Sales y derivados de API
Las sales de los Ingredientes Farmacéuticos Activos (API) son compuestos formados por la reacción de un ácido con una base, resultando en un equilibrio iónico. Estas sales suelen mejorar la solubilidad y estabilidad de los APIs, facilitando su absorción en el cuerpo. Los derivados de API son variantes químicas de un principio activo que pueden tener propiedades mejoradas o modificadas para optimizar su eficacia terapéutica. Las sales de APIs se utilizan en la formulación de medicamentos orales, inyectables y tópicos. Además, los derivados de APIs pueden mejorar la farmacocinética de los fármacos, como la liberación controlada de activos.
En CymitQuimica contamos con sales y derivados de APIs con la pureza y calidad necesarias para investigación y desarrollo de formulaciones farmacéuticas.
Productos de "Sales y derivados de API"
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rac-Pregabalin
CAS:Producto controladoApplications A GABA analogue used as an anticonvulsant.Controlled substance in the United States.Not controlled in Germany References Taylor, C.P., at al.: Epilepsy Res., 14, 11 (1993), Field, M.J., et al.: Pain, 80, 391 (1999)Fórmula:C8H17NO2Forma y color:White SolidPeso molecular:159.23(+)-Isolysergic Acid Diethylamide-d10
CAS:Producto controladoStability Hygroscopic Applications (+)-Isolysergic Acid Diethylamide-d10 is labelled iso-LSD (I821060) which is an inactive diastereomer of the illicit psychedelic drug LSD, a potent hallucinogen and non-selective serotonin receptor agonist. References Hoffer, et al.: Clin. Pharmacol. Ther., 6, 183 (1965), Keller, U., et al.: Biochemistry, 27, 6164 (1988), Mey, G., et al.: Mol. Microbiol., 46, 305 (2002), Steiner, U., et al.: Planta, 224, 533 (2006),Fórmula:C20H15D10N3OForma y color:NeatPeso molecular:333.49Dapoxetine-d7 HCl
CAS:Fórmula:C21H16D7NO·HClForma y color:White To Off-White SolidPeso molecular:312.46 36.46Ethyl 1-Ethyl-6,7,8-trifluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylate
CAS:Fórmula:C14H12F3NO3Pureza:>98.0%(GC)Forma y color:White to Almost white powder to crystalPeso molecular:299.25Candesartan Cilexetil Related Compound A (Ethyl 1-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-2-ethoxybenzimidazole-7-carboxylate)
Heterocyclic compounds with nitrogen hetero-atom(s) only, aromatic or modified aromatic, nesoiFórmula:C26H24N6O3Forma y color:PowderPeso molecular:468.19099Methotrexate Hexaglutamate Trifluoroacetate
CAS:Stability Hygroscopic Applications Methotrexate Hexaglutamate is a metabolite of Methotrexate (M260675); a folic acid antagonist, antineoplastic, and antirheumatic. References Freeman, M.V., J. Pharmacol. Exp. Ther., 122, 154 (1958); Weinblass, M.E., et al.: N. Engl. J. Med., 312, 818 (1985)Fórmula:C45H57N13O20·x(C2HF3O2)Forma y color:Yellow SolidPeso molecular:1214.037-Amino-3-[(5-methyl-1,3,4-thiadiazol-2-ylthio)methyl]-3-cephem-4-carboxylic Acid
CAS:Producto controladoImpurity Cefazolin EP Impurity A Applications 7-Amino-3-[(5-methyl-1,3,4-thiadiazol-2-ylthio)methyl]-3-cephem-4-carboxylic Acid (Cefazolin EP Impurity A) is a substrate used in the assessment of immobilized PGA orientation and in the synthesis of beta lactam antibiotics. References Serra, I. et al.: Anal. Bioanal. Chem., 405, 745 (2013); Terreni, M. et al.: App. Microbiol. Biotech., 77, 579 (2007); Kurochkina, V. et al.: Biocat. Biotransform., 20, 35 (2002)Fórmula:C11H12N4O3S3Forma y color:NeatPeso molecular:344.43D-Allothreonine
CAS:Fórmula:C4H9NO3Pureza:>99.0%(T)(HPLC)Forma y color:White to Almost white powder to crystalPeso molecular:119.12Uridine (1-β-D-Ribofuranosylpyrimidine-2,4(1H,3H)-dione)
CAS:Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoiFórmula:C9H12N2O6Forma y color:PowderPeso molecular:244.06954Di-2-thienylmethanone
CAS:Di-2-thienylmethanone is a pyrazole with an activation energy of about 10.5 kcal/mol. It has been found to be toxic and can cause cell lysis. This molecule has been used in the synthesis of a number of drugs, including thiopental, a barbiturate that is used as an anaesthetic. Di-2-thienylmethanone is also the precursor for the synthesis of fluoroquinolones, which are potent antibacterial agents. The Friedel-Crafts reaction is one way this molecule is synthesized, and it involves the addition of an alkyl halide to an unsaturated double bond. This reaction is named after Charles Friedel and James Crafts who first discovered it in 1877.Fórmula:C9H6OS2Pureza:Min. 95%Forma y color:White PowderPeso molecular:194.28 g/mol6-Demethyl Papaverine-d3
CAS:Producto controladoApplications A labelled metabolite of Papaverine (P190500). Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Belpaire, F.M., et al.: Xenobiotica, 8, 297 (1978),Fórmula:C19H16D3NO4Forma y color:NeatPeso molecular:328.38Nα-Tosyl-L-arginine
CAS:Fórmula:C13H20N4O4SPureza:min. 98.0 area%(HPLC)Forma y color:White to Almost white powder to crystalPeso molecular:328.39N-Des(o-tolyl)-N-(m-tolyl) Metolazone
CAS:Producto controladoApplications N-Des(o-tolyl)-N-(m-tolyl) Metolazone is an impurity of Metolazone (M338750); a diuretic and antihypertensive agent. References Curry, C.L., et al.: Clin. Ther., 9, 47 (1986); Kiyingi, A., et al.: Lancet, 335, 29 (1990)Fórmula:C16H16ClN3O3SForma y color:NeatPeso molecular:365.83Bromotris(dimethylamino)phosphonium Hexafluorophosphate
CAS:Fórmula:C6H18BrF6N3P2Pureza:>98.0%(T)(HPLC)Forma y color:White to Almost white powder to crystalPeso molecular:388.07
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