Sales y derivados de API
Las sales de los Ingredientes Farmacéuticos Activos (API) son compuestos formados por la reacción de un ácido con una base, resultando en un equilibrio iónico. Estas sales suelen mejorar la solubilidad y estabilidad de los APIs, facilitando su absorción en el cuerpo. Los derivados de API son variantes químicas de un principio activo que pueden tener propiedades mejoradas o modificadas para optimizar su eficacia terapéutica. Las sales de APIs se utilizan en la formulación de medicamentos orales, inyectables y tópicos. Además, los derivados de APIs pueden mejorar la farmacocinética de los fármacos, como la liberación controlada de activos.
En CymitQuimica contamos con sales y derivados de APIs con la pureza y calidad necesarias para investigación y desarrollo de formulaciones farmacéuticas.
Productos de "Sales y derivados de API"
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Beta-Nicotinic Acid Mononucleotide-d4
CAS:Producto controladoStability Hygroscopic Applications β-Nicotinic Acid Mononucleotide-d4 is the isotope labelled analog of β-Nicotinic Acid Mononucleotide (N429390); a nucleotide of nicotinic acid which is produced from quinolinic acid by quinolinate phosphoribosyltransferase via transfer of a phosphoribose group. It is an intermediate of nicotinic acid adenine dinucleotide (NaAD) which is then converted to NAD via amidation and in turn converted to NADPH. References Petrelli, R. et al.: Curr. Med. Chem., 18, 1973 (2011); Shibata, K. et al.: J. Chrom. B Biomed. Sci. Appl., 749, 281 (2000); Evans, C. et al.: BMC Chem. Biol., 10, 2 (2010)Fórmula:C11H10D4NO9PPureza:>90%Forma y color:NeatPeso molecular:339.23H-Phe(4-N3)-OH
CAS:Fórmula:C9H10N4O2Pureza:>95.0%(T)(HPLC)Forma y color:White to Brown powder to crystalPeso molecular:206.21Moxifloxacin Acyl Glucuronide
CAS:Fórmula:C27H32FN3O10Forma y color:Off-White SolidPeso molecular:577.56Maleimide-C2-Amido-PEG4-Carboxylic Acid tert-Butyl Ester
CAS:Fórmula:C22H36N2O9Pureza:>98.0%(HPLC)Forma y color:Colorless to Light yellow clear liquidPeso molecular:472.54Dimetindene N-Oxide Maleate (N,N-Dimethyl N-Oxide)
CAS:Fórmula:C20H24N2O·C4H4O4Forma y color:Off-White SolidPeso molecular:308.43 116.07Cholic Acid Ethyl Ester
CAS:Producto controladoFórmula:C26H44O5Forma y color:WhitePeso molecular:436.62Sodium Gualenate (Guaiazulene 3-Sulfonate Sodium Salt)
CAS:Fórmula:C15H17O3S·NaForma y color:Black Blue SolidPeso molecular:277.36 22.992-Ethynyl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
CAS:Fórmula:C8H13BO2Pureza:>95.0%(GC)Forma y color:White or Colorless to Yellow powder to lump to clear liquidPeso molecular:152.002,3,4-Trimethoxybenzyl Alcohol
CAS:Producto controladoImpurity Trimetazidine EP impurity D Applications 2,3,4-Trimethoxybenzyl Alcohol is a trimethoxylated aromatic alcohol. 2,3,4-Trimethoxybenzyl Alcohol is an impurity of the anti-anginal drug Trimetazidine (T795610). References Medenica, M.B. et al.: J. Chrom. Sci., 46, 430 (2008);Fórmula:C10H14O4Forma y color:Clear Colourless To Light YellowPeso molecular:198.22Ticagrelor Impurity 83
CAS:Fórmula:C23H28F2N6O6SForma y color:White To Off-White SolidPeso molecular:554.571-Carbobenzoxy-4-piperidinecarboxylic Acid
CAS:Fórmula:C14H17NO4Pureza:>97.0%(GC)(T)Forma y color:White to Almost white powder to crystalPeso molecular:263.29Docetaxel
CAS:Fórmula:C43H53NO14Pureza:>98.0%(HPLC)Forma y color:White to Almost white powder to crystalPeso molecular:807.89N-Oleoylsarcosine
CAS:Fórmula:C21H39NO3Forma y color:Light yellow to Brown clear liquidPeso molecular:353.55D,L-Trihexyphenidyl Hydrochloride-D11
CAS:Producto controladoFórmula:C20H21D11ClNOForma y color:Off White SolidPeso molecular:348.99Azithromycin N-Oxide
CAS:Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoiFórmula:C38H72N2O13Forma y color:White Crystalline PowderPeso molecular:764.503442-Bromo (S)-Carbidopa
CAS:Applications 2-Bromo (S)-Carbidopa is an impurity of Carbidopa (C175915), a prodrug inhibitor of aromatic amino acid decarboxylase. References Sletzinger, M., et al.: J. Med. Chem., 6, 101 (1963)Fórmula:C10H13BrN2O4Forma y color:NeatPeso molecular:305.13Leflunomide EP Impurity H (Teriflunomide EP Impurity B, Teriflunomide USP Related Compound B)
CAS:Fórmula:C10H7F3N2OForma y color:Off-White SolidPeso molecular:228.172-Hydroxybenzimidazole
CAS:Producto controladoImpurity Lansoprazole EP Impurity D (Rabeprazole EP Impurity K) Applications 2-Hydroxybenzimidazole (Lansoprazole EP Impurity D(Rabeprazole EP Impurity K)) is a metabolite of the neuroleptic Droperidol (D679500). References Chen, Y., et al.: Int. J. Pharm., 137, 149 (1996), Cronin, M., et al.: J. Pharm. Pharmacol., 50, 143 (1998), Luan, F., et al.: Pharm. Res., 22, 1454 (2005),Fórmula:C7H6N2OForma y color:Light BrownPeso molecular:134.14Ethylene Glycol 1,2-Bis(2-propynyl) Ether
CAS:Fórmula:C8H10O2Pureza:>97.0%(GC)Forma y color:White to Yellow to Green clear liquidPeso molecular:138.174-Methylbenzenesulfonic Acid Hydrate
CAS:Producto controladoImpurity Lisinopril EP Impurity B/ Anastrozole EP Impurity F Applications 4-Methylbenzenesulfonic Acid Monohydrate (Lisinopril EP Impurity B) is used in the synthesis of resveratrol. Also used in the synthesis of oxane derivatives as antimalarial agents. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Davis, M. et al.: Org. Prep. Proc. Int., 45, 304 (2013); Wang, X. et al.: J. Med. Chem., 56, 2547 (2013);Fórmula:C7H8O3S·H2OForma y color:WhitePeso molecular:190.223-Allyl Naloxone-d5
CAS:Producto controladoApplications 3-Allyl Naloxone-d5 is labelled 3-Allyl Naloxone (A558800) which is an impurity of Naloxone (N285000), a specific opioid antagonist and narcotic antagonist. References Jasinski, D.R., et al.: J. Pharmacol. Exp. Ther., 157, 420 (1967), McNicholas, L.F., et al.: Drugs, 27, 81 (1984), Hasson, M.M.A., et al.: Anal. Profiles Drug Subs., 14, 453 (1985), Stowe, C., et al.: Ann. Pharmacother., 27, 447 (1993),Fórmula:C22D5H20NO4Forma y color:NeatPeso molecular:372.469(+)-MK 801 Maleate
CAS:Fórmula:C16H15N·C4H4O4Pureza:>98.0%(HPLC)Forma y color:White to Light yellow powder to crystalPeso molecular:337.38Bisoprolol-d5 Hemifumarate
CAS:Fórmula:C18H26D5NO4·5C4H4O4Forma y color:White To Off-White SolidPeso molecular:330.48 0.5*116.075-Benzyloxy Propranolol-d5 Hydrochloride
Producto controladoApplications 5-Benzyloxy Propranolol-d5 Hydrochloride is an intermediate in synthesizing 5-Hydroxy Propranolol-d5 (H952542), a labelled metabolite of Propranolol. References Otton, S., et al.: Br. J. Clin. Pharmacol., 30, 751 (1990); Fujita, S., et al.: J. Pharmacol. Exp. Ther., 264, 226 (1993); Bichara, N., et al.: Drug Metab. Dispos., 24, 112 (1996); Tasaki, T., et al.: J. Biochem., 123, 162 (1998)Fórmula:C23H22D5NO3•HClForma y color:NeatPeso molecular:370.503646Vonoprazan Impurity 16 HCl
CAS:Fórmula:C16H13FN2O3S·HClForma y color:Pale Purple SolidPeso molecular:332.35 36.461-Nonadecanol
CAS:Producto controladoApplications 1-Nonadecanol (cas# 1454-84-8) is a useful research chemical.Fórmula:C19H40OForma y color:NeatPeso molecular:284.52(2RS)-2-(Cyclohex-1-enyl)-2-(4-methoxyphenyl)-N,N-dimethylethanamine Hydrochloride
CAS:Fórmula:C17H25NO·ClHFebuxostat Impurity 35
CAS:Fórmula:C12H9NO4SForma y color:White To Off-White SolidPeso molecular:263.272,3,3',4,4',5,6-Heptabromodiphenyl Ether
CAS:Fórmula:C12H3Br7OForma y color:Off-White SolidPeso molecular:722.48
