
NF-κB
Le facteur nucléaire kappa B (NF-κB) est un facteur de transcription qui régule l'expression des gènes impliqués dans les réponses immunitaires, l'inflammation, la survie cellulaire et la prolifération. Le NF-κB est activé en réponse à divers stimuli, y compris les cytokines, les agents pathogènes et les signaux de stress. La dérégulation de la signalisation du NF-κB est associée à des maladies inflammatoires chroniques, au cancer et aux troubles auto-immuns. Chez CymitQuimica, nous offrons une sélection complète de modulateurs de la voie NF-κB pour soutenir vos recherches en inflammation, oncologie et régulation immunitaire.
Produits appartenant à la catégorie "NF-κB"
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PI-1840
CAS :PI-1840 is a reversible and selective chymotrypsin-like (CT-L) inhibitor, with little proteasome proteolytic effects on trypsin-like (T-L) and PGPH-L.Formule :C22H26N4O3Degré de pureté :98.82%Couleur et forme :SolidMasse moléculaire :394.47Geranylgeraniol
CAS :Geranylgeraniol (FT0626663) is an isoprenoid found in fruits, vegetables, and grains, including rice.Formule :C20H34ODegré de pureté :99.89% - ≥98%Couleur et forme :SolidMasse moléculaire :290.48Triacetylresveratrol
CAS :Triacetylresveratrol (Acetyl-trans-resveratrol) has anti-cancer activity, it inhibits the phosphorylation of STAT3 and NFκB in pancreatic cancer cells.Formule :C20H18O6Degré de pureté :99.81%Couleur et forme :Off White PowderMasse moléculaire :354.35Suberosin
CAS :Suberosin: anti-inflammatory, anticoagulant, deters Aedes aegypti bites, potential mosquito larvicide.Formule :C15H16O3Degré de pureté :97.08% - 99.12%Couleur et forme :SolidMasse moléculaire :244.298-Deoxygartanin
CAS :8-Deoxygartanin is a butyrylcholinesterase (BChE) selective inhibitor, it exhibits significant inhibition of self-induced α2-amyloid (Aα2) aggregation, it hasFormule :C23H24O5Degré de pureté :99.04% - 99.76%Couleur et forme :SolidMasse moléculaire :380.43Madecassic acid
CAS :Madecassic acid (L-fucopyranose) is extracted from the whole herb of Centella asiatica.Formule :C30H48O6Degré de pureté :98.80% - 99.69%Couleur et forme :SolidMasse moléculaire :504.7Anti-osteoporosis agent-4
Anti-osteoporosis agent-4 (Compound 11h) suppresses the differentiation of primary osteoclasts and attenuates RANKL-induced osteoclastogenesis.Formule :C26H26ClN3O7SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :560.02QNZ
CAS :QNZ (EVP4593) (EVP4593) is an effective inhibitor of NF-κB activation and TNF-α production. The IC50 of QNZ for NF-κB and TNF-α is11 nM and 7 nM, respectively.Formule :C22H20N4ODegré de pureté :98.16% - 99.17%Couleur et forme :White SolidMasse moléculaire :356.42Ref: TM-T6204
1mg43,00€2mg57,00€5mg93,00€10mg140,00€25mg226,00€50mg329,00€100mg490,00€1mL*10mM (DMSO)93,00€IKKγ NBD Inhibitory Peptide acetate
IKKγ NBD Inhibitory Peptide acetate is a NEMO-binding domain peptide (NBD peptide) acetate corresponding to the NEMO amino-terminal alpha-helical region.Degré de pureté :99.15%Couleur et forme :SolidMasse moléculaire :N/ARef: TM-TP1615L
1mg131,00€2mg173,00€5mg255,00€10mg374,00€25mg625,00€50mg890,00€100mg1.206,00€500mg2.422,00€IKK-IN-1
CAS :IKK-IN-1 is an inhibitor of IKK.Formule :C22H26ClN3O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :431.91Okanin
CAS :Okanin shows significant activities on both linoleic acid peroxidation inhibition and DPPH radical scavenging effect.Formule :C15H12O6Degré de pureté :95.19% - 99.4%Couleur et forme :SolidMasse moléculaire :288.25Ref: TM-TN2008
1mg88,00€5mg259,00€10mg311,00€25mg525,00€50mg750,00€100mg1.017,00€1mL*10mM (DMSO)217,00€RIP1 kinase inhibitor 7
CAS :RIP1 Kinase Inhibitor 7 (Compound 41) serves as a potent inhibitory agent for receptor interacting protein 1 kinase (RIP1) with an IC50 of under 100 nM.Formule :C20H20FN3ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :337.39Barlerin
CAS :Barlerin (8-O-Acetylshanzhiside methyl ester) has potential against cerebral ischemic injury, and protective effect on oxygen-glucose deprivation-induced injuryFormule :C19H28O12Degré de pureté :99.83% - ≥95%Couleur et forme :SolidMasse moléculaire :448.42Ref: TM-T5S1632
1mg40,00€2mg52,00€5mg85,00€10mg115,00€25mg245,00€50mg354,00€100mg533,00€1mL*10mM (DMSO)92,00€14-Deoxy-11,12-didehydroandrographolide
CAS :14-Deoxy-11,12-didehydroandrographolide (AP10) has hypotensive, anti-inflammatory, anti-asthma, and anti-cancer actions. It can inhibit NF-κB activation.Formule :C20H28O4Degré de pureté :98.55% - 99.93%Couleur et forme :SolidMasse moléculaire :332.43Ref: TM-TQ0185
1mg69,00€5mg187,00€10mg274,00€25mg465,00€50mg677,00€100mg938,00€500mg1.882,00€1mL*10mM (DMSO)145,00€SP-100030
CAS :SP-100030: Strong NF-κB/AP-1 inhibitor, IC50=50 nM. Reduces IL-2, IL-8, TNF-alpha, and murine CIA.Formule :C14H5ClF9N3ODegré de pureté :99.57%Couleur et forme :SolidMasse moléculaire :437.65Ref: TM-T24816
1mg35,00€5mg73,00€10mg104,00€25mg243,00€50mg378,00€100mg542,00€500mgÀ demander1mL*10mM (DMSO)82,00€RIPK1-IN-25
RIPK1-IN-25 (WL8) is a RIPK1 inhibitor with blood-brain barrier permeability, displaying an EC50 of 19.9 nM and a Kd of 25 nM. It is utilized in the research of neurodegenerative diseases.Couleur et forme :Odour SolidGanoderic acid H
CAS :Ganoderic acid H inhibits AP-1/NF-κB, suppressing uPA to exert antitumor effects.Formule :C32H44O9Degré de pureté :95% - 97.14%Couleur et forme :SolidMasse moléculaire :572.69Galloylpaeoniflorin
CAS :Galloylpaeoniflorin (6'-O-Galloyl paeoniflorin) may be developed as a cytoprotector against ROS-mediated oxidative stress.Formule :C30H32O15Degré de pureté :97.1%Couleur et forme :SolidMasse moléculaire :632.57Necrostatin 2 racemate
CAS :Necrostatin 2 racemate (Necrostatin-2 racemate) is an potent and specific inhibitor of RIPK1.Formule :C13H12ClN3O2Degré de pureté :98% - 99.50%Couleur et forme :SolidMasse moléculaire :277.71Ref: TM-T7504
1mg65,00€5mg107,00€10mg169,00€25mg305,00€50mg527,00€100mg743,00€500mg1.510,00€1mL*10mM (DMSO)140,00€Bortezomib
CAS :Bortezomib (LDP 341) is a 20S proteasome inhibitor (Ki=0.6 nM) that is reversible and selective.Formule :C19H25BN4O4Degré de pureté :100% - 99.97%Couleur et forme :Yellow SolidMasse moléculaire :384.24Ref: TM-T2399
5mg52,00€10mg64,00€25mg80,00€50mg96,00€100mg144,00€200mg225,00€500mg373,00€1mL*10mM (DMSO)52,00€