Moduladores GABA
Los moduladores de GABA son compuestos que influyen en la función de los receptores de GABA (ácido gamma-aminobutírico), los principales receptores inhibitorios de neurotransmisores en el sistema nervioso central. Estos moduladores pueden aumentar o inhibir la actividad GABAérgica, afectando la excitabilidad neuronal y la transmisión sináptica. Los moduladores de GABA son cruciales en el tratamiento y estudio de varios trastornos neurológicos y psiquiátricos, incluyendo ansiedad, epilepsia e insomnio. En CymitQuimica, ofrecemos una amplia gama de moduladores de GABA para apoyar su investigación en neurociencia, farmacología y neuroterapéutica.
Productos de "Moduladores GABA"
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Desmethyldiazepam-D5 (Nordazepam-D5), 1mg/ml in Methanol
CAS:Producto controladoFórmula:C152H5H6ClN2OMethylbarbital
CAS:Producto controladoApplications Methylbarbital is a barbituate which displays anticonvulsant/antiepileptic activity. References Lien, E. et al.: J. Pharm. Sci.., 68, 463 (1979); Kesselheim, A. et al.: Drugs, 70, 605 (2010);Fórmula:C9H14N2O3Forma y color:WhitePeso molecular:198.221-Methyl-5-phenyl-1,3-dihydro-2H-benzo[e][1,4]diazepin-2-one
CAS:Pureza:98%Peso molecular:250.30099487304688Pentobarbital
CAS:Producto controladoApplications Pentobarbital is a narcotic and sedative barbiturate drug formerly used to relieve insomnia. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Schafer, E.W., et al.: Toxicol. Appl. Pharmacol., 21, 315 (1972), Woster, P.S., et al.: Clin. Pharm., 9, 762 (1990), Evans, A.T., et al.: J. Am. Vet. Med. Assoc., 203, 664 (1993),Fórmula:C11H18N2O3Forma y color:NeatPeso molecular:226.27Allobarbital-d10
CAS:Producto controladoApplications Labelled Allobarbital, a barbiturate derivative that is primarily used as an anticonvulsant. Allobarbital also shows hypnotic activity and is used to boost the activity of analgesic drugs. Studies show that Allobarbital is an effective promoters of hepatocarcinogenesis. Allobarbital is a Controlled Substance. References Tateoka, Y. et al.: Yakug. Zas., 106, 504 (1986); Crawford, J.M. et al.: Neuropharmacology, 9, 31 (1970); Rice, J.M. et al.: Carcinogenesis, 15, 395 (1994);Fórmula:C10D10H2N2O3Forma y color:White To Off-WhitePeso molecular:218.275Clozapine N-Oxide
CAS:Producto controladoImpurity CLOZAPINE N-OXIDE IMPURITY Applications Clozapine N-Oxide is a 5-HT2 antagonist. It is a major metabolite of clozapine (C587500) that can be monitored by HPLC. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Baldessarini, E., et al.: Neuropsychopharmacol., 9, 117 (1993); Lin, G., et al.: J. Pharm. Sci, 83, 1412 (1994); Roth, B.L., et al.: J. Pharmacol. Exp. Ther., 268, 1403 (1994)Fórmula:C18H19ClN4OForma y color:Light Yellow To YellowPeso molecular:342.82Valproic Acid EP Impurity E
CAS:Producto controladoFórmula:C5H11NOForma y color:NeatPeso molecular:101.15Clorazepic Acid Ethyl Ester
CAS:Producto controladoApplications Clorazepic Acid Ethyl Ester is an ethyl ester of Clorazepic Acid (C587365, Dipotassium Salt) which is an anxiolytic. References Cone, E., et al.: J. Pharm. Sci., 73, 243 (1984), Maurer, H., et al.: J. Anal. Toxicol., 25, 237 (2001), Beyer, J., et al.: Ther. Drug Monit., 27, 151 (2005)Fórmula:C18H15ClN2O3Forma y color:White To Light YellowPeso molecular:342.78
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