Facteur Xa
Le facteur Xa est une enzyme cruciale dans la cascade de coagulation qui convertit la prothrombine en thrombine, entraînant la formation de caillots sanguins. L'inhibition du facteur Xa est une stratégie thérapeutique largement utilisée pour prévenir et traiter les troubles thromboemboliques, tels que la thrombose veineuse profonde, l'embolie pulmonaire et l'AVC. Chez CymitQuimica, nous proposons des inhibiteurs du facteur Xa pour soutenir vos recherches en hématologie, santé cardiovasculaire et thérapie anticoagulante.
Produits appartenant à la catégorie "Facteur Xa"
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Betrixaban maleate
CAS :"Betrixaban, a non-vitamin K anticoagulant by Portola, inhibits factor Xa with low hERG affinity, preventing VTE in at-risk adults."Formule :C27H26ClN5O7Degré de pureté :99.46% - 99.86%Couleur et forme :SolidMasse moléculaire :567.98cMCoFx1
CAS :cMCoFx1 is an effective and selective FXIIa cyclic peptide inhibitor. It exhibits high binding affinity for FXIIa (KD: 900 pM) and potent inhibitory activity (Ki: 370 pM). cMCoFx1 effectively suppresses the intrinsic coagulation pathway, demonstrates high stability in serum, and shows no cytotoxicity.Formule :C146H232N52O44S6Couleur et forme :SolidMasse moléculaire :3612.12Betrixaban
CAS :Betrixaban is a non-VKORC1 anticoagulant targeting factor Xa, with low hERG affinity, used to prevent VTE in adults with mobility issues.Formule :C23H22ClN5O3Degré de pureté :99.35%Couleur et forme :SolidMasse moléculaire :451.91Ref: TM-T4341
2mg47,00€5mg70,00€10mg96,00€25mg167,00€50mg283,00€100mg454,00€500mg998,00€1mL*10mM (DMSO)77,00€Denecimig
CAS :Denecimig (Mim8) is a bispecific and humanized IgG4κ antibody, hemophilia A, activated coagulation factors IXa (FIXa) and X (FX) arresting bleeding.Degré de pureté :95%Couleur et forme :LiquidHeparin sodium salt
CAS :Heparin sodium, a sulfated glycosaminoglycan, acts as an anticoagulant and inhibits exosome-cell interactions.Formule :C26H42N2NaO37S5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1157.89Coumarin
CAS :Coumarin: plant-based poison found in tonka beans, woodruff, bison grass; used to make anticoagulants like warfarin.Formule :C9H6O2Degré de pureté :98.89%Couleur et forme :White Solid CrystallineMasse moléculaire :146.14Rivaroxaban-d4
CAS :Rivaroxaban-d4 is a deuterated marker of Rivaroxaban for isotopic tracing.BAY 59-7939 is a potent and selective direct inhibitor of coagulation factor Xa (FXa.Formule :C19H18ClN3O5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :439.91Betrixaban hydrochloride(330942-05-7(free base))
Betrixaban hydrochloride(330942-05-7(free base)) (PRT054021 hydrochloride) is a potent, selective, and orally efficacious factor Xa (fXa) inhibitor (IC50: 1.5Formule :C23H23Cl2N5O3Degré de pureté :99.54%Couleur et forme :SolidMasse moléculaire :488.36Ref: TM-T4690
1mg48,00€2mg60,00€5mg97,00€10mg154,00€25mg338,00€50mg520,00€100mg748,00€1mL*10mM (DMSO)106,00€Ethyl 1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate
CAS :Ethyl 1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl) compound inhibits coagulation factor Xa, useful for thrombotic conditions study.Formule :C27H28N4O5Degré de pureté :99.55%Couleur et forme :SolidMasse moléculaire :488.54Zifaxaban
CAS :Zifaxaban (TY-602) is an oral selective factor Xa inhibitor with an IC50 of 11.1 nM, highly specific over other serine proteases, used in thrombosis studies.Formule :C20H16ClN3O4SDegré de pureté :97.46% - 99.42%Couleur et forme :SolidMasse moléculaire :429.88Ref: TM-T29215
1mg333,00€5mg787,00€10mg1.074,00€25mg1.510,00€50mg1.882,00€100mg2.375,00€500mg4.655,00€O-Desmethyl apixaban sulfate sodium
O-Desmethyl apixaban sulfate sodium inhibits factor X (FXa) with a Ki of 58 μM,and is a major circulating metabolite of Apixaban in humans.Formule :C24H22N5NaO7SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :547.52Darexaban
CAS :Darexaban (YM-150) selectively inhibits Factor Xa, reducing clotting and risk of heart/stroke events.Formule :C27H30N4O4Degré de pureté :98.33%Couleur et forme :SolidMasse moléculaire :474.55Ref: TM-T31206
1mg48,00€5mg95,00€10mg144,00€25mg235,00€50mg354,00€100mg512,00€200mg727,00€1mL*10mM (DMSO)92,00€Benzamidine hydrochloride
CAS :Benzamidine hydrochloride (Benzamidine HCl) is a reversible inhibitor of serine proteases, including trypsin, plasmin, and thrombin.Formule :C7H9ClN2Degré de pureté :99.25% - 99.97%Couleur et forme :White To Off-White PowderMasse moléculaire :156.61Letaxaban
CAS :Letaxaban (TAK-442) is a small molecule Xa factor inhibitor that can be used to study polar coronary syndromes and thrombotic blockages.Formule :C22H26ClN3O5SDegré de pureté :98.68% - 99.01%Couleur et forme :SolidMasse moléculaire :479.98Enoxaparin sodium
CAS :Enoxaparin, a low-weight heparin approved by FDA for STEMI, enhances antithrombin and prevents clotting by inhibiting factors XIa, IXa, Xa, IIa.Formule :C42H59N3Na4O35S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1322Edoxaban Tosylate Monohydrate
CAS :Edoxaban(DU-176) is an oral factor Xa (FXa) inhibitor in clinical development for stroke prevention.Formule :C31H40ClN7O8S2Degré de pureté :99.86% - 99.91%Couleur et forme :SolidMasse moléculaire :738.27EMD-503982
CAS :EMD-503982 is a potential Factor Xa and Factor VIIa inhibitor with anticancer activity for the study of thromboembolic and neurologic diseases.Formule :C22H23ClN4O5Degré de pureté :98.44% - 99.12%Couleur et forme :SolidMasse moléculaire :458.90Apixaban
CAS :Apixaban (BMS-562247-01) is an orally active inhibitor of coagulation factor Xa with anticoagulant activity.Formule :C25H25N5O4Degré de pureté :99.73% - 99.93%Couleur et forme :SolidMasse moléculaire :459.5Asundexian
CAS :Asundexian (BAY-2433334) is a potent and orally active inhibitor of the coagulation factor FXIa that directly and reversibly binds to the active site of FXIa,Formule :C26H21ClF4N6O4Degré de pureté :100% - 99.90%Couleur et forme :SolidMasse moléculaire :592.935-R-Rivaroxaban
CAS :5-R-Rivaroxaban is the (R)-enantiomer of Rivaroxaban, a potent FXa inhibitor with IC50 0.7 nM and Ki 0.4 nM.Formule :C19H18ClN3O5SDegré de pureté :99.75%Couleur et forme :SolidMasse moléculaire :435.88
