Cellules souche et Dérivés
Les inhibiteurs de cellules souches sont des composés qui ciblent spécifiquement les voies de signalisation et les protéines impliquées dans le maintien, la différenciation et la prolifération des cellules souches. Ces inhibiteurs sont cruciaux pour comprendre la biologie des cellules souches et pour développer des stratégies visant à manipuler les cellules souches à des fins thérapeutiques, telles que la médecine régénérative et le traitement du cancer. En contrôlant le destin des cellules souches, ces inhibiteurs peuvent aider à orienter la différenciation des cellules souches en types cellulaires spécifiques ou à prévenir une croissance cellulaire indésirable. Chez CymitQuimica, nous offrons une sélection d'inhibiteurs de cellules souches de haute qualité pour soutenir vos recherches en biologie des cellules souches, biologie du développement et médecine régénérative.
Sous-catégories appartenant à la catégorie "Cellules souche et Dérivés"
- Gamma-sécrétase
- Hérisson/Smoothened
- Voie de signalisation Hippo
- JAK
- Porc-épic
- ROCK
- STAT
- Cellules souches
- TGF-beta/Smad
- Wnt/beta-caténine
Affichez 2 plus de sous-catégories
Produits appartenant à la catégorie "Cellules souche et Dérivés"
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iCRT 14
CAS :iCRT 14 is a novel potent inhibitor of β-catenin-responsive transcription (CRT)(IC50= 40.3 nM in assays of Wnt pathway activity).Formule :C21H17N3O2SDegré de pureté :98.85% - 99.8%Couleur et forme :SolidMasse moléculaire :375.44IQ 1
CAS :IQ 1 has multiple roles, such as maintaining the multifunctionality of mouse ESCs, decreasing Wnt-stimulated phosphorylation, blocking PP2A/Nkd interactions.Formule :C21H22N4O2Degré de pureté :98.57% - ≥95%Couleur et forme :SolidMasse moléculaire :362.42Ref: TM-T3635
5mg51,00€10mg78,00€25mg140,00€50mg195,00€100mg350,00€200mg500,00€500mg810,00€1mL*10mM (DMSO)57,00€WHI-P97
CAS :WHI-P97 is a rationally designed potent inhibitor of JAK-3.Formule :C16H13Br2N3O3Degré de pureté :99.93%Couleur et forme :SolidMasse moléculaire :455.1CDK8-IN-11
CAS :CDK8-IN-11 is a CDK8 inhibitor that demonstrates anti-proliferative activity against colon cancer cell lines and inhibits the activation of WNT/β-catenin.Formule :C19H15F3N4O2Degré de pureté :99.74%Couleur et forme :SolidMasse moléculaire :388.34Ref: TM-T61742
1mg59,00€5mg127,00€10mg205,00€25mg454,00€50mg748,00€100mg1.054,00€200mg1.415,00€1mL*10mM (DMSO)139,00€ROCK2-IN-2
CAS :ROCK2-IN-2 is a selective inhibitor of ROCK2 (IC50 of <1 μM).Formule :C18H12N6OSDegré de pureté :98.45%Couleur et forme :SolidMasse moléculaire :360.39Ref: TM-T12747
1mg52,00€5mg117,00€10mg187,00€25mg320,00€50mg472,00€100mg730,00€200mg938,00€1mL*10mM (DMSO)143,00€(Rac)-SIS3 free base
CAS :SIS3 free base is a potent and selective Smad3 phosphorylation inhibitor. SIS3 free base inhibits the myofibroblast differentiation of fibroblasts by TGF-β1.Formule :C28H27N3O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :453.53YAP/TAZ inhibitor-2
CAS :Potent oral TEAD-YAP/TAZ inhibitor-2 with 3 nM EC50; exhibits anti-proliferative and antitumor effects.Formule :C19H14F4N4ODegré de pureté :98.84%Couleur et forme :SoildMasse moléculaire :390.33Ref: TM-T60218
1mg92,00€2mg119,00€5mg187,00€10mg298,00€25mg502,00€50mg725,00€100mg1.017,00€500mg2.023,00€1mL*10mM (DMSO)207,00€IWR-1
CAS :IWR-1 (IWR-1-endo), a Wnt pathway inhibitor, stabilizes the Axin destruction complex(EC50=0.2 uM).Formule :C25H19N3O3Degré de pureté :98.46% - 99.82%Couleur et forme :SolidMasse moléculaire :409.44IWP 12
CAS :IWP 12 is a potent inhibitor of porcupine (Porcn), blocking Wnt signaling and inhibiting fin regeneration in adult and juvenile fish.Formule :C18H18N4O2S3Degré de pureté :98.88%Couleur et forme :SolidMasse moléculaire :418.56JBJ-02-112-05
CAS :JBJ-02-112-05 is a potent, mutant-selective, allosteric and orally active inhibitor of EGFR with an IC 50 of 15 nM for EGFR L858R/T790M [1].Formule :C27H20N4O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :464.54Mouse TNC(Tenascin C) ELISA Kit
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse TNC. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse TNC. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Mouse TNC, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Mouse TNC in the samples is then determined by comparing the OD of the samples to the standard curve.Couleur et forme :Colourless TransparentliquidNetarsudil Dihydrochloride
CAS :Netarsudil Dihydrochloride (AR-13324 Dihydrochloride) is an inhibitor of Rho-related protein kinase (ROCK) and norepinephrine transporter (NET) and is effective in reducing intraocular pressure (IOP).Cost-effective and quality-assured.Formule :C28H29Cl2N3O3Degré de pureté :99.94% - 99.98%Couleur et forme :SolidMasse moléculaire :526.45LF3
CAS :LF3 is a specific inhibitor of canonical Wnt signaling by disrupting the interaction between β-catenin and TCF4 (IC50 < 2 μM)Formule :C20H24N4O2S2Degré de pureté :99.63%Couleur et forme :SolidMasse moléculaire :416.56MRT-10
CAS :MRT-10 is a Smoothened (Smo) receptor antagonist.Formule :C24H23N3O5SDegré de pureté :99.47%Couleur et forme :SolidMasse moléculaire :465.52Ref: TM-T23027
1mg47,00€2mg63,00€5mg96,00€10mg135,00€25mg265,00€50mg378,00€100mg530,00€200mg720,00€1mL*10mM (DMSO)87,00€GDC-9918
CAS :GDC-9918 (compound GDC-9918) is an inhibitor of Janus kinases.Formule :C20H18F2N6O5SCouleur et forme :SolidMasse moléculaire :492.46JAK3-IN-15
JAK3-IN-15 (compound 22) is a JAK3 inhibitor that reduces the secretion of p-JAK3 induced by LPS. It is utilized in research for rheumatoid arthritis.Couleur et forme :Odour SolidFM-381
CAS :FM381, a JAK3 inhibitor with 127 pM IC50, is 410-3600x more selective over JAK1/2/TYK2.Formule :C24H24N6O2Degré de pureté :98.44%Couleur et forme :SolidMasse moléculaire :428.49CJJ300
CAS :CJJ300 is a TGF-β inhibitor disrupting TGF-β-TβR complex formation, with an IC50 of 5.3 μM, and halts cell migration.Formule :C30H33N3Degré de pureté :99.41%Couleur et forme :SolidMasse moléculaire :435.6Ref: TM-T62483
2mg35,00€5mg51,00€10mg90,00€25mg164,00€50mg259,00€100mg393,00€200mg552,00€1mL*10mM (DMSO)57,00€BDP9066
CAS :BDP9066 is a potent and selective MRCK inhibitor, inhibits MRCKβ and MRCKα/β, and can be used for the prevention and treatment of skin cancer.Formule :C20H24N6Degré de pureté :98.18%Couleur et forme :SolidMasse moléculaire :348.44Ref: TM-T14521
1mg57,00€5mg120,00€10mg188,00€25mg432,00€50mg747,00€100mg1.293,00€500mg2.585,00€1mL*10mM (DMSO)133,00€WDR5-0103 hydrochloride[890190-22-4(free base)]
WDR5-0103 hydrochloride[890190-22-4(free base)] (WD-Repeat Protein 5-0103) is an effective and specific WD repeat-containing protein 5 (WDR5) antagonist (Kd:Formule :C21H26ClN3O4Degré de pureté :99.66%Couleur et forme :SolidMasse moléculaire :419.9
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