
Cycle cellulaire/point de contrôle
Les inhibiteurs du cycle cellulaire/des points de contrôle sont des composés qui perturbent la progression normale du cycle cellulaire, en particulier aux points de contrôle régulateurs clés. Ces inhibiteurs sont cruciaux pour étudier la division cellulaire, comprendre la prolifération des cellules cancéreuses et développer des thérapies anticancéreuses. En ciblant des phases spécifiques du cycle cellulaire, ces inhibiteurs peuvent induire un arrêt du cycle cellulaire, conduisant à l'apoptose ou à la sénescence des cellules à division rapide. Chez CymitQuimica, nous offrons une large gamme d'inhibiteurs de haute qualité du cycle cellulaire/des points de contrôle pour soutenir vos recherches en biologie du cancer, biologie cellulaire et développement de médicaments.
Sous-catégories appartenant à la catégorie "Cycle cellulaire/point de contrôle"
- Aurora Kinase
- CDK
- Arrêt du cycle cellulaire
- Chk
- c-Myc
- Dynamine
- DYRK
- Ferroptose
- HSP
- Intégrine
- Kinésine
- KSP
- LIM Kinase
- Microtubules associés
- PKC
- PLK
- Rho
- ROCK
- Wee1
Affichez 11 plus de sous-catégories
Produits appartenant à la catégorie "Cycle cellulaire/point de contrôle"
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TY-011
CAS :TY-011 is an inhibitor of Aurora A/B kinases. This compound induces DNA damage and cell apoptosis (Apoptosis) in human gastric cancer cells by promoting abnormal microtubule-kinetochore attachments, effectively suppressing cancer cell proliferation. The IC50 values for TY-011 in human gastric cancer cell lines range from 0.11-4.49 μM. It is utilized in research focused on gastric cancer.Formule :C18H16ClN5Couleur et forme :SolidMasse moléculaire :337.81T025
CAS :T025 inhibits CLK1-4 (Kds: 0.074-6.5 nM), shows anti-cancer effects (IC50: 30-300 nM), useful for MYC-related disease research.Formule :C21H18N8Degré de pureté :98.08%Couleur et forme :SolidMasse moléculaire :382.42Ref: TM-T13058
1mg143,00€5mg354,00€10mg528,00€25mg852,00€50mg1.159,00€100mg1.568,00€500mg3.125,00€1mL*10mM (DMSO)378,00€Empesertib
CAS :Empesertib (BAY 1161909) is an orally bioavailable and selective inhibitor Mps1(IC50 < 1 nM), with potential antineoplastic activity.Formule :C29H26FN5O4SDegré de pureté :97.45% - 98.44%Couleur et forme :SolidMasse moléculaire :559.61Ref: TM-T8487
1mg90,00€5mg183,00€10mg275,00€25mg449,00€50mg615,00€100mg848,00€200mg1.121,00€1mL*10mM (DMSO)245,00€CDK2 degrader 4
CAS :CDK2 degrader4 (compound 104) is a potent degrader of CDK2, showing promise for cancer research applications.Formule :C23H26ClN3O5Couleur et forme :SolidMasse moléculaire :459.923Adebrelimab
CAS :Adebrelimab (SHR-1316) is a humanized monoclonal antibody targeting PD-L1 with antitumor activity for the study of solid tumors.Degré de pureté :95% - 95%Couleur et forme :LiquidCHK1-IN-4 hydrochloride
CHK1-IN-4 hydrochloride is a potent inhibitor of checkpoint kinase 1 (chk1).Formule :C18H19BrClN7O2Degré de pureté :98.02%Couleur et forme :SoildMasse moléculaire :480.75BT100
BT100, an aptamer, impedes the interaction of von Willebrand factor (VWF) with platelet glycoprotein GPIb, thus obstructing arterial thrombosis [1].Degré de pureté :98%Couleur et forme :Odour Solid2'-Amino-2'-deoxy-b-D-arabino-5-methyl uridine
CAS :2'-Amino-2'-deoxy-b-D-arabino-5-methyl uridine is a purine nucleoside analog with potential antitumor activity.Formule :C10H15N3O5Degré de pureté :96.76%Couleur et forme :SolidMasse moléculaire :257.24AT9283
CAS :AT9283 (J-504568) is an effective multi-targeted inhibitor of JAK2(IC50=1.2 nM) and JAK3(IC50=1.1 nM), Aurora A, Aurora B and Abl(T315I).Formule :C19H23N7O2Degré de pureté :99.83% - 99.98%Couleur et forme :SolidMasse moléculaire :381.43Ref: TM-T3068
1mg47,00€2mg60,00€5mg95,00€10mg170,00€25mg299,00€50mg499,00€100mg723,00€1mL*10mM (DMSO)97,00€CCT241736
CAS :CCT241736 is an orally bioavailable dual FLT3/Aurora kinase inhibitor that also inhibits clinically relevant FLT3-resistant mutants including FLT3-ITD and FLT3Formule :C22H23Cl2N7Degré de pureté :96.2% - 99.88%Couleur et forme :SolidMasse moléculaire :456.37Cdk1/2 Inhibitor III
CAS :Cdk1/2 Inhibitor III is a selective Cdk1/2 inhibitor with an IC50 value of 2.1 μM against CDK1/cyclin B.Formule :C15H13F2N7O2S2Degré de pureté :100%Couleur et forme :SolidMasse moléculaire :425.44Ref: TM-T14914
1mg333,00€5mg787,00€10mg1.074,00€25mg1.510,00€50mg1.882,00€100mg2.375,00€500mg4.655,00€CRT-0105950
CAS :CRT-0105950 is an effective LIMK inhibitor that acts by suppressing cofilin phosphorylation and increasing αTubulin acetylation in cells.Formule :C21H16ClN3OSDegré de pureté :99.78% - 99.86%Couleur et forme :SolidMasse moléculaire :393.89Ref: TM-T23917
1mg65,00€5mg140,00€10mg216,00€25mg439,00€50mg707,00€100mg1.130,00€1mL*10mM (DMSO)156,00€IRE1α kinase-IN-9
CAS :IRE1α kinase-IN-9 (compound 2) is a potent inhibitor of IRE-1α, demonstrating an average IC50 value of less than 0.1 μM.Formule :C24H24N2O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :436.46Isoguanine
CAS :Isoguanine is a purine base that is an isomer of guanine. A building block in organic synthesis.Formule :C5H5N5ODegré de pureté :99.90%Couleur et forme :SolidMasse moléculaire :151.13Vidarabine
CAS :Vidarabine is a nucleoside antibiotic from Streptomyces with antiviral properties, effective against herpes and other DNA viruses.Formule :C10H13N5O4Degré de pureté :100%Couleur et forme :White To Off-White Crystalline PowderMasse moléculaire :267.24Rac1 Inhibitor F56, control peptide acetate
Rac1 Inhibitor F56, control peptide acetate is a control peptide version of Rac1 Inhibitor; comprises residues 45-60 of Rac1 with Trp56 replaced by Phe.Formule :C74H120N18O25SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :1692.94Lon-TK
Lon-TK is a glycolysis inhibitor of LTB, linked with a linker conjugate. LTB is an intelligent responsive prodrug, comprised of Lonidamine (Lon) and a PD-L1 inhibitor (BMS-1), which are connected through a thioketal linkage. It effectively inhibits glycolytic metabolism in tumor cells and blocks the PD-1/PD-L1 immune escape pathway. Lon-TK holds potential for use in photodynamic-enhanced immunotherapy research.Formule :C24H28Cl2N2O3S2Couleur et forme :SolidMasse moléculaire :527.53rel-(2S,3R)-Voruciclib hydrochloride
CAS :Rel-(2S,3R)-Voruciclib hydrochloride is an enantiomer of Voruciclib hydrochloride, an orally active cyclin-dependent kinase (CDK) inhibitor.Formule :C22H20Cl2F3NO5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :506.3CVT-313
CAS :CVT-313 (NG-26) is a potent, selective, reversible, and ATP-competitive inhibitor.Formule :C20H28N6O3Degré de pureté :97.46% - 97.97%Couleur et forme :SolidMasse moléculaire :400.47Ref: TM-T3195
1mg44,00€2mg55,00€5mg88,00€10mg118,00€25mg208,00€50mg380,00€100mg565,00€1mL*10mM (DMSO)88,00€Prolgolimab
CAS :Prolgolimab (BCD-100) is an anti-PD-1 antibody used in melanoma research.Degré de pureté :>95%Couleur et forme :Liquid6-O-Methyl Guanosine
CAS :6-O-Methyl Guanosine inhibit colony-forming ability in a malignant xeroderma pigmentosum cell line.Formule :C11H15N5O5Degré de pureté :97.50%Couleur et forme :SolidMasse moléculaire :297.27Lysidine
CAS :Lysidine (2-Methyl-2-iMidazoline) is a nucleoside rarely seen outside of tRNA. Lysidine has better translation fidelity.Formule :C4H8N2Degré de pureté :98%Couleur et forme :Light Yellow To Off-White CrystallineMasse moléculaire :84.12Trifluridine
CAS :Trifluridine is a fluorinated thymidine analog with antineoplastic and antiviral properties, disrupting DNA and protein synthesis, leading to apoptosis.Formule :C10H11F3N2O5Degré de pureté :99.39% - 99.82%Couleur et forme :White Crystalline PowderMasse moléculaire :296.2Haspin-IN-3
CAS :Haspin-IN-3 is a potent haspin inhibitor with an IC50 of 14 nM.Haspin-IN-3 has anticancer activity.Formule :C16H10N2O3Degré de pureté :98.78%Couleur et forme :SolidMasse moléculaire :278.261-Methylcytosine
CAS :1-Methylcytosine (4-amino-1-methylpyrimidin-2(1H)-one) is a methylated form of the cytosine and can be used as the nucleobase of hachimoji DNA paired withFormule :C5H7N3ODegré de pureté :100%Couleur et forme :SolidMasse moléculaire :125.13MM41
CAS :MM41 is a human telomeric and gene promoter DNA quadruplex stabilizer with an IC50 of <10 nM against the MIA PaCa-2 pancreatic cancer cell line.Formule :C44H66N10O6Degré de pureté :97.13%Couleur et forme :SolidMasse moléculaire :831.06Ref: TM-T60028
1mg52,00€5mg116,00€10mg178,00€25mg293,00€50mg393,00€100mg520,00€200mg712,00€1mL*10mM (DMSO)160,00€Kira8
CAS :Kira8 (AMG-18) is a mono-selective IRE1α inhibitor that allosterically attenuates IRE1α RNase activity (IC50: 5.9 nM).Formule :C31H29ClN6O3SDegré de pureté :98.07%Couleur et forme :SolidMasse moléculaire :601.12Ref: TM-T11762L
1mg87,00€5mg202,00€10mg305,00€25mg567,00€50mg810,00€100mg1.111,00€1mL*10mM (DMSO)269,00€SCH-1473759 hydrochloride
CAS :SCH-1473759 hydrochloride is an inhibitor of aurora(aurora A and B with IC50s of 4 and 13 nM, respectively).Formule :C20H27ClN8OSDegré de pureté :98.29%Couleur et forme :SolidMasse moléculaire :463Didox
CAS :Didox (NSC-324360), a synthetic RR inhibitor, lowers oxidative injury markers in HIV-related dementia.Formule :C7H7NO4Degré de pureté :96.85%Couleur et forme :SolidMasse moléculaire :169.13DMTr-LNA-5MeU-3-CED-phosphoramidite
CAS :DMTr-LNA-5MeU-3-CED-phosphoramidite is a derivative of nucleoside.Formule :C41H49N4O9PDegré de pureté :98.28%Couleur et forme :SolidMasse moléculaire :772.82HMN-214
CAS :HMN-214 (IVX-214) is a potent PLK1 inhibitor with an average IC50 of 0.12 μM.Formule :C22H20N2O5SDegré de pureté :100% - 98.63%Couleur et forme :SolidMasse moléculaire :424.47Ref: TM-T2438
1mg40,00€2mg52,00€5mg85,00€10mg124,00€25mg219,00€50mg350,00€100mg505,00€500mg1.121,00€1mL*10mM (DMSO)92,00€Durvalumab
CAS :Durvalumab is a humanized antibody for cancer, inhibiting PD-L1/PD-1 and CD80 interactions at very low concentrations.Degré de pureté :SDS-PAGE:97.2%;SEC-HPLC:95.3%Couleur et forme :LiquidMasse moléculaire :146.03 kDaILK-IN-2
CAS :ILK-IN-2 (OSU-T315) is a novel potent, orally active ILK (integrin-linked kinase) inhibitor with IC50 of 0.6 μM.Formule :C30H30F3N5ODegré de pureté :99.30%Couleur et forme :SolidMasse moléculaire :533.59Ref: TM-T5488
1mg48,00€5mg97,00€10mg128,00€25mg162,00€50mg192,00€100mg281,00€200mg408,00€1mL*10mM (DMSO)137,00€Tibremciclib
CAS :Tibremciclib is a cyclin-dependent kinase 4 (CDK4) inhibitor that exhibits antineoplastic properties [1].Formule :C28H32F2N8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :518.6MLS-573151
CAS :MLS-573151 is a selective inhibitor of GTPase Cdc42(EC50 of 2 μM).Formule :C21H19N3O2SDegré de pureté :98.80%Couleur et forme :SolidMasse moléculaire :377.46Ref: TM-T22106
2mg35,00€5mg52,00€10mg90,00€25mg170,00€50mg259,00€100mg383,00€200mg545,00€1mL*10mM (DMSO)58,00€DTP3
CAS :DTP3 is a selective MKK7/GADD45β inhibitor, which inhibits cancer-selective NF-κB survival pathway.Formule :C26H35N7O5Couleur et forme :SolidMasse moléculaire :525.6BI-847325
CAS :BI-847325 is a selective dual inhibitor of MEK and aurora kinases (AK) with IC50 values of 4 and 15 nM for human MEK2 and AK-C, respectively.Formule :C29H28N4O2Degré de pureté :97.13% - 97.54%Couleur et forme :SolidMasse moléculaire :464.56Ref: TM-T6785
1mg49,00€5mg97,00€10mg153,00€25mg296,00€50mg445,00€100mg660,00€200mg917,00€1mL*10mM (DMSO)97,00€CASIN
CAS :CASIN (Pirl1-related Compound 2) is a specific inhibitor of GTPase Cdc42 (IC50: 2 uM).Formule :C20H22N2ODegré de pureté :100% - 99.86%Couleur et forme :SolidMasse moléculaire :306.4Ref: TM-T3971
1mg38,00€2mg49,00€5mg74,00€10mg120,00€25mg188,00€50mg283,00€100mg435,00€500mg938,00€1mL*10mM (DMSO)74,00€Kaempferitrin
CAS :Kaempferitrin has antidepressant effects via 5-HT1A, targets HeLa cells, promotes glucose control, and boosts immune function, including NK cells.Formule :C27H30O14Degré de pureté :98% - 99.59%Couleur et forme :SolidMasse moléculaire :578.52Ref: TM-T3386
1mg50,00€5mg123,00€10mg207,00€25mg349,00€50mg515,00€100mg735,00€500mg1.483,00€1mL*10mM (DMSO)156,00€Nolatrexed
CAS :Nolatrexed is a thymidylate synthase inhibitor with potential anticancer activity.Formule :C14H12N4OSDegré de pureté :97.91%Couleur et forme :SolidMasse moléculaire :284.34Ref: TM-T4228
1mg42,00€2mg50,00€5mg90,00€10mg148,00€25mg240,00€50mg430,00€100mg633,00€1mL*10mM (DMSO)96,00€BMH-21
CAS :BMH-21, a small molecule DNA intercalator, binds ribosomal DNA and inhibits RNA polymerase I (Pol I) transcription and not affects phosphorylation of H2AX.Formule :C21H20N4O2Degré de pureté :98.87% - 99.53%Couleur et forme :SolidMasse moléculaire :360.41Reozalimab
CAS :Rezilimab is a bispecific antibody that targets PD-1/PD-L1 and mediates antibody-dependent cell cytotoxicity (ADCC) in cancer research [1] [2].Degré de pureté :98%Couleur et forme :LiquidN1-Methylpseudouridine-5'-triphosphate
CAS :N1-Methylpseudouridine-5'-triphosphate is a modified nucleotide and can replace UTP in synthesis thereby improving RNA stability and reducing immunogenicity.Formule :C10H17N2O15P3Degré de pureté :98.18%Couleur et forme :SolidMasse moléculaire :498.17BMS-5
CAS :BMS-5 (LIMKi 3) is a potent LIMK inhibitor with IC50s of 7 nM and 8 nM for LIMK1 and LIMK2, respectively.Formule :C17H14Cl2F2N4OSDegré de pureté :95.83% - 99.88%Couleur et forme :SolidMasse moléculaire :431.29Ref: TM-T4598
1mg43,00€2mg55,00€5mg84,00€10mg123,00€25mg198,00€50mg298,00€100mg444,00€1mL*10mM (DMSO)92,00€Fialuridine
CAS :Fialuridine (DRG-0098), a DNA polymerase inhibitor, shows strong anti-HBV effects both in vitro and in vivo.Formule :C9H10FIN2O5Degré de pureté :99.71% - 99.90%Couleur et forme :Less Crystals Colourless CrystalsMasse moléculaire :372.09Ref: TM-T7655
1mg35,00€5mg74,00€10mg116,00€25mg235,00€50mg373,00€100mg562,00€500mg1.216,00€1mL*10mM (DMSO)82,00€CDK4/6-IN-24
CAS :CDK4/6-IN-24 (Compound A) is an inhibitor of CDK4/6 with broad-spectrum antitumor activity. It can effectively inhibit various cancer cells, exhibiting an IC50 in the submicromolar range.Formule :C32H41N7O3Couleur et forme :SolidMasse moléculaire :571.713Carotegrast methyl
CAS :Carotegrast methyl (AJM300), an orally-active small molecule, can antagonize the α4 integrin receptor. It is a specific and dual α4β1/α4β7 integrin antagonist.Formule :C28H26Cl2N4O5Degré de pureté :99.40%Couleur et forme :SolidMasse moléculaire :569.44Ref: TM-T30751
10g9.508,00€1mg74,00€5mg160,00€10mg264,00€25mg528,00€50mg785,00€100mg1.130,00€200mg1.549,00€1mL*10mM (DMSO)170,00€1ACTA
CAS :1ACTA (IRE1αS-nitrosylation inhibitor) is a compound that helps maintain the endoplasmic reticulum stress response under conditions of nitrosative stress.Formule :C14H16N2O2Couleur et forme :SolidMasse moléculaire :244.29NRTT-IN-1
CAS :NRTT-IN-1 (Compound 1) is an inhibitor of the nucleoside reverse transcriptase translocation (NRTT), effectively blocking HIV DNA synthesis and viral replication.Formule :C28H24FN5O5Couleur et forme :SolidMasse moléculaire :529.519PND-1186
CAS :PND-1186 (VS-4718) is a reversible and specific FAK inhibitor (IC50: 1.5 nM).Formule :C25H26F3N5O3Degré de pureté :99.14% - 99.75%Couleur et forme :SolidMasse moléculaire :501.5Catumaxomab
CAS :Catumaxomab is a rat-mouse hybrid lgG2 monoclonal and bispecific antibody that binds to the antigens CD3 and EpCAM for malignant ascites in cancer patients.Degré de pureté :95%Couleur et forme :LiquidPOL1-IN-1
CAS :POL1-IN-1 (Compound 3A) 是一种RNA 聚合酶 1 POL1抑制剂,IC50值低于 0.5 uM。 它能有效抑制A375恶性黑色素瘤细胞系中RNA 聚合酶I 的转录。Formule :C21H20N6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :356.42Rac1 Inhibitor W56 acetate(1095179-01-3 free base)
Rac1 Inhibitor W56 acetate(1095179-01-3 free base) is a peptide comprising residues 45-60 of the guanine nucleotide exchange factor (GEF) recognition/activationFormule :C76H121N19O25SDegré de pureté :98.96%Couleur et forme :SolidMasse moléculaire :1732.95CAF-382
CAF-382 (compound B1), an analog of SNS-032, functions as a CDKL5 and pan-CDK inhibitor, exhibiting modest inhibitory activity against GSK3α/β with an affinityFormule :C16H22N4O2S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :366.5PD-L1-IN-3
CAS :PD-L1-IN-3 is a PD-1/PD-L1 inhibitor for the study of tumors and immune diseases.Formule :C19H15ClFN2OSDegré de pureté :99.47%Couleur et forme :SoildMasse moléculaire :373.85DHX9-IN-2
CAS :DHX9-IN-2 is an inhibitor targeting ATP-dependent RNA de-helicase A (DHX9) with anticancer and antitumor activity for cancer research.Formule :C18H16ClN3O3S2Degré de pureté :98.00%Couleur et forme :SolidMasse moléculaire :421.92β-glycosidase-IN-1
CAS :β-glycosidase-IN-1 is a piperidine derivative, and is an inhibitor of β-glycosidase. It has hypoglycemic activity.Formule :C13H23NO5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :273.33Orotic acid
CAS :Orotic acid (Vitamin B13) is an intermediate product in pyrimidine metabolism.Formule :C5H4N2O4Degré de pureté :99.42%Couleur et forme :Crystals Physical Description White Crystals Or Crystalline Powder (Ntp 1992)Masse moléculaire :156.1IDD388
CAS :IDD388 is a selective and potent aldose reductase (ALR2) inhibitor with antitumor activity that inhibits the ALR1 receptor.Formule :C16H12BrClFNO4Degré de pureté :99.56%Couleur et forme :SolidMasse moléculaire :416.63BTYNB
CAS :BTYNB (MDK6620) is an inhibitor of the oncofetal mRNA-binding protein IMP1. MDK6620 downregulates β-TrCP1 mRNA and reduces activation of NF-κB.Formule :C12H9BrN2OSDegré de pureté :99.91% - ≥95%Couleur et forme :SolidMasse moléculaire :309.18Ref: TM-T9033
5mg48,00€10mg63,00€25mg93,00€50mg136,00€100mg198,00€200mg309,00€500mg563,00€1mL*10mM (DMSO)50,00€Orbofiban TFA
CAS :Orbofiban TFA is an orally active GPIIb/IIIa platelet receptor antagonist with inhibitory effects on platelet aggregation for the study of unstable coronaryFormule :C19H24F3N5O6Degré de pureté :97.45% - 98.43%Couleur et forme :SolidMasse moléculaire :475.42PLN-1474
CAS :PLN-1474 is a potent αVβ1 inhibitor with IC50 < 50 nM.Formule :C24H37N3O4Degré de pureté :99.25%Couleur et forme :SoildMasse moléculaire :431.57Ref: TM-T60101
1mg52,00€5mg111,00€10mg180,00€25mg305,00€50mg439,00€100mg612,00€1mL*10mM (DMSO)124,00€RdRP-IN-6
RdRP-IN-6 (compound 27) is an inhibitor of RNA-dependent RNA polymerase (RdRp), exhibiting an IC90 value of 14.1 μM.Formule :C41H67N8O7PSi2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :871.16Firategrast
CAS :Firategrast (SB 683699) is an orally active and specific α4β1/α4β7 integrin antagonist.Firategrast reduces the transport of lymphocytes into the central nervousFormule :C27H27F2NO6Degré de pureté :99.16%Couleur et forme :SolidMasse moléculaire :499.5Ref: TM-TQ0291
1mg47,00€5mg87,00€10mg140,00€25mg283,00€50mg464,00€100mg747,00€200mg1.017,00€1mL*10mM (DMSO)97,00€Pacmilimab
CAS :Pacmilimab (CX-072) is a Probody immune checkpoint inhibitor targeting programmed death ligand 1 (PD-L1) with anti-tumor activity for the study of solid tumors.Degré de pureté :95% - 95%Couleur et forme :LiquidNUAK1-IN-1
NUAK1-IN-1 (Compound 9) is an inhibitor of NUAK1 with an IC50 of 5.012 nM, as well as a CDK4 inhibitor. It is suitable for research related to cancer, neurodevelopmental disorders, and Alzheimer's disease.Formule :C25H30N6OCouleur et forme :SolidMasse moléculaire :430.545MLN8054
CAS :MLN8054 is a potent and selective Aurora A kinase inhibitor with an IC50 of 4 nM.Formule :C25H15ClF2N4O2Degré de pureté :98.07% - 98.26%Couleur et forme :SolidMasse moléculaire :476.86Ref: TM-T6315
1mg52,00€2mg71,00€5mg88,00€10mg127,00€25mg233,00€50mg376,00€100mg567,00€1mL*10mM (DMSO)93,00€2,5-Di-tert-butyl-1,4-benzoquinone
CAS :2,5-Di-tert-butyl-1,4-benzoquinone is a potent antibacterial agent found primarily in marine Streptomyces sp. VITVSK1, effective against emerging antibiotic resistance. Additionally, it serves as a powerful inhibitor of RNA polymerase.Formule :C14H20O2Couleur et forme :SolidMasse moléculaire :220.31AS-0141
CAS :AS-0141 (Cdc7-IN-6) 是一种有效的 Cdc7 激酶抑制剂 (IC50=4 nM),具有抗肿瘤活性。Cdc7 是一种丝氨酸苏氨酸蛋白激酶酶,在细胞周期中对 DNA 复制的启动至关重要。Formule :C21H22F3N5O4Degré de pureté :100%Couleur et forme :SolidMasse moléculaire :465.43DI-87
CAS :DI-87 (TRE-515) is a novel and orally available dCK (deoxycytidine kinase) inhibitor. DI-87 binds to dCK reduces the production of dNTP inhibits tumor growth.Formule :C23H30N6O3S2Degré de pureté :99.76%Couleur et forme :SolidMasse moléculaire :502.65Levoleucovorin Calcium
CAS :Levoleucovorin Calcium (CL307782), a calcium salt of the folinic acid, is used in cancer chemotherapy as an adjuvant.Formule :C20H21N7O7·CaDegré de pureté :98.46% - ≥98%Couleur et forme :White Crystalline PowderMasse moléculaire :511.5PROTAC CDK9 degrader-6
CAS :PROTAC CDK9 degrader-6 targets and degrades CDK9 isoforms via proteasome, with DC50 of 0.10μM and 0.14μM.Formule :C42H49Cl2N9O8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :878.8THZ1-R
CAS :THZ1-R displays diminished activity for CDK7 inhibition(Kd:142 nM).Formule :C31H30ClN7O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :568.07CLK1-IN-1
CAS :CLK1-IN-1 is a potent and selective inhibitor of the Cdc2-like kinase 1 (CLK1; IC50: 2 nM).Formule :C24H16FN5OCouleur et forme :SolidMasse moléculaire :409.42Teclistamab
CAS :Teclistamab(JNJ-64007957) is a human bispecific monoclonal antibody targeting the CD3 receptor on t-cells and the BCMA for relapsed and refractory multiple myeloma.Degré de pureté :95%Couleur et forme :LiquidCDK-TCIP2
DK-TCIP2 is an anticancer agent formed by linking the CDK9 inhibitor SNS-032 and the BCL6 inhibitor BI-3812. This compound exhibits anticancer activity both in vivo and in vitro, making it suitable for research in lymphoma.Formule :C52H67ClN12O8S2Couleur et forme :SolidMasse moléculaire :1087.75SIBA
CAS :SIBA, a synthetic SAH analog, inhibits SAM-dependent transmethylation and blocks HSV-1 replication.Formule :C14H21N5O3SDegré de pureté :99.48%Couleur et forme :SolidMasse moléculaire :339.41Ref: TM-T12908
1mg52,00€5mg94,00€10mg117,00€25mg220,00€50mg329,00€100mg469,00€200mg652,00€1mL*10mM (DMSO)104,00€(R)-Simurosertib
CAS :(R)-Simurosertib ((R)-TAK-931) is an inhibitor of the ATP-competitive cell division cycle 7 (CDC7) kinase.Formule :C17H19N5OSDegré de pureté :99.64%Couleur et forme :SolidMasse moléculaire :341.43JNJ-7706621
CAS :JNJ-7706621 is a potent aurora kinase inhibitor, and also inhibits CDK1 and CDK2.Formule :C15H12F2N6O3SDegré de pureté :99.1% - 99.66%Couleur et forme :SolidMasse moléculaire :394.36Ref: TM-T6126
1mg50,00€2mg66,00€5mg105,00€10mg180,00€25mg284,00€50mg520,00€100mg728,00€500mg1.473,00€1mL*10mM (DMSO)88,00€2'-Deoxy-2'-fluorocytidine
CAS :2'-Deoxy-2'-fluorocytidine is an nucleoside analog and inhibits of Crimean-Congo hemorrhagic fever virus (CCHFV) replication potently.Formule :C9H12FN3O4Degré de pureté :99.03%Couleur et forme :White Or Almost White Crystalline PowderMasse moléculaire :245.21Bleomycin hydrochloride
CAS :Bleomycin hydrochloride is a potent antitumor antibiotic that functions as a DNA synthesis inhibitor and DNA damaging agent.Formule :C55H84ClN17O21S3Degré de pureté :98%Couleur et forme :SoildMasse moléculaire :1451.01(Average)Mithramycin A
CAS :Mithramycin A (Plicamycin), a DNA-binding antitumor antibiotic, is a selective specificity protein 1 (Sp1) inhibitor, which inhibits the growth of variousFormule :C52H76O24Degré de pureté :99.28%Couleur et forme :Yellow PowderMasse moléculaire :1085.15CCT245737
CAS :CCT245737 is an orally active, selective Chk1 inhibitor, and is >1,000-fold selective over CHK2 and CDK1.Cost-effective and quality-assured.Formule :C16H16F3N7ODegré de pureté :97.06% - 99.69%Couleur et forme :SolidMasse moléculaire :379.34Ref: TM-T7080
1mg39,00€2mg51,00€5mg84,00€10mg119,00€25mg225,00€50mg369,00€100mg552,00€1mL*10mM (DMSO)92,00€DNA gyrase B-IN-3
CAS :DNA gyrase B-IN-3 (Compound A), with an IC50 of less than 10 nM, acts as an inhibitor of bacterial DNA gyrase B and exhibits antibacterial activity against GramFormule :C14H9Cl2N3O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :386.21IRES-C11
CAS :IRES-C11 is a specific inhibitor of translation that targets the internal ribosome entry site (IRES) of the c-MYC gene. It functions by blocking the interaction between heterogeneous nuclear ribonucleoprotein A1, a trans-acting factor required for c-MYC IRES activity, and its corresponding IRES. Notably, IRES-C11 does not inhibit the IRES activity of BAG-1, XIAP, and p53.Formule :C13H11Cl2NO4Degré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :316.14Ref: TM-T40419
1mg103,00€5mg246,00€10mg395,00€25mg785,00€50mg1.198,00€100mg1.853,00€200mg2.498,00€1mL*10mM (DMSO)271,00€STF-083010
CAS :STF-083010 is a selective inhibitor of the IRE1α endonuclease.Formule :C15H11NO3S2Degré de pureté :97.53% - 98.85%Couleur et forme :SolidMasse moléculaire :317.38Ref: TM-T6681
5mg51,00€10mg80,00€25mg120,00€50mg205,00€100mg368,00€200mg555,00€500mg810,00€1mL*10mM (DMSO)58,00€ARB-272572
CAS :ARB-272572 is a PD-L1 signaling inhibitor that produces immunostimulatory activity in human primary cells.Formule :C32H36N6O4Degré de pureté :97.36% - 98.07%Couleur et forme :SolidMasse moléculaire :568.675-Bromo-2',3',5'-tri-O-acetyluridine
CAS :5-Bromo-2',3',5'-tri-O-acetyluridine is a purine nucleoside analog that can be used to explore explore improve Parkinson's disease.Formule :C15H17BrN2O9Degré de pureté :99%Couleur et forme :SolidMasse moléculaire :449.21(E/Z)-THZ1 2HCl
CAS :THZ1 2HCl: selective CDK7 allosteric inhibitor, IC50 3.2 nM, hinders cancer cell growth.Formule :C31H30Cl3N7O2Degré de pureté :98.33%Couleur et forme :SolidMasse moléculaire :638.98TASIN-1
CAS :TASIN-1 is a small molecule inhibitor of mutant adenomatous polyposis coli (APC).Formule :C18H28N2O3SDegré de pureté :98.48%Couleur et forme :SolidMasse moléculaire :352.49Ref: TM-T22632
1mg39,00€5mg84,00€10mg131,00€25mg269,00€50mg432,00€100mg638,00€500mg1.359,00€1mL*10mM (DMSO)92,00€GSK2850163
CAS :GSK2850163 is a novel inhibitor of inositol-requiring enzyme-1 alpha (IRE1α) which can inhibit RNase activity and IRE1α kinase activity (IC50s: 200 and 20 nM).Formule :C24H29Cl2N3ODegré de pureté :98.44%Couleur et forme :SolidMasse moléculaire :446.41Phthalazinone pyrazole
CAS :Phthalazinone pyrazole: a potent, selective oral Aurora-A kinase inhibitor, overexpressed in tumors with oncogenic activity.Formule :C18H15N5ODegré de pureté :97.03%Couleur et forme :SolidMasse moléculaire :317.34Ref: TM-T21981
1mg64,00€2mg96,00€5mg145,00€10mg212,00€25mg353,00€50mg532,00€100mg792,00€200mg1.064,00€EHT 1864 2HCl
CAS :EHT 1864 (EHT 1864 2HCl) is a Rac family GTPase inhibitor that blocks activation by direct binding to Rac1, Rac1b, Rac2, and Rac3. Cost effective and quality assured.Formule :C25H29Cl2F3N2O4SDegré de pureté :98.39% - 99.42%Couleur et forme :SolidMasse moléculaire :581.47Ref: TM-T6483
1mg47,00€5mg92,00€10mg136,00€25mg259,00€50mg472,00€100mg677,00€200mg934,00€1mL*10mM (DMSO)107,00€(D)-PPA 1 TFA
(D)-PPA 1 TFA is a hydrolysis-resistant D-peptide antagonist and a potent PD-1/PD-L1 inhibitor, exhibiting an affinity for PD-1 of 0.51 μM and demonstratingFormule :C72H99F3N20O23Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1669.67H1k
H1k is an eudistomin Y fluorescent derivative and lysosome-targeted antiproliferative agent that downregulates the expression of cell cycle protein B1.Formule :C27H22N2ODegré de pureté :98.38%Couleur et forme :SoildMasse moléculaire :390.48Nocarnickelamides B
Nocarnickelamides B (Compound 2) is a linear peptide and an inhibitor of ROCK1/2. It exhibits dual inhibitory activity against ROCK1 and ROCK2, with IC50 values of 14.9 μM and 21.9 μM, respectively. This compound binds to the ATP binding site and inhibits ROCK-mediated cytoskeletal contraction markers, such as myosin light chain activation. Nocarnickelamides B can be utilized in glaucoma research.Formule :C29H42N6O9Couleur et forme :SolidMasse moléculaire :618.68LXW7
CAS :LXW7 is an octamer disulfide cyclic peptide and αvβ3 integrin ligand, acts as a potent and specific endothelial progenitor cells (EPCs) and endothelial cells (Formule :C29H48N12O12S2Degré de pureté :100%Couleur et forme :SolidMasse moléculaire :820.89HALOFUGINONE LACTATE
CAS :HALOFUGINONE LACTATE is a halogenated derivative of febrifugine, a natural quinazolinone-containing compound found in the Chinese herb D.Formule :C19H23BrClN3O6Degré de pureté :99.02% - 99.96%Couleur et forme :SolidMasse moléculaire :504.8Ref: TM-T8785
2mg42,00€5mg59,00€10mg94,00€25mg130,00€50mg207,00€100mg309,00€200mg462,00€1mL*10mM (DMSO)66,00€Amsilarotene
CAS :Amsilarotene (TAC101) blocks RB phosphorylation, boosts 2 CDK inhibitors, halts cell cycle, and reduces thymidylate synthase and cyclin A levels.Formule :C20H27NO3Si2Degré de pureté :99.27%Couleur et forme :SolidMasse moléculaire :385.6Ref: TM-T21314
1mg43,00€2mg57,00€5mg96,00€10mg140,00€25mg273,00€50mg393,00€100mg560,00€200mg757,00€1mL*10mM (DMSO)96,00€ARRY 520 hydrochloride
CAS :'ARRY 520 hydrochloride: a KSP inhibitor causing apoptosis and strong anti-proliferative effects.'Formule :C20H23ClF2N4O2SDegré de pureté :98.06% - 99.26%Couleur et forme :SolidMasse moléculaire :456.94Ref: TM-TQ0318L
1mg59,00€5mg116,00€10mg170,00€25mg304,00€50mg437,00€100mg615,00€200mg830,00€1mL*10mM (DMSO)149,00€