoApplications Clobetasol 17-Propionate-d5 is labelled Clobetasol 17-Propionate (C583500) which is a topical corticosteroid. Clobetasol 17-Propionate (C583500) is anti-inflammatory. References Olsen, E.A., et al.: J. Am. Acad. Dermatol., 15, 246 (1986),Fórmula:C25H27D5ClFO5Forma y color:NeatPeso molecular:472.02,2’-[5-(1H-1,2,4-Triazol-1-yl)methylbenzene-1,3-diyl]bis(2-methylpropanamide)
CAS:Forma y color:NeatBis-(6Alpha-Methylprednisolone) 21,21’-Ether
Producto controladoFórmula:C44H58O9Forma y color:NeatPeso molecular:730.94Methyl Lithocholate
CAS:Producto controladoApplications Methyl Lithocholate is an derivative of Lithocholic Acid (L469180),a cholic acid derivative as TGR5 modulator. Found in ox bile, human bile, rabbit bile, and in ox and pig gallstones. References Roleira, F.M., et al.: Lett. Drug. Design. Discovery., 7, 610 (2010);Fórmula:C25H42O3Forma y color:NeatPeso molecular:390.603,3’,5-Triiodo-L-thyronine-13C6
CAS:Applications One of the hormones produced by the thyroid gland that is involved in the maintenance of metabolic homeostasis. Also produced in peripheral tissues as the active metabolite of Thyroxine. References Gross, J., et al.: Lancet I, 439 (1952), Roche, J., et al.: Biochim. Biophys. Acta, 11, 215 (1953), Chacon, M.A., et al.: J. Pediatr., 99, 758 (1981), Chopra, I.J., et al.: Thyroid, 6, 255 (1996),Fórmula:C6C9H12I3NO4Forma y color:Beige To BrownPeso molecular:656.9321-Chloro-9,11β-epoxy-16α-methyl-3,20-dioxo-9β-pregna-1,4-dien-17-yl Furan-2-carboxylate
CAS:Fórmula:C27H29ClO6Glycodeoxycholic Acid-3-O-Beta-glucuronide Disodium Salt
CAS:Producto controladoFórmula:C32H49NNa2O11Forma y color:NeatPeso molecular:669.7117Beta-Estradiol-13C2
CAS:Producto controladoApplications Isotope labelled 17β-Estradiol (E888000), which is the major estrogen (1) secreted by the premenopausal ovary (2).Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA), environmental, and food contaminants. References 1. Salole, E. et al.: Anal. Profiles Drug Subs. 1986 15, 23 283-3182. Lievertz, R. et al.: Am. J. Obstet. Gynecol. 1987 May;156(5):1289-93.Fórmula:C2C16H24O2Forma y color:WhitePeso molecular:274.37Beclomethasone-d5
CAS:Producto controladoApplications Glucocorticoid. Used in chronic asthma and allergic rhinitis. Antiallergic, antiasthmatic (inhalant). Anti-inflammatory (topical). References Malfitan, V.A., et al.: Clin. Ther., 4, 472 (1982), Rao, M., et al.: J. Asthma, 19, 21 (1982), Small, P., et al.: Ann. Allergy, 49, 127 (1982), Brogden, R.N., et al.: Drugs, 28, 99 (1984),Fórmula:C22H24D5ClO5Forma y color:NeatPeso molecular:413.95Finasteride 2-(2-Methylpropanol)amide
CAS:Producto controladoFórmula:C23H36N2O3Forma y color:NeatPeso molecular:388.54Tauro-b-muricholic Acid-d4 Sodium Salt
CAS:Producto controladoStability Hygroscopic Applications Sodium salt of Tauro-α-muricholic Acid is a labeled bile acid released by the liver and is typically used in cholestasis studies. References Yang, L. et al.: Chem. Res. Toxicol., 21, 2280 (2008); Holm, R. et al.: Phys. Chem. Chem. Phys., 11, 5070 (2009);Fórmula:C26H40D4NNaO7SForma y color:White To Off-WhitePeso molecular:541.716Beta-Hydroxy Budesonide-d8
CAS:Producto controladoApplications A labelled metabolite of Budesonide (B689490), a non-halogenated glucocorticoid related to triamcinolone hexacetonide. Used as an antiinflammatory agent. References Ryrfeldt., A., et a.: J. Steroid Biochem., 10, 317 (1979), Roth, G., et al.: J. Pharm. Sci., 69, 766 (1980), Edsbaecker, S., et al.: Drug Metab. Dispos., 15, 412 (1987),Fórmula:C25H26D8O7Pureza:~90%Forma y color:NeatPeso molecular:454.58Prednisolone phosphate sodium
CAS:Fórmula:C21H27Na2O8PPureza:97%Forma y color:SolidPeso molecular:484.38764-Pregnen-6α-methyl-17-ol-3,20-dione-2,2,4,6,21,21,21-d7 17-Acetate
CAS:Producto controladoFórmula:C24H27D7O4Forma y color:NeatPeso molecular:393.57Methyl 4-(2-Hydroxyethoxy)benzoate
CAS:Producto controladoFórmula:C10H12O4Forma y color:NeatPeso molecular:196.206Beta,17Alpha-Dihydroxyprogesterone
CAS:Producto controladoFórmula:C21H30O4Forma y color:NeatPeso molecular:346.46
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