MAPK
Les MAPK sont une famille de kinases protéiques impliquées dans une variété de processus cellulaires, y compris la croissance, la prolifération, la différenciation et les réponses au stress. La voie de signalisation MAPK comprend plusieurs niveaux, y compris ERK, JNK et p38 MAPK, chacun jouant des rôles distincts dans la fonction cellulaire. La dérégulation de la signalisation MAPK est liée au cancer, aux maladies inflammatoires et aux troubles métaboliques. Chez CymitQuimica, nous offrons un large éventail d'inhibiteurs et d'activateurs de MAPK pour soutenir vos recherches en biologie cellulaire, transduction de signaux et mécanismes des maladies.
Produits appartenant à la catégorie "MAPK"
Trier par
PD318088
CAS :PD318088 is a non-ATP competitive allosteric MEK1/2 inhibitor, binding simultaneously with ATP in a region of the MEK1 active site that is adjacent to the ATP-Formule :C16H13BrF3IN2O4Degré de pureté :99.81%Couleur et forme :SolidMasse moléculaire :561.09Casein kinase 1δ-IN-27
CAS :Casein kinase1δ-IN-27 (Compound 8) is an inhibitor of casein kinase 1 (CK1), effectively inhibiting CK1α, CK1δ, CK1ε, and p38α with IC50 values of 22, 16.5, 9.41, and 14.8 nM, respectively. It also suppresses DUX4 expression, with an IC50 of 10 nM.Formule :C21H19FN6Couleur et forme :SolidMasse moléculaire :374.414Lucidenic acid D
CAS :Lucidenic acid D2 is a nartural product from G. lucidum AF.Formule :C29H38O8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :514.61Rhoifolin
CAS :Rhoifolin (Apigenin 7-O-neohesperidoside) is extracted from Turpinia arguya Seem dried leaves.Formule :C27H30O14Degré de pureté :98.11% - 98.87%Couleur et forme :SolidMasse moléculaire :578.52APS6-45
CAS :APS6-45 inhibits RAS/MAPK signaling and exhibits anti-tumor activity.Formule :C23H16F8N4O3Degré de pureté :99.39%Couleur et forme :SolidMasse moléculaire :548.39Ref: TM-T8843
2mg39,00€5mg88,00€10mg127,00€25mg250,00€50mg401,00€100mg615,00€200mg830,00€1mL*10mM (DMSO)97,00€HS220
CAS :HS220 is an inhibitor of TAK1 which plays a key role in the signaling pathways of inflammation and cell survival.Formule :C18H17N3O3Degré de pureté :99.98%Couleur et forme :SoildMasse moléculaire :323.35Ref: TM-T60011
1mg49,00€5mg110,00€10mg170,00€25mg280,00€50mg373,00€100mg510,00€200mg700,00€1mL*10mM (DMSO)116,00€Nedometinib
CAS :Nedometinib (NFX-179) is a MEK1 inhibitor with anticancer and antitumor activities, which can be used to study malignant tumors.Formule :C17H16FIN4O3Degré de pureté :99.18%Couleur et forme :SolidMasse moléculaire :470.24Ref: TM-T78209
1mg74,00€5mg159,00€10mg226,00€25mg373,00€50mg593,00€100mg785,00€200mg1.035,00€1mL*10mM (DMSO)165,00€S6K-18
CAS :S6K-18, a highly selective S6K1 inhibitor, inhibits S6K1 with IC50 of 52nM.Formule :C17H18N4O3SDegré de pureté :98.99%Couleur et forme :SolidMasse moléculaire :358.41Desoxo-narchinol A
CAS :Desoxo-narchinol A exhibits protective effects against LPS-induced endotoxin shock and inflammation through p38 deactivation, it shows inhibitory activityFormule :C12H16O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :192.25PF-06260933
CAS :PF-06260933 is a highly selective small-molecule MAP4K4 inhibitor with IC50s of 3.7 and 160 nM for kinase and cell, respectively.Formule :C16H13ClN4Degré de pureté :99.63% - 99.97%Couleur et forme :SolidMasse moléculaire :296.75Ref: TM-T4221
1mg49,00€2mg64,00€5mg103,00€10mg163,00€25mg324,00€50mg520,00€100mg750,00€1mL*10mM (DMSO)103,00€PAF (C16)
CAS :PAF (C16) is a potent MAPK and MEK/ERK activator that induces increased vascular permeability.Formule :C26H54NO7PDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :523.68QL-X-138 HCl
QL-X-138 HCl is a BTK/MNK dual kinase inhibitor with anticancer activity and anti-dengue virus 2 activity that inhibits BTK, MNK1, and MNK2 kinases.Formule :C25H20ClN5O2Degré de pureté :98.89%Couleur et forme :SoildMasse moléculaire :457.91Locostatin
CAS :Locostatin is a potent and cell permeable inhibitor of Raf kinase inhibitor protein (RKIP)/Raf1 kinase interaction and an inhibitor of cell migration.Formule :C14H15NO3Degré de pureté :97.13%Couleur et forme :SolidMasse moléculaire :245.27PRT062607 hydrochloride
CAS :PRT062607 hydrochloride (P505-15 Hydrochloride) is a selective inhibitor of Syk. PRT062607 displays at least 80-fold selectivity for Syk over other kinases.Formule :C19H23N9O·HClDegré de pureté :97.11% - 99.93%Couleur et forme :SolidMasse moléculaire :429.91Ref: TM-T2696
1mg60,00€2mg86,00€5mg127,00€10mg187,00€25mg326,00€50mg500,00€200mg948,00€1mL*10mM (DMSO)139,00€Bisabolangelone
CAS :Bisabolangelone: anti-tumor, anti-inflammatory, anti-microbial, antioxidant, blocks MAPK/NF-κB in dendritic cells.Formule :C15H20O3Degré de pureté :98.91%Couleur et forme :SolidMasse moléculaire :248.3215-Methoxypinusolidic acid
CAS :15-Methoxypinusolidic acid: anti-inflammatory, inhibits iNOS/NO, affects MAPK/NF-kappaB, stops adipogenesis and glutamate toxicity, induces apoptosis.Formule :C21H30O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :362.46Agerafenib
CAS :Agerafenib (CEP32496) is a highly potent inhibitor of BRAF.Formule :C24H22F3N5O5Degré de pureté :95.78% - 99.23%Couleur et forme :SolidMasse moléculaire :517.46Ref: TM-T2070
1mg42,00€5mg87,00€10mg131,00€25mg230,00€50mg378,00€100mg560,00€200mg800,00€1mL*10mM (DMSO)96,00€BAY-6035
CAS :BAY-6035 is an inhibitor of SET and MYND domain-containing protein 3 (SMYD3). BAY-6035 has more than 100-fold selectivity over other histone methyltransferases.Formule :C22H28N4O3Degré de pureté :99.39%Couleur et forme :SolidMasse moléculaire :396.48Avicularin
CAS :Avicularin reduces inflammation via ERK pathway in RAW 264.7 cells and hinders lipid buildup in adipocytes by limiting glucose uptake and fatty acid synthesis.Formule :C20H18O11Degré de pureté :97.02% - 99.94%Couleur et forme :White PowderMasse moléculaire :434.35Ref: TM-T6S0117
1mg58,00€5mg97,00€10mg160,00€25mg283,00€50mg418,00€100mg615,00€200mg878,00€1mL*10mM (DMSO)111,00€Pan-RAS-IN-1
CAS :Pan-RAS-IN-1 is an inhibitor of pan-Ras. It disrupts the interaction of Ras proteins and their effectors.Formule :C36H41Cl2F3N6O2Degré de pureté :98.57%Couleur et forme :SolidMasse moléculaire :717.65Ref: TM-T16432
1mg80,00€2mg97,00€5mg144,00€10mg216,00€25mg439,00€50mg660,00€100mg938,00€500mg1.882,00€1mL*10mM (DMSO)221,00€
