Autophagie
Les inhibiteurs de l'autophagie ciblent le processus cellulaire de l'autophagie, qui implique la dégradation et le recyclage des composants cellulaires via les lysosomes. L'autophagie est un mécanisme crucial pour maintenir l'homéostasie cellulaire, mais sa dérégulation est impliquée dans diverses maladies, y compris le cancer, les maladies neurodégénératives et les infections. Les inhibiteurs de l'autophagie peuvent bloquer ce processus, ce qui en fait des outils précieux pour étudier le rôle de l'autophagie dans les maladies et développer des stratégies thérapeutiques. Chez CymitQuimica, nous proposons des inhibiteurs de l'autophagie pour soutenir vos recherches en biologie cellulaire, oncologie et maladies neurodégénératives.
Produits appartenant à la catégorie "Autophagie"
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AZD 6482
CAS :AZD 6482 (KIN-193) is a potent and selective inhibitor of p110β and PI3Kβ with IC50 values of 0.69nM and 10nM.Cost-effective and quality-assured.Formule :C22H24N4O4Degré de pureté :99.79% - 99.95%Couleur et forme :SolidMasse moléculaire :408.45ML-SA5
CAS :ML-SA5 is a MCOLN1 agonist that blocks autophagic flux by disrupting fusion between autophagosomes and lysosomes.Cost-effective and quality-assured.Formule :C19H24ClN3O4S2Degré de pureté :100.00% - 99.16%Couleur et forme :SoildMasse moléculaire :457.99IU1
CAS :IU1 是一种可逆的特异性人类 USP14 蛋白酶体抑制剂,可以穿透细胞,IC50为 4.7 μM。Formule :C18H21FN2ODegré de pureté :98% - 99.30%Couleur et forme :SolidMasse moléculaire :300.37Pitavastatin calcium
CAS :Pitavastatin calcium (NK-104), a inhibitor of HMG-CoA reductase, lowers both total cholesterol and low-density lipoprotein cholesterol in animals and humans.Formule :C50H46CaF2N2O8Degré de pureté :100% - 99.49%Couleur et forme :White To Off-White PowderMasse moléculaire :880.98Dapivirine
CAS :Dapivirine (R147681) is a diarylpyrimidine non-nucleoside reverse transcriptase inhibitor.Formule :C20H19N5Degré de pureté :98% - 99.77%Couleur et forme :SolidMasse moléculaire :329.4Acumapimod
CAS :Acumapimod (BCT-197) is an orally active inhibitor of p38α MAPK (IC50 <1 μM).Formule :C22H19N5O2Degré de pureté :≥95%Couleur et forme :SolidMasse moléculaire :385.42Tazarotene
CAS :Tazarotene (Zorac), a synthetic topical retinoid, treats psoriasis by normalizing keratinocytes and reducing growth.Formule :C21H21NO2SDegré de pureté :97.01% - 99.14%Couleur et forme :White SolidMasse moléculaire :351.46Ref: TM-T6696
5mg38,00€10mg49,00€25mg88,00€50mg147,00€100mg256,00€200mg334,00€500mg563,00€1mL*10mM (DMSO)55,00€BI-D1870
CAS :BI-D1870 is a highly specific, blood-brain-permeable, and ATP-competitive inhibitor of the N-terminal AGC kinase domain of RSK.Cost-effective and quality-assured.Formule :C19H23F2N5O2Degré de pureté :98.51% - 99.43%Couleur et forme :SolidMasse moléculaire :391.42Ref: TM-T6171
1mg52,00€2mg78,00€5mg137,00€10mg207,00€25mg335,00€50mg472,00€100mg658,00€500mg1.378,00€1mL*10mM (DMSO)117,00€Mevastatin
CAS :Mevastatin (ML236B) is an HMG-CoA reductase inhibitor that was initially isolated from the mold Pythium ultimum.Formule :C23H34O5Degré de pureté :99.12%Couleur et forme :White-Yellowish To Yellow Powder Solid PowderMasse moléculaire :390.51Tezacaftor
CAS :Tezacaftor (VX661) is a small molecule that can be used as a corrector of the cystic fibrosis transmembrane conductance regulator (CFTR) gene function.Formule :C26H27F3N2O6Degré de pureté :100% - 99.69%Couleur et forme :SolidMasse moléculaire :520.5Ref: TM-T2263
1mg40,00€2mg52,00€5mg82,00€10mg123,00€25mg212,00€50mg343,00€100mg505,00€1mL*10mM (DMSO)88,00€Albendazole
CAS :Albendazole (SKF-62979) is used as a drug indicated for the treatment of a variety of worm infestations.Formule :C12H15N3O2SDegré de pureté :98.21% - 98.76%Couleur et forme :Colorless Crystals SolidMasse moléculaire :265.33Entrectinib
CAS :Entrectinib (RXDX-101) is an orally Trk, ROS1, and ALK inhibitor. Entrectinib exhibits antitumor activity. Cost-effective and quality-assured.Formule :C31H34F2N6O2Degré de pureté :98.03% - 99.61%Couleur et forme :SolidMasse moléculaire :560.64Ref: TM-T3678
2mg42,00€5mg59,00€10mg88,00€25mg111,00€50mg168,00€100mg283,00€500mg692,00€1mL*10mM (DMSO)69,00€PI-103
CAS :PI-103 is a potent, cell-permeable, ATP-competitive inhibitor of PI3K family members (IC50s: 2/3/3/15/30/23 nM for p110α/β/δ/γ, mTOR, and DNA-PK).Formule :C19H16N4O3Degré de pureté :96.59% - 99.3%Couleur et forme :SolidMasse moléculaire :348.36Salinomycin sodium salt
CAS :Salinomycin sodium salt (Sodium salinomycin), an antibiotic potassium ionophore, is an effective inhibitor of Wnt/β-catenin signaling.Formule :C42H69NaO11Degré de pureté :98.76% - 99.11%Couleur et forme :White Or Light Yellow Crystalline Powder With Special SmelMasse moléculaire :772.98Resveratrol analog 1
CAS :Resveratrol analog 1 is a natural product analog of resveratrol, which has more significant anti-leukemic activity than resveratrol.Formule :C14H11FO2Degré de pureté :98.42%Couleur et forme :SolidMasse moléculaire :230.23PRIMA-1
CAS :PRIMA-1 (NSC-281668) is a mutant p53 reactivator. It induces apoptosis and inhibits growth of human tumors with mutant p53.Formule :C9H15NO3Degré de pureté :99.22%Couleur et forme :SolidMasse moléculaire :185.22Ref: TM-T6954
5mg51,00€10mg73,00€25mg140,00€50mg207,00€100mg368,00€200mg547,00€500mg877,00€1mL*10mM (DMSO)57,00€C646
CAS :C646, a histone acetyltransferase inhibitor, inhibits p300 (Ki: 400 nM, in a cell-free assay).Formule :C24H19N3O6Degré de pureté :98% - 99.21%Couleur et forme :SolidMasse moléculaire :445.42Bromhexine hydrochloride
CAS :Bromhexine hydrochloride (Bisolvon) is a mucolytic agent used in the treatment of respiratory disorders associated with viscid or excessive mucus.Formule :C14H21Br2ClN2Degré de pureté :99.98%Couleur et forme :White SolidMasse moléculaire :412.59ALLO-1
CAS :ALLO-1, vital for autophagy, aids in engulfing paternal organelles by binding to worm LC3, LGG-1, via its LIR motif.Formule :C17H15ClN2O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :314.77Pemetrexed
CAS :Pemetrexed (LY-231514 Disodium Hydrate), a guanine-derived antineoplastic agent, binds to and inhibits the enzyme thymidylate synthase (TS).Formule :C20H21N5O6Degré de pureté :98.1% - 99.92%Couleur et forme :Similar To White PowderMasse moléculaire :427.413,3'-Diindolylmethane
CAS :3,3'-Diindolylmethane (DIM), a small molecule compound, is a proposed Y preventive agent.Formule :C17H14N2Degré de pureté :100%Couleur et forme :SolidMasse moléculaire :246.31Peretinoin
CAS :Peretinoin (NIK333) is an oral acyclic retinoid with a vitamin A-like structure that targets retinoid nuclear receptors such as RXR and RAR.Formule :C20H30O2Degré de pureté :97.23%Couleur et forme :SolidMasse moléculaire :302.45Ref: TM-TQ0064
1mg40,00€2mg51,00€5mg88,00€10mg126,00€25mg230,00€50mg401,00€100mg597,00€500mg1.283,00€1mL*10mM (DMSO)87,00€Tenovin-1
CAS :Tenovin-1 inhibits protein-deacetylating activities of SirT1 and SirT2 and protects against MDM2-mediated p53 degradation, which involves ubiquitination.Formule :C20H23N3O2SDegré de pureté :99.33%Couleur et forme :SolidMasse moléculaire :369.48Sevelamer hydrochloride
CAS :Sevelamer hydrochloride (Sevelamer HCl) is a phosphate binding drug used to treat hyperphosphatemia via binding to dietary phosphate and prevents its absorptionFormule :(C3H7N·C3H5ClO·HCl)xDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :186.08NS1643
CAS :NS1643 is a potent human ether-a-go-go related gene (hERG) KV11.1 channel activator with EC50 of 10.5 μM.Formule :C15H10F6N2O3Degré de pureté :98.37% - 99%Couleur et forme :SolidMasse moléculaire :380.24Thioridazine hydrochloride
CAS :Thioridazine hydrochloride (Mellaril) , an antipsychotic drug, is used in the therapy of psychosis and schizophrenia and shows serotonin antagonism or D4Formule :C21H27ClN2S2Degré de pureté :99.55% - 99.55%Couleur et forme :White To Off-White SolidMasse moléculaire :407.04Luteolin
CAS :Luteolin (Luteolol) belongs to the flavonoid group of natural products and is a Nrf2 inhibitor, PDE inhibitor.Formule :C15H10O6Degré de pureté :96.61% - 98%Couleur et forme :SolidMasse moléculaire :286.24Bakuchiol
CAS :Bakuchiol: anti-tumor, anti-helminthic, DNA polymerase1 inhibitor, cytotoxic, and anti-bacterial, may prevent dental caries.Formule :C18H24ODegré de pureté :98.69% - 99.47%Couleur et forme :Brownish Yellow Liquid ViscousMasse moléculaire :256.38Pamapimod
CAS :Pamapimod (R1503) (R-1503, Ro4402257) is a novel, selective inhibitor of p38 mitogen-activated protein kinase.Formule :C19H20F2N4O4Degré de pureté :97.63% - 99.99%Couleur et forme :SolidMasse moléculaire :406.38Ref: TM-T6927
1mg56,00€5mg119,00€10mg187,00€25mg378,00€50mg605,00€100mg852,00€500mg1.700,00€1mL*10mM (DMSO)131,00€XRK3F2
CAS :XRK3F2 inhibits p62-ZZ, counters MM's Runx2 suppression in vitro, and prompts bone growth and remodeling in vivo with tumors.Formule :C23H24ClF2NO3Degré de pureté :98.75% - 98.91%Couleur et forme :SolidMasse moléculaire :435.89STF-31
CAS :STF-31 is an inhibitor of glucose transporter 1 (GLUT1) with IC50 of 1 μM.Formule :C23H25N3O3SDegré de pureté :99.55% - 99.98%Couleur et forme :SolidMasse moléculaire :423.53Ref: TM-T2363
1mg38,00€2mg50,00€5mg81,00€10mg113,00€25mg230,00€50mg437,00€100mg640,00€500mg1.349,00€1mL*10mM (DMSO)106,00€Reserpine
CAS :Reserpine, an alkaloid from Rauwolfia roots, depletes neurotransmitters, used in treating hypertension and psychosis, but side effects restrict use.Formule :C33H40N2O9Degré de pureté :98.85% - 99.81%Couleur et forme :White Or Pale Buff To Slightly Yellowish Powder With A Bitter Taste (Ntp 1992)Masse moléculaire :608.68Nifedipine
CAS :Nifedipine (Procardia) is a dihydropyridine calcium channel blocking agent.Formule :C17H18N2O6Degré de pureté :99.39% - 99.49%Couleur et forme :Yellow Crystals Physical Description Odorless Yellow Crystals Or Powder Tasteless (Ntp 1992)Masse moléculaire :346.33Vinorelbine ditartrate
CAS :Vinorelbine ditartrate (KW-2307) is a natural alkaloid and an anti-mitotic agent. Vinorelbine ditartrate has anti-tumor activity. Cost-effective and quality-assured.Formule :C45H54N4O8·2C4H6O6Degré de pureté :98% - 99.86%Couleur et forme :White To Off-White Crystalline PowderMasse moléculaire :1079.11Tomatidine
CAS :Tomatidine serves as an anti-inflammatory agent by inhibiting NF-κB and JNK signaling pathways.Formule :C27H45NO2Degré de pureté :98.38% - 99.98%Couleur et forme :SolidMasse moléculaire :415.65Proflavine Hemisulfate
CAS :Proflavine Hemisulfate (3,6-Diaminoacridine hemisulfate) is the hemisulfate salt of proflavine, an acridine-derived fluorescent contrast and disinfectant agent.Formule :C13H12N3O2S0Degré de pureté :99.55%Couleur et forme :Orange To Red PowderMasse moléculaire :258.29CGI-1746
CAS :CGI1746 is a potent and highly selective small-molecule Btk inhibitor with IC50 of 1.9 nM.Formule :C34H37N5O4Degré de pureté :97.69% - 97.88%Couleur et forme :SolidMasse moléculaire :579.69Aumitin
CAS :Aumitin inhibits autophagy (IC50: 0.12-0.24μM), targets complex I, and blocks mitochondrial respiration.Formule :C24H20ClN5ODegré de pureté :99.13%Couleur et forme :SolidMasse moléculaire :429.9Ref: TM-T14346
1mg65,00€5mg150,00€10mg219,00€25mg395,00€50mg552,00€100mg775,00€200mg1.026,00€1mL*10mM (DMSO)164,00€PD98059
CAS :PD98059 is an MEK inhibitor that inhibits MEK1 and MEK2 (IC50=2/50 μM) and is non-ATP-competitive.Formule :C16H13NO3Degré de pureté :100% - 99.66%Couleur et forme :Yellow SolidMasse moléculaire :267.28Ref: TM-T2623
5mg40,00€10mg52,00€25mg82,00€50mg106,00€100mg177,00€200mg264,00€500mg444,00€1mL*10mM (DMSO)58,00€NSC 185058
CAS :NSC 185058 is an inhibitor of ATG4B, a major cysteine protease. It also can attenuate the autophagic activity.Formule :C11H9N3SDegré de pureté :99.27%Couleur et forme :SolidMasse moléculaire :215.27Tubastatin A Hydrochloride
CAS :Tubastatin A Hydrochloride (TSA HCl) is an effective and specific HDAC6 inhibitor (IC50: 15 nM).Formule :C20H21N3O2·HClDegré de pureté :97.24% - 99.15%Couleur et forme :SolidMasse moléculaire :371.86Ezetimibe
CAS :Ezetimibe (SCH 58235) is a Dietary Cholesterol Absorption Inhibitor. The physiologic effect of ezetimibe is by means of Decreased Cholesterol Absorption.Formule :C24H21F2NO3Degré de pureté :97.28% - 99.97%Couleur et forme :SolidMasse moléculaire :409.43Ref: TM-T1593
1g283,00€10mg48,00€25mg62,00€50mg77,00€100mg87,00€200mg125,00€500mg197,00€1mL*10mM (DMSO)55,00€Latrepirdine dihydrochloride
CAS :Latrepirdine dihydrochloride (Dimebolin dihydrochloride) is an orally active, and neuroactive antagonist of multiple drug targets.Formule :C21H25N3·2HClDegré de pureté :98.45%Couleur et forme :SolidMasse moléculaire :392.37Irinotecan
CAS :Irinotecan (CPT-11), a camptothecin derivative, inhibits topoisomerase I, used for colorectal cancer treatment.Formule :C33H38N4O6Degré de pureté :100% - 99.92%Couleur et forme :SolidMasse moléculaire :586.68Indole-3-Glyoxylyl Chloride
CAS :Indole-3-glyoxylyl chloride (3-Indoleglyoxylyl chloride) can be used in chemical synthesis, such as bisindolylmaleimide.Formule :C10H6ClNO2Degré de pureté :99.72%Couleur et forme :Yellow To Orange Powder Or CrystalsMasse moléculaire :207.61Ref: TM-T0618
1mg97,00€2mg145,00€5mg235,00€10mg394,00€25mg825,00€50mg1.349,00€100mg2.175,00€1mL*10mM (DMSO)379,00€Urolithin A
CAS :Urolithin A is a metabolite of ellagic acid, which inhibits DNA synthesis and induces apoptosis and autophagy. Cost-effective and quality-assured.Formule :C13H8O4Degré de pureté :99.14% - 99.66%Couleur et forme :SolidMasse moléculaire :228.2Ref: TM-T7174
5mg49,00€10mg72,00€25mg130,00€50mg187,00€100mg320,00€200mg472,00€500mg753,00€1mL*10mM (DMSO)50,00€Peiminine
CAS :1. Peiminine (Raddeanine) is an effective inhibitor for lung inflammation and pulmonary fibrosis in a rat model of bleomycin-induced lung injury.Formule :C27H43NO3Degré de pureté :99.52% - ≥95%Couleur et forme :White PowderMasse moléculaire :429.64PF-543 hydrochloride
CAS :PF-543 hydrochloride (PF-543) inhibits SphK1 with a K(i) of 3.6 nM, is sphingosine-competitive and is more than 100-fold selective for SphK1 over the SphK2Formule :C27H32ClNO4SDegré de pureté :98.90% - 99.93%Couleur et forme :SolidMasse moléculaire :502.1SBI-0640756
CAS :SBI-0640756 (SBI-756) (SBI-756) is a first-in-class inhibitor that targets eIF4G1 and disrupts the eIF4F complex.Formule :C23H14ClFN2O2Degré de pureté :99.75%Couleur et forme :SolidMasse moléculaire :404.82Ref: TM-T5173
1mg39,00€5mg87,00€10mg140,00€25mg271,00€50mg386,00€100mg540,00€200mg735,00€1mL*10mM (DMSO)93,00€Topotecan hydrochloride
CAS :Topotecan hydrochloride (NSC609699) is an antineoplastic agent used to treat ovarian cancer.Formule :C23H24ClN3O5Degré de pureté :97.88% - 98.71%Couleur et forme :White Crystalline SolidMasse moléculaire :457.92Ref: TM-T1174
1g512,00€5mg35,00€10mg51,00€25mg80,00€50mg107,00€100mg144,00€500mg344,00€1mL*10mM (DMSO)55,00€AL 8697
CAS :AL 8697 is a selective p38α MAPK inhibitor (IC50 = 6 nM) with 14-fold selectivity over p38β (IC50 = 82 nM) and 300-fold selectivity over a panel of 91 kinases.Formule :C21H21F3N4ODegré de pureté :98.96% - 99.26%Couleur et forme :SolidMasse moléculaire :402.41Ref: TM-T10277
1mg70,00€5mg145,00€10mg207,00€25mg348,00€50mg495,00€100mg678,00€500mgÀ demander1mL*10mM (DMSO)169,00€Pterostilbene
CAS :Pterostilbene is extracted from Pterocarpus indicus.Formule :C16H16O3Degré de pureté :99.20%Couleur et forme :Off-White Crystalline PowderMasse moléculaire :256.3Lapatinib ditosylate monohydrate
CAS :Lapatinib ditosylate monohydrate: a drug for advanced breast cancer; may cause liver issues.Formule :C29H26ClFN4O4S·2(C7H8O3S)·H2ODegré de pureté :98% - 99.41%Couleur et forme :Colourless To Light-Yellow CrystalMasse moléculaire :943.47KM11060
CAS :KM11060 is a novel corrector of the F508del-CFTR trafficking defect, Correcting F508del-CFTR trafficking, increasing the amount of functional CFTR at the plasmaFormule :C19H17Cl2N3O2SDegré de pureté :98.86%Couleur et forme :SolidMasse moléculaire :422.33Salvianolic acid B
CAS :Salvianolic acid B (Dan Shen Suan B) is a water-soluble antioxidant from Salvia miltiorrhiza extract with antiplatelet aggregation and antithrombotic effects.Formule :C36H30O16Degré de pureté :99.76% - 99.86%Couleur et forme :Yellow SolidMasse moléculaire :718.61YM-201636
CAS :YM201636 (IC50=33 nM), a specific PIKfyve inhibitor, is less effective to p110α and insensitive to Fabl, which is yeast orthologue.Formule :C25H21N7O3Degré de pureté :93.28% - 98.3%Couleur et forme :SolidMasse moléculaire :467.48Ref: TM-T6110
1mg48,00€2mg64,00€5mg96,00€10mg173,00€25mg359,00€50mg562,00€100mg802,00€500mg1.644,00€1mL*10mM (DMSO)97,00€Ambroxol hydrochloride
CAS :Ambroxol hydrochloride (Mucosolvan) is a metabolite of BROMHEXINE that stimulates mucociliary action and clears the air passages in the respiratory tract.Formule :C13H18Br2N2O·HClDegré de pureté :99.70%Couleur et forme :White To Yellowish Crystalline PowderMasse moléculaire :414.56Dehydrocorydaline
CAS :1.Formule :C22H24NO4Degré de pureté :99.84%Couleur et forme :SolidMasse moléculaire :366.43Ref: TM-T5S2358
1mg57,00€2mg81,00€5mg111,00€10mg160,00€25mg263,00€50mg378,00€100mg558,00€200mg797,00€1mL*10mM (DMSO)123,00€PF-06447475
CAS :PF-06447475 is a highly effective, specific, brain penetrant LRRK2 inhibitor with IC0 of 3/11 nM for wild type LRRK2 and G2019S LRRK2 respectively.Formule :C17H15N5ODegré de pureté :98.61% - 99.62%Couleur et forme :SolidMasse moléculaire :305.33DC661
CAS :DC661 is a palmitoyl-protein thioesterase 1 (PPT1) inhibitor that acts as an anti-lysosomal agent by inhibiting autophagy, demonstrating anti-cancer activity.Formule :C31H39Cl2N5Degré de pureté :99.07%Couleur et forme :SolidMasse moléculaire :552.58Ref: TM-T5538
1mg80,00€2mg105,00€5mg188,00€10mg319,00€25mg545,00€50mg780,00€100mg1.074,00€1mL*10mM (DMSO)230,00€Olanzapine
CAS :Olanzapine (LY170053) is an atypical antipsychotic that is used currently in the treatment of schizophrenia and bipolar illness.Formule :C17H20N4SDegré de pureté :100% - ≥95%Couleur et forme :Yellowish Crystalline PowderMasse moléculaire :312.43sbp-7455
CAS :SBP-7455 potently inhibited ULK1/2 enzymatic activity in vitro and in cells, reduced the viability of TNBC cells and had oral bioavailability in mice.Formule :C16H17F3N4O2Degré de pureté :97.90% - 99.03%Couleur et forme :SolidMasse moléculaire :354.33Doxorubicin
CAS :Doxorubicin (Adriamycin) is a Topoisomerase II (Top2) inhibitor with antineoplastic activity.Formule :C27H29NO11Degré de pureté :99.31%Couleur et forme :Red Crystalline Solid SolidMasse moléculaire :543.52RITA
CAS :RITA (NSC-652287) forms DNA-DNA/protein cross-links without DNA breaks; disrupts p53/Mdm2 like nutlin-3.Formule :C14H12O3S2Degré de pureté :97.76% - 98.85%Couleur et forme :SolidMasse moléculaire :292.37Ref: TM-T1798
1mg35,00€2mg46,00€5mg66,00€10mg96,00€25mg188,00€50mg344,00€100mg509,00€200mg715,00€500mg1.093,00€1mL*10mM (DMSO)89,00€5-Azacytidine
CAS :5-Azacytidine (Ladakamycin) is a cytidine nucleoside analog, a DNA methylation inhibitor with specificity.Formule :C8H12N4O5Degré de pureté :99.31% - 99.79%Couleur et forme :Crystals From Methanol Physical Description White Crystalline Powder (Ntp 1992)Masse moléculaire :244.2(-)-Epigallocatechin
CAS :(-)-Epigallocatechin, the predominant flavonoid in green tea, possesses the unique ability to attach to unfolded native polypeptides, thereby inhibiting theirFormule :C15H14O7Degré de pureté :98.83% - 99.76%Couleur et forme :White PowderMasse moléculaire :306.27OSI-027
CAS :OSI-027 (ASP4786) is a selective and potent dual inhibitor of mTORC1 and mTORC2 with IC50 of 22 nM and 65 nM.Formule :C21H22N6O3Degré de pureté :97.42%Couleur et forme :SolidMasse moléculaire :406.44Ref: TM-T6319
1mg42,00€2mg52,00€5mg86,00€10mg138,00€25mg248,00€50mg389,00€100mg567,00€1mL*10mM (DMSO)88,00€FAAH inhibitor 1
CAS :FAAH inhibitor 1 (Benzothiazole analog 3) is an effective FAAH inhibitor with an IC50 of 18 nM.Formule :C24H23N3O3S3Degré de pureté :98.05%Couleur et forme :SolidMasse moléculaire :497.65Ref: TM-T11256
1mg52,00€5mg116,00€10mg182,00€25mg306,00€50mg442,00€100mg620,00€200mg835,00€1mL*10mM (DMSO)128,00€MW-150
CAS :MW-150 (MW01-18-150SRM) is a unique protein kinase inhibitor, is a selective, CNS penetrant, and orally active inhibitor of p38α MAPK with a Ki of 101 nM.Formule :C24H23N5Degré de pureté :97.35% - 99.27%Couleur et forme :SolidMasse moléculaire :381.47Ref: TM-T5494
1mg39,00€5mg96,00€10mg153,00€25mg305,00€50mg454,00€100mg655,00€500mg1.406,00€1mL*10mM (DMSO)114,00€Rosiglitazone maleate
CAS :Rosiglitazone maleate (BRL 49653) is an oral antidiabetic and potential anticancer agent.Formule :C22H23N3O7SDegré de pureté :99.33% - 99.51%Couleur et forme :Off-White SolidMasse moléculaire :473.5Pictilisib dimethanesulfonate
CAS :Pictilisib dimethanesulfonate (GDC-0941 2 MeSO3H salt) is a potent inhibitor of PI3Kα/δ with IC50 of 3 nM, with modest selectivity against p110β (11-fold) andFormule :C25H35N7O9S4Degré de pureté :99.63%Couleur et forme :SolidMasse moléculaire :705.85Bicyclol
CAS :Bicyclol is an oral anti-hepatitis drug, decreasing ALT/AST levels by 50% and inhibiting HBV/HCV, boosting efficacy with interferon/lamivudine/adefovir.Formule :C19H18O9Degré de pureté :99.48% - 99.88%Couleur et forme :SolidMasse moléculaire :390.34Ref: TM-T4121
5mg63,00€10mg88,00€25mg192,00€50mg354,00€100mg518,00€500mg1.111,00€1mL*10mM (DMSO)63,00€Vismodegib
CAS :Vismodegib (GDC-0449) is a hedgehog pathway inhibitor (IC50: 3 nM). It also inhibits P-gp (IC50: 3.0 μM), ABCG2 (IC50: 1.4 μM).Formule :C19H14Cl2N2O3SDegré de pureté :98% - 99.99%Couleur et forme :SolidMasse moléculaire :421.3URMC-099
CAS :URMC-099: oral, brain-accessible MLK/LRRK2 inhibitor; IC50 - MLK1/2/3/DLK: 19/42/14/150 nM, LRRK2: 11 nM.Formule :C27H27N5Degré de pureté :98.43% - 99.32%Couleur et forme :SolidMasse moléculaire :421.54Pinosylvin
CAS :Pinosylvin (5-Styrylresorcinol) induces autophagy via AMPK activation. Pinosylvin is likely to act as a pro-angiogenic factor.Formule :C14H12O2Degré de pureté :99.89% - 99.91%Couleur et forme :SolidMasse moléculaire :212.24Deferoxamine Mesylate
CAS :Deferoxamine Mesylate (DFOM) is an iron chelator and iron death inhibitor.Formule :C26H52N6O11SDegré de pureté :94.68% - 99.80%Couleur et forme :SolidMasse moléculaire :656.79Paclitaxel
CAS :Paclitaxel (Taxol) is a natural product and a microtubule polymer stabilizer.Formule :C47H51NO14Degré de pureté :98% - 99.92%Couleur et forme :White PowderMasse moléculaire :853.91Danthron
CAS :Danthron (Antrapurol) is a natural product, regulates glucose, and lipid metabolism by activating AMPK.Formule :C14H8O4Degré de pureté :99.97%Couleur et forme :Red Or Red-Yellow Needles Or Leaves (From Alcohol) Physical Description Orange Crystalline Powder Almost Odorless And Tasteless (Ntp 1992)Masse moléculaire :240.21PATULIN
CAS :Patulin (Claviform) is a mycotoxin produced by a variety of molds commonly found in rotting apples, including Aspergillus and Penicillium.Formule :C7H6O4Degré de pureté :99.91%Couleur et forme :Compact Prisms Or Thick Plates From Ether Or Chloroform White CrystallineMasse moléculaire :154.12Ref: TM-T3936
1mg79,00€5mg210,00€10mg349,00€25mgÀ demander50mgÀ demander100mg2.619,00€1mL*10mM (DMSO)120,00€CZC-25146
CAS :CZC-25146, a stable LRRK2 inhibitor, IC50: 4.76 nM (wild-type), 6.87 nM (G2019S).Formule :C22H25FN6O4SDegré de pureté :97.68%Couleur et forme :SolidMasse moléculaire :488.54Topotecan
CAS :Topotecan (NSC-609669) is a Topoisomerase I inhibitor,and is an antineoplastic agent used to treat ovarian cancer that works by inhibiting DNA topoisomerases.Formule :C23H23N3O5Degré de pureté :95.19% - 97.58%Couleur et forme :Light Yellow Needle Crystal Or Crystalline PowderMasse moléculaire :421.45Raloxifene hydrochloride
CAS :Raloxifene HCl treats postmenopausal osteoporosis, acts as estrogen on bone/cholesterol, and blocks it in breast/uterus.Formule :C28H28ClNO4SDegré de pureté :98% - 99.81%Couleur et forme :Light Yellow SolidMasse moléculaire :510.044FERULIC ACID METHYL ESTER
CAS :FERULIC ACID METHYL ESTER (Methyl ferulate) is a hydroxycinnamic acid that is abundant in plants. FERULIC ACID METHYL ESTER has antioxidant activities.Formule :C11H12O4Degré de pureté :99.66% - 99.95%Couleur et forme :SolidMasse moléculaire :208.21P62-mediated mitophagy inducer
CAS :P62-mediated mitophagy inducer (PMI) is a regulator of mitophagy .Formule :C14H9IN4O2Degré de pureté :98.96%Couleur et forme :SolidMasse moléculaire :392.15Ref: TM-T13809
1mg35,00€5mg70,00€10mg96,00€25mg202,00€50mg329,00€100mg527,00€200mg750,00€1mL*10mM (DMSO)81,00€Aloe emodin
CAS :Aloe emodin (Rhabarberone) is an interferon-inducing agent, for JEV (IC50=1 μg/mL) and EV71(IC50=0.33 μg/mL ).Formule :C15H10O5Degré de pureté :97.00%Couleur et forme :Orange SolidMasse moléculaire :270.24Oprozomib
CAS :Oprozomib inhibits 20S proteasome β5/LMP7, is orally available, and may have cancer-fighting properties. IC50: β5 - 36 nM; LMP7 - 82 nM.Formule :C25H32N4O7SDegré de pureté :98% - 99.87%Couleur et forme :SolidMasse moléculaire :532.61Tetrahydrocurcumin
CAS :Tetrahydrocurcumin (HZIV 81-2), a major metabolite of curcumin, has strong antioxidant and cardioprotective properties.Formule :C21H24O6Degré de pureté :99.37%Couleur et forme :Solid PowderMasse moléculaire :372.41GNE-7915
CAS :GNE-7915 is a highly potent, selective and brain-penetrable leucine-rich repeat kinase 2 (LRRK2) inhibitor.Formule :C19H21F4N5O3Degré de pureté :98% - ≥95%Couleur et forme :SolidMasse moléculaire :443.4Ref: TM-T1945
5mg47,00€10mg62,00€25mg114,00€50mg187,00€100mg316,00€200mg410,00€500mg680,00€1mL*10mM (DMSO)50,00€Arctigenin
CAS :(-)-Arctigenin ((-)-Arctigenin) is found in burdock.Formule :C21H24O6Degré de pureté :98% - 99.51%Couleur et forme :SolidMasse moléculaire :372.41Obeticholic Acid
CAS :Obeticholic Acid (6-ECDCA, INT-747) is a high-affinity, semisynthetic, bile acid-derived FXR agonist.Cost-effective and quality-assured.Formule :C26H44O4Degré de pureté :99.88% - 99.97%Couleur et forme :SolidMasse moléculaire :420.63Ref: TM-T1789
5mg48,00€10mg52,00€25mg82,00€50mg99,00€100mg163,00€200mg274,00€500mg505,00€1mL*10mM (DMSO)49,00€Berberine hydrogen sulphate
CAS :Berberine hydrogen sulphate, a plant alkaloid, has broad antimicrobial effects on bacteria, fungi, and protozoa.Formule :C20H19NO8SDegré de pureté :99% - 99.79%Couleur et forme :Yellow Crystals Off-White To Yellow PowderMasse moléculaire :433.43U0126-EtOH
CAS :U0126-EtOH (U0126 Ethanol) is a non-ATP competitive specific inhibitor of MEK1/2 (IC50: 0.07/0.06 μM).Formule :C18H16N6S2·C2H6ODegré de pureté :98.65% - 99.82%Couleur et forme :SolidMasse moléculaire :426.6Dasatinib monohydrate
CAS :Dasatinib monohydrate, an oral SRC-kinase inhibitor, counters imatinib-resistant chronic myeloid leukemia.Formule :C22H28ClN7O3SDegré de pureté :100% - 99.68%Couleur et forme :SolidMasse moléculaire :506.03MK-2206 dihydrochloride
CAS :MK-2206 dihydrochloride (MK-2206 2HCl) is a variant Akt inhibitor that inhibits Akt1, Akt2, and Akt3 (IC50=8/12/65 nM) with orally active, highly potent andFormule :C25H23Cl2N5ODegré de pureté :99.228% - 99.91%Couleur et forme :SolidMasse moléculaire :480.39Ref: TM-T1952
2mg35,00€5mg51,00€10mg70,00€25mg96,00€50mg144,00€100mg216,00€200mg354,00€500mg582,00€1mL*10mM (DMSO)56,00€SG31
SG31 is a potent activator of autophagy, exerting its effects through the AMPK/ULK1-dependent pathway.Formule :C26H37N6O8PCouleur et forme :SolidMasse moléculaire :592.58Notoginsenoside Fc
CAS :1. Notoginsenoside Fc has perfect anti-platelet aggregatory effect.Formule :C58H98O26Degré de pureté :99.22% - 99.94%Couleur et forme :SolidMasse moléculaire :1211.38Salbutamol hemisulfate
CAS :Salbutamol hemisulfate (Albuterol Sulfate) is a short-acting β2-adrenergic receptor agonist with an IC50 of 8.93 μM.Formule :C13H21NO3H2O4SDegré de pureté :99.35%Couleur et forme :White Or Almost White Odourless PowderMasse moléculaire :576.7HDAC-IN-62
HDAC-IN-62 (Compound 5), an HDAC inhibitor, exhibits IC50 values of 0.78, 1.0, and 1.2 μM for HDAC6, HDAC8, and HDAC11, respectively.Formule :C15H14N2O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :302.35PD-166866
CAS :PD-166866 is a selective FGFR tyrosine kinase inhibitor.Formule :C20H24N6O3Degré de pureté :98.29%Couleur et forme :SolidMasse moléculaire :396.44Amsacrine hydrochloride
CAS :Amsacrine hydrochloride (acridinyl anisidide hydrochloride) is topoisomerase II inhibitor , is used in the treatment of acute myelogenous leukemia.Formule :C21H20ClN3O3SDegré de pureté :99.05% - 99.92%Couleur et forme :SolidMasse moléculaire :429.92Dynasore
CAS :Dynasore, a cell-permeable dynamin inhibitor, blocks GTPase of dynamin 1/2 and Drp1 (IC50: 15 μM) without affecting other small GTPases.Formule :C18H14N2O4Degré de pureté :95.85% - 99.22%Couleur et forme :SolidMasse moléculaire :322.31Ref: TM-T1848
5mg49,00€10mg79,00€25mg140,00€50mg259,00€100mg374,00€200mg560,00€500mg883,00€1mL*10mM (DMSO)87,00€Piceatannol
CAS :Piceatannol (Astringenin) is a synthetic anti-inflammatory that blocks p56lck, syk kinases, and NF-κB, made from resveratrol.Formule :C14H12O4Degré de pureté :98.66% - 99.57%Couleur et forme :Light Tan To Yellow PowderMasse moléculaire :244.24Isoliquiritigenin
CAS :Isoliquiritigenin (ISL) is a natural flavonoid that inhibits influenza virus and aldose reductase. Isoliquiritigenin has antitumor effect. Cost-effective and quality-assured.Formule :C15H12O4Degré de pureté :97.61% - 99.44%Couleur et forme :PowderMasse moléculaire :256.25GNE0877
CAS :GNE0877 (GNE 0877) is a highly effective and specific leucine-rich repeat kinase 2 (LRRK2) inhibitor (Ki: 0.7 nM).Formule :C14H16F3N7Degré de pureté :98.01% - 99.96%Couleur et forme :SolidMasse moléculaire :339.32Ref: TM-T6031
1mg47,00€2mg60,00€5mg119,00€10mg187,00€25mg376,00€50mg562,00€100mg802,00€500mg1.644,00€1mL*10mM (DMSO)96,00€ZSTK474
CAS :PI3K Inhibitor ZSTK474 is an orally available, s-triazine derivative, ATP-competitive phosphatidylinositol 3-kinase (PI3K) inhibitor with potentialFormule :C19H21F2N7O2Degré de pureté :98.29% - 99.76%Couleur et forme :White PowderMasse moléculaire :417.41Skepinone-L
CAS :Skepinone-L (CBS3830) is a selective p38 mitogen-activated protein kinase inhibitor.Formule :C24H21F2NO4Degré de pureté :100% - 99.76%Couleur et forme :SolidMasse moléculaire :425.42Ref: TM-T6130
1mg38,00€2mg49,00€5mg79,00€10mg119,00€25mg208,00€50mg313,00€100mg465,00€1mL*10mM (DMSO)87,00€Rutin
CAS :Rutin (Quercetin 3-O-rutinoside), a flavonoid, has a variety of biological activities including antiallergic, anti-inflammatory, antiproliferative, andFormule :C27H30O16Degré de pureté :95.66% - 97.19%Couleur et forme :SolidMasse moléculaire :610.52Sirtinol
CAS :Sirtinol is a selective SIRT1/2 inhibitor (IC50: 131/38 μM).Formule :C26H22N2O2Degré de pureté :99.52% - 99.96%Couleur et forme :SolidMasse moléculaire :394.47Ref: TM-T6671
2mg43,00€5mg58,00€10mg93,00€25mg178,00€50mg343,00€100mg509,00€500mg1.121,00€1mL*10mM (DMSO)58,00€Cryptotanshinone
CAS :Cryptotanshinone: STAT3 inhibitor, IC50 4.6 μM; blocks STAT3 Tyr705 phosphorylation, minor effect on Ser727, no impact on STAT1/5.Formule :C19H20O3Degré de pureté :97.69% - ≥95%Couleur et forme :Orange Needle CrystalMasse moléculaire :296.36Dihydroartemisinin
CAS :Dihydroartemisinin (Artenimol) is a metabolite of artemisinin.Formule :C15H24O5Degré de pureté :99.41% - 99.72%Couleur et forme :White SolidMasse moléculaire :284.35Paeonol
CAS :Paeonol (Peonol) is an active extraction from Paeonia suffruticosa. Paeonol inhibits MAO-A and MAO-B with IC50 of 54.6 μM and 42.5 μM, respectively.Formule :C9H10O3Degré de pureté :98.55% - 99.56%Couleur et forme :White To Beige Crystalline PowderMasse moléculaire :166.17MK-5108
CAS :MK-5108 (VX-689) is a highly potent and specific Aurora-A kinase inhibitor with an IC50 value of 0.064 nM.Formule :C22H21ClFN3O3SDegré de pureté :100%Couleur et forme :SolidMasse moléculaire :461.94Retro-2
CAS :Retro-2 (2-{[(5-methyl-2-thienyl)methylene]amino}) is a plant toxin ricin inhibitor, it protects HeLa cells against Ricin, Stx1 and Stx2.Formule :C19H16N2OSDegré de pureté :98.15%Couleur et forme :SolidMasse moléculaire :320.41Parthenolide
CAS :Parthenolide ((-)-Parthenolide) is a natural sesquiterpene lactone that is an NF-κB and HDAC1 inhibitor with anti-inflammatory effect. Cost-effective and quality-assured.Formule :C15H20O3Degré de pureté :99.10% - 99.46%Couleur et forme :White To Pale Yellow Crystalline PowderMasse moléculaire :248.32NH125
CAS :NH125 is a selective eEF-2 kinase inhibitor with IC50 of 60 nM, >125-fold selectivity over PKC, PKA, and CaMKII, and also a potent histidine kinase inhibitor.Formule :C27H45IN2Degré de pureté :98.60%Couleur et forme :SolidMasse moléculaire :524.56Ref: TM-T6605
1mg40,00€2mg52,00€5mg88,00€10mg119,00€25mg264,00€50mg454,00€100mg655,00€1mL*10mM (DMSO)87,00€Cobaltic Protoporphyrin IX chloride
CAS :Cobaltic Protoporphyrin IX chloride (CoPP) is a potent heme oxygenase 1 (HO-1) inducer with antiviral activity that inhibits influenza A virus (IAV) infection by inducing a type I IFN response. mTOR inhibitor-8 is a potent mTOR inhibitor and autophagy inducer with antiviral and antitumor activities.Formule :C34H32ClCoN4O4Degré de pureté :≥95.0%Couleur et forme :SolidMasse moléculaire :655.03Autophagy-IN-7
CAS :Autophagy-IN-7 is an autophagy inhibitor that can be used in tumor research.Formule :C15H11N7Couleur et forme :SolidMasse moléculaire :289.295VX-702
CAS :VX-702: selective p38α MAPK inhibitor, potent anti-cytokine for rheumatoid arthritis.Formule :C19H12F4N4O2Degré de pureté :100% - 99%Couleur et forme :SolidMasse moléculaire :404.32TBHQ
CAS :TBHQ (tert-Butylhydroquinone) is an antioxidant that induces an antioxidant response through the redox-sensitive transcription factor Nrf2.Formule :C10H14O2Degré de pureté :99.17% - 99.53%Couleur et forme :White Solid PowderMasse moléculaire :166.22Ranolazine dihydrochloride
CAS :Ranolazine 2HCl, an antianginal, treats arrhythmia by inhibiting sodium current without changing blood pressure or heart rate.Formule :C24H35Cl2N3O4Degré de pureté :100% - 99.96%Couleur et forme :White Crystalline PowderMasse moléculaire :500.46BRD5631
CAS :BRD5631 is an autophagy enhancer, enhances autophagy through an mTOR-independent pathway.Formule :C30H35N3O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :501.62GDC-0349
CAS :GDC-0349 (RG-7603) is a potent and selective ATP-competitive inhibitor of mTOR, 790-fold inhibitory effect against PI3Kα and other 266 kinases. Phase 1.Formule :C24H32N6O3Degré de pureté :96.00% - 98.98%Couleur et forme :SolidMasse moléculaire :452.55Ref: TM-T6510
2mg39,00€5mg66,00€10mg107,00€25mg215,00€50mg324,00€100mg462,00€500mgÀ demander1mL*10mM (DMSO)70,00€Afatinib Dimaleate
CAS :Afatinib Dimaleate (BIBW 2992MA2) is an orally bioavailable anilino-quinazoline derivative and inhibitor of the EGFR family, with antineoplastic activity.Formule :C32H33ClFN5O11Degré de pureté :100% - 98.11%Couleur et forme :SolidMasse moléculaire :718.08Ref: TM-T1773
1g467,00€5mg40,00€10mg59,00€25mg87,00€50mg107,00€100mg140,00€200mg188,00€500mg313,00€1mL*10mM (DMSO)66,00€mTOR inhibitor-1
CAS :C-4 is a potential ATP-competitive inhibitor of mTOR. C-4 could inhibit cell growth and proliferation.Formule :C16H15BrN2O3Degré de pureté :99.43%Couleur et forme :SolidMasse moléculaire :363.21kaempferide
CAS :kaempferide (4'-Methylkaempferol) is an O-methylated flavonol present in Kaempferia kaempferi with antiviral activity.Formule :C16H12O6Degré de pureté :98.31% - 99.66%Couleur et forme :SolidMasse moléculaire :300.26SBE13 Hydrochloride
CAS :SBE13 Hydrochloride (SBE 13 HCl) is an effective and specific PLK1 inhibitor (IC50: 0.2 nM); no inhibition om Aurora A kinase, Plk2/3.Formule :C24H28Cl2N2O4Degré de pureté :97.98% - ≥95%Couleur et forme :SolidMasse moléculaire :479.4Clinofibrate
CAS :Clinofibrate lowers lipids, blocks HMGCR (IC50: 0.47 mM), and controls cholesterol/triacylglycerides.Formule :C28H36O6Degré de pureté :99.84%Couleur et forme :White Crystalline PowderMasse moléculaire :468.58XCT790
CAS :XCT790 is a potent, selective and inverse agonist of estrogen-related receptor alpha(ERRα).Formule :C23H13F9N4O3SDegré de pureté :99% - 99.74%Couleur et forme :SolidMasse moléculaire :596.42Pregnenolone
CAS :Pregnenolone (Arthenolone) is an endogenous steroid hormone synthesized from cholesterol, used in the treatment of Alzheimer's disease.Formule :C21H32O2Degré de pureté :100% - 99.5%Couleur et forme :SolidMasse moléculaire :316.48Vancomycin hydrochloride
CAS :Vancomycin hydrochloride (Vancomycin HCl) is the hydrochloride salt of vancomycin, a branched tricyclic glycosylated peptide with bactericidal activity againstFormule :C66H76Cl3N9O24Degré de pureté :97.20% - 99.19%Couleur et forme :Off White PowderMasse moléculaire :1485.71Losmapimod
CAS :Losmapimod (GSK-AHAB) (GW856553X; SB856553; GSK-AHAB) is a specific, potent, and orally active p38 MAPK inhibitor (pKi: 8.1/7.6 for p38α/β).Formule :C22H26FN3O2Degré de pureté :98.56% - 99.05%Couleur et forme :SolidMasse moléculaire :383.46Ref: TM-T2277
2mg35,00€5mg52,00€10mg78,00€25mg139,00€50mg225,00€100mg406,00€500mg920,00€1mL*10mM (DMSO)55,00€Lanatoside C
CAS :Lanatoside C, a cardiac glycoside, treats heart failure and arrhythmia; taken orally or IV.Formule :C49H76O20Degré de pureté :100% - 99.8%Couleur et forme :SolidMasse moléculaire :985.12Doramapimod
CAS :Doramapimod (BIRB 796) is a highly potent inhibitor of p38 MAPK (Kd: 0.1 nM), but weakly inhibits c-RAF, Fyn, Lck, ERK-1, SYK, IKK2, and ZAP-70.Formule :C31H37N5O3Degré de pureté :97.73% - 98.80%Couleur et forme :SolidMasse moléculaire :527.66Ref: TM-T6277
1g562,00€5mg37,00€10mg55,00€25mg79,00€50mg92,00€100mg127,00€200mg225,00€500mg379,00€1mL*10mM (DMSO)44,00€QN523
CAS :QN523 has drug-like traits, kills cancer cells in vitro, effective in vivo against pancreatic cancer, works via autophagy.Formule :C14H10N4ODegré de pureté :97.26%Couleur et forme :SolidMasse moléculaire :250.26Ref: TM-T64374
1mg35,00€5mg74,00€10mg105,00€25mg207,00€50mg325,00€100mg469,00€200mg650,00€1mL*10mM (DMSO)71,00€Rosiglitazone
CAS :Rosiglitazone (BRL49653) is a PPARγ agonist, TRPC5 activator, and TRPM3 inhibitor with oral activity.Formule :C18H19N3O3SDegré de pureté :98.61% - 99.87%Couleur et forme :White To Off-White Crystalline PowderMasse moléculaire :357.43Valproic Acid
CAS :Valproic Acid (2-Propylpentanoic Acid) is a branched chain fatty acid which potentially enhances central GABAergic neurotransmission and inhibits Na+ channels.Formule :C8H16O2Degré de pureté :98.91% - 99.49%Couleur et forme :Colourless To Pale Yellow Liquid ViscousMasse moléculaire :144.21Tigecycline
CAS :Tigecycline (GAR-936), a broad-spectrum glycylcycline, disrupts protein synthesis by binding the 30S ribosomal subunit.Formule :C29H39N5O8Degré de pureté :100% - 99.94%Couleur et forme :PowderMasse moléculaire :585.65Ref: TM-T1569
5mg38,00€10mg57,00€25mg79,00€50mg105,00€100mg168,00€200mg248,00€500mg418,00€1mL*10mM (DMSO)59,00€Demethoxycurcumin
CAS :Demethoxycurcumin: antioxidant, anti-inflammatory, anti-proliferative, anti-acanthamoebic, enhances chemo for resistant cancers, inhibits cancer pathways.Formule :C20H18O5Degré de pureté :94.54% - 98.1%Couleur et forme :SolidMasse moléculaire :338.35QX77
CAS :QX77 is a chaperone-mediated autophagy (CMA) activator.Formule :C16H13ClN2O2Degré de pureté :98.21%Couleur et forme :SolidMasse moléculaire :300.74Afatinib
CAS :Afatinib (BIBW 2992) is an irreversible and orally EGFR family inhibitor that inhibits EGFR and HER2. Afatinib has antitumor activity. Cost effective and quality assured.Formule :C24H25ClFN5O3Degré de pureté :97.56% - 99.9%Couleur et forme :Off-White SolidMasse moléculaire :485.94Ref: TM-T21312
5mg35,00€10mg51,00€25mg86,00€50mg115,00€100mg144,00€200mg177,00€500mg300,00€1mL*10mM (DMSO)52,00€p62-ZZ Ligand-Linker Conjugate 1
CAS :p62-ZZ Ligand-Linker Conjugate 1 is a conjugate of the p62-ZZ domain ligand and linker. This compound is utilized in the synthesis of AUTOTACVinclozolinM2-2204.Formule :C31H42N2O6Couleur et forme :SolidMasse moléculaire :538.68Ciclopirox
CAS :Ciclopirox is an antifungal that chelates Fe3+ and Al3+, inhibiting enzymes and has antibacterial and anti-inflammatory effects.Formule :C12H17NO2Degré de pureté :97.72% - 99.41%Couleur et forme :SolidMasse moléculaire :207.27Vps34-PIK-III
CAS :Vps34-PIK-III (VPS34-IN2), a selective inhibitor of VPS34 enzymatic activity, inhibits autophagy and results in the stabilization of autophagy substrates.Formule :C17H17N7Degré de pureté :98.39% - 98.43%Couleur et forme :SolidMasse moléculaire :319.36Ref: TM-T6945
1mg51,00€2mg71,00€5mg116,00€10mg202,00€25mg454,00€50mg663,00€100mg944,00€500mg1.890,00€1mL*10mM (DMSO)116,00€Nitrendipine
CAS :Nitrendipine is a vasodilating calcium channel blocker and antihypertensive that preserves kidney function and promotes sodium excretion.Formule :C18H20N2O6Degré de pureté :99.54% - 99.55%Couleur et forme :SolidMasse moléculaire :360.36Ref: TM-T0119
1g437,00€10mg38,00€25mg55,00€50mg71,00€100mg119,00€200mg175,00€500mg283,00€1mL*10mM (DMSO)55,00€HA15
CAS :HA15 targets BiP/GRP78/HSPA5, showing anti-cancer effects on all tested melanoma cells, resistant or patient-derived.Formule :C23H22N4O3S2Degré de pureté :99.77% - 99.86%Couleur et forme :SolidMasse moléculaire :466.58Ref: TM-T6855
1mg40,00€2mg51,00€5mg84,00€10mg96,00€25mg187,00€50mg329,00€100mg567,00€1mL*10mM (DMSO)84,00€Veliparib dihydrochloride
CAS :Veliparib dihydrochloride (ABT-888 dihydrochloride) is a potent inhibitor of PARP1 and PARP2 with Ki of 5.2 nM and 2.9 nM in cell-free assays, respectively.Formule :C13H18Cl2N4ODegré de pureté :97.09% - 98%Couleur et forme :SolidMasse moléculaire :317.21Danshensu sodium salt
CAS :Danshensu sodium salt (Sodium Danshensu) is sodium salt of danshensu from the widely used Chinese herb Danshen.Formule :C9H9NaO5Degré de pureté :97.04% - 99.52%Couleur et forme :SolidMasse moléculaire :220.16LRRK2 inhibitor 1
CAS :LRRK2 inhibitor 1 is a selective and potent LRRK2 inhibitor with an IC50 of 13 nM.LRRK2 inhibitor 1 inhibits DCLK1 kinase with an IC50 value of 2.61 nM.Formule :C20H23N5O4Degré de pureté :99.73%Couleur et forme :SolidMasse moléculaire :397.43Ref: TM-T11878
1mg74,00€2mg97,00€5mg160,00€10mg264,00€25mg557,00€50mg944,00€100mg1.491,00€1mL*10mM (DMSO)170,00€Chloroquine phosphate
CAS :Chloroquine phosphate (Aralen phosphate) is an aminoquinoline antimalarial and also is used as an autophagy inhibitor. Chloroquine also is an inhibitor of TLRs.Formule :C18H26CLN3·2(H3PO4)Degré de pureté :99.64% - ≥95%Couleur et forme :White To Slightly Yellow Crystalline Powder White SolidMasse moléculaire :515.87SRT 1720
CAS :SRT 1720 is a selective activator of human SIRT1 (EC1.5: 0.16 μM) and is >230-fold less potent for SIRT2 and SIRT3.Formule :C25H23N7OSDegré de pureté :98.84%Couleur et forme :SolidMasse moléculaire :469.56Piperlongumine
CAS :Piperlongumine (Piplartine) is a natural alkaloid from Piper longum L.Formule :C17H19NO5Degré de pureté :97.03% - 99.89%Couleur et forme :SolidMasse moléculaire :317.34Andrographolide
CAS :Andrographolide (Andrographis)(Andrographis), an irreversible antagonist of NF-κB, has anti-inflammatory and anti-platelet aggregation activities and potentialFormule :C20H30O5Degré de pureté :100% - 99.97%Couleur et forme :PowderMasse moléculaire :350.45L-779450
CAS :L-779450, an effective, ATP-competitive Raf kinase inhibitor (IC50: 10 nM) , displays >7, >30 and >70-fold selectivity over p38α, GSK3β and Lck respectively.Formule :C20H14ClN3ODegré de pureté :≥95%Couleur et forme :SolidMasse moléculaire :347.86-Thioguanine
CAS :6-Thioguanine (2-Amino-6-purinethiol) is an antineoplastic compound which also has antimetabolite action. The drug is used in the therapy of acute leukemia.Formule :C5H5N5SDegré de pureté :100% - 98.75%Couleur et forme :Odorless Or Almost Odorless Pale Yellow Crystalline PowderMasse moléculaire :167.19Quisinostat dihydrochloride
CAS :Quisinostat dihydrochloride (JNJ26854165(Quisinostat) 2HCl) 是一种有口服活性,高效的 pan-HDAC 抑制剂,具有广泛的抗肿瘤活性。它对 HDAC1、HDAC2、HDAC4、HDAC10和HDAC11 的IC50值分别为 0.11 nM、0.33 nM、0.64 nM、0.46 nM 和 0.37 nM。Formule :C21H28Cl2N6O2Degré de pureté :97.13%Couleur et forme :SolidMasse moléculaire :467.39Zebularine
CAS :Zebularine (4-Deoxyuridine) is a DNA methylation inhibitor.Formule :C9H12N2O5Degré de pureté :100% - 99.84%Couleur et forme :SolidMasse moléculaire :228.2Everolimus
CAS :Everolimus (SDZ-RAD) is a potent mTOR inhibitor that binds to FKBP-12. It is used alone or in combination with calcineurin inhibitors.Formule :C53H83NO14Degré de pureté :97.76% - 99.52%Couleur et forme :Off-White To Light Yellow PowdMasse moléculaire :958.22Ref: TM-T1784
5mg44,00€10mg55,00€25mg82,00€50mg96,00€100mg120,00€200mg177,00€500mg298,00€1mL*10mM (DMSO)55,00€Sodium salicylate
CAS :Sodium salicylate (2-Hydroxybenzoic acid sodium salt), a metabolite of acetylsalicylic acid, can inhibit NF-kB and reduce oxidative stress.Formule :C7H5NaO3Degré de pureté :99.36% - 99.77%Couleur et forme :White Solid AmorphousMasse moléculaire :160.11Cilofexor
CAS :Cilofexor inhibits binding of a synthetic peptide, Cilofexor is a farnesoid X receptor (FXR) agonist.Formule :C28H22Cl3N3O5Degré de pureté :99.32% - ≥95%Couleur et forme :SolidMasse moléculaire :586.85Ref: TM-T7436
1mg50,00€2mg73,00€5mg124,00€10mg188,00€25mg380,00€50mg567,00€100mg807,00€500mg1.644,00€1mL*10mM (DMSO)158,00€Rosolutamide
CAS :Rosolutamide (ALZ-003) is a curcumin analog, an Nrf1 and Nrf2 activator.Formule :C28H32O6Degré de pureté :96.54% - 99.36%Couleur et forme :SolidMasse moléculaire :464.55Pantoprazole Sodium Hydrate
CAS :Pantoprazole Sodium Hydrate (BY1023 (sodium hydrate)) is a proton pump inhibitor drug, used for short-term treatment of erosion and ulceration of the esophagusFormule :C16H14F2N3NaO4SH2ODegré de pureté :98.32%Couleur et forme :SolidMasse moléculaire :432.37Di-N-desethyl amiodarone hydrochloride
CAS :Di-N-desethyl Amiodarone hydrochloride, a metabolite of Amiodarone, functions as a potent inhibitor of the respiratory chain [1].Formule :C21H22ClI2NO3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :625.67Eupatilin
CAS :Eupatilin (NSC-122413), a flavone derived from Artemisia princepsPampanini, is a PPARα agonist, with pharmacological activity.Formule :C18H16O7Degré de pureté :98.42% - 99%Couleur et forme :SolidMasse moléculaire :344.32UVI 3003
CAS :UVI 3003 blocks retinoid X receptor (RXRα) in Xenopus/human Cos7 cells; IC50: 0.22/0.24 μM.Formule :C28H36O4Degré de pureté :99.82%Couleur et forme :SolidMasse moléculaire :436.58Ref: TM-T17209
1mg35,00€2mg52,00€5mg74,00€10mg119,00€25mg243,00€50mg406,00€100mg607,00€1mL*10mM (DMSO)86,00€NDBM
NDBM, a tumor-specific probe that targets Pim-1 kinase, exhibits heightened fluorescence upon binding and induces cytotoxicity, facilitating both cell screeningFormule :C33H35BrN4O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :679.56Magnolol
CAS :Magnolol (5,5'-Diallyl-2,2'-biphenyldiol) is a dual agonist of RXRα( EC50=10.4 μM) and PPARγ(EC50=17.7 μM). It blocks TNF-α-induced NF-KB activation.Formule :C18H18O2Degré de pureté :99.49%Couleur et forme :A Bioactive Compound Found In The Bark Of The Houpu MagnoliaMasse moléculaire :266.33CUR5g
CAS :CUR5g is an autophagy inhibitor that inhibits migration and colony formation in A549 cells.Formule :C22H20N2O2Degré de pureté :98.92%Couleur et forme :SolidMasse moléculaire :344.41Ref: TM-T73550
1mg92,00€5mg216,00€10mg344,00€25mg692,00€50mg1.103,00€100mg1.644,00€1mL*10mM (DMSO)240,00€ATG7-IN-1
CAS :ATG7-IN-1 is a selective ATG7 inhibitor with an IC50 of 62 nM.Formule :C17H19FN6O5S2Degré de pureté :100% - 100%Couleur et forme :SolidMasse moléculaire :470.5BAR502
CAS :BAR502 is a dual GPBAR1 and FXR agonist (IC50s: 0.4 μM and 2 μM).Formule :C25H44O3Degré de pureté :99.95%Couleur et forme :SolidMasse moléculaire :392.62Resatorvid
CAS :Resatorvid (TAK-242) inhibits TLR4, with IC50s for IL-6, TNF-R, NO at 1.3, 1.9, 1.8 nM respectively.Formule :C15H17ClFNO4SDegré de pureté :100% - 99.9%Couleur et forme :SolidMasse moléculaire :361.82Ref: TM-TQ0181
1mg49,00€2mg70,00€5mg96,00€10mg164,00€25mg306,00€50mg502,00€100mg805,00€1mL*10mM (DMSO)116,00€Polydatin
CAS :Polydatin, a resveratrol glycoside from Polygonum cuspidatum, inhibits platelet aggregation, alters lipid ratios, and modulates cell functions.Formule :C20H22O8Degré de pureté :97.2% - 98.83%Couleur et forme :White Fine PowderMasse moléculaire :390.38LC3-mHTT-IN-AN2
CAS :LC3-mHTT-IN-AN2 (5,7-Dihydroxy-4-phenylcoumarin) is found in the plant Passiflora serratodigitata with the antibacterial activity.Formule :C15H10O4Degré de pureté :≥98%Couleur et forme :SolidMasse moléculaire :254.24Clemastine fumarate
CAS :Clemastine fumarate (Meclastine (fumarate)) is a synthetic ethanolamine with anticholinergic, sedative, and histamine H1 antagonistic properties.Formule :C25H30ClNO5Degré de pureté :99.52% - 99.8%Couleur et forme :Colorless To Faintly Yellow Crystalline Powder Appearance White Or Almost White Crystalline PowderMasse moléculaire :459.97Rabusertib
CAS :Rabusertib (IC-83) is a chk1 inhibitor in trials for various cancers, including pancreatic and non-small cell lung cancer.Formule :C18H22BrN5O3Degré de pureté :98.86% - 99.63%Couleur et forme :SolidMasse moléculaire :436.3Dehydrocorydaline chloride
CAS :Dehydrocorydaline chloride (13-Methylpalmatine chloride) is an alkaloid with anti-inflammatory and anti-cancer activity. Can improve the activation of p38 MAPK.Formule :C22H24ClNO4Degré de pureté :99.53%Couleur et forme :SolidMasse moléculaire :401.88Ref: TM-T10990
1mg58,00€5mg111,00€10mg160,00€25mg264,00€50mg396,00€100mg563,00€1mL*10mM (DMSO)124,00€ATG16L1 stabilizer-1
ATG16L1 stabilizer-1 (compound A3B) is an FKBP12-independent stabilizer of ATG16L1 that enhances cellular autophagy (Autophagy). Regardless of the presence of FKBP12, it has an inhibitory EC50 value of 12.1 μM for ATG16L1. When used alone, ATG16L1 stabilizer-1 can induce GFP-LC3 puncta formation, with an EC50 value of 12.0 μM.Formule :C45H62N14O5SCouleur et forme :SolidMasse moléculaire :911.13Bafilomycin A1
CAS :Bafilomycin A1 belongs to the macrolide class of antibiotics and is a V-ATPase (IC50=0.44 nM) that is specific and reversible.Formule :C35H58O9Degré de pureté :95.87% - 99.36%Couleur et forme :SolidMasse moléculaire :622.83Temsirolimus
CAS :Temsirolimus (CCI-779) is a specific mTOR inhibitor ( IC50: 1.76 μM), used in the treatment of advanced renal cell cancer.Formule :C56H87NO16Degré de pureté :100% - 99.64%Couleur et forme :White Crystalline PowderMasse moléculaire :1030.29Quisinostat
CAS :Quisinostat (JNJ-26481585), a second-gen HDAC inhibitor, is most potent for HDAC1 (IC50 0.11 nM) and selectively affects HDACs 2, 4, 10, and 11.Formule :C21H26N6O2Degré de pureté :96.01% - ≥98%Couleur et forme :SolidMasse moléculaire :394.47Ref: TM-T6055
1mg59,00€2mg86,00€5mg124,00€10mg213,00€25mg331,00€50mg427,00€100mg607,00€1mL*10mM (DMSO)139,00€Oroxylin A
CAS :Oroxylin A fights tumors, aids RAS therapy, promotes CaCo-2 cell apoptosis, blocks MCF-7 cell invasion and enhances leukemia treatment.Formule :C16H12O5Degré de pureté :98.72% - 99.55%Couleur et forme :SolidMasse moléculaire :284.26Aceglutamide
CAS :Aceglutamide (N2-Acetylglutamine) is an acetyl derivative of the amino acid L-glutamine, used to improve memory.Formule :C7H12N2O4Degré de pureté :99.56% - 99.77%Couleur et forme :SolidMasse moléculaire :188.18Spironolactone
CAS :Spironolactone (SC9420) is an Aldosterone Antagonist. The mechanism of action of spironolactone is as an Aldosterone Antagonist.Formule :C24H32O4SDegré de pureté :99.87%Couleur et forme :White PowderMasse moléculaire :416.57Nortriptyline hydrochloride
CAS :Nortriptyline HCl, a metabolite of amitriptyline, treats major and atypical depression, dysthymia.Formule :C19H22ClNDegré de pureté :100% - ≥95%Couleur et forme :SolidMasse moléculaire :299.84MTP
CAS :MTP, a PKM2 inhibitor, promotes apoptosis in cancer cells via caspase-3 activation while also inducing autophagy and enhancing ROS generation.Formule :C29H23F3N4O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :516.51GC7 Sulfate
CAS :GC7 Sulfate blocks DHS, the sole enzyme activating eIF5A2, thus preventing eIF5A2 activation.Formule :C8H22N4O4SDegré de pureté :100% - 99.85%Couleur et forme :SolidMasse moléculaire :270.35Brazilin
CAS :1.Formule :C16H14O5Degré de pureté :98% - 99.83%Couleur et forme :SolidMasse moléculaire :286.28Ref: TM-T6S1784
1mg37,00€5mg74,00€10mg97,00€25mg157,00€50mg224,00€100mg335,00€200mg497,00€1mL*10mM (DMSO)81,00€LYS01
CAS :LYS01 free base is a new lysosomal autophagy inhibitor.Formule :C23H23Cl2N5Degré de pureté :98.28%Couleur et forme :SolidMasse moléculaire :440.37Lumefantrine
CAS :Lumefantrine, an antimalarial, treats malaria with artemether, effective against Plasmodium spp. including in chloroquine-resistant areas.Formule :C30H32Cl3NODegré de pureté :98.36%Couleur et forme :Yellow SolidMasse moléculaire :528.94Aliskiren hemifumarate
CAS :Aliskiren hemifumarate (CGP60536B) is an orally active nonpeptide renin inhibitor with antihypertensive activity.Formule :C30H53N3O6C4H4O4Degré de pureté :96.18% - 99.21%Couleur et forme :SolidMasse moléculaire :1219.6Zoledronic Acid
CAS :Zoledronic Acid (ZOL 446) 是一种含氮二磷酸盐,能抑制破骨细胞的分化和凋亡,具有高效的抗骨质再吸收活性,也有抗癌作用。Formule :C5H10N2O7P2Degré de pureté :98% - 99.93%Couleur et forme :White Crystalline PowderMasse moléculaire :272.09GSK343
CAS :GSK343, a specific and effective EZH2 inhibitor (IC50=4 nM), exhibits 60 fold specificity activity against EZH1, and >1000 fold specificity activity againstFormule :C31H39N7O2Degré de pureté :98% - 99.9%Couleur et forme :SolidMasse moléculaire :541.69Theophylline
CAS :Theophylline (1,3-Dimethylxanthine) is a methyl xanthine derivative from tea with diuretic, smooth muscle relaxant, bronchial dilation, cardiac and centralFormule :C7H8N4O2Degré de pureté :99.47% - 99.97%Couleur et forme :White Solid PowderMasse moléculaire :180.16Chenodeoxycholic acid
CAS :Chenodeoxycholic acid (CDCA), a bile acid, usually conjugated with either glycine or taurine, acts as a detergent to solubilize fats for intestinal absorption.Formule :C24H40O4Degré de pureté :99.70% - 99.72%Couleur et forme :White - Almost White Solid PowderMasse moléculaire :392.57Monacolin J
CAS :Monacolin J (Antibiotic MB 530A) is a cholesterol biosynthesis inhibitor.Formule :C19H28O4Degré de pureté :98.06%Couleur et forme :SolidMasse moléculaire :320.42Ref: TM-T12092
1mg79,00€5mg160,00€10mg235,00€25mg398,00€50mg567,00€100mg820,00€1mL*10mM (DMSO)170,00€Purmorphamine
CAS :Purmorphamine (Shh Signaling Antagonist VI), which directly binds and activates Smoothened, blocks BODIPY-cyclopamine binding to Smo.Formule :C31H32N6O2Degré de pureté :97.19% - 99.48%Couleur et forme :Light Tan SolidMasse moléculaire :520.62Glyphosate
CAS :Glyphosate (Atila) is an herbicide. It also is a possible carcinogen to humans.Formule :C3H8NO5PDegré de pureté :99.42% - 99.79%Couleur et forme :White Crystals (Darkens) Ph (1% Solution In Water) 2 5 (Ntp 1992)Masse moléculaire :169.07Itraconazole
CAS :Itraconazole (R51211) is a triazole antifungal agent that inhibits cytochrome P-450-dependent enzymes required for ERGOSTEROL synthesis.Formule :C35H38Cl2N8O4Degré de pureté :98% - 99.90%Couleur et forme :Off-White Crystalline SolidMasse moléculaire :705.63CZC-25146 hydrochloride
CAS :CZC-25146 is a selective LRRK2 inhibitor with IC50 of 4.76 nM/6.87 nM for wild type LRRK2 and G2019S LRRK2, respectively.Formule :C22H26ClFN6O4SDegré de pureté :98.76%Couleur et forme :SolidMasse moléculaire :525CX546
CAS :CX546 is an AMPA receptor modulator. CX546 enhances cognitive function in rats. It has also been proposed as a treatment for schizophrenia.Formule :C14H17NO3Degré de pureté :99.75%Couleur et forme :SolidMasse moléculaire :247.29Betulinic acid
CAS :Betulinic acid, a lupane-type triterpene from white birch bark, has antiretroviral, antimalarial, anti-inflammatory, and anticancer properties.Formule :C30H48O3Degré de pureté :99.12% - 99.7%Couleur et forme :White Crystalline PowderMasse moléculaire :456.7
