
Moduladores GABA
Los moduladores de GABA son compuestos que influyen en la función de los receptores de GABA (ácido gamma-aminobutírico), los principales receptores inhibitorios de neurotransmisores en el sistema nervioso central. Estos moduladores pueden aumentar o inhibir la actividad GABAérgica, afectando la excitabilidad neuronal y la transmisión sináptica. Los moduladores de GABA son cruciales en el tratamiento y estudio de varios trastornos neurológicos y psiquiátricos, incluyendo ansiedad, epilepsia e insomnio. En CymitQuimica, ofrecemos una amplia gama de moduladores de GABA para apoyar su investigación en neurociencia, farmacología y neuroterapéutica.
Productos de "Moduladores GABA"
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3-Hydroxy Prazepam
CAS:Producto controladoApplications 3-Hydroxy-prazepam is a metabolite of Prazepam (P702250), a benzodiazepine commonly prescribed to treat anxiety. References Kingstone, E.,et al.: Curr. Ther. Res. Clin. E., 8, 159 (1966); Lemoine, P., et al.: Pharmacopsychiatry, No vol. given, No pp. given, (1991);Fórmula:C19H17ClN2O2Forma y color:NeatPeso molecular:340.808-Bromo-3,4-dihydro-1H-benzo[e][1,4]diazepin-5(2H)-one
CAS:Pureza:97.0%Peso molecular:241.087997436523447-Hydroxy-furo[3,4-b]pyrazin-5-one, 70%
CAS:Producto controladoApplications 7-Hydroxy-furo[3,4-b]pyrazin-5-one is a derivative of 6-(5-Chloro-2-pyridyl)-6,7-dihydro-7-hydroxy-5H-pyrrolo[3,4-b]pyrazin-5-one (C379925) which is an impurity of Eszopiclone (E889150), a nonbenzodiazepine hypnotic agent used as a treatment for insomnia. References Gottesmann, C., et al.: Eur. J. Neurosci., 10, 409 (1998), Yoshimoto, M., et al.: Eur. Neuropsychopharmacol., 9, 29 (1999),Fórmula:C6H4N2O3Pureza:70%Forma y color:NeatPeso molecular:152.11Eszopiclone
CAS:Producto controladoApplications Eszopiclone is the active stereoizomer of Zopiclone and belongs to the class of drug known as cyclopyrrones. It is a nonbenzodiazepine hypnotic agent used as a treatment for insomnia.This is a controlled substance (depressant) in the US but not in Canada. References Gottesmann, C., et al.: Eur. J. Neurosci., 10, 409 (1998), Yoshimoto, M., et al.: Eur. Neuropsychopharmacol., 9, 29 (1999),Fórmula:C17H17ClN6O3Forma y color:Off WhitePeso molecular:388.812,2-Dipropylpentanoic Acid
CAS:Producto controladoFórmula:C11H22O2Forma y color:NeatPeso molecular:186.29Pridinol Methanesulfonate Salt
CAS:Producto controladoApplications Used as an antiparkinsonian agent and as an anticholinergic. References Duperray, B., et al.: Eur. J. Drug Metab. Pharmacokinet., 2, 121 (1977),Fórmula:C20H25NO·CH4O3SForma y color:White To Off-WhitePeso molecular:391.521’-Hydroxy Midazolam (100 ug/mL in methanol)
CAS:Producto controladoFórmula:C18H13ClFN3OForma y color:Single SolutionPeso molecular:341.77Talbutal-d5
CAS:Producto controladoApplications A labelled stuctural isomer of Butalbital (B690100). A short to intermediate-acting barbiturate that act as nonselective depressants of the central nervous system (CNS). Sedative, hypnotic. Controlled Substance. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Nielsen, C.J. et al.: Pharmacol., 26, 371 (1925); Lien, E.J. et al.: Acta Pharmac. Jug., 34, 123 (1984);Fórmula:C11H11D5N2O3Forma y color:NeatPeso molecular:229.294-Hydroxy Triazolam
CAS:Producto controladoStability Light Sensitive Applications A metabolite of Triazolam (T767380). References Gall, M., et al.: J. Med. Chem., 21, 1290 (1978), Jones, H., et al.: Drug Metab. Dispos., 32, 973 (2004), Hallifax, D., et al.: Drug Metab. Dispos., 33, 1852 (2005).Fórmula:C17H12Cl2N4OForma y color:NeatPeso molecular:359.21Barbituric Acid-13C,15N2
CAS:Producto controladoApplications Parent compound of barbiturate drugs. References Luo, Y., et al.: J. Med. Chem., 53, 3846 (2010), Tomasic, T., et al.: Eur. J. Med. Chem., 45, 1667 (2010), Gilbert, A., et al.: Bioorg. Med. Chem. Lett., 20, 636 (2010),Fórmula:C313CH415N2O3Forma y color:NeatPeso molecular:131.075H-Dibenzo[b,f]azepine (Iminostilbene)
CAS:Producto controladoFórmula:C14H11NForma y color:NeatPeso molecular:193.24