
Cycle cellulaire/point de contrôle
Les inhibiteurs du cycle cellulaire/des points de contrôle sont des composés qui perturbent la progression normale du cycle cellulaire, en particulier aux points de contrôle régulateurs clés. Ces inhibiteurs sont cruciaux pour étudier la division cellulaire, comprendre la prolifération des cellules cancéreuses et développer des thérapies anticancéreuses. En ciblant des phases spécifiques du cycle cellulaire, ces inhibiteurs peuvent induire un arrêt du cycle cellulaire, conduisant à l'apoptose ou à la sénescence des cellules à division rapide. Chez CymitQuimica, nous offrons une large gamme d'inhibiteurs de haute qualité du cycle cellulaire/des points de contrôle pour soutenir vos recherches en biologie du cancer, biologie cellulaire et développement de médicaments.
Sous-catégories appartenant à la catégorie "Cycle cellulaire/point de contrôle"
- Aurora Kinase
- CDK
- Arrêt du cycle cellulaire
- Chk
- c-Myc
- Dynamine
- DYRK
- Ferroptose
- HSP
- Intégrine
- Kinésine
- KSP
- LIM Kinase
- Microtubules associés
- PKC
- PLK
- Rho
- ROCK
- Wee1
Affichez 11 plus de sous-catégories
Produits appartenant à la catégorie "Cycle cellulaire/point de contrôle"
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L 888607 Racemate
CAS :L 888607 Racemate blocks DP1 and TP receptors with 132 nM and 17 nM affinity.Formule :C19H15ClFNO2SCouleur et forme :SolidMasse moléculaire :375.84Arginine-glycine-aspartic acid
CAS :RGD (RGD (Arg-Gly-Asp) Peptides) (Arg-Gly-Asp) Peptides is a cell adhesion motif which can mimic cell adhesion proteins and bind to integrins.Formule :C12H22N6O6Degré de pureté :99.11%Couleur et forme :SolidMasse moléculaire :346.34Valategrast hydrochloride
CAS :Valategrast hydrochloride (R411), a dual antagonist of integrin α4β1 (VLA-4), is used for the potential treatment of asthma.Formule :C30H33Cl4N3O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :641.41Ascamycin
CAS :Ascamycin: a Streptomyces-made antibiotic targeting Xanthomonas spp. MIC: 0.4-12.5 μg/mL for X. citri, oryzae, and phage.Formule :C13H18ClN7O7SDegré de pureté :99.29%Couleur et forme :SolidMasse moléculaire :451.84Ref: TM-T14329
1mg333,00€5mg787,00€10mg1.074,00€25mg1.510,00€50mg1.882,00€100mg2.375,00€500mg4.655,00€1mL*10mM (DMSO)747,00€(E/Z)-ZINC09659342
CAS :(E/Z)-ZINC09659342 is an inhibitor of Lbc-Rho A interaction.Formule :C23H15F3N2O4Degré de pureté :95.83%Couleur et forme :SolidMasse moléculaire :440.37Ref: TM-T9986
1mg66,00€5mg145,00€10mg221,00€25mg378,00€50mg533,00€100mg718,00€200mg938,00€1mL*10mM (DMSO)160,00€Irigenin
CAS :Irigenin mediates its antimetastatic effect by specifically and selectively blocking the α9β1 and α4β1 integrin binding sites on the C-C loop of the ExtraFormule :C18H16O8Degré de pureté :99.50% - 99.85%Couleur et forme :SolidMasse moléculaire :360.315-BrdU
CAS :5-BrdU (Broxuridine) , a nucleoside analog, are used in the detection of proliferating cells and competes with thymidine for incorporation into DNA.Formule :C9H11BrN2O5Degré de pureté :99.54% - 99.87%Couleur et forme :Crystals From Absolute Ethanol Physical Description White Crystalline Powder (Ntp 1992)Masse moléculaire :307.1Bersanlimab
CAS :Bersanlimab (BI-505) is a fully human monoclonal antibody targeting Intercellular Adhesion Molecule-1 (ICAM-1).Bersanlimab has anticancer properties.Degré de pureté :> 95% - > 95%Couleur et forme :LiquidMasse moléculaire :144.22 kDa5-Azacytidine
CAS :5-Azacytidine (Ladakamycin) is a cytidine nucleoside analog, a DNA methylation inhibitor with specificity.Formule :C8H12N4O5Degré de pureté :99.31% - 99.79%Couleur et forme :Crystals From Methanol Physical Description White Crystalline Powder (Ntp 1992)Masse moléculaire :244.2(R)-Atuveciclib
CAS :Atuveciclib (BAY-1143572) is a potent and highly selective, oral PTEFb / CDK9 inhibitor that inhibits CDK9 / CycT1 with an IC 50 of 13 nM [1].Formule :C18H18FN5O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :387.43αvβ1 integrin-IN-1 TFA (1689540-62-2 free base)
αvβ1 integrin-IN-1 TFA is an effective and selective αvβ1 integrin inhibitor (IC50: 0.63 nM).Formule :C28H35F3N6O8SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :672.67VER-00158411
CAS :VER-00158411 is a checkpoint kinase 1 and CHK2 inhibitor (IC50: 4.4 nM and 4.5 nM, respectively).Formule :C31H34N6O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :538.64NSC 617145
CAS :NSC 617145 (NSC617145) is an inhibitor of WRN helicase that inhibits the ATPase, but not exonuclease, activity of WRN helicase in a concentration-dependentFormule :C13H10Cl4N2O4Degré de pureté :98.31% - 99.72%Couleur et forme :SolidMasse moléculaire :400.04Ref: TM-T9168
1mg37,00€2mg52,00€5mg77,00€10mg96,00€25mg167,00€50mg240,00€100mg378,00€500mg889,00€1mL*10mM (DMSO)85,00€WRN inhibitor 15
WRN inhibitor 15 (Compound 9) is a WRN inhibitor with antitumor properties, displaying IC50 values of 37.9, 40.2, and 46.6 μM in PC3, LNCaP, and HeLa cells, respectively, making it suitable for prostate cancer research.Formule :C16H13F2N3OCouleur et forme :SolidMasse moléculaire :301.29αvβ6-IN-1
αvβ6-IN-1 (compound 28) is an effective orally active inhibitor of αvβ6 integrin (αvβ6integrin), with a pIC50 value of 8.1. This compound shows potential for research in idiopathic pulmonary fibrosis.Formule :C25H32F2N4O3Couleur et forme :SolidMasse moléculaire :474.543'-Deoxy-3'-fluoroadenosine
CAS :3'-Deoxy-3'-fluoroadenosine is a purine nucleoside analogue with a wide range of anti-tumor and anti-viral activity, and has inhibitory effects on tick-borneFormule :C10H12FN5O3Degré de pureté :99.84%Couleur et forme :SolidMasse moléculaire :269.23Synucleozid hydrochloride
CAS :Synucleozid hydrochloride inhibits the translation of the intrinsically disordered protein α-synuclein by targeting its structured mRNA.Formule :C22H21ClN6Degré de pureté :98.13%Couleur et forme :SolidMasse moléculaire :404.9CNDAC hydrochloride
CAS :CNDAC hydrochloride, a nucleoside analog, is a metabolite of the sapacitabine.Formule :C10H13ClN4O4Degré de pureté :99.69%Couleur et forme :SolidMasse moléculaire :288.69Ref: TM-T13621
1mg114,00€5mg274,00€10mg425,00€25mg702,00€50mg938,00€100mg1.311,00€1mL*10mM (DMSO)250,00€K858 (Racemic)
CAS :K858 Racemic (K858) is a selective mitotic kinesin Eg5 inhibitor which acts in an ATP-noncompetitive manner.Formule :C13H15N3O2SDegré de pureté :100%Couleur et forme :SolidMasse moléculaire :277.34RX-3117
CAS :RX-3117 (fluorocyclopentenylcytosine) is a novel a cytidine analog.Formule :C10H12FN3O4Degré de pureté :99.55%Couleur et forme :SolidMasse moléculaire :257.22Ref: TM-T16813
1mg157,00€2mg212,00€5mg309,00€10mg444,00€25mg728,00€50mg1.017,00€100mg1.378,00€1mL*10mM (DMSO)319,00€CDK7-IN-25
CAS :CDK7-IN-25 (CY-16-1) is a potent CDK7 inhibitor with an IC50 value of less than 1nM, utilized in cancer research [1].Formule :C33H32N6O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :560.65Betamethasone 17-benzoate
CAS :Betamethasone 17-benzoate is a representative steroid. It also can be used in the treatment of recurrent aphothous ulcers (RAU).Formule :C29H33FO6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :496.57CDK4-IN-2
CAS :CDK4-IN-2 (A17) is a potent inhibitor of CDK4, exhibiting K i and IC 50 values of less than 10 nM and is utilized in cancer research [1].Formule :C22H26F2N6O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :508.54CDK2-IN-20
CDK2-IN-20 (compound 3b), a CDK2 inhibitor, exhibits cytotoxic effects on tumor cells with an IC50 ranging from 5.52-17.09 µM.Degré de pureté :98%Couleur et forme :Odour SolidCDK4/9-IN-1
CAS :CDK4/9-IN-1 (Compound 29) is a selective dual inhibitor of CDK4 and CDK9, exhibiting IC50 values of 23 nM and 12 nM, respectively. It holds potential for use in cancer research.Formule :C22H34N6O2Couleur et forme :SolidMasse moléculaire :414.544Spartalizumab
CAS :"Spartalizumab (PDR001), a humanized IgG4 monoclonal antibody, targets PD-1 to inhibit PD-L1/L2 interactions, useful in ATC research."Degré de pureté :SDS-PAGE:95.2%;SEC-HPLC:96.3%Couleur et forme :LiquidMasse moléculaire :145.74 kDaPurvalanol B
CAS :Purvalanol B (NG 95) is a CDK inhibitor that inhibits Cdk2/cyclin A, Cdk2/cyclin E, Cdk5/p35, and Cdk2/cyclin B (IC50s = 6, 9, 6, and 6 nM, respectively)Formule :C20H25ClN6O3Degré de pureté :98.95%Couleur et forme :SolidMasse moléculaire :432.9Ref: TM-T7167
1mg38,00€5mg73,00€10mg95,00€25mg148,00€50mg215,00€100mg323,00€200mg487,00€1mL*10mM (DMSO)81,00€Visugromab
CAS :Visugromab, a GDF-15 neutralizing IgG4 monoclonal antibody (mAb), demonstrates potent efficacy in treating PD-1/PD-L1 relapsed/refractory metastatic solidDegré de pureté :98%Couleur et forme :LiquidN6-(p-Methoxybenzyl)adenosine
CAS :Nucleoside Derivatives - 6-Modified purine nucleosides; Drugs and Inhibitors; plant growth regulator, plant hormoneFormule :C18H21N5O5Degré de pureté :99.79%Couleur et forme :SolidMasse moléculaire :387.39L-Methioninamide hydrochloride
CAS :L-Methioninamide hydrochloride is a potent inhibitor of methionyl-tRNA synthetase that reduces the toxicity of CDDP.Formule :C5H13ClN2OSDegré de pureté :99.75%Couleur et forme :SolidMasse moléculaire :184.692'-O-(2-Methoxyethyl)adenosine
CAS :2'-O-(2-Methoxyethyl)adenosine is a nucleoside analog used to improve RNA target affinity and nuclease resistance of therapeutic oligonucleotides in preclin.Formule :C13H19N5O5Degré de pureté :99.35%Couleur et forme :SolidMasse moléculaire :325.32Uridine triphosphate 13C9,15N2 sodium
CAS :Uridine triphosphate 13C9,15N2 sodium is an isotopically labeled.UTP is a key in RNA synthesis molecule a substrate for RNA polymerase.Formule :C9H1415N2NaO15P3Couleur et forme :SolidMasse moléculaire :517.04BI-1347
CAS :BI-1347 is a potent, selective inhibitor of CDK8/cyclinC (IC50: 1 nM). It shows tumor growth inhibition in an in vivo xenograft model.Formule :C22H20N4ODegré de pureté :96.7% - 99.43%Couleur et forme :SolidMasse moléculaire :356.42Ref: TM-T5405
1mg40,00€5mg88,00€10mg126,00€25mg240,00€50mg439,00€100mg647,00€500mg1.359,00€1mL*10mM (DMSO)87,00€Nofazinlimab
CAS :Nofazinlimab (CS1003) is a human anti-PD-1 IgG4 monoclonal antibody for the study of unresectable hepatocellular carcinoma (uHCC).Couleur et forme :LiquidCDK9-IN-8
CAS :CDK9-IN-8 is a highly potent and selective CDK9 inhibitor (IC50: 12 nM).Formule :C31H32FN7O3Degré de pureté :98.77%Couleur et forme :SolidMasse moléculaire :569.63RI-1
CAS :RI-1 (RAD51 inhibitor 1) is a RAD51 inhibitor (IC50: 5-30 μM).Formule :C14H11Cl3N2O3Degré de pureté :99.3% - 99.62%Couleur et forme :SolidMasse moléculaire :361.61Ganciclovir sodium
CAS :Ganciclovir sodium, a sodium salt with anti-CMV and HSV-1 antiviral properties.Formule :C9H13N5NaO4Degré de pureté :99.47%Couleur et forme :SolidMasse moléculaire :278.226-Hydroxy-DOPA
CAS :6-Hydroxy-DOPA is an allosteric inhibitor of RAD52, it inhibits proliferation of BRCA-deficient cancer cells in vitro and also inhibits APE1.Formule :C9H11NO5Degré de pureté :96.59% - 97.23%Couleur et forme :SolidMasse moléculaire :213.19Adavosertib
CAS :Adavosertib (MK-1775) is a small molecule inhibitor of the checkpoint kinase WEE1 (IC50: 5.2 nM). It hinders the G2 DNA damage checkpoint.Formule :C27H32N8O2Degré de pureté :100% - 99.82%Couleur et forme :SolidMasse moléculaire :500.6Ref: TM-T2077
5mg48,00€10mg70,00€25mg86,00€50mg92,00€100mg116,00€200mg170,00€500mg274,00€1mL*10mM (DMSO)52,00€Camrelizumab
CAS :Camrelizumab (SHR-1210) is a human IgG4-κ monoclonal antibody with high affinity and directed against PD-1.Camrelizumab binds PD-1 with a binding affinity of upDegré de pureté :98.6%Couleur et forme :LiquidMasse moléculaire :143.7 kDaGSK2850163 (S enantiomer)
CAS :GSK2850163 (S enantiomer) is the inactive enantiomer of GSK2850163. GSK2850163 is an novel inhibitor of inositol-requiring enzyme-1 alpha (IRE1a).Formule :C24H29Cl2N3ODegré de pureté :98.40%Couleur et forme :SolidMasse moléculaire :446.41Cyclo(RADfK)
CAS :Cyclo(RADfK) is a selective α(v)β(3) integrin ligand used in neoangiogenesis research, therapy, and diagnostics; it's a control for RGD peptides.Formule :C28H43N9O7Degré de pureté :100%Couleur et forme :SolidMasse moléculaire :617.7LDC-4297 HCl (1453834-21-3(free base))
LDC4297 is a potent and selective CDK7 inhibitor with an IC50 of 0.13 nM.Formule :C23H29ClN8ODegré de pureté :100%Couleur et forme :SolidMasse moléculaire :469.02Ref: TM-T4417
1mg59,00€2mg85,00€5mg97,00€10mg172,00€25mg339,00€50mg502,00€100mg728,00€1mL*10mM (DMSO)97,00€GRGDSPK
CAS :GRGDSPK (EMD 56574) is an inhibitory peptide for RGD-mediated adhesion between integrin and extracellular matrix molecules.Formule :C28H49N11O11Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :715.76ZNL-05-044
ZNL-05-044, a CDK11 inhibitor, exhibits IC50 values of 0.23 μM for CDK11A and 0.27 μM for CDK11B, as determined by NanoBRET assay.Formule :C21H22Cl2N6OSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :477.41MDEG-541
MDEG-541 is a potent MYC-MAX degrader that exhibits antiproliferative activity by downregulating the expression of GSPT1, MYC, GSPT2, and PLK1 proteins [1].Formule :C35H38N4O7SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :658.76TAK-960
CAS :TAK-960 is an orally bioavailable, selective inhibitor of Plks with IC50 values of 0.8, 16.9, and 50.2 nM for Plk1, Plk2, and Plk3, respectively.Formule :C27H34F3N7O3Degré de pureté :97.06%Couleur et forme :SolidMasse moléculaire :561.6Ref: TM-T7200
1mg64,00€2mg89,00€5mg120,00€10mg170,00€25mg294,00€50mg490,00€100mg710,00€1mL*10mM (DMSO)170,00€BRD32048
CAS :BRD32048 is a top candidate ETV1 perturbagen. BRD32048 inhibits p300-dependent acetylation of ETV1, thereby promoting its degradation.Formule :C16H22N6ODegré de pureté :99.69%Couleur et forme :SolidMasse moléculaire :314.39Ref: TM-T23820
2mg52,00€5mg111,00€10mg175,00€25mg321,00€50mg512,00€100mg825,00€200mg1.111,00€1mL*10mM (DMSO)47,00€UNC9512
UNC9512 is a potent antagonist of the methyl-lysine reader protein 53BP1, which can be utilized to investigate the function of 53BP1 in DNA repair, gene editingFormule :C31H34N6O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :538.64(E/Z)-Rigosertib sodium
CAS :ON-01910 is a non-ATP-competitive PLK1 inhibitor(IC50 of 9 nM, in a cell-free assay).Formule :C21H24NNaO8SDegré de pureté :97.16% - 99.82%Couleur et forme :SolidMasse moléculaire :473.47CCT129202
CAS :CCT129202 is an ATP-competitive pan-Aurora inhibitor for Aurora A, Aurora B and Aurora C with IC50 of 0.042 μM, 0.198 μM and 0.227 μM, respectively.Formule :C23H25ClN8OSDegré de pureté :98.14%Couleur et forme :SolidMasse moléculaire :497.02Elarofiban
CAS :Elarofiban(RWJ-53308) is a novel and orally active GPIIb/IIIa antagonist.Formule :C22H32N4O4Degré de pureté :99.94%Couleur et forme :SolidMasse moléculaire :416.51p21PBP
p21PBP, a peptide composed of 20 amino acids, serves as an inhibitor of DNA replication. It specifically binds to the purified proliferating cell nuclear antigen (PCNA) found in extracts from tumor cells. p21PBP holds potential for use in cancer research.Formule :C112H181N37O30SCouleur et forme :SolidMasse moléculaire :2557.93Cdk2 Inhibitor II
CAS :Cdk2 Inhibitor II is a selective and potent CDK2 inhibitor50 at 60 nM.Formule :C14H11BrN4O3SDegré de pureté :98.38%Couleur et forme :SolidMasse moléculaire :395.23Ref: TM-T36933
1mg103,00€2mg140,00€5mg202,00€10mg305,00€25mg512,00€50mg730,00€100mg998,00€500mg1.977,00€IXA4
CAS :IXA4 is a highly selective, nontoxic activator of IRE1/XBP1s and reduces APP secretion by activating IRE1.Formule :C24H28N4O4Degré de pureté :97.59% - 98.69%Couleur et forme :SolidMasse moléculaire :436.5YK-2168
CAS :YK-2168 is a differentiated selective inhibitor of CDK9.Formule :C16H18ClN5Couleur et forme :SolidMasse moléculaire :315.80PF07104091
CAS :PF07104091 inhibits CDK2, which may lead to cell cycle arrest, induce apoptosis and inhibit tumor cell proliferation. Cost-effective and quality-assured.Formule :C19H28N6O4Degré de pureté :98.61%Couleur et forme :SolidMasse moléculaire :404.46Ref: TM-T9712
1mg354,00€2mg518,00€5mg823,00€10mg1.206,00€25mg1.795,00€50mg2.422,00€100mg3.258,00€1mL*10mM (DMSO)914,00€2'-Fluoro-2'-Deoxyadenosine
CAS :2'-Fluoro-2'-Deoxyadenosine is efficiently cleaved to the toxic 2-fluoroadenine (FAde) by Escherichia coli purine nucleoside phosphorylase (PNP).Formule :C10H12FN5O3Degré de pureté :99.35%Couleur et forme :SolidMasse moléculaire :269.23BMS-265246
CAS :BMS-265246 is a potent and selective CDK1/2 inhibitor.Formule :C18H17F2N3O2Degré de pureté :98.77% - 99.55%Couleur et forme :SolidMasse moléculaire :345.34Ref: TM-T2679
1mg35,00€5mg74,00€10mg116,00€25mg221,00€50mg335,00€100mg480,00€200mg652,00€1mL*10mM (DMSO)82,00€2'-Deoxy-5,6-dihydrouridine
CAS :2'-Deoxy-5,6-dihydrouridine is a nucleoside analog that contains a dihydro group in its molecular structure,commonly used in base excision related studies.Formule :C9H14N2O5Degré de pureté :99.75%Couleur et forme :SolidMasse moléculaire :230.229-(β-D-Xylofuranosyl)adenine
CAS :9-(β-D-Xylofuranosyl)adenine (Adenine xyloside) is an adenine nucleoside analog that is a potential smooth muscle vasodilator.9-(β-D-Xylofuranosyl)adenine hasFormule :C10H13N5O4Degré de pureté :99.55%Couleur et forme :SolidMasse moléculaire :267.24PVZB1194
CAS :PVZB1194, a biphenyl-type inhibitor of Kinesin spindle protein Eg5 (KIF11), exhibits anticancer potential by inducing cell cycle arrest and apoptosis throughFormule :C13H9F4NO2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :319.28(1S,3R,5R)-PIM447 dihydrochloride
(1S,3R,5R)-PIM447 (dihydrochloride) an inhibitor of PIM(IC50 of 0.095 μM for Pim1, 0.522 μM for Pim2 and 0.369 μM for Pim3).Formule :C24H25Cl2F3N4ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :513.38(±)-Enitociclib
CAS :(±)-Enitociclib ((±)-BAY-1251152) is a racemic mixture of BAY-1251152. BAY-1251152 is highly selective inhibitor of PTEF/CDK9.Formule :C19H18F2N4O2SDegré de pureté :99.29%Couleur et forme :SolidMasse moléculaire :404.43Ref: TM-T13467
1mg37,00€5mg88,00€10mg120,00€25mg216,00€50mg354,00€100mg567,00€200mg805,00€1mL*10mM (DMSO)87,00€CDK9 inhibitor HH1
CAS :CDK9 inhibitor HH1 (8019-9719) is an inhibitor of the human CDK2-cyclin A2 complex with an IC50 value of 2 μM.Formule :C13H15N3OSDegré de pureté :97.97%Couleur et forme :SolidMasse moléculaire :261.34RP-6306
CAS :Lunresertib (RP-6306) is a potent, selective, and orally active PKMYT1 inhibitor with an IC50 of 14 nM.Cost-effective and quality-assured.Formule :C18H20N4O2Degré de pureté :98.41% - 99.28%Couleur et forme :SolidMasse moléculaire :324.38CDK2 degrader 3
CAS :CDK2 degrader3 selectively degrades CDK2 and exhibits antitumor activity.Formule :C44H53ClN10O6SCouleur et forme :SolidMasse moléculaire :885.47Lerociclib
CAS :Lerociclib (G1T38) is a CDK4/6 inhibitor with anticancer and antitumor activities, inhibiting CDK4/CyclinD1 and CDK6/CyclinD3.Formule :C26H34N8ODegré de pureté :99%Couleur et forme :SolidMasse moléculaire :474.6360A
CAS :360A is a stabilizing G-Quadruplex ligand, and also inhibits telomerase activity for telomerase in TRAP-G4 assay(IC50 : 300 nM).Formule :C27H23N5O2Degré de pureté :98.68%Couleur et forme :SolidMasse moléculaire :449.5Apcin
CAS :Apcin: potent APC/C(Cdc20) E3 ligase inhibitor, blocks substrate recognition & mitosis, synergizes with Ts-Arg-OMe.Formule :C13H14Cl3N7O4Degré de pureté :96.74%Couleur et forme :SolidMasse moléculaire :438.65Ref: TM-T8561
1mg48,00€2mg63,00€5mg87,00€10mg140,00€25mg274,00€50mg472,00€100mg710,00€1mL*10mM (DMSO)97,00€Rosnilimab
CAS :Rosnilimab is a humanized IgG1-κ antibody that targets PD-1 [1] [2].Degré de pureté :98%Couleur et forme :LiquidEHop-016
CAS :EHop-016 is a specific Rac GTPase inhibitor with IC50 of 1.1 μM for Rac1 in MDA-MB-231 and MDA-MB-435 cells, equally effective inhibition for Rac3.Formule :C25H30N6ODegré de pureté :100% - 99.86%Couleur et forme :SolidMasse moléculaire :430.55Ref: TM-T2427
5mg48,00€10mg73,00€25mg127,00€50mg213,00€100mg334,00€200mg492,00€500mg787,00€1mL*10mM (DMSO)52,00€YJ1206
CAS :YJ1206 is a highly potent and selective CDK12/13 PROTAC degrader oral, DNA damage and cell-cycle arrest,and inhibits the proliferation of prostate cancer cells.Formule :C49H52FN11O5Degré de pureté :97.14%Couleur et forme :SolidMasse moléculaire :894.01MBM-17S
CAS :MBM-17S, a potent NIMA-related kinase 2 (Nek2) inhibitor with an IC50 of 3 nM, effectively inhibits cancer cell proliferation by inducing cell cycle arrest andFormule :C36H40N6O10Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :716.74WRN inhibitor 2
CAS :WRN Inhibitor 2 (example 118), a potent inhibitor of the WRN (Werner Syndrome ATP-dependent helicase enzyme), exhibits a pIC50 value of 7.0 or greater [1].Formule :C15H11F3N2O5S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :420.38DMT-dG(ib) Phosphoramidite
CAS :DMT-dG(ib) Phosphoramidite can be used to synthesize DNA.Formule :C44H54N7O8PDegré de pureté :99.74%Couleur et forme :SolidMasse moléculaire :839.92SU-9516
CAS :SU9516 is a selectively potent ATP-competitive inhibitor of CDKs.Formule :C13H11N3O2Degré de pureté :99.59%Couleur et forme :SolidMasse moléculaire :241.25Ref: TM-T8819
1mg90,00€5mg131,00€10mg170,00€25mg248,00€50mg321,00€100mg419,00€500mg938,00€1mL*10mM (DMSO)117,00€Aaptamine
CAS :Aaptamine functions as a proteasome inhibitor, it activates p21 promoter in a p53-independent manner.Formule :C13H12N2O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :228.25c-Myc inhibitor 11
c-Myc inhibitor 11 (Compound 67e), a c-MYC inhibitor (p EC 50 : 6.4), exhibits high clearance, a moderate volume of distribution, and a short half-life in ratFormule :C20H22N6ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :362.43AI-10-49
CAS :AI-10-49 is a selective inhibitor of the binding of CBFβ-SMMHC to RUNX1 with IC50 of 260 nM.Formule :C30H22F6N6O5Degré de pureté :97.14%Couleur et forme :SolidMasse moléculaire :660.52Ref: TM-T6753
2mg40,00€5mg60,00€10mg96,00€25mg169,00€50mg245,00€100mg361,00€200mg512,00€1mL*10mM (DMSO)88,00€SR15006
CAS :SR15006 is Krüppel-like factor 5 (KLF5) inhibitor (IC50 = 41.6 nM).Formule :C16H20ClN3O4SDegré de pureté :99.78%Couleur et forme :SoildMasse moléculaire :385.87Ref: TM-T60037
5mg39,00€10mg64,00€25mg117,00€50mg212,00€100mg316,00€200mg454,00€1mL*10mM (DMSO)62,00€SB-743921 hydrochloride
CAS :SB-743921 hydrochloride (SB743921 HCl) is an effective inhibitor of kinesin spindle protein, KSP, (Ki =0.1 nM).Formule :C31H34Cl2N2O3Degré de pureté :95.58% - 99.70%Couleur et forme :SolidMasse moléculaire :553.52Ref: TM-T2255
1mg42,00€5mg106,00€10mg163,00€25mg278,00€50mg429,00€100mg657,00€500mg1.501,00€1mL*10mM (DMSO)130,00€13-TP
13-TP is an inhibitor of SARS-CoV-2. It effectively suppresses in vitro RNA synthesis catalyzed by the central replication-transcription complex (C-RTC, nsp12-nsp7-nsp82) of SARS-CoV-2. 13-TP fully inhibits RdRp polymerase activity and obstructs the complete extension of some primer RNAs.Formule :C12H19F2N6O12P3Couleur et forme :SolidMasse moléculaire :570.23DL-Alanosine
CAS :DL-Alanosine is an amino acid analog with antitumor activity.Formule :C3H7N3O4Couleur et forme :SolidMasse moléculaire :149.105Caracemide
CAS :Caracemide (NSC-253272) inhibits the enzyme ribonucleotide reductase of Escherichia coli. Caracemide can be used in anticancer studies.Formule :C6H11N3O4Degré de pureté :98.81%Couleur et forme :SolidMasse moléculaire :189.17AURKA against 1
Compound Ac13, also termed AURKA against 1, acts as an inhibitor of the Aurora kinase (AURKA) with an IC50 of less than 0.5 nM, targeting the acetylation of endogenous lysine (K162) and exhibiting anti-tumor cell proliferation activity. The kinase activity of AURKA, acetylated at K162 and induced by AURKA against 1, is reversibly restored in HCT116 cells transfected with SIRT3.Formule :C28H32FN9O2Couleur et forme :SolidMasse moléculaire :545.61PD-1-IN-17
CAS :PD-1-IN-17 is an inhibitor of programmed cell death-1 (PD-1). PD-1-IN-17 inhibits 92% splenocyte proliferation at 100 nM.Formule :C13H22N6O7Degré de pureté :99.6%Couleur et forme :SolidMasse moléculaire :374.35PD-L1-IN-2
CAS :PD-L1-IN-2, a Naamidine J derivative, serves as a promising antineoplastic immunomodulator by hindering PD-L1 activity.Formule :C33H38N4O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :586.68Laromustine
CAS :Laromustine (VNP40101M) is a sulfonyl hydrolysis alkylation prodrug for cancer treatment with significant anticancer activity, inhibiting thioredoxin reductase.Formule :C6H14ClN3O5S2Couleur et forme :SolidMasse moléculaire :307.785-Fluorouridine 5'-phosphate
CAS :5-Fluorouridine 5'-phosphate acts as an ODCase (uridine 5'-monophosphate decarboxylase) inhibitor, exhibiting a Ki value of 98 µM for human ODCase and 645 µM for Methanococcus jannaschii ODCase. This compound also shows inhibitory activity on leukemia and lymphoma cell lines, making it useful for cancer research studies.Formule :C9H12FN2O9PCouleur et forme :SolidMasse moléculaire :342.172AS2863619 free base
CAS :AS2863619 free base enables the conversion of antigen-specific effector/memory T cells into Foxp3+ regulatory T (Treg) cells.Formule :C16H12N8OCouleur et forme :SolidMasse moléculaire :332.32KB-0742 dihydrochloride
CAS :KB-0742 dihydrochloride is a potent, selective and orally inhibitor of CDK9.Formule :C16H27Cl2N5Degré de pureté :99.79%Couleur et forme :SolidMasse moléculaire :360.33Ref: TM-T9446
1mg96,00€2mg143,00€5mg235,00€10mg378,00€25mg630,00€50mg898,00€100mg1.216,00€1mL*10mM (DMSO)249,00€2-Keto-D-galactose
CAS :2-Keto-D-galactose inhibits DNA synthesis and inhibits the proliferation of in vitro grown Ehrlich ascites tumor cells.Formule :C6H10O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :178.14Zn(BQTC)
CAS :Zn(BQTC) inhibits mtDNA and nDNA, damages mitochondria/nuclei, triggers apoptosis, and targets A549R cancer cells.Formule :C30H36Cl2N5O3ZnDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :650.92Ocifisertib(CFI-400945 free base)
CAS :Ocifisertib (CFI-400945 free base) is a potent, selective and orally active inhibitor of polo-like kinase 4.Cost-effective and quality-assured.Formule :C33H34N4O3Degré de pureté :97.56% - 98.53%Couleur et forme :SolidMasse moléculaire :534.65ATN-161 trifluoroacetate salt
CAS :ATN-161 TFA salt, a new integrin α5β1 inhibitor, curbs angiogenesis, liver metastases growth, enhances survival in mice.Formule :C25H36F3N9O10SDegré de pureté :98% - 99.98%Couleur et forme :SolidMasse moléculaire :711.67Eciruciclib
CAS :Eciruciclib is an inhibitor of CDK with antitumor properties.Formule :C27H33FN8Degré de pureté :97.51%Couleur et forme :SolidMasse moléculaire :488.6IBR2
CAS :IBR2 is a potent RAD51 inhibitor that disrupts DNA repair, inhibits cancer cell growth, and induces apoptosis.Formule :C24H20N2O2SDegré de pureté :96.15%Couleur et forme :SolidMasse moléculaire :400.49Ref: TM-T11600
1mg35,00€5mg70,00€10mg111,00€25mg183,00€50mg259,00€100mg359,00€200mg532,00€1mL*10mM (DMSO)77,00€Tirofiban
CAS :Tirofiban (L700462) (MK-383) is a selective palate GPIIb/IIIa antagonist which inhibits platelet aggregation with IC50 of 9 nM.Formule :C22H36N2O5SDegré de pureté :99.87%Couleur et forme :SolidMasse moléculaire :440.6Enoxacin
CAS :Enoxacin (NSC-629661) is a broad-spectrum 6-fluoronaphthyridinone antibacterial agent (fluoroquinolones) structurally related to nalidixic acid.Formule :C15H17FN4O3Degré de pureté :98.68% - 99.89%Couleur et forme :Off-White To Yellow CrystalsMasse moléculaire :320.32