Récepteur des glucocorticoïdes
Le récepteur des glucocorticoïdes (GR) est un récepteur hormonal nucléaire qui médie les effets des glucocorticoïdes, une classe d'hormones stéroïdes impliquées dans la régulation du métabolisme, de la réponse immunitaire et du stress. Les agonistes et antagonistes du récepteur des glucocorticoïdes sont largement utilisés dans le traitement des maladies inflammatoires et auto-immunes, ainsi que dans la thérapie contre le cancer. Les modulateurs du GR sont également des outils importants pour étudier les rôles physiologiques et pathologiques des glucocorticoïdes. Chez CymitQuimica, nous offrons une large gamme de modulateurs du récepteur des glucocorticoïdes de haute qualité pour soutenir vos recherches en endocrinologie, immunologie et régulation hormonale.
Produits appartenant à la catégorie "Récepteur des glucocorticoïdes"
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Medrysone
CAS :Medrysone is a synthetic glucocorticoid for topical use with anti-inflammatory and anti-allergic effects, altering gene expression to reduce inflammation.Formule :C22H32O3Degré de pureté :97.72% - 99.91%Couleur et forme :SolidMasse moléculaire :344.49Prednisolone hemisuccinate
CAS :Prednisolone hemisuccinate is a soluble glucocorticoid and cortisol exerts anti-inflammatory, immunosuppressive, and antiallergic by binding to GR receptor.Formule :C25H32O8Degré de pureté :99.96%Couleur et forme :SolidMasse moléculaire :460.52Dexamethasone acetate
CAS :Dexamethasone acetate (NSC 39471) is a potent anti-inflammatory steroid, blocks NF-kB, and lacks salt-retention.Formule :C24H31FO6Degré de pureté :99.22% - 99.65%Couleur et forme :White Or Almost White Crystalline PowderMasse moléculaire :434.5GSK9027
CAS :GSK9027, a nonsteroidal GR agonist, is a partial 2×GRE reporter gene activator, less potent than dexamethasone.Formule :C27H19F4N3O2SDegré de pureté :99.36%Couleur et forme :SolidMasse moléculaire :525.52N-Demethyl Mifepristone
CAS :N-Demethyl Mifepristone (RU 42633), an active metabolite of Mifepristone, exhibits 61% of the affinity for the glucocorticoid receptor relative to Mifepristone'Formule :C28H33NO2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :415.57Apararenone
CAS :Apararenone (MT-3995) is a receptor antagonist of mineralocorticoid receptor which can be used to treat non-alcoholic steatohepatitis and diabetic nephropathy.Formule :C17H17FN2O4SDegré de pureté :99.65%Couleur et forme :SolidMasse moléculaire :364.3922-Hydroxy mifepristone
CAS :22-Hydroxy Mifepristone (RU 42698) is an orally active hydroxylated alcohol metabolite that exhibits both anti-progestational and anti-glucocorticoid activities. This compound contains an alkyne group and is capable of undergoing copper-catalyzed azide-alkyne cycloaddition (CuAAC) with azide-containing molecules. Furthermore, 22-Hydroxy Mifepristone demonstrates a relative binding affinity of 48% to the human glucocorticoid receptor.Formule :C29H35NO3Couleur et forme :SolidMasse moléculaire :445.59Prednisolone acetate
Prednisolone acetate (Omnipred) is the acetate salt form of prednisolone, a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties.Formule :C23H30O6Degré de pureté :98.26% - 98.85%Couleur et forme :White Crystalline PowderMasse moléculaire :402.48Fluticasone furoate
CAS :Fluticasone furoate (Avamys), a potent, trifluorinated steroid with anti-inflammatory effects, treats allergic rhinitis.Formule :C27H29F3O6SDegré de pureté :99.58%Couleur et forme :SolidMasse moléculaire :538.58Ref: TM-T21404
4g2.663,00€5mg35,00€10mg52,00€25mg92,00€50mg137,00€100mg187,00€200mg279,00€500mg472,00€1mL*10mM (DMSO)58,00€Mifepristone
CAS :Mifepristone (C-1073) is a Progestin Antagonist. The mechanism of action of mifepristone is as a Progestational Hormone Receptor Antagonist.Formule :C29H35NO2Degré de pureté :98.9% - ≥95%Couleur et forme :Pale Yellow SolidMasse moléculaire :429.59Fluocinolone (Acetonide)
CAS :Fluocinolone Acetonide (Flucort-N) is a glucocorticoid derivative used topically in the treatment of various skin disorders.Formule :C24H30F2O6Degré de pureté :99.29% - 99.66%Couleur et forme :Crystals From Acetone & Hexane SolidMasse moléculaire :452.49Miricorilant
CAS :Miricorilant (CORT 118335) is a glucocorticoid receptor modulator for the study of digestive and metabolic disorders.Formule :C24H23F3N2O2Degré de pureté :98.62%Couleur et forme :SolidMasse moléculaire :428.45Fludrocortisone acetate
CAS :Fludrocortisone acetate (9α-Fludrocortisone acetate) , a glucocorticoid-receptor agonist, binds to cytoplasmic receptors, translocates to the nucleus, andFormule :C23H31FO6Degré de pureté :96.92% - 98.03%Couleur et forme :Crystalline SolidMasse moléculaire :422.49Dexamethasone palmitate
CAS :DXP, a lipophilic prodrug of Dexamethasone, has 47x less glucocorticoid receptor affinity; it's an agonist & anti-inflammatory.Formule :C38H59FO6Degré de pureté :98.08%Couleur et forme :SolidMasse moléculaire :630.87Triamcinolone hexacetonide
CAS :Triamcinolone hexacetonide, an exogenous synthetic corticosteroid, is a GR agonist used in the study of auto-reactive pericarditis and diabetic macular edema.Formule :C30H41FO7Degré de pureté :99.57%Couleur et forme :SolidMasse moléculaire :532.64Amcinonide
CAS :Amcinonide (CL-34699) is a Corticosteroid. The mechanism of action of amcinonide is as a Corticosteroid Hormone Receptor Agonist.Formule :C28H35FO7Degré de pureté :98.33% - 99.62%Couleur et forme :SolidMasse moléculaire :502.57Budesonide
CAS :Budesonide (Pulmicort), an anti-inflammatory corticosteroid, has shown the effective glucocorticoid activitie and few mineralocorticoid activities. According to reports, Budesonide has extensively inhibitory effects against multiple cells types and mediators referred to allergic and nonallergic-mediated inflammatory. What's more, the anti-inflammatory action of budesonide has been revealed to contribute to the effectiveness of asthma.Formule :C25H34O6Degré de pureté :99.03% - 99.72%Couleur et forme :Crystals SolidMasse moléculaire :430.53Cortisone acetate
CAS :Cortisone Acetate is a synthetic or semisynthetic analog of the naturally occurring cortisone hormone produced by the adrenal glands with anti-inflammatory andFormule :C23H30O6Degré de pureté :98.63% - 99.73%Couleur et forme :SolidMasse moléculaire :402.48Corticosterone
CAS :Corticosterone (Kendall's compound B) is an adrenocortical steroid with salocorticoid and glucocorticoid activity that is orally active.Formule :C21H30O4Degré de pureté :97.25% - ≥95%Couleur et forme :SolidMasse moléculaire :346.46Prednisolone
CAS :Prednisolone (Hydroretrocortine) is a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties.Formule :C21H28O5Degré de pureté :99.59% - 99.85%Couleur et forme :Crystals SolidMasse moléculaire :360.44
