c-Fms
Les inhibiteurs de c-Fms ciblent le récepteur du facteur de stimulation des colonies-1 (c-Fms), une tyrosine kinase impliquée dans la régulation des macrophages et d'autres cellules immunitaires. La signalisation de c-Fms joue un rôle dans la prolifération, la différenciation et la survie de ces cellules. La dérégulation de c-Fms est associée à des maladies telles que le cancer, les conditions inflammatoires et l'ostéoporose. Chez CymitQuimica, nous proposons des inhibiteurs de c-Fms pour soutenir vos recherches en immunologie, oncologie et maladies inflammatoires.
Produits appartenant à la catégorie "c-Fms"
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CSF1R Protein, Human, Recombinant (His & Avi), Biotinylated
CSF1R Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag.Couleur et forme :Lyophilized PowderMasse moléculaire :57.76 kDa (predicted); 82.52 kDa (reducing conditions)c-Fms-IN-2
CAS :c-Fms-IN-2 is an inhibitor of c-FMS kinase (IC50 = 24 nM).Formule :C19H21N3O3Degré de pureté :97.34%Couleur et forme :SolidMasse moléculaire :339.39Ref: TM-T10775
1mg96,00€5mg255,00€10mg375,00€25mg562,00€50mg792,00€100mg1.064,00€1mL*10mM (DMSO)190,00€Anti-CSF1R Antibody (5B661)
Anti-CSF1R Antibody (5B661) is a Mouse antibody targeting CSF1R. Anti-CSF1R Antibody (5B661) can be used in ELISA,ELISA(Cap).Couleur et forme :Odour Liquidc-Fms-IN-6
CAS :c-Fms-IN-6 is a potent inhibitor of c-FMS (IC50 ≤10 nM for unphosphorylated c-FMS) and also weakly inhibits unphosphorylated c-KIT and PDGFR (IC50: > 1 μM).Formule :C22H25N7O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :419.48CSF1R Protein, Human, Recombinant
CSF1R Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 55.1 kDa and the accession number is P07333-1.Couleur et forme :Lyophilized PowderMasse moléculaire :55.1 kDa (predicted); 80-90 kDa (reducing condition, due to glycosylation)CSF1R Protein, Human, Recombinant (mFc)
CSF1R Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag.Couleur et forme :Lyophilized PowderMasse moléculaire :81.5 kDa (predicted)c-Fms-IN-13
CAS :c-Fms-IN-13 (compound 14) is a potent FMS kinase inhibitor (IC50= 17 nM). c-Fms-IN-13 is an anti-inflammatory agent.Formule :C22H26N4O2Degré de pureté :100% - 99.83%Couleur et forme :SolidMasse moléculaire :378.47Lacnotuzumab
CAS :Lacnotuzumab (MCS110) is a humanized monoclonal antibody targeting CSF-1, which can be used in research on retinal diseases.Degré de pureté :>95%Couleur et forme :LiquidCSF1R Protein, Human, Recombinant (His & GST)
CSF1R Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag.Couleur et forme :Lyophilized PowderMasse moléculaire :76 kDa (predicted); 75 kDa (reducing conditions)Lenzilumab
CAS :Lenzilumab (KB 003) is a humanized GM-CSF neutralizing antibody for the study of COVID-19.Degré de pureté :95% - 95%Couleur et forme :LiquidCSF1R Protein, Cynomolgus, Recombinant (His)
M-CSFR/CSF1R/CD115 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag.Couleur et forme :Lyophilized PowderMasse moléculaire :56.3 kDa (predicted). Due to glycosylation, the protein migrates to 75-105 kDa based on Tris-Bis PAGE result.PLX5622
CAS :PLX5622 is a selective, orally active and blood-brain barrier permeable CSF1R inhibitor. PLX5622 induces elimination of microglia. Cost effective and quality assured.Formule :C21H19F2N5ODegré de pureté :98% - 99.89%Couleur et forme :SolidMasse moléculaire :395.41Ref: TM-T7100
5mg96,00€10mg158,00€25mg308,00€50mg510,00€100mg617,00€500mg1.311,00€1mL*10mM (DMSO)94,00€Gimsilumab
CAS :Gimsilumab (MORAb-022) is an anti-c-Fms humanized monoclonal antibody for the study of inflammation and hypoxemia caused by COVID-19.Degré de pureté :99.49% (SEC-HPLC) - 99.49% (SEC-HPLC)Couleur et forme :LiquidMasse moléculaire :145.8 kDaCSF1R-IN-17
CSF1R-IN-17 (compound 9) is a potent, selective antagonist of CSF1R, exhibiting an inhibition concentration half-maximum (IC50) of 0.2 nM.Formule :C20H25N5O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :367.44Pimicotinib
CAS :Pimicotinib (ABSK021) is a potent CSF1R inhibitor with antitumor activity and can be used to study advanced solid tumors.Formule :C22H24N6O3Degré de pureté :99.8%Couleur et forme :SolidMasse moléculaire :420.46CSF1R Protein (Ala299-Glu512), Human, Recombinant (His)
CSF1R Protein (Ala299-Glu512), Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.Couleur et forme :Lyophilized PowderMasse moléculaire :25.3 kDa (predicted)Edicotinib
CAS :Edicotinib (JNJ-527) is a blood-brain permeable, selective CSF-1R inhibitor, with lesser inhibitory effects on KIT and FLT3.Cost-effective and quality-assured.Formule :C27H35N5O2Degré de pureté :98.58% - 99.69%Couleur et forme :SolidMasse moléculaire :461.6Emactuzumab
CAS :Emactuzumab(RG 7155) is a monoclonal antibody against colony-stimulating factor-1 receptor targeting tumor-associated macrophages (TAMs) Emactuzumab hasDegré de pureté :SDS-PAGE:98.3%;SEC-HPLC:97.3%Couleur et forme :LiquidMasse moléculaire :144.4 kDaAnti-CSF1R Antibody (8O797)
Anti-CSF1R Antibody (8O797) is a Mouse antibody targeting CSF1R. Anti-CSF1R Antibody (8O797) can be used in ELISA.Couleur et forme :Odour LiquidAnti-CSF1R Antibody-FITC (4Y587)
Anti-CSF1R Antibody-FITC (4Y587) is a FITC-conjugated Mouse antibody targeting CSF1R. Anti-CSF1R Antibody-FITC (4Y587) can be used in FCM.Couleur et forme :Odour Liquid
