
Cycle cellulaire/point de contrôle
Les inhibiteurs du cycle cellulaire/des points de contrôle sont des composés qui perturbent la progression normale du cycle cellulaire, en particulier aux points de contrôle régulateurs clés. Ces inhibiteurs sont cruciaux pour étudier la division cellulaire, comprendre la prolifération des cellules cancéreuses et développer des thérapies anticancéreuses. En ciblant des phases spécifiques du cycle cellulaire, ces inhibiteurs peuvent induire un arrêt du cycle cellulaire, conduisant à l'apoptose ou à la sénescence des cellules à division rapide. Chez CymitQuimica, nous offrons une large gamme d'inhibiteurs de haute qualité du cycle cellulaire/des points de contrôle pour soutenir vos recherches en biologie du cancer, biologie cellulaire et développement de médicaments.
Sous-catégories appartenant à la catégorie "Cycle cellulaire/point de contrôle"
- Aurora Kinase
- CDK
- Arrêt du cycle cellulaire
- Chk
- c-Myc
- Dynamine
- DYRK
- Ferroptose
- HSP
- Intégrine
- Kinésine
- KSP
- LIM Kinase
- Microtubules associés
- PKC
- PLK
- Rho
- ROCK
- Wee1
Affichez 11 plus de sous-catégories
Produits appartenant à la catégorie "Cycle cellulaire/point de contrôle"
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CDK9-IN-9
CAS :CDK9-IN-9 is a potent and selective CDK9 inhibitor (IC50: 1.8 nM) with anti-cancer activity. It inhibits CDK2 (IC50: 155 nM).Formule :C22H23F2N5O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :459.51GSK-923295
CAS :GSK923295 is a selective allosteric inhibitor of CENP-E kinesin motor ATPase(Ki=3.2 nM).Formule :C32H38ClN5O4Degré de pureté :96.22% - 98.02%Couleur et forme :SolidMasse moléculaire :592.13Ref: TM-T2039
1mg49,00€2mg70,00€5mg97,00€10mg168,00€25mg331,00€50mg510,00€100mg737,00€1mL*10mM (DMSO)136,00€Poloxin
CAS :Poloxin is a non-ATP competitive Polo-like Kinase 1 inhibitor. It targets the polo-box domain (IC50: appr 4.8 μM).Formule :C18H19NO3Degré de pureté :99.19%Couleur et forme :SolidMasse moléculaire :297.35GSK 3008348 hydrochloride
CAS :GSK 3008348 hydrochloride is an αvβ6 integrin inhibitor used to confirm idiopathic pulmonary fibrosis.Formule :C29H37N5O2xHClDegré de pureté :99.54%Couleur et forme :SolidMasse moléculaire :0LY2812223
CAS :LY2812223: selective mGlu2 agonist; binds mGlu2/mGlu3 (Ki=144/156 nM).Formule :C10H12N4O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :284.29(R)-Enitociclib
CAS :(R)-Enitociclib, an enantiomer of BAY-1251152, is a CDK9 inhibitor with anticancer activity.Formule :C19H18F2N4O2SDegré de pureté :98.82%Couleur et forme :SoildMasse moléculaire :404.43CX-5461
CAS :CX5461 is an orally rRNA synthesis inhibitor that inhibits Pol I-driven rRNA transcription. CX5461 has antitumor activity. Cost-effective and quality-assured.Formule :C27H27N7O2SDegré de pureté :95.44% - 99.25%Couleur et forme :SolidMasse moléculaire :513.61IRE1α kinase-IN-1
CAS :IRE1α kinase-IN-1 is a highly selective IRE1α (ERN1) inhibitor, with an IC50 of 77 nM.Formule :C26H26ClFN8Degré de pureté :99.18%Couleur et forme :SolidMasse moléculaire :504.99Ref: TM-T9564
1mg116,00€5mg283,00€10mg452,00€25mg707,00€50mg1.017,00€100mg1.406,00€1mL*10mM (DMSO)311,00€CRT0044876
CAS :CRT0044876 (7-NO2-ICA) is a potent and selective APE1 inhibitor with IC50 of ~3 μM.Formule :C9H6N2O4Degré de pureté :98.27% - 98.98%Couleur et forme :Brown PowderMasse moléculaire :206.15INCB086550
CAS :INCB086550 (PD-1/PD-L1-IN-8) (example 24) is a PD-1/PD-L1 inhibitor, with an IC50 <= 10 nM.Formule :C41H39N7O4Degré de pureté :98.21%Couleur et forme :SolidMasse moléculaire :693.79Cdc7-IN-1
CAS :Cdc7-IN-1: selective ATP-competitive Cdc7 kinase inhibitor; IC50 0.6 nM at 1mM ATP; induces cancer cell death.Formule :C21H16ClN3O4Couleur et forme :SolidMasse moléculaire :409.82BVDU 5′-Triphosphate
CAS :BVDU 5′-Triphosphate is an antiviral agent labeled with 5′-Triphosphate that specifically targets viral DNA polymerase.Formule :C11H16BrN2O14P3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :573.08Tirofiban hydrochloride monohydrate
CAS :Tirofiban(MK383) hydrochloride monohydrate is a non-peptide glycoprotein IIb/IIIa antagonist. Cost-effective and quality-assured.Formule :C22H39ClN2O6SDegré de pureté :95.83% - 99.94%Couleur et forme :White SolidMasse moléculaire :495.07S-Gem
CAS :S-Gem, a thioredoxin reductase (TrxR)-dependent prodrug of Gemcitabine, is selectively activated by TrxR.Formule :C13H15F2N3O6S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :411.4CBFβ Inhibitor
CAS :CBFβ Inhibitor (5-Ethyl-4-(4-methoxy-phenyl)-thiazol-2-ylamine) is a cell-permeable CBFβ inhibitor and inhibits its association with Runx1.Formule :C12H14N2OSDegré de pureté :96.50%Couleur et forme :SolidMasse moléculaire :234.32Leucettinib-92
CAS :Leucettinib-92 (compound 92) is a kinase inhibitor selective for DYRK/CLK families, displaying IC50 values of 147 nM (CLK1), 39 nM (CLK2), 5.2 nM (CLK4), 0.8 μMFormule :C21H22N4OSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :378.49Poly(A) polymerase
CAS :Poly(A) polymerase enzymatically adds a polyadenosine tail of 20-200 adenine bases to the 3' end of RNA, a process that involves integrating ATP as AMP.Degré de pureté :98%Couleur et forme :Solid5-Fluoroorotic acid
CAS :5-Fluoroorotic acid is an inhibitor of thymidylate synthase.Formule :C5H3FN2O4Degré de pureté :100% - 99.7%Couleur et forme :White To Pale Yellow PowderMasse moléculaire :174.09MU147
CAS :MU147 is an MRE11 nuclease inhibitor and chemical probe with anticancer properties, exhibiting lethal effects on Ehrlich ascites tumor cells both in vivo and in vitro. It disrupts the MRE11 nuclease-dependent double-strand break repair mechanism without impairing ATM activation. Additionally, MU147 damages the degradation of nascent strands at stalled replication forks and selectively affects BRCA2-deficient cells.Formule :C19H13N3O3SCouleur et forme :SolidMasse moléculaire :363.39Deoxythymidine triphosphate
CAS :Deoxythymidine triphosphate (dTTP) is one of the four nucleoside triphosphates that are used in the in vivo synthesis of DNA.Formule :C10H14N2Na3O14P3Degré de pureté :96.00%Couleur et forme :White Amorphous PowderMasse moléculaire :548.11PFM03
CAS :PFM03 is a endonuclease inhibitor that specifically blocks Mre11,reduce MRN endonuclease activity, blocking hMRN-mediated endonucleotomy and nuclear exocytosis.Formule :C14H15NO2S2Degré de pureté :98.20% - 99.98%Couleur et forme :SolidMasse moléculaire :293.4TC-S 7005
CAS :TC-S 7005 is an effective inhibitor of Polo-like kinases (IC50s: 214 nM, 4 nM and 24 nM for Plk1, Plk2, and Plk3).Formule :C21H17N3O3Degré de pureté :99.68%Couleur et forme :SolidMasse moléculaire :359.38Ref: TM-T17008
1mg57,00€2mg84,00€5mg125,00€10mg188,00€25mg354,00€50mg532,00€100mg712,00€500mgÀ demander1mL*10mM (DMSO)138,00€Metarrestin
CAS :Metarrestin (ML246) is a first-in-class perinucleolar compartment inhibitor with a favorable PK profile, which effectively suppresses metastasis.Formule :C31H30N4ODegré de pureté :99.45%Couleur et forme :SolidMasse moléculaire :474.6Ref: TM-T12006
1mg40,00€2mg52,00€5mg88,00€10mg144,00€25mg298,00€50mg512,00€100mg740,00€500mg1.539,00€RG7800 tetrahydrochloride
RG7800 hydrochloride is an orally active modulator of SMN2 splicing, exhibiting EC50 values of 23 nM for SMN2 splicing and 87 nM for SMN protein production.Formule :C24H32Cl4N6ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :562.362'-Deoxy-N4-methylcytidine
CAS :2’-Deoxy-N4-methylcytidine (N(3)-Methyl-2'-deoxycytidine) is a purine nucleoside analog with potential antitumor activity for the study of apoptosis.Formule :C10H15N3O4Degré de pureté :99.61%Couleur et forme :SolidMasse moléculaire :241.24HMN-176
CAS :HMN-176 is a stilbene derivative which inhibits mitosis, interfering with polo-like kinase-1 (plk1).Formule :C20H18N2O4SDegré de pureté :98.92% - 98.99%Couleur et forme :SolidMasse moléculaire :382.43Ref: TM-T3643
1mg43,00€2mg56,00€5mg88,00€10mg119,00€25mg188,00€50mg350,00€100mg522,00€500mg1.130,00€1mL*10mM (DMSO)79,00€SGC-CLK-1
CAS :SGC-CLK-1 is a potent and selective inhibitor of Cdc2-like kinases CLK1, CLK2, and CLK4. It effectively inhibits the growth of melanoma and glioblastoma cells.Formule :C19H15F3N6O2Couleur et forme :SolidMasse moléculaire :416.36APY29
CAS :APY29 is an allosteric modulator of IRE1α; inhibits IRE1α autophosphorylation (IC50 = 280 nM) and activates IRE1α RNase activity.Formule :C17H16N8Degré de pureté :96.51% - 98.46%Couleur et forme :SolidMasse moléculaire :332.36Ref: TM-T3654
2mg43,00€5mg65,00€10mg96,00€25mg177,00€50mg301,00€100mg543,00€500mg1.130,00€1mL*10mM (DMSO)71,00€Budigalimab
CAS :Budigalimab (ABBV 181) is a humanized monoclonal antibody targeting PD-1 with potential antitumor activity.Degré de pureté :95% - 95%Couleur et forme :LiquidHomouridine
CAS :Homouridine, an analogue of uridine, functions as an intermediate in the synthesis of MMP-2 inhibitor (compound I, IC50 = 150 μM).Formule :C10H14N2O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :258.23CDK5-IN-3
CAS :CDK5-IN-3 is a selective and potent CDK5 inhibitor that inhibits CDK5/p25 and CDK2/CycA, and can be used in the study of cancer.Formule :C22H26N4ODegré de pureté :98.21%Couleur et forme :SolidMasse moléculaire :362.47Avelumab
CAS :Avelumab is a fully human IgG1 anti-PD-L1 monoclonal antibody. Avelumab shows potential antibody-dependent cell-mediated cytotoxicity.Degré de pureté :95% - 98.3% (SEC-HPLC)Couleur et forme :LiquidMasse moléculaire :143.8 kDaDatelliptium chloride
CAS :Datelliptium chloride is a DNA-intercalating agent derived from ellipticine. Datelliptium chloride shows anti-tumor activities.Formule :C23H28ClN3ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :397.94CK7
CAS :CK7, a Cdk2/9 inhibitor, is instrumental in the synthesis of Nek1 inhibitors BSc5231 and BSc5367.Formule :C14H12N6O2SDegré de pureté :98.07%Couleur et forme :SolidMasse moléculaire :328.35Ref: TM-T9615
1mg52,00€5mg120,00€10mg187,00€25mg376,00€50mg588,00€100mg905,00€200mg1.216,00€1mL*10mM (DMSO)139,00€Barasertib
CAS :AZD1152 is a pro-drug of Barasertib (AZD1152)-hQPA. Which is a highly selective Aurora B inhibitor with IC50 of 0.37 nM in a cell-free assay.Formule :C26H31FN7O6PDegré de pureté :99.63%Couleur et forme :SolidMasse moléculaire :587.54Simurosertib
CAS :Simurosertib (TAK-931) is a selective and ATP-competitive cell division cycle 7 kinase inhibitor (IC50: <0.3 nM).Formule :C17H19N5OSDegré de pureté :99.82% - 99.93%Couleur et forme :SolidMasse moléculaire :341.43Ref: TM-T12642L
1mg74,00€2mg96,00€5mg180,00€10mg250,00€25mg465,00€50mg677,00€100mg938,00€1mL*10mM (DMSO)187,00€Acrixolimab
CAS :Acrixolimab is a humanized IgG4-κ monoclonal antibody that selectively targets PD-1 [1] [2].Degré de pureté :98%Couleur et forme :Liquid6-Thioinosine
CAS :6-Thioinosine (6TI) is a purine antimetabolite, acts as an anti-adipogenesis agent.Formule :C10H12N4O4SDegré de pureté :97.74%Couleur et forme :SolidMasse moléculaire :284.29Ref: TM-T7621
2mg51,00€5mg85,00€10mg119,00€25mg150,00€50mg188,00€100mg283,00€200mg432,00€1mL*10mM (DMSO)99,00€Natalizumab
CAS :Natalizumab used for the treatment of relapsing remitting multiple sclerosis and Crohn's disease.Degré de pureté :98.00%Couleur et forme :LiquidMasse moléculaire :N/AKJ Pyr 9
CAS :KJ Pyr 9 is an MYC inhibitor (Kd: 6.5 nM in vitro assay).Formule :C22H15N3O4Degré de pureté :98.07% - ≥98%Couleur et forme :SolidMasse moléculaire :385.37Ref: TM-T15665
2mg39,00€5mg57,00€10mg81,00€25mg145,00€50mg279,00€100mg510,00€200mg683,00€500mg1.064,00€1mL*10mM (DMSO)63,00€DNA Gyrase-IN-9
DNA Gyrase-IN-9 (compound 4j), an antibacterial agent, selectively targets DNA gyrase.Formule :C26H18ClN3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :439.89IXA6
CAS :IXA6 is an IRE1/XBP1s agonist with potential vasoprotective activity for the study of neurodegenerative diseases such as Parkinson's disease.Formule :C22H20ClN3O3SDegré de pureté :98.63%Couleur et forme :SolidMasse moléculaire :441.93CW-069
CAS :CW-069 (IC50=75 μM), an allosteric selective inhibitor of microtubule motor protein HSET, exhibits remarkable specificity over KSP.Formule :C23H21IN2O3Degré de pureté :97.52% - 98.59%Couleur et forme :SolidMasse moléculaire :500.33Ref: TM-T6209
1mg43,00€5mg90,00€10mg125,00€25mg216,00€50mg306,00€100mg432,00€500mg938,00€1mL*10mM (DMSO)89,00€DNA Gyrase-IN-8
CAS :DNA Gyrase-IN-8 is a potent inhibitor of DNA gyrase, demonstrating antimicrobial activity with an IC50 of 8.45 µM [1].Formule :C19H14BrN5ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :408.25Cdc7-IN-7
CAS :Cdc7-IN-7 is a potent inhibitor of Cdc7 kinase.Formule :C21H22N4O5Degré de pureté :99.25%Couleur et forme :SolidMasse moléculaire :410.42ZIM
CAS :ZIM, from 4-Aminoantipyrine, induces DNA and chromosomal damage, cell death, and phagocytosis, with potential in cancer therapy.Formule :C20H19N3O3Degré de pureté :99.13%Couleur et forme :SolidMasse moléculaire :349.38Ref: TM-T72024
5mg39,00€10mg58,00€25mg105,00€50mg170,00€100mg271,00€200mg398,00€1mL*10mM (DMSO)52,00€Pyrintegrin
CAS :Pyrintegrin: β1-integrin agonist, boosts embryonic stem cell survival, and podocyte protection, improves cell-matrix adhesion.Formule :C23H25N5O3SDegré de pureté :97.81%Couleur et forme :SolidMasse moléculaire :451.54Ref: TM-T16695
1mg82,00€2mg96,00€5mg159,00€10mg226,00€25mg435,00€50mg648,00€100mg924,00€200mg1.225,00€1mL*10mM (DMSO)168,00€Senexin B
CAS :Senexin B is a potent and selective inhibitor of CDK8/19(CDK8 and CDK19 with Kds of 140 nM and 80 nM).Formule :C27H26N6ODegré de pureté :99.67%Couleur et forme :SolidMasse moléculaire :450.53Ref: TM-T8430
1mg97,00€2mg131,00€5mg188,00€10mg305,00€25mg487,00€50mg655,00€100mg905,00€1mL*10mM (DMSO)215,00€GDC-0575
CAS :GDC-0575 (ARRY-575) is a highly-selective oral small-molecule Chk1 inhibitor(IC50 of 1.2 nM).Formule :C16H20BrN5ODegré de pureté :≥95%Couleur et forme :SolidMasse moléculaire :378.27CCT-251921
CAS :CCT-251921 is a potent, selective, and orally bioavailable CDK8 inhibitor (IC50: 2.3 nM).Formule :C21H23ClN6ODegré de pureté :97.74%Couleur et forme :SolidMasse moléculaire :410.9Ref: TM-T14901
1mg95,00€5mg221,00€10mg324,00€25mg548,00€50mg785,00€100mg1.074,00€1mL*10mM (DMSO)202,00€PROTAC CDK9/CycT1 Degrader-2
PROTAC CDK9/CycT1 Degrader-2 inhibits CDK9 with an IC50 of 45 nM [1].Formule :C30H36N4O6S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :612.76BMS-1001 hydrochloride
CAS :BMS-1001 hydrochloride is an orally active inhibitor of human PD-1/PD-L1 immune checkpoint with low-toxicity in cells.BMS-1001 alleviates the inhibitory effectFormule :C35H35ClN2O7Degré de pureté :97.36%Couleur et forme :SolidMasse moléculaire :631.11Ref: TM-T10565
1mg56,00€5mg127,00€10mg197,00€25mg401,00€50mg645,00€100mg1.026,00€200mg1.378,00€1mL*10mM (DMSO)172,00€ZCL278
CAS :ZCL278 is a selective Cdc42 GTPase inhibitor.Formule :C21H19BrClN5O4S2Degré de pureté :96.29% - 99.72%Couleur et forme :SolidMasse moléculaire :584.89Ref: TM-T1855
5mg50,00€10mg79,00€25mg136,00€50mg221,00€100mg310,00€200mg497,00€500mg805,00€1mL*10mM (DMSO)79,00€CID 5951923
CAS :CID 5951923 is an inhibitor of KLF5 transcription factor with an IC50 of 603 nM.Formule :C16H18N2O7SDegré de pureté :100.00%Couleur et forme :SolidMasse moléculaire :382.39Barasertib-HQPA
CAS :Barasertib-HQPA (AZD2811) is a highly selective Aurora B inhibitor (IC50: 0.37 nM) and demonstrates ~3,700-fold greater selectivity than Aurora A.Formule :C26H30FN7O3Degré de pureté :98.43% - 99.29%Couleur et forme :SolidMasse moléculaire :507.56TH588
CAS :TH588 is nudix hydrolase family inhibitor that effectively and selectively engages and inhibits the MTH1(IC50: 5 nM) in cells.Formule :C13H12Cl2N4Degré de pureté :96.05% - 99.82%Couleur et forme :SolidMasse moléculaire :295.17AAPK-25
CAS :AAPK-25, a dual Aurora/PLK inhibitor, disrupts mitosis, induces apoptosis, and has antitumor properties.Formule :C21H13Cl2N3O2SDegré de pureté :97.79%Couleur et forme :SolidMasse moléculaire :442.32Ref: TM-T10215
1mg95,00€5mg202,00€10mg303,00€25mg550,00€50mg825,00€100mg1.198,00€1mL*10mM (DMSO)233,00€Palbociclib monohydrochloride
CAS :Palbociclib monohydrochloride (PD 0332991 hydrochloride) is a selective inhibitor of CDK4/6, with no inhibition against a panel of 36 additional protein kinasesFormule :C24H29N7O2·HClDegré de pureté :100% - 99.91%Couleur et forme :SolidMasse moléculaire :483.99JSH-150
CAS :JSH-150 is a highly selective CDK9 inhibitor(IC50 : 1 nM).Formule :C24H33ClN6O2SDegré de pureté :100% - 99.96%Couleur et forme :SolidMasse moléculaire :505.08LIMK-IN-22j
CAS :LIMK-IN-22j (LIMK inhibitor 22j) is an effective and selective inhibitor of LIMK.Formule :C20H21BrN8Degré de pureté :99.17%Couleur et forme :SolidMasse moléculaire :453.34Cilengitide
CAS :Cilengitide (EMD 121974) is a potent integrin inhibitor for the αvβ3/5 receptor (IC50: 4.1/79 nM, in cell-free assays); ~10-fold selectivity against gpIIbIIIa.Formule :C27H40N8O7Degré de pureté :98% - 99.8%Couleur et forme :SolidMasse moléculaire :588.66Ref: TM-T2494
1mg49,00€2mg70,00€5mg96,00€10mg160,00€25mg274,00€50mg439,00€100mg632,00€1mL*10mM (DMSO)137,00€Mirvetuximab
CAS :Mirvetuximab, a monoclonal antibody targeting FOLR1/FRα, treats ovarian and FRα-positive cancers, often paired with platinum-based drugs.Degré de pureté :> 95% - > 95%Couleur et forme :LiquidMasse moléculaire :148 kDa (average)Ispinesib
CAS :Ispinesib (SB-715992), a selective, effectvie and reversible inhibitor of kinesin spindle protein (KSP), is derived from quinazolinone, with antineoplasticFormule :C30H33ClN4O2Degré de pureté :98% - 98.59%Couleur et forme :SolidMasse moléculaire :517.06Ref: TM-T2103
1mg39,00€2mg50,00€5mg79,00€10mg118,00€25mg210,00€50mg339,00€100mg557,00€500mg1.216,00€1mL*10mM (DMSO)89,00€CDK8/19-IN-1
CAS :CDK8/19-IN-1 is a selective and oral bioavailable CDK8/19 dual inhibitor (IC50s: 0.46 nM, 0.99 nM, and 270 nM for CDK8, CDK19, and CDK9).Formule :C19H18N4O4S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :430.5Werner syndrome RecQ helicase-IN-1
CAS :Werner syndrome RecQ helicase-IN-1 is a potent Werne r syndrome RecQ DNA deconjugase (WRN) inhibitor that can be used to study cancers such as colon and stomachFormule :C31H31ClF3N9O5Degré de pureté :98.74% - 99.62%Couleur et forme :SolidMasse moléculaire :702.08Ref: TM-T72107
1mg60,00€5mg125,00€10mg177,00€25mg296,00€50mg502,00€100mg803,00€500mg1.795,00€1mL*10mM (DMSO)822,00€CDK12-IN-E9
CAS :CDK12-IN-E9 is a potent and selective covalent CDK12 inhibitor and non-covalent CDK9 inhibitor while avoiding ABC transporter-mediated efflux.Formule :C24H30N6O2Couleur et forme :SolidMasse moléculaire :434.53Folinic Acid Calcium Salt Pentahydrate
CAS :Folinic Acid Calcium Salt Pentahydrate (Leucovorin Calcium Pentahydrate), a reduced folic acid, is used in combination with other chemotherapeutics.Formule :C20H21CaN7O7·5H2ODegré de pureté :100% - 99.17%Couleur et forme :Yellowish-White To Yellow PowderMasse moléculaire :601.58NITD-2
CAS :NITD-2 is a DENV RdRp inhibitor with poor cell membrane penetration; no vaccine or antiviral for DENV exists.Formule :C23H19N3O4SDegré de pureté :98.03% - 99.46%Couleur et forme :SolidMasse moléculaire :433.48Ref: TM-T8886
1mg74,00€5mg170,00€10mg274,00€25mg472,00€50mg655,00€100mg944,00€200mg1.264,00€1mL*10mM (DMSO)188,00€GP-82996
CAS :GP-82996 (CINK4) inhibits CDK4/6; IC50s: 1.5 μM (CDK4/D1), 5.6 μM (CDK6/D1), 25 μM (Cdk5/p35); triggers U2OS cancer cell apoptosis.Formule :C27H32N6ODegré de pureté :99.57%Couleur et forme :SolidMasse moléculaire :456.58N6,N6-Dimethyladenosine
CAS :N6,N6-Dimethyladenosine is find in mycobacterium bovis Bacille Calmette-Guérin tRNA.Formule :C12H17N5O4Degré de pureté :98.79%Couleur et forme :White PowderMasse moléculaire :295.29Aurora kinase inhibitor-3
CAS :Aurora kinase inhibitor-3 (Aurora Kinase Inhibitor III) is a potent inhibitor of Aurora A kinase (IC50 = 42 nM).1 It is selective for Aurora A over BMX, BTK,Formule :C21H18F3N5ODegré de pureté :98.91%Couleur et forme :SolidMasse moléculaire :413.4Ref: TM-T5524
1mg78,00€2mg97,00€5mg188,00€10mg298,00€25mg500,00€50mg710,00€100mg938,00€200mg1.311,00€1mL*10mM (DMSO)215,00€HDAC-IN-85
HDAC-IN-85 (Compound 1) is an HDAC inhibitor capable of crossing the blood-brain barrier. It exhibits inhibitory effects on brain tumor cell lines and can induce acetylation, resulting in DNA double-strand breaks and promoting RAD51 ubiquitination, which disrupts the DNA repair process. HDAC-IN-85 is applicable in studies of glioblastoma.Formule :C24H27FN4O5Couleur et forme :SolidMasse moléculaire :470.49RG7800
CAS :RG7800 (RO6885247) has the potential for spinal muscular atrophy treatment. RG7800 is an SMN2 splicing modifier.Formule :C24H28N6ODegré de pureté :99.44%Couleur et forme :SolidMasse moléculaire :416.52ART558
CAS :ART558 is a potent, selective, low molecular weight, allosteric DNA polymerase activity of Polθ inhibitor (IC50=7.9 nM).Formule :C21H21F3N4O2Degré de pureté :99.18%Couleur et forme :SolidMasse moléculaire :418.41PD-1/PD-L1-IN-NP19
CAS :PD-1/PD-L1-IN-NP19: a PD-1/PD-L1 inhibitor with 12.5 nM IC50, may boost antitumor immunity.Formule :C33H31ClN2O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :555.06Doxifluridine
CAS :Doxifluridine (AMC 0101) is a fluoropyrimidine derivative and oral prodrug of the antineoplastic agent 5-fluorouracil (5-FU) with antitumor activity.Formule :C9H11FN2O5Degré de pureté :99.47% - 99.86%Couleur et forme :White SolidMasse moléculaire :246.192′-Deoxy-2′-fluoroguanosine
CAS :2′-Deoxy-2′-fluoroguanosine is a nucleoside analog that potently inhibits influenza virus A and B strains(EC90 <0.35 μM).Formule :C10H12FN5O4Degré de pureté :99.82%Couleur et forme :SolidMasse moléculaire :285.23Raltitrexed
CAS :Raltitrexed (D1694)(IC50 of 9 nM), a thymidylate synthase inhibitor, is used for the inhibition of L1210 cell growth.Formule :C21H22N4O6SDegré de pureté :98.99% - 99.06%Couleur et forme :Yellow Crystalline PowderMasse moléculaire :458.49SCH-1473759
CAS :SCH-1473759 is an inhibitor of the aurora (IC50s: 4 and 13 nM for Aurora A and B, respectively).Formule :C20H26N8OSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :426.54Cucurbitacin B
CAS :Cucurbitacin B (Cuc B) has profound in vitro and in vivo antiproliferative effects against human pancreatic Y cells.Formule :C32H46O8Degré de pureté :97.10% - 99.33%Couleur et forme :SolidMasse moléculaire :558.7AZD-5597
CAS :AZD-5597 ((S)-(4-((5-Fluoro-4-(1-isopropyl-2-methyl-1H-imidazol-5-yl)pyrimidin-2-yl)amino)phenyl)(3-(methylamino)pyrrolidin-1-yl)methanone) is a potentFormule :C23H28FN7ODegré de pureté :98.01%Couleur et forme :SolidMasse moléculaire :437.51Ref: TM-T21544
1mg57,00€5mg120,00€10mg187,00€25mg416,00€50mg655,00€100mg924,00€1mL*10mM (DMSO)144,00€Sapacitabine
CAS :Sapacitabine (CS682) is a nucleoside analog precursor with anticancer activity used in the study of leukemia.Formule :C26H42N4O5Degré de pureté :98.82%Couleur et forme :SolidMasse moléculaire :490.64T4 RNA ligase
T4 RNA ligase is an enzyme that facilitates the ligation of single-stranded DNA.Degré de pureté :98%Couleur et forme :Odour SolidMonastrol
CAS :Monastrol ((±)-Monastrol) is a potent and cell-permeable inhibitor of the mitotic kinesin Eg5.Formule :C14H16N2O3SDegré de pureté :98.59% - 99.19%Couleur et forme :SolidMasse moléculaire :292.35Ref: TM-T4048
1mg48,00€5mg78,00€10mg97,00€25mg188,00€50mg311,00€100mg502,00€500mg1.074,00€1mL*10mM (DMSO)87,00€Enrofloxacin
CAS :Enrofloxacin (BAY-Vp2674) is a veterinary antibacterial agent, used in poultry.Formule :C19H22FN3O3Degré de pureté :100% - 99.89%Couleur et forme :Pale Yellow CrystalsMasse moléculaire :359.39PF-06873600
CAS :PF-06873600: oral CDK inhibitor (CDK2/4/6), Ki 0.09-0.16 nM, potential anticancer drug.Formule :C20H27F2N5O4SDegré de pureté :98.77% - 99.58%Couleur et forme :SolidMasse moléculaire :471.52Ref: TM-T8463
1mg57,00€5mg120,00€10mg188,00€25mg354,00€50mg588,00€100mg938,00€200mg1.264,00€1mL*10mM (DMSO)131,00€Zimberelimab
CAS :Zimberelimab (GLS-010) is a humanized antibody targeting PD-1, with anticancer activity.Degré de pureté :95%Couleur et forme :Liquid7-Methylguanosine
CAS :7-Methylguanosine is a novel cNIIIB nucleotidase inhibitor (IC50 : 87.8 ± 7.5 μM).Formule :C11H16N5O5Degré de pureté :98.11%Couleur et forme :SolidMasse moléculaire :298.282′-O-Methylcytidine
CAS :2′-O-Methylcytidine inhibits NS5B-catalyzed RNA synthesis in vitro, in a manner that is competitive with substrate nucleoside triphosphate.Formule :C10H15N3O5Degré de pureté :99.81%Couleur et forme :SolidMasse moléculaire :257.24Ilorasertib hydrochloride
CAS :Ilorasertib hydrochloride (ABT-348 hydrochloride) is an ATP-competitive multitargeted kinase inhibitor, which inhibits Aurora C, Aurora B, and Aurora A (IC50s:Formule :C25H22ClFN6O2SDegré de pureté :98.34%Couleur et forme :SolidMasse moléculaire :525TK216
CAS :TK216 is a potent inhibitor of E26 transformation-specific (ETS) with anticancer activity.Formule :C19H15Cl2NO3Degré de pureté :97.22%Couleur et forme :SolidMasse moléculaire :376.23(S)-Monastrol
CAS :Monastrol is a potent and cell-permeable inhibitor of the mitotic kinesin Eg5.Formule :C14H16N2O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :292.356-Mercaptopurine
CAS :6-Mercaptopurine (6-MP) is an antimetabolite antineoplastic agent with immunosuppressant properties.Formule :C5H4N4SDegré de pureté :99.53% - 99.63%Couleur et forme :Yellow Crystalline Powder SolidMasse moléculaire :152.18KIF18A-IN-15
CAS :KIF18A-IN-15 (Compound Example 36) is a KIF18A inhibitor, available in two forms, EX36-A and its enantiomer EX36-B, both with an IC50 range of 0.01-0.1 μM. These compounds inhibit the viability of OVCAR-3 cells, with IC50 values of 0.01-0.1 μM for EX36-A and 0-0.01 μM for EX36-B. KIF18A-IN-15 is applicable in research on tumors, including colon, breast, and lung cancers.Formule :C25H33F3N6O5SCouleur et forme :SolidMasse moléculaire :586.63Voruciclib hydrochloride
CAS :Voruciclib hydrochloride is an orally active and selective inhibitor of CDK (Ki: 0.626 nM-9.1 nM).Formule :C22H20Cl2F3NO5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :506.33-Methylcytidine
CAS :3-Methylcytidine as biomarkers of four different types of cancer: lung cancer, gastric cancer, colon cancer, and breast cancer.Formule :C10H15N3O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :257.24Kif15-IN-2
CAS :Kif15-IN-2 is a kinesin Kif15 inhibitor with potential anticancer activity and can be used in prostate cancer research.Formule :C20H20N6O4SDegré de pureté :98.17%Couleur et forme :SolidMasse moléculaire :440.48CDK1-IN-2
CAS :CDK1-IN-2 (cdk1 inhibitor 2) is a CDK1 inhibitor with IC50 of 5.8 μM.Formule :C17H11ClN2ODegré de pureté :98.41%Couleur et forme :SoildMasse moléculaire :294.73Ref: TM-T64373
1mg50,00€5mg107,00€10mg170,00€25mg354,00€50mg567,00€100mg810,00€500mg1.644,00€1mL*10mM (DMSO)103,00€NU6140
CAS :NU6140 is a selective inhibitor of CDK2-cyclin A (IC50, 0.41 μM).Formule :C23H30N6O2Degré de pureté :98.33%Couleur et forme :SolidMasse moléculaire :422.52Ref: TM-T16359
2mg42,00€5mg64,00€10mg97,00€25mg187,00€50mg301,00€100mg437,00€200mg612,00€1mL*10mM (DMSO)71,00€Bisindolylmaleimide X hydrochloride
CAS :Bisindolylmaleimide X hydrochloride (BIM-X hydrochloride) is a potent and selective PKC inhibitor. It is also a potent CDK2 antagonist (IC50: 200 nM).Formule :C26H25ClN4O2Degré de pureté :98.5%Couleur et forme :SolidMasse moléculaire :460.96