Autophagie
Les inhibiteurs de l'autophagie ciblent le processus cellulaire de l'autophagie, qui implique la dégradation et le recyclage des composants cellulaires via les lysosomes. L'autophagie est un mécanisme crucial pour maintenir l'homéostasie cellulaire, mais sa dérégulation est impliquée dans diverses maladies, y compris le cancer, les maladies neurodégénératives et les infections. Les inhibiteurs de l'autophagie peuvent bloquer ce processus, ce qui en fait des outils précieux pour étudier le rôle de l'autophagie dans les maladies et développer des stratégies thérapeutiques. Chez CymitQuimica, nous proposons des inhibiteurs de l'autophagie pour soutenir vos recherches en biologie cellulaire, oncologie et maladies neurodégénératives.
Produits appartenant à la catégorie "Autophagie"
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Dinoprost
CAS :Dinoprost (Prostaglandin F2a) is a naturally occurring prostaglandin. It is used in medicine to induce labor and as an abortifacient.Formule :C20H34O5Degré de pureté :≥98%Couleur et forme :White To Off-White Crystalline SolidMasse moléculaire :354.48Ref: TM-T15133
5mg51,00€10mg79,00€25mg144,00€50mg216,00€100mg344,00€200mg512,00€1mL*10mM (DMSO)57,00€Pantoprazole sodium
CAS :Pantoprazole sodium is a proton pump inhibitor that irreversibly blocks gastric acid secretion by bonding with H+/K+-ATPase.Formule :C16H14F2N3NaO4SDegré de pureté :96.92% - 99.81%Couleur et forme :White To Off-White SolidMasse moléculaire :405.35Elexacaftor
CAS :Elexacaftor (VX-445) is a cystic fibrosis transmembrane conductance regulator (CFTR) corrector.Cost-effective and quality-assured.Formule :C26H34F3N7O4SDegré de pureté :98.87% - 99.87%Couleur et forme :SolidMasse moléculaire :597.65Ref: TM-T14935
1mg87,00€2mg137,00€5mg243,00€10mg393,00€25mg772,00€50mg1.074,00€100mg1.444,00€1mL*10mM (DMSO)320,00€TFEB activator 1
CAS :TFEB activator 1 (Curcumin analog compound C1) is an activator of transcription factor EB (TFEB) with promise for the prevention or treatment of Alzheimer'sFormule :C19H18O3Degré de pureté :98.87%Couleur et forme :SolidMasse moléculaire :294.34AZD7624
CAS :AZD7624 is an p38 inhibitor. It has potent anti-inflammatory activity.Formule :C27H30FN5O3Degré de pureté :99.37%Couleur et forme :SolidMasse moléculaire :491.56Ref: TM-T14381
1mg73,00€5mg160,00€10mg250,00€25mg507,00€50mg737,00€100mg1.026,00€1mL*10mM (DMSO)170,00€SR10067
CAS :SR10067 is a potent, selective and brain penetrant agonist of Rev-Erbβ(IC50 = 160 nM) and Rev-Erbα(IC50 = 170 nM) with anxiolytic activity.Formule :C31H31NO3Degré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :465.58Ref: TM-T12998
1mg58,00€5mg134,00€10mg207,00€25mg353,00€50mg510,00€100mg658,00€200mg905,00€1mL*10mM (DMSO)144,00€Oxidopamine hydrobromide
CAS :Oxidopamine hydrobromide (6-OHDA hydrobromide) is a neurotransmitter dopamine antagonist.Formule :C8H12BrNO3Degré de pureté :98.1% - 99.88%Couleur et forme :Beige To Brown Fine Crystalline PowderMasse moléculaire :250.09Naringin
CAS :Naringin: flavanone glycoside with blood lipid-reducing, antioxidant, anticancer properties, inhibits cytochrome P450.Formule :C27H32O14Degré de pureté :99.23%Couleur et forme :Beige Creamish Powder Solid Solid Particulate/PowderMasse moléculaire :580.53FMK 9a
CAS :FMK 9a is an irreversible inhibitor of ATG4B with IC50 values of 80 and 73 nM in the TR-FRET and cellular-based LRA assays.Formule :C23H21FN2O3Degré de pureté :98.97%Couleur et forme :SolidMasse moléculaire :392.42Ref: TM-T15303
1mg139,00€5mg329,00€10mg494,00€25mg800,00€50mg1.103,00€100mg1.491,00€500mg2.973,00€1mL*10mM (DMSO)284,00€GPP78
CAS :GPP78: Strong Nampt inhibitor, IC50 3.0 nM, depletes NAD. Kills SH-SY5Y cells, IC50 3.8 nM via autophagy. Anti-cancer and anti-inflammatory.Formule :C27H29N5ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :439.55MRT67307
CAS :Through its effects on ULK1 and ULK2, MRT67307 blocks autophagy.Formule :C26H36N6O2Degré de pureté :99.25% - 99.79%Couleur et forme :SolidMasse moléculaire :464.6Nidufexor
CAS :Nidufexor is an agonist for the farnesoid X receptor (FXR).Formule :C27H22ClN3O4Degré de pureté :98.67%Couleur et forme :SolidMasse moléculaire :487.93Daphnetin
CAS :Daphnetin (7,8-Dihydroxycoumarin), a natural coumarin derivative, is a protein kinase inhibitor with inhibitory for EGFR (IC50: 7.67 μM), PKA (IC50: 9.33 μM),Formule :C9H6O4Degré de pureté :97.47% - 99.8%Couleur et forme :SolidMasse moléculaire :178.14Paroxetine hydrochloride
CAS :Paroxetine hydrochloride (Paroxetine HCl) is a serotonin uptake inhibitor that is effective in the treatment of depression.Formule :C19H21ClFNO3Degré de pureté :98% - 99.99%Couleur et forme :White Crystalline PowderMasse moléculaire :365.826Ruxolitinib phosphate
CAS :Ruxolitinib phosphate (INCB18424 phosphate) is a JAK1/2 inhibitor with IC50 of 3.3 nM/2.8 nM. Cost-effective and quality-assured.Formule :C17H21N6O4PDegré de pureté :100% - 99.91%Couleur et forme :SolidMasse moléculaire :404.36Ref: TM-T3043
1g615,00€5mg52,00€10mg65,00€25mg82,00€50mg97,00€100mg145,00€200mg227,00€500mg418,00€1mL*10mM (DMSO)59,00€Doxorubicin hydrochloride
CAS :Doxorubicin hydrochloride (Adriamycin) belongs to the anthracycline class of antibiotics and is an inhibitor of human DNA topoisomerase I/II (IC50=0.8/2.67 μM).Formule :C27H29NO11·HClDegré de pureté :98% - 99.36%Couleur et forme :Orange-Red At Neutral Phs And Violet Blue Over Ph 9 (Ntp 1992)Masse moléculaire :579.99Calmidazolium chloride
CAS :Calmidazolium chloride blocks calmodulin, hinders phosphodiesterase (IC50=0.15µM), Ca2+-ATPase (IC50=0.35µM), and can induce cancer cell apoptosis.Formule :C31H23Cl7N2ODegré de pureté :98.06%Couleur et forme :SolidMasse moléculaire :687.7Ref: TM-T10667
5mg63,00€10mg87,00€25mg145,00€50mg215,00€100mg320,00€200mg467,00€1mL*10mM (DMSO)95,00€PF-4708671
CAS :PF-4708671 is a cell-permeable inhibitor of p70 ribosomal S6 kinase (S6K1 isoform) .In cell-free assays, PF-4708671 is potent for S6K1(Ki50=20 nM, IC50=160 nM).Formule :C19H21F3N6Degré de pureté :99.48% - 99.67%Couleur et forme :SolidMasse moléculaire :390.41Procainamide hydrochloride
CAS :Procainamide Hydrochloride (Procapan) is the hydrochloride salt form of procainamide, an amide derivative exhibiting class 1A antiarrhythmic property and analogFormule :C13H21N3O·HClDegré de pureté :99.83% - 99.97%Couleur et forme :White To Slightly Yellow PowderMasse moléculaire :271.79Pinocembrin
CAS :Pinocembrin (5,7-Dihydroxyflavanone) is a flavanone, a type of flavonoid. It is an antioxidant found in damiana, honey, fingerroot, and propolis.Formule :C15H12O4Degré de pureté :100% - 99.61%Couleur et forme :SolidMasse moléculaire :256.25Actein
CAS :Actein stimulates bone formation, counters osteoporosis and oxidative damage, and may treat lipid disorders and cancer, inhibiting breast cancer cell growth.Formule :C37H56O11Degré de pureté :≥98%Couleur et forme :Brown PowderMasse moléculaire :676.83Rutin hydrate
CAS :Rutin hydrate (Sophorin), a kind of glycoside, widely exists in many plants including citrus fruit.Formule :C27H32O17Degré de pureté :97.23%Couleur et forme :SolidMasse moléculaire :628.53Simvastatin
CAS :Simvastatin (MK 733) is an HMG-CoA reductase inhibitor (Ki=0.2 nM) with oral activity.Formule :C25H38O5Degré de pureté :98.54% - 99.13%Couleur et forme :SolidMasse moléculaire :418.57Ref: TM-T0687
10mg43,00€25mg58,00€50mg69,00€100mg106,00€200mg140,00€500mg270,00€1mL*10mM (DMSO)47,00€GW 501516
CAS :GW 501516 (Endurobol) is a effective and highly specifc PPARβ/δ agonist (EC50: 1 nM), with 1000-fold selectivity over hPPARα/γ.Formule :C21H18F3NO3S2Degré de pureté :98.91% - 99.64%Couleur et forme :White SolidMasse moléculaire :453.5Atorvastatin
CAS :Orally active atorvastatin inhibits HMG-CoA reductase, lowers lipids, hinders SV-SMC cell growth, and can up thrombotic risk with clopidogrel.Formule :C33H35FN2O5Degré de pureté :99.37% - 99.69%Couleur et forme :SolidMasse moléculaire :558.64Biochanin A
CAS :Biochanin A: an isoflavone from red clover with anticancer properties and inhibits FAAH.Formule :C16H12O5Degré de pureté :97.1% - 98.97%Couleur et forme :SolidMasse moléculaire :284.26BAY 11-7082
CAS :BAY 11-7082 (BAY 11-7821) is an NF-κB inhibitor that inhibits TNFα-induced IκBα phosphorylation (IC50=10 μM).Formule :C10H9NO2SDegré de pureté :97.91% - 99.92%Couleur et forme :SolidMasse moléculaire :207.25Ref: TM-T1902
5mg50,00€10mg57,00€25mg96,00€50mg170,00€100mg265,00€200mg399,00€500mg662,00€1mL*10mM (DMSO)52,00€CCG-1423
CAS :CCG-1423, a selective RhoA pathway inhibitor, suppresses SRF-mediated transcription.Formule :C18H13ClF6N2O3Degré de pureté :99.80%Couleur et forme :SolidMasse moléculaire :454.75CXM102
CXM102 is an activator of autophagy. This compound induces autophagy in aged BMSCs, rejuvenating them and promoting their preferential differentiation into osteoblasts. CXM102 enhances the nuclear translocation of transcription factor EB (TFEB) and the formation of osteoblasts. In middle-aged male mice, it stimulates bone anabolic metabolism, reduces marrow adipocytes, delays bone loss, lowers serum inflammation levels, reduces organ fibrosis, and extends lifespan.Formule :C28H27NO3Couleur et forme :SolidMasse moléculaire :425.52Crizotinib
CAS :Crizotinib (PF-02341066) is an ATP-competitive small-molecule tyrosine kinases inhibitor of c-MET (IC50: 8 nM) and ALK (IC50: 20 nM) receptor.Formule :C21H22Cl2FN5ODegré de pureté :99% - 99.87%Couleur et forme :SolidMasse moléculaire :450.34GW 4064
CAS :GW 4064 is an effective farnesoid X receptor (FXR) agonist (EC50 =65 nM).Formule :C28H22Cl3NO4Degré de pureté :97.47% - 99.94%Couleur et forme :SolidMasse moléculaire :542.84Ref: TM-T2233
5mg50,00€10mg84,00€25mg139,00€50mg235,00€100mg424,00€200mg640,00€500mg1.008,00€1mL*10mM (DMSO)63,00€Ralimetinib dimesylate
CAS :Ralimetinib dimesylate (LY2228820 dimesylate) is a orally available, p38 MAPK inhibitor with potential anti-inflammatory and antineoplastic activities.Formule :C24H29FN6·2CH4O3SDegré de pureté :98% - 99.38%Couleur et forme :SolidMasse moléculaire :612.74Cytarabine
CAS :Cytarabine (Ara-C) is a nucleoside analog, an inhibitor of DNA synthesis (IC50=16 nM).Formule :C9H13N3O5Degré de pureté :99.83% - 99.93%Couleur et forme :Fine Off-White Crystalline PowderMasse moléculaire :243.22Pravastatin sodium
CAS :Pravastatin sodium (CS-514 (sodium)), an HMG-CoA reductase inhibitor, inhibits sterol synthesis with IC50 of 5.6 μM.Formule :C23H35NaO7Degré de pureté :97.14%Couleur et forme :White Crystalline PowderMasse moléculaire :446.52Adenosine
CAS :Adenosine (D-Adenosine) is a ribonucleoside. Adenosine has vasodilatory, antiarrhythmic and analgesic effects. Cost-effective and quality-assured.Formule :C10H13N5O4Degré de pureté :98.76% - 99.86%Couleur et forme :Needles (From Water +3/2) Physical Description White To Off-White Crystalline Powder (Ntp 1992)Masse moléculaire :267.24Glucosamine sulfate
CAS :Glucosamine sulfate (D-Glucosaminesulfate) was extracted from synthetic product;Store the product in sealed, cool and dry condition.Formule :C6H13NO5·H2SO4Degré de pureté :99.64%Couleur et forme :White CrystalMasse moléculaire :277.25ML327
CAS :ML327 is a MYC blocker. ML327 can also de-repress E-cadherin transcription and reverse Epithelial-to-Mesenchymal Transition (EMT).Formule :C19H18N4O4Degré de pureté :99.48%Couleur et forme :SolidMasse moléculaire :366.37Sorafenib tosylate
CAS :Sorafenib tosylate (Bay 43-9006) is a potent multikinase inhibitor (IC50s: 6/20/22 nM for Raf-1/VEGFR-3/B-Raf).Formule :C21H16ClF3N4O3·C7H8O3SDegré de pureté :99.2% - 99.94%Couleur et forme :White To Off-White Crystalline PowderMasse moléculaire :637.03Nordihydroguaiaretic acid
CAS :Nordihydroguaiaretic acid (NDGA) is a natural lipoxygenase (5-LOX) inhibitor. Nordihydroguaiaretic acid has antioxidant effect. Cost-effective and quality-assured.Formule :C18H22O4Degré de pureté :97.82% - 99.91%Couleur et forme :SolidMasse moléculaire :302.36GSK2606414
CAS :GSK2606414 is a cell-permeable and orally active protein kinase R-like endoplasmic reticulum kinase(PERK)inhibitor.Cost-effective and quality-assured.Formule :C24H20F3N5ODegré de pureté :100% - 98.63%Couleur et forme :SolidMasse moléculaire :451.44Erythromycin ethylsuccinate
CAS :Erythromycin ethylsuccinate (EES) is a macrolide antibiotic, produced by Streptomyces erythreus.Formule :C43H75NO16Degré de pureté :77% - 98%Couleur et forme :White Or Slightly Yellow Crystalline Powder White To Yellowish Crystalline SolidMasse moléculaire :862.05GSK3-IN-3
CAS :GSK3-IN-3 is a mitochondrial autophagy (mitophagy) inducer and GSK-3 inhibitor (IC50: 3.01 μM) that induces parkin-dependent mitochondrial autophagy.Formule :C24H35N3O4Degré de pureté :99.37%Couleur et forme :SolidMasse moléculaire :429.55Mocetinostat
CAS :Mocetinostat (MG0103) is an orally available HDAC inhibitor with most potency for HDAC1 (IC50: 0.15 μM), 2- to 10- fold selectivity against HDAC2/3/11.Formule :C23H20N6ODegré de pureté :99% - 99.21%Couleur et forme :SolidMasse moléculaire :396.44Hemin
CAS :Hemin (Hemin chloride) is a chlorinated iron-containing porphyrin, a heme oxygenase (HO)-1 inducer.Formule :C34H32ClFeN4O4Degré de pureté :98.29% - 99.59%Couleur et forme :Dark Purple Crystalline PowderMasse moléculaire :651.94LX2343
CAS :LX2343 inhibits BACE1 (IC50: 11.43 μM) and PI3K non-competitively (IC50: 15.99 μM), and enhances autophagy for Aβ removal.Formule :C22H19ClN2O6SDegré de pureté :99.45%Couleur et forme :SolidMasse moléculaire :474.91Ref: TM-T4398
2mg37,00€5mg52,00€10mg84,00€25mg137,00€50mg229,00€100mg340,00€200mg472,00€1mL*10mM (DMSO)58,00€Perphenazine
CAS :Perphenazine (Trilafon) is a phenothiazine derivative and a dopamine antagonist with antiemetic and antipsychotic properties.Formule :C21H26ClN3OSDegré de pureté :99.3% - 99.72%Couleur et forme :SolidMasse moléculaire :403.97Naproxen sodium
CAS :Naproxen sodium (Anaprox) is a COX inhibitor for COX-1 and COX-2 with analgesic and antipyretic properties.Formule :C14H13NaO3Degré de pureté :99.68% - 99.79%Couleur et forme :White PowderMasse moléculaire :252.24Rapamycin
CAS :Rapamycin, a macrolide from Streptomyces hygroscopicus, inhibits mTOR (IC50: 0.1 nM) and promotes autophagy with immunosuppressive effects.Formule :C51H79NO13Degré de pureté :97.08% - 99.03%Couleur et forme :Yellow SolidMasse moléculaire :914.17Ref: TM-T1537
1g283,00€10mg35,00€25mg48,00€50mg52,00€100mg69,00€200mg106,00€500mg188,00€1mL*10mM (DMSO)50,00€Nimodipine
CAS :Nimodipine (BAY-e 9736), a 1, 4-dihydropyridine calcium channel blocker, acts primarily on vascular smooth muscle cells.Formule :C21H26N2O7Degré de pureté :99.64% - 99.79%Couleur et forme :SolidMasse moléculaire :418.44Thiamet G
CAS :Thiamet G is a potent, selective O-GlcNAcase inhibitor with Kiof 21 nM, while exhibiting 37, 000-fold selectivity over human lysosomal -hexosaminidase.Formule :C9H16N2O4SDegré de pureté :99.74% - 99.76%Couleur et forme :SolidMasse moléculaire :248.3Ref: TM-T6056
2mg44,00€5mg63,00€10mg93,00€25mg188,00€50mg343,00€100mg510,00€500mg1.130,00€1mL*10mM (DMSO)63,00€Fluoxetine
CAS :Fluoxetine (LY-110140), a specific serotonin inhibitor, serves as an antidepressant with fewer side-effects.Formule :C17H18F3NODegré de pureté :99.07% - 99.28%Couleur et forme :SolidMasse moléculaire :309.33Rottlerin
CAS :Rottlerin (NSC-56346), a Mallotus Philippinensis extract, inhibits PKC (3-100 μM IC50); triggers apoptosis by activating caspase 3.Formule :C30H28O8Degré de pureté :97.41% - 99.44%Couleur et forme :Orange To Brown PowderMasse moléculaire :516.54Daurisoline
CAS :Daurisoline ((R,R)-Daurisoline) is a hERG inhibitor. Daurisoline is also an autophagy blocker.Formule :C37H42N2O6Degré de pureté :98% - 99.92%Couleur et forme :Light Yellow PowderMasse moléculaire :610.74SU11274
CAS :SU11274 (Met Kinase Inhibitor)(IC50=10 nM) is a specific Met inhibitor. It shows no significant effects on PGDFRβ, EGFR or Tie2.Formule :C28H30ClN5O4SDegré de pureté :98.62% - 99.44%Couleur et forme :Orange PowderMasse moléculaire :568.09Ref: TM-T6154
1mg47,00€2mg59,00€5mg97,00€10mg150,00€25mg283,00€50mg465,00€100mg688,00€1mL*10mM (DMSO)150,00€EACC
CAS :EACC inhibits Stx17, blocking autophagosome-lysosome fusion, and is a reversible autophagy inhibitor.Formule :C13H11N3O6S2Degré de pureté :98.89%Couleur et forme :SolidMasse moléculaire :369.37AZ PFKFB3 26
CAS :AZ PFKFB3 26 is an effective and selective PFKFB3 inhibitor with an IC50 of 23 nM. The IC50s for PFKFB1 and PFKFB2 are 2.06 and 0.384 μM, respectively.Formule :C24H26N4O2Degré de pureté :98.91%Couleur et forme :SolidMasse moléculaire :402.49GSK4112
CAS :GSK4112 (SR6452) is a Rev-erbα agonist with EC50 of 0.4 μM, also is a small molecule chemical probe for the cell biology of the nuclear heme receptor Rev-erbα.Formule :C18H21ClN2O4SDegré de pureté :99.63%Couleur et forme :SolidMasse moléculaire :396.89Silmitasertib sodium salt
CAS :Silmitasertib sodium salt (CX-4945 sodium salt) is a potent and orally bioavailable, highly selective inhibitor of CK2(IC50 of 1 nM, CK2α).Formule :C19H11ClN3NaO2Degré de pureté :99.49% - 99.62%Couleur et forme :SolidMasse moléculaire :371.75Ataluren
CAS :Ataluren (PTC124) is a novel, orally administered drug that targets nonsense mutations.Formule :C15H9FN2O3Degré de pureté :99.16% - 99.84%Couleur et forme :SolidMasse moléculaire :284.24Ref: TM-T1805
5mg38,00€10mg57,00€25mg93,00€50mg124,00€100mg188,00€200mg225,00€500mg379,00€1mL*10mM (DMSO)48,00€Streptozocin
CAS :Streptozocin (NSC-85998) is an antibiotic that induces DNA methylation.Formule :C8H15N3O7Degré de pureté :100% - 99.56%Couleur et forme :Pale Yellow Crystalline PowderMasse moléculaire :265.22Bergenin
CAS :Bergenin (Bengenin) is a polyphenol, which is an effective antinarcotic agent with antioxidant action.Formule :C14H16O9Degré de pureté :99.55% - 99.60%Couleur et forme :The Loose White Needle Crystal Powder Or CrystallineMasse moléculaire :328.27NL-1
CAS :NL-1 is a mitoNEET inhibitor with antileukemic effect.Formule :C18H25NO3SDegré de pureté :98.64%Couleur et forme :SolidMasse moléculaire :335.46PH-797804
CAS :PH-797804 is a pyridinone inhibitor of p38α (IC50: 26 nM, in a cell-free assay); 4-fold more selective versus p38β and does not inhibit JNK2.Formule :C22H19BrF2N2O3Degré de pureté :97.79% - 97.90%Couleur et forme :SolidMasse moléculaire :477.3Ref: TM-T1974
1mg46,00€5mg94,00€10mg144,00€25mg255,00€50mg406,00€100mg628,00€500mg1.320,00€1mL*10mM (DMSO)97,00€Purvalanol A
CAS :Purvalanol A (NG-60) is an effective and cell-permeable CDK inhibitor with IC50 of 70/4/35/850 nM for cdk2-cyclin A/B/E, and cdk4-cyclin D1, respectively.Formule :C19H25ClN6ODegré de pureté :98.13% - 98.91%Couleur et forme :PowderMasse moléculaire :388.89Quinacrine dihydrochloride
CAS :Quinacrine dihydrochloride (Mepacrine dihydrochloride) is the dihydrochloride salt of the 9-aminoacridine derivative quinacrine with potential antineoplasticFormule :C23H30CLN3O·2HClDegré de pureté :98.24% - 99.72%Couleur et forme :Yellow Crystals Or PowderMasse moléculaire :472.88Avermectin B1
CAS :Avermectin B1 is served as anthelmintic and insecticide.Formule :C48H72O14Degré de pureté :mixture - mixtureCouleur et forme :White PowderMasse moléculaire :873.09ICCB-19 hydrochloride
CAS :ICCB-19 hydrochloride (ICCB-19 HCl) is an inhibitor of TRADD (TNFRSF1A Associated Via Death Domain). It binds to a pocket on the TRADD-N.Formule :C12H22ClN3OSDegré de pureté :99.30%Couleur et forme :SolidMasse moléculaire :291.84Ref: TM-T8931L
5mg35,00€10mg52,00€25mg96,00€50mg145,00€100mg210,00€200mg313,00€500mg495,00€1mL*10mM (DMSO)35,00€Sertindole
CAS :Sertindole, atypical antipsychotic, targets D2, 5-HT1D, 5-HT2A, 5-HT2C receptors (Kds: 2.7, 20, 0.14, 6 nM).Formule :C24H26ClFN4ODegré de pureté :99.74%Couleur et forme :Off-White To Pale Yellow SolidMasse moléculaire :440.94Ruxolitinib
CAS :Ruxolitinib (INCB018424) is a JAK1/2 inhibitor (IC50=3.3/2.8 nM) that is potent and selective.Formule :C17H18N6Degré de pureté :100% - 99.99%Couleur et forme :SolidMasse moléculaire :306.36Ref: TM-T1829
5mg58,00€10mg74,00€25mg92,00€50mg116,00€100mg155,00€200mg245,00€500mg414,00€1mL*10mM (DMSO)65,00€Acacetin
CAS :Acacetin (5,7-Dihydroxy-4'-methoxyflavone) is an O-methylated flavone found in various plants, shows antinociceptive, anti-inflammatory, and antioxidantFormule :C16H12O5Degré de pureté :96.26% - ≥98%Couleur et forme :Pale-Yellow NeedlesMasse moléculaire :284.26WYE-354
CAS :WYE-354 is a selective mTOR inhibitor (IC50=5 nM), targeting mTORC1/C2 over PI3Kα (>100x) and PI3Kγ (>500x), sparing P-AKT(T308).Formule :C24H29N7O5Degré de pureté :97.86% - 99.61%Couleur et forme :SolidMasse moléculaire :495.53N6-Isopentenyladenosine
CAS :N6-Isopentenyladenosine, an end product of the mevalonate pathway, is an autophagy inhibitor with anti-melanoma activity.Formule :C15H21N5O4Degré de pureté :99.51%Couleur et forme :SolidMasse moléculaire :335.36Chloramphenicol
CAS :Chloramphenicol (Chloromycetin) is a broad-spectrum antibiotic that inhibits the biosynthesis of bacterial proteins. Cost-effective and quality-assured.Formule :C11H12Cl2N2O5Degré de pureté :99.6% - 99.84%Couleur et forme :Needles Or Elongated Plates From Water Or Ethylene Dichloride SolidMasse moléculaire :323.13EB-42486
CAS :EB-42486 is an effective and highly selective inhibitor of G2019S-LRRK2 with an IC50 < 0.2 nM.Formule :C22H22N8ODegré de pureté :98.06%Couleur et forme :SolidMasse moléculaire :414.46Ref: TM-T39972
1mg70,00€2mg93,00€5mg156,00€10mg226,00€25mg409,00€50mg610,00€100mg867,00€200mg1.159,00€1mL*10mM (DMSO)170,00€Sanguinarine
CAS :Sanguinarine (Pseudochelerythrine) is a specific inhibitor of Rac1b with anti-microbial, anti-oxidant and anti-inflammatory properties.Formule :C20H14NO4Degré de pureté :99.04% - 99.18%Couleur et forme :SolidMasse moléculaire :332.33Regorafenib Hydrochloride
CAS :Regorafenib HCl (BAY73-4506) is an oral inhibitor targeting angiogenic, stromal, and cancer kinases with strong antitumor effects.Formule :C21H16Cl2F4N4O3Degré de pureté :99.56%Couleur et forme :SolidMasse moléculaire :519.289-ING-41
CAS :9-ING-41 is a glycogen synthase kinase-3 inhibitor.Formule :C22H13FN2O5Degré de pureté :99.32%Couleur et forme :SolidMasse moléculaire :404.35Ref: TM-T14066
1mg49,00€2mg70,00€5mg99,00€10mg163,00€25mg325,00€50mg472,00€100mg705,00€1mL*10mM (DMSO)116,00€N-Benzyllinolenamide
CAS :N-Benzyllinolenamide is a natural product. It is an inhibitor of fatty acid amide hydrolase (FAAH, IC50 of 41.8 μM).Formule :C25H37NODegré de pureté :98.00% - 99.92%Couleur et forme :SolidMasse moléculaire :367.57Ref: TM-TN1965
1mg88,00€5mg187,00€10mg281,00€25mg475,00€50mg692,00€100mg935,00€200mg1.264,00€1mL*10mM (DMSO)188,00€Omipalisib
CAS :Omipalisib (GSK2126458) is a small-molecule pyridylsulfonamide inhibitor of phosphatidylinositol 3-kinase (PI3K) with potential antineoplastic activity.Formule :C25H17F2N5O3SDegré de pureté :98% - 99.8%Couleur et forme :SolidMasse moléculaire :505.5Melatonin
CAS :Melatonin (Melatonine) is a natural hormone that activates melatonin receptors. Melatonin regulates the biological clock. Cost-effective and quality-assured.Formule :C13H16N2O2Degré de pureté :98% - 99.79%Couleur et forme :Pale Yellow Leaflets From Benzene SolidMasse moléculaire :232.28Triclosan
CAS :Triclosan (Irgasan) is an antibacterial and antifungal agent.Formule :C12H7Cl3O2Degré de pureté :99.63%Couleur et forme :White Solid CrystallineMasse moléculaire :289.54Galangin
CAS :Galangin (Norizalpinin) is an agonist/antagonist of the arylhydrocarbon receptor, and also shows inhibition of CYP1A1 activity.Formule :C15H10O5Degré de pureté :98.24% - 99.93%Couleur et forme :Yellowish Needle-Like CrystalMasse moléculaire :270.24Briciclib
CAS :Briciclib (ON 014185) is a small molecule that suppresses cyclin D1 accumulation in Y cells.Formule :C19H23O10PSDegré de pureté :98% - 99.84%Couleur et forme :SolidMasse moléculaire :474.42Ref: TM-T3207
1mg47,00€2mg57,00€5mg88,00€10mg126,00€25mg250,00€50mg376,00€100mg560,00€500mg1.216,00€1mL*10mM (DMSO)87,00€PFE-360
CAS :PFE-360 (PF-06685360) is a potent and selective inhibitor of LRRK2 kinase (IC50: 2.3 nM in vivo).Formule :C16H16N6ODegré de pureté :98.14% - 99.73%Couleur et forme :SolidMasse moléculaire :308.34Sorafenib
CAS :Sorafenib (Bay 43-9006) is a multikinase inhibitor that inhibits Raf-1, B-Raf, VEGFR2, VEGFR3, VEGFR4, PDGFRβ, FLT3, c-Kit, and others (IC50=6/22/90/15/20/20/57Formule :C21H16ClF3N4O3Degré de pureté :98% - 99.89%Couleur et forme :SolidMasse moléculaire :464.82Dasatinib
CAS :Dasatinib (BMS-354825) is a tyrosine kinase inhibitor that inhibits Src and Bcr-Abl (Ki=16/30 pM) and is orally active and ATP-competitive.Formule :C22H26ClN7O2SDegré de pureté :99.59% - 99.86%Couleur et forme :Pale-Yellow SolidMasse moléculaire :488.01Bacilotetrin C analogue
Bacilotetrin C analogue is a variant of Bacilotetrin C. It exhibits cytotoxicity against the triple-negative breast cancer cell line MDA-MB-231, with an IC50 of 0.48 μM. This compound induces autophagy (autophagy) in tumor cells and possesses antitumor activity.Formule :C44H76N6O10Couleur et forme :SolidMasse moléculaire :849.11Indophagolin
CAS :Indophagolin: autophagy inhibitor, IC50 140 nM; blocks P2X4, P2X1, P2X3 receptors, IC50s 2.71, 2.40, 3.49 μM.Formule :C19H15BrClF3N2O3SDegré de pureté :99.76%Couleur et forme :SolidMasse moléculaire :523.75Ref: TM-T8946
1mg58,00€5mg111,00€10mg170,00€25mg284,00€50mg393,00€100mg552,00€200mg748,00€1mL*10mM (DMSO)129,00€Hesperetin
CAS :Hesperetin belongs to the flavanone class of flavonoids.Formule :C16H14O6Degré de pureté :99.27%Couleur et forme :SolidMasse moléculaire :302.28SN-38
CAS :SN-38 (NK012) is the active metabolite of Irinotecan, a DNA topoisomerase I (Topo I) inhibitor, which inhibits DNA and RNA synthesis (IC50=0.077/1.3 μM).Formule :C22H20N2O5Degré de pureté :98% - 99.97%Couleur et forme :Light-Yellow SolidMasse moléculaire :392.44,4'-Dimethoxychalcone
CAS :4,4'-Dimethoxychalcone (4,4-Dimethoxychalcone) is a natural product.Formule :C17H16O3Degré de pureté :99.57%Couleur et forme :SolidMasse moléculaire :268.31Linagliptin
CAS :Linagliptin (BI 1356) is a potent, orally bioavailable dihydropurinedione-based inhibitor of dipeptidyl peptidase 4 (DPP-4), with hypoglycemic activity.Formule :C25H28N8O2Degré de pureté :99.15% - 99.95%Couleur et forme :SolidMasse moléculaire :472.54FTO-IN-10
FTO-IN-10 (compound 7), a potent inhibitor of the human demethylase FTO (fat mass and obesity-associated protein), exhibits an IC50 of 4.5 μM.Degré de pureté :98%Couleur et forme :Odour SolidBIX 02565
CAS :BIX 02565 is a potent inhibitor of ribosomal S6 kinase 2 (RSK2, IC50: 1.1 nM).Formule :C26H30N6O2Degré de pureté :97.44% - 99.61%Couleur et forme :SolidMasse moléculaire :458.56Felodipine
CAS :Felodipine (CGH-869) is a longlasting 1, 4-dihydropyridine calcium channel repressor.Formule :C18H19Cl2NO4Degré de pureté :99.91%Couleur et forme :SolidMasse moléculaire :384.25Ref: TM-T0145
5mg51,00€10mg82,00€25mg124,00€50mg180,00€100mg264,00€200mg398,00€500mg647,00€1mL*10mM (DMSO)90,00€(+)-JQ-1
CAS :(+)-JQ-1 (JQ1) is a BET bromine domain inhibitor that inhibits BRD4 (1/2) (IC50=77/33 nM) with specificity and reversibility.Formule :C23H25ClN4O2SDegré de pureté :97.57% - ≥95%Couleur et forme :SolidMasse moléculaire :456.99Ref: TM-T2110
1mg35,00€2mg44,00€5mg60,00€10mg79,00€25mg96,00€50mg144,00€100mg188,00€200mg283,00€500mg512,00€1mL*10mM (DMSO)66,00€ISRIB (trans-isomer)
CAS :ISRIB (trans-isomer) is a potent inhibitor of PERK that rescues protein translation and prevents SG formation in the presence of P-eIF2α. Cost effective and quality assured.Formule :C22H24Cl2N2O4Degré de pureté :97.86% - 99.27%Couleur et forme :SolidMasse moléculaire :451.34Glibenclamide
CAS :Glibenclamide (Glyburide) is an antidiabetic sulfonylurea derivative with actions similar to those of chlorpropamide.Formule :C23H28ClN3O5SDegré de pureté :99.05% - 99.75%Couleur et forme :SolidMasse moléculaire :494Binimetinib
CAS :Binimetinib (ARRY-162) is a MEK1/2 inhibitor (IC50=12 nM) with selective and oral activity. Binimetinib has antitumor activity. Cost-effective and quality-assured.Formule :C17H15BrF2N4O3Degré de pureté :100% - 99%Couleur et forme :SolidMasse moléculaire :441.23Hydroxychloroquine sulfate
CAS :Hydroxychloroquine sulfate (Acidum iopanoicum) inhibits plasmodial heme polymerase.Formule :C18H26ClN3O·H2SO4Degré de pureté :98.92% - 99.88%Couleur et forme :Odorless SolidMasse moléculaire :433.95AZD1208
CAS :AZD1208 is a novel, orally bioavailable, highly selective PIM kinase inhibitor with single nanomolar potency against all three PIM kinases.Formule :C21H21N3O2SDegré de pureté :97.24% - 99.83%Couleur et forme :SolidMasse moléculaire :379.48Ref: TM-T2300
2mg38,00€5mg51,00€10mg74,00€25mg118,00€50mg213,00€100mg378,00€200mg495,00€500mg792,00€1mL*10mM (DMSO)57,00€Sildenafil citrate
CAS :Sildenafil citrate, a PDE5 inhibitor for erectile dysfunction and occasionally pulmonary hypertension.Formule :C28H38N6O11SDegré de pureté :99.59% - 99.97%Couleur et forme :White SolidMasse moléculaire :666.7Piperine
CAS :Piperine (Bioperine) , a alkaloid, has been used in trials studying the treatment of multiple myeloma and deglutition disorders.Formule :C17H19NO3Degré de pureté :100% - 97.79%Couleur et forme :SolidMasse moléculaire :285.34Cyclovirobuxine D
CAS :Cyclovirobuxine D (Bebuxine) is extracted from Buxus microphylla.Formule :C26H46N2ODegré de pureté :97.78% - 98%Couleur et forme :SolidMasse moléculaire :402.66Embelin
CAS :Embelin (Embelic acid), isolated from the Japanese Ardisia herb, is an inhibitor of the X-linked inhibitor of apoptosis (IC50: 4.1 uM).Formule :C17H26O4Degré de pureté :97.07% - 99.88%Couleur et forme :SolidMasse moléculaire :294.39PTC-209 hydrobromide
CAS :PTC-209 hydrobromide (PTC-209 HBr) is the hydrobromide salt of PTC-209, which is a potent and selective BMI-1 inhibitor with IC50 of 0.5 μM, and results inFormule :C17H13Br2N5OS·HBrDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :576.1TWS119
CAS :TWS119 is a GSK-3β inhibitor; capable of inducing neuronal differentiationFormule :C18H14N4O2Degré de pureté :98.02% - 99.13%Couleur et forme :SolidMasse moléculaire :318.33Skatole
CAS :Skatole (3-Methyl-1H-indole), produced by bacteria, regulates intestinal epithelial cellular functions through activating aryl hydrocarbon receptors and p38.Formule :C9H9NDegré de pureté :99.74%Couleur et forme :Leaves From Petroleum Ether; White-Brown Scales SolidMasse moléculaire :131.17Ginsenoside F2
CAS :Ginsenoside F2 halts breast CSCs growth, induces apoptosis via intrinsic pathway and impairs mitochondria.Formule :C42H72O13Degré de pureté :99.04% - 99.3%Couleur et forme :SolidMasse moléculaire :785.01Ref: TM-T3916
1mg35,00€5mg69,00€10mg88,00€25mg144,00€50mg205,00€100mg303,00€500mg735,00€1mL*10mM (DMSO)97,00€CD437
CAS :CD437 (AHPN) is a specifc Retinoic Acid Receptor γ (RARγ) agonist.Formule :C27H26O3Degré de pureté :98.79% - 99.63%Couleur et forme :SolidMasse moléculaire :398.49Triptonide
CAS :Triptonide treats autoimmune diseases, has antileukemic/tumor effects, is anti-inflammatory, and boosts IL-37.Formule :C20H22O6Degré de pureté :99.11% - 99.64%Couleur et forme :White Crystalline PowderMasse moléculaire :358.39Ref: TM-T5S1058
1mg56,00€5mg114,00€10mg166,00€25mg283,00€50mg454,00€100mg660,00€200mg917,00€1mL*10mM (DMSO)140,00€Hoechst 33342 trihydrochloride
CAS :Hoechst 33342 trihydrochloride (bisBenzimide H 33342 trihydrochloride;HOE 33342 trihydrochloride) is a membrane permeant DNA stain with blue fluorescence.Formule :C27H31Cl3N6ODegré de pureté :98.73% - ≥98%Couleur et forme :SolidMasse moléculaire :561.93TA-02
CAS :TA-02 is a p38 MAPK inhibitor with IC50 of 20 nM.TA-02 especially inhibits TGFBR-2.Formule :C20H13F2N3Degré de pureté :99.35% - 99.79%Couleur et forme :SolidMasse moléculaire :333.33Ref: TM-T4646
5mg39,00€10mg58,00€25mg104,00€50mg160,00€100mg244,00€500mgÀ demander1mL*10mM (DMSO)43,00€Rosuvastatin
CAS :Rosuvastatin (ZD4522) is an inhibitor of HMG-CoA reductase (HMGCR). Rosuvastatin has hypolipidemic and antiatherosclerotic effects. Cost-effective and quality-assured.Formule :C22H28FN3O6SDegré de pureté :95.24% - 99.8%Couleur et forme :SolidMasse moléculaire :481.54Imiquimod
CAS :Imiquimod (R 837) is an immune response modifier that acts as a toll-like receptor 7 agonist.Formule :C14H16N4Degré de pureté :100% - 99.62%Couleur et forme :White To Off White Crystalline PowderMasse moléculaire :240.3SAFit2
CAS :SAFit2 is a highly potent and selective inhibitor of fk506 binding protein 51 (FKBP51).Cost-effective and quality-assuredFormule :C46H62N2O10Degré de pureté :98.24% - 99.96%Couleur et forme :SolidMasse moléculaire :802.99Ref: TM-T16836
1mg92,00€5mg197,00€10mg296,00€25mg504,00€50mg717,00€100mg938,00€200mg1.320,00€1mL*10mM (DMSO)261,00€Azithromycin
CAS :Azithromycin (CP 62993) is an antibiotic by inhibiting protein synthesis, used for the treatment of bacterial infections.Formule :C38H72N2O12Degré de pureté :99.88% - 99.9%Couleur et forme :White To Off-White Solid CrystallineMasse moléculaire :748.98Wogonin
CAS :Wogonin (Vogonin) is a cell-permeable and orally available flavonoid that displays anti-inflammatory and anticancer properties.Formule :C16H12O5Degré de pureté :98% - 99.8%Couleur et forme :Yellow CrystalMasse moléculaire :284.26Oxybenzone
CAS :Oxybenzone (Eusolex 4360) is an organic compound used in sunscreens. It is a derivative of benzophenone.Formule :C14H12O3Degré de pureté :99.70%Couleur et forme :Colorless Crystals Physical Description White To Off-White Or Light Yellow Powder (Ntp 1992)Masse moléculaire :228.24Glucosamine
CAS :Glucosamine (Chitosamine) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids.Formule :C6H13NO5Degré de pureté :99.80% - 99.80%Couleur et forme :CoaMasse moléculaire :179.17Imatinib Mesylate
CAS :Imatinib Mesylate (STI-571) is a tyrosine kinase receptor inhibitor with antineoplastic activity (IC50s: 0.6 μM, 0.1 μM and 0.1 μM for v-Abl, c-Kit and PDGFR,Formule :C29H31N7O·CH4SO3Degré de pureté :100% - 99.97%Couleur et forme :White Crystalline PowderMasse moléculaire :589.71Polyphyllin G
CAS :Polyphyllin G (Polyphyllin VII), the the main member of polyphyllin family, shows strong anticancer activity against several carcinomas.Formule :C51H84O22Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1049.21PFK-158
CAS :PFK-158 is an effective and specific inhibitor PFKFB3.Formule :C18H11F3N2ODegré de pureté :95.49% - 98.58%Couleur et forme :SolidMasse moléculaire :328.29Ref: TM-T3105
1mg35,00€2mg48,00€5mg70,00€10mg96,00€25mg173,00€50mg273,00€100mg432,00€1mL*10mM (DMSO)77,00€Adezmapimod
CAS :Adezmapimod (SB 203580) is a p38 MAPK inhibitor (IC50=0.3-0.5 μM) that is selective and ATP-competitive.Formule :C21H16FN3OSDegré de pureté :99.42% - 99.87%Couleur et forme :White SolidMasse moléculaire :377.43UNC1999
CAS :UNC1999 is a orally bioavailable, effective and specific inhibitor of EZH2 (IC50=2 nM) and EZH1 (IC50=45).Formule :C33H43N7O2Degré de pureté :100% - 99.49%Couleur et forme :SolidMasse moléculaire :569.74Ref: TM-T3057
1mg37,00€2mg52,00€5mg71,00€10mg97,00€25mg177,00€50mg286,00€100mg515,00€500mg1.130,00€1mL*10mM (DMSO)89,00€D-glutamine
CAS :D-glutamine, an D type stereoisomer of glutamine, is one of the 20 amino acids which is encoded by the standard genetic code.Formule :C5H10N2O3Degré de pureté :99.99%Couleur et forme :White Or Off-White PowderMasse moléculaire :146.14MLi-2
CAS :MLi-2: Novel, potent CNS-active LRRK2 inhibitor; IC50s: 0.76nM in vitro, 1.4nM cellular, 3.4nM binding.Formule :C21H25N5O2Degré de pureté :98.96%Couleur et forme :SolidMasse moléculaire :379.46Ref: TM-T16115
1mg66,00€2mg96,00€5mg133,00€10mg197,00€25mg435,00€50mg658,00€100mg937,00€1mL*10mM (DMSO)142,00€Lycorine hydrochloride
CAS :Lycorine hydrochloride (Narcissine hydrochloride) is VE-cadherin inhibitor,and has IC50 of 1.2μM in Hey1B cell.It is an HCV inhibitor with strong activity.Formule :C16H18ClNO4Degré de pureté :99.45% - 99.49%Couleur et forme :Fine Crystal PowderMasse moléculaire :323.77Regorafenib
CAS :Regorafenib (BAY 73-4506) is a multi-targeted receptor tyrosine kinase inhibitor that inhibits RET, C-RAF, VEGFR2, c-Kit, VEGFR1, and PDGFRβ and is orallyFormule :C21H15ClF4N4O3Degré de pureté :98% - 99.95%Couleur et forme :SolidMasse moléculaire :482.82Ref: TM-T1792
5mg35,00€10mg51,00€25mg80,00€50mg96,00€100mg144,00€200mg185,00€500mg309,00€1mL*10mM (DMSO)57,00€Erlotinib
CAS :Erlotinib (NSC-718781) is an EGFR inhibitor (IC50: 2 nM). It is used for the treatment of non-small cell lung cancer.Formule :C22H23N3O4Degré de pureté :98.19% - 99.98%Couleur et forme :White To Off-White PowderMasse moléculaire :393.44Butein
CAS :Butein is a cAMP-specific PDE inhibitor, protein tyrosine kinase inhibitor, and SIRT1 activator.Cost-effective and quality-assured.Formule :C15H12O5Degré de pureté :100% - 99.85%Couleur et forme :SolidMasse moléculaire :272.25Ref: TM-T6427
1mg43,00€2mg56,00€5mg88,00€10mg106,00€25mg213,00€50mg344,00€100mg550,00€1mL*10mM (DMSO)87,00€Genistein
CAS :Genistein (NPI 031L) is a natural soy isoflavone, a multi-targeted tyrosine kinase inhibitor. Genistein has antitumor effects. Cost effective and quality assured.Formule :C15H10O5Degré de pureté :98.22% - 99.69%Couleur et forme :Rectangular Or Six-Sided Rods From 60% Alcohol Dendritic Needles From Ether SolidMasse moléculaire :270.24KU-55933
CAS :KU-55933 (ATM Kinase Inhibitor) is an ATM inhibitor that is selective and ATP-competitive. KU-55933 has antitumor effects. Cost-effective and quality-assured.Formule :C21H17NO3S2Degré de pureté :100% - 99.80%Couleur et forme :SolidMasse moléculaire :395.49Arglabin
CAS :Arglabin ((+)-Arglabin) is a natural product isolated from Artemisia glabella, is a NLRP3 inflammasome inhibitor, has anti-atherogenic and anticancer effects.Formule :C15H18O3Degré de pureté :99.62% - 99.62%Couleur et forme :SolidMasse moléculaire :246.3Ref: TM-TQ0165
1mg104,00€5mg240,00€10mg360,00€25mg520,00€50mg692,00€100mg1.035,00€1mL*10mM (DMSO)310,00€Lys05
CAS :Lys05, a potent autophagy inhibitor, outperforms HCQ in cancer treatment, showing promise for drug development.Formule :C23H26Cl5N5Degré de pureté :99.13% - 99.45%Couleur et forme :SolidMasse moléculaire :549.75Salubrinal
CAS :Salubrinal, a phosphatases (PP1) inhibitor(IC50=1.7 μM), exhibits function on the eukaryotic translation initiation factor 2 subunit (eIF2α).Formule :C21H17Cl3N4OSDegré de pureté :100% - 98.25%Couleur et forme :SolidMasse moléculaire :479.81Ref: TM-T3045
2mg42,00€5mg62,00€10mg93,00€25mg163,00€50mg274,00€100mg465,00€500mg1.035,00€1mL*10mM (DMSO)67,00€yangonin
CAS :Yangonin (Y100550) is a novel CB1 receptor ligand with affinity for human recombinant CB1 receptors.Formule :C15H14O4Degré de pureté :98.82% - 99.55%Couleur et forme :Pale Yellow PowderMasse moléculaire :258.27Ref: TM-T3S0738
1mg70,00€5mg135,00€10mg207,00€25mg349,00€50mg515,00€100mg735,00€1mL*10mM (DMSO)177,00€Rupatadine Fumarate
CAS :Rupatadine Fumarate (Rinialer) (UR-12592 Fumarate) is a potent dual PAF/H1 antagonist with Ki of 0.55/0.1 uM.Formule :C26H26ClN3·C4H4O4Degré de pureté :99.86%Couleur et forme :White Or Almost-White PowderMasse moléculaire :532.03BRD4 degrader-5
BRD4 degrader-5 (Compound 23) is a protein degrader utilizing a hydrophobic tag (HyTag) that targets BRD4 for degradation through endoplasmic reticulum stress and the autophagy-lysosome pathway (DC50 = 24.7 μM). It also inhibits the proliferation of 4T1 cancer cells, with an IC50 of 20.6 μM.Formule :C35H42ClN7O2SCouleur et forme :SolidMasse moléculaire :660.27Sulfasalazine
CAS :Sulfasalazine (Azulfidine) is a synthetic salicylic acid derivative. Sulfasalazine induces ferroptosis and inhibits NF-κB. Cost effective and quality assured.Formule :C18H14N4O5SDegré de pureté :98.00% - 99.28%Couleur et forme :Minute Brownish-Yellow CrystalsMasse moléculaire :398.39Fasudil
CAS :Fasudil (HA-1077) is a potent inhibitor of ROCK1, PKA, PKC, and MLCK.Formule :C14H17N3O2SDegré de pureté :99.79% - 99.84%Couleur et forme :SolidMasse moléculaire :291.37Pirarubicin
CAS :Pirarubicin (Theprubicin), an anthracycline antibiotic, inhibits DNA/RNA synthesis and is used as an antineoplastic.Formule :C32H37NO12Degré de pureté :97.61% - 98.27%Couleur et forme :Red Crystalline PowderMasse moléculaire :627.64Ponatinib
CAS :Ponatinib (AP24534) is an orally available, multitargeted kinase inhibitor (IC50s: 0.37/1.1/1.5/2.2/5.4 nM for Abl, PDGFRα, VEGFR2, FGFR1, and Src, respectivelyFormule :C29H27F3N6ODegré de pureté :98% - 99.60%Couleur et forme :SolidMasse moléculaire :532.56PR-619
CAS :PR-619 (2,6-Diamino-3,5-dithiocyanopyridine) is a DUB inhibitor. PR-619 induces endoplasmic reticulum stress and activates autophagy. Cost-effective and quality-assured.Formule :C7H5N5S2Degré de pureté :100% - 99.10%Couleur et forme :SolidMasse moléculaire :223.28Cabergoline
CAS :Cabergoline (FCE-21336), an ergot-derived dopamine D2-like agonist, targets D2/D3/5-HT2B, normalizes prolactin, controls pituitary tumors.Formule :C26H37N5O2Degré de pureté :99.86%Couleur et forme :White Crystalline SolidMasse moléculaire :451.6Pemetrexed disodium hemipenta hydrate
CAS :Pemetrexed disodium hemipenta hydrate (LY-231514 Disodium Hydrate) is a new-type antifolate and antimetabolite for TS, DHFR, and GARFT.Formule :C20H21N5O6·2NaH2ODegré de pureté :98.76%Couleur et forme :SolidMasse moléculaire :518.43Omeprazole
CAS :Omeprazole (Losec) is a proton pump inhibitor (PPI), Omeprazole(Losec) is a potent brain penetrant neutral sphingomyelinase (N-SMase) inhibitor.Formule :C17H19N3O3SDegré de pureté :98.43% - 98.48%Couleur et forme :White SolidMasse moléculaire :345.42Vistusertib
CAS :Vistusertib (AZD2014) is an orally bioavailable inhibitor of the mammalian target of rapamycin (mTOR) with potential antineoplastic activity.Formule :C25H30N6O3Degré de pureté :97.08% - 99.06%Couleur et forme :SolidMasse moléculaire :462.54Ref: TM-T1961
1mg37,00€5mg74,00€10mg117,00€25mg173,00€50mg236,00€100mg378,00€200mg558,00€1mL*10mM (DMSO)84,00€Juglanin
CAS :Juglanin is a JNK activator. Juglanin with inflammation and anti-tumor activities. It can induce apoptosis and autophagy on human breast cancer cells.Formule :C20H18O10Degré de pureté :98.8% - 99.33%Couleur et forme :SolidMasse moléculaire :418.35Citalopram hydrobromide
CAS :Citalopram hydrobromide (XU-62-320) , a selective serotonin reuptake inhibitor (SSRI), selectively inhibits the CNS neuronal reuptake of serotonin, therebyFormule :C20H22BrFN2ODegré de pureté :99.81%Couleur et forme :White Crystalline PowderMasse moléculaire :405.304Linifanib
CAS :Linifanib (AL-39324) (ABT-869) is a novel, potent ATP-competitive VEGFR/PDGFR inhibitor for KDR (IC50: 4 nM), CSF-1R (IC50: 3 nM), Flt-1/3 (IC50: 3/4 nM) andFormule :C21H18FN5ODegré de pureté :98% - 98.24%Couleur et forme :SolidMasse moléculaire :375.4Ref: TM-T2514
5mg50,00€10mg85,00€25mg126,00€50mg188,00€100mg274,00€200mg505,00€500mg815,00€1mL*10mM (DMSO)52,00€Metformin hydrochloride
CAS :Metformin hydrochloride (1,1-Dimethylbiguanide hydrochloride) is an AMPK activator. Metformin is used in type 2 diabetes research. Cost-effective and quality-assured.Formule :C4H12ClN5Degré de pureté :97.53% - 99.00%Couleur et forme :White Or Almost White Crystals Solid CrystallineMasse moléculaire :165.63HG-10-102-01
CAS :HG-10-102-01 is an inhibitor of leucine-rich repeat kinase 2 (LRRK2, IC50 of 20.3 nM).Formule :C17H20ClN5O3Degré de pureté :99.59%Couleur et forme :SolidMasse moléculaire :377.83Ref: TM-T7196
2mg38,00€5mg58,00€10mg94,00€25mg170,00€50mg264,00€100mg380,00€200mg540,00€1mL*10mM (DMSO)65,00€Quercitrin
CAS :Quercitrin (3-rhamnosyl quercetin) is a plant-derived flavonoid compound, displays antioxidant and anti-inflammatory activities.Formule :C21H20O11Degré de pureté :98.4% - 98.89%Couleur et forme :Yellow Crystals From Dil Methanol Or Ethanol SolidMasse moléculaire :448.38Cysmethynil
CAS :Cysmethynil is an indole-based Icmt inhibitor with antitumor activity, induces cell cycle arrest in G1 phase, and can be used for the study of solid tumors.Formule :C25H32N2ODegré de pureté :99%Couleur et forme :SolidMasse moléculaire :376.53Ref: TM-T36082
1mg47,00€2mg60,00€5mg87,00€10mg140,00€25mg274,00€50mg439,00€100mg707,00€500mg1.415,00€Dehydropachymic acid
CAS :Dehydropachymic acid shows antiinflammatory activity.Formule :C33H50O5Degré de pureté :98.22% - 99.78%Couleur et forme :SolidMasse moléculaire :526.75Crizotinib hydrochloride
CAS :Crizotinib hydrochloride (PF-02341066 hydrochloride) is a novel inhibitor of anaplastic lymphoma kinase and c-Met(IC50s of 20 and 8 nM)Formule :C21H23Cl3FN5ODegré de pureté :98.73% - 98.87%Couleur et forme :SolidMasse moléculaire :486.8Ref: TM-T8399
5mg37,00€10mg52,00€25mg82,00€50mg99,00€100mg138,00€200mg171,00€500mg227,00€1mL*10mM (DMSO)59,00€Dactolisib
CAS :Dactolisib (BEZ235) is an orally bioavailable inhibitor of PI3K and mTOR (IC50s: 4 nM/5 nM/7 nM/75 nM, and 20.7 nM for p110α/p110γ/p110δ/p110β and mTOR).Formule :C30H23N5ODegré de pureté :97.64% - 99.85%Couleur et forme :SolidMasse moléculaire :469.54Salirasib
CAS :Salirasib: Competitive PPMTase inhibitor, blocks Ras methylation, potential cancer treatment, Ki=2.6 μM.Formule :C22H30O2SDegré de pureté :99.45%Couleur et forme :SolidMasse moléculaire :358.54Ref: TM-T6163
5mg35,00€10mg52,00€25mg96,00€50mg159,00€100mg221,00€200mg364,00€500mg597,00€1mL*10mM (DMSO)59,00€Apostatin-1
CAS :Apostatin-1 (Apt-1) is a novel TRADD inhibitor. Apostatin-1 can bind to a pocket on the N-terminal TRAF2 binding domain of TRADD.Formule :C19H27N3OSDegré de pureté :100%Couleur et forme :SolidMasse moléculaire :345.5Ref: TM-T9079
1mg37,00€2mg52,00€5mg79,00€10mg119,00€25mg235,00€50mg378,00€100mg560,00€500mg1.216,00€1mL*10mM (DMSO)87,00€Pepstatin
CAS :Pepstatin (Pepsin Inhibitor S 735A) is a specific and orally aspartate protease inhibitor that also inhibits HIV protease activity. Cost effective and quality assured.Formule :C34H63N5O9Degré de pureté :96.74% - 99.94%Couleur et forme :SolidMasse moléculaire :685.89Hydroxyprogesterone caproate
CAS :Hydroxyprogesterone caproate (Delalutin) is a synthetic progestin that activates progesterone receptors and inhibits ovulation.Formule :C27H40O4Degré de pureté :99.70%Couleur et forme :White Or Almost White Crystalline PowerMasse moléculaire :428.6(E)-Daporinad
CAS :(E)-Daporinad (FK866) is a highly specific, non-competitive inhibitor of nicotinamide phosphoribosyltransferase (NAMPT) .Cost-effective and quality-assured.Formule :C24H29N3O2Degré de pureté :100% - 99.96%Couleur et forme :SolidMasse moléculaire :391.51Ref: TM-T2644
2mg43,00€5mg65,00€10mg96,00€25mg188,00€50mg368,00€100mg557,00€500mg1.169,00€1mL*10mM (DMSO)70,00€Glucosamine hydrochloride
CAS :Glucosamine hydrochloride (Chitosamine hydrochloride) is commonly used as a treatment for osteoarthritis, although its acceptance as a medical therapy varies.Formule :C6H13NO5·HClDegré de pureté :99.77%Couleur et forme :White Solid CrystallineMasse moléculaire :215.63SR9009
CAS :SR9009, a REV-ERB agonist, modulates genes and circadian rhythms, reducing fat mass and improving metabolism in obese mice.Formule :C20H24ClN3O4SDegré de pureté :99.53% - 99.8%Couleur et forme :SolidMasse moléculaire :437.94Daunorubicin hydrochloride
CAS :Daunorubicin hydrochloride (Rubidomycin hydrochloride), an anthracycline aminoglycoside antineoplastic, inhibits DNA replication and repair and RNA and proteinFormule :C27H29NO10·HClDegré de pureté :96.21% - 99.53%Couleur et forme :Cancer DrugMasse moléculaire :563.99Ref: TM-T1511
5mg37,00€10mg56,00€25mg92,00€50mg119,00€100mg187,00€200mg298,00€500mg467,00€1mL*10mM (DMSO)63,00€Dorsomorphin
CAS :Dorsomorphin (BML-275) is an AMPK inhibitor (Ki=109 nM) that is selective and ATP-competitive.Formule :C24H25N5ODegré de pureté :98% - 99.06%Couleur et forme :SolidMasse moléculaire :399.49740 Y-P
CAS :740 Y-P (740YPDGFR) is a potent and cell-permeable activator of PI3K.Formule :C141H222N43O39PS3Degré de pureté :98.3% - 99.87%Couleur et forme :SolidMasse moléculaire :3270.7S29434
CAS :S29434 (NMDPEF) is a potent, competitiveinhibitor of quinone reductase 2 (QR2;IC50:5-16nM).Formule :C21H18N4O3Degré de pureté :99.92%Couleur et forme :SolidMasse moléculaire :374.39Telmisartan
CAS :Telmisartan (BIBR 277) is an Angiotensin 2 Receptor Blocker. The mechanism of action of telmisartan is as an Angiotensin 2 Receptor Antagonist.Formule :C33H30N4O2Degré de pureté :99.88% - 99.96%Couleur et forme :White Or Off White Crystalline PowderMasse moléculaire :514.62VO-Ohpic trihydrate
CAS :VO-Ohpic trihydrate (VO-Ohpic) is a potent inhibitor of PTEN (phosphatase and tensin homolog) with IC50 of 35 nM.Formule :C12H9N2O8V·3H2O·HDegré de pureté :100%Couleur et forme :SolidMasse moléculaire :415.2Samotolisib
CAS :Samotolisib (LY3023414) inhibits PI3K, DNA-PK, mTOR; tested for solid tumors including breast and colon cancer.Formule :C23H26N4O3Degré de pureté :98.41% - 99.69%Couleur et forme :SolidMasse moléculaire :406.48Vinblastine sulfate
CAS :Vinblastine sulfate (Vincaleukoblastine sulfate salt) can inhibit the formation of microtubule, it also inhibits nAChR(IC50=8.9 uM).Formule :C46H58N4O9·H2SO4Degré de pureté :97.81% - 99.38%Couleur et forme :White PowderMasse moléculaire :909.06Isodeoxyelephantopin
CAS :Isodeoxyelephantopin can inhibit the growth of various tumor cells.Formule :C19H20O6Degré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :344.36Lonafarnib
CAS :Lonafarnib (Sch66336) is an orally bioavailable FPTase inhibitor for H-ras, K-ras-4B, and N-ras (IC50: 1.9/5.2/2.8 nM).Formule :C27H31Br2ClN4O2Degré de pureté :98% - 99.04%Couleur et forme :SolidMasse moléculaire :638.82Taurine
CAS :Taurine (2-Aminoethanesulfonic acid) is an organic acid widely distributed in animal tissues and is one of the constituents of bile acids. Cost-effective and quality-assured.Formule :C2H7NO3SDegré de pureté :98.05% - 99.81%Couleur et forme :White Crystalline PowderMasse moléculaire :125.15PD146176
CAS :PD146176 (NSC-168807) is an inhibitor of 15-Lipoxygenase (15-LO) , it inhibits rabbit reticulocyte 15-LO with Ki of 197 nM and IC50 of 0.54 μM.Formule :C15H11NSDegré de pureté :98.00%Couleur et forme :SolidMasse moléculaire :237.32SR9011
CAS :SR9011 is a REV-ERB agonist (IC50: 790 nM, REV-ERBα; IC50: 560 nM, REV-ERBβ).Formule :C23H31ClN4O3SDegré de pureté :99.64% - 99.65%Couleur et forme :SolidMasse moléculaire :479.04Tenovin-6
CAS :Tenovin-6 is a p53 transcriptional activity agonist.Formule :C25H34N4O2SDegré de pureté :100% - 97.71%Couleur et forme :SolidMasse moléculaire :454.63Ref: TM-T1818
1mg43,00€2mg56,00€5mg77,00€10mg87,00€25mg157,00€50mg230,00€100mg393,00€500mg930,00€1mL*10mM (DMSO)79,00€NBDHEX
CAS :NBDHEX is a potent inhibitor of glutathione S-transferase P1-1 (GSTP1-1).Formule :C12H15N3O4SDegré de pureté :97.38%Couleur et forme :SolidMasse moléculaire :297.33Gemcitabine hydrochloride
CAS :Gemcitabine hydrochloride (LY 188011 hydrochloride) is a synthetic cytosine nucleoside derivative and an inhibitor of DNA synthesis.Formule :C9H11F2N3O4·HClDegré de pureté :99.28% - 99.98%Couleur et forme :White Crystalline Granular OdorlessMasse moléculaire :299.66Lovastatin
CAS :Lovastatin (MK-803) is an HMG-CoA reductase inhibitor. Lovastatin lowers cholesterol and is used as a lipid-lowering agent. Cost-effective and quality-assured.Formule :C24H36O5Degré de pureté :99.59% - 99.72%Couleur et forme :The Substance Is A White-Yellowish To Yellow Powder Solid PowderMasse moléculaire :404.54CFTR(inh)-172
CAS :CFTR(inh)-172 (CFTR Inhibitor-172) is a voltage-independent, selective CFTR inhibitor.Formule :C18H10F3NO3S2Degré de pureté :98% - 99.72%Couleur et forme :SolidMasse moléculaire :409.4Ref: TM-T2355
1mg35,00€2mg46,00€5mg66,00€10mg97,00€25mg188,00€50mg359,00€100mg530,00€1mL*10mM (DMSO)69,00€Cilengitide TFA
CAS :Cilengitide, αvβ3/αvβ5 inhibitor, IC50: 4.1/79 nM in vitro. 10x selectivity vs. gpIIbIIIa. Phase 2.Formule :C29H41F3N8O9Couleur et forme :SolidMasse moléculaire :702.68Wogonoside
CAS :Wogonoside (Wogonin 7-O-glucuronide) acts as a positive allosteric modulator of the benzodiazepine site of the GABAA receptor.Formule :C22H20O11Degré de pureté :98.24% - 98.66%Couleur et forme :SolidMasse moléculaire :460.39KAN0438757
CAS :KAN0438757 is a selective and potent inhibitor of the metabolic kinase PFKFB3 with an IC50 of 0.19 μM.Formule :C21H18FNO7SDegré de pureté :99.34%Couleur et forme :SolidMasse moléculaire :447.43Ref: TM-T11741
1mg101,00€5mg192,00€10mg306,00€25mg553,00€50mg760,00€100mg1.035,00€1mL*10mM (DMSO)207,00€PF-3845
CAS :PF-3845 is a potent, selective and irreversible FAAH inhibitor with Ki of 230 nM, showing negligible activity against FAAH2.Formule :C24H23F3N4O2Degré de pureté :99.54% - 99.58%Couleur et forme :SolidMasse moléculaire :456.46Ref: TM-T6043
2mg42,00€5mg59,00€10mg97,00€25mg205,00€50mg354,00€100mg560,00€200mg800,00€1mL*10mM (DMSO)59,00€Genipin
CAS :Genipin ((+)-Genipin), an active aglycone derived from an iridoid glycoside called geniposide, is found in the fruit of Gardenia jasminoides Ellis.Formule :C11H14O5Degré de pureté :99.09% - 99.21%Couleur et forme :SolidMasse moléculaire :226.23SAR405
CAS :SAR-405 inhibits PIK3C3/Vps34 (IC50: 1.2 nM, Kd: 1.5 nM), blocks autophagy, and enhances MTOR inhibitor effects on cancer cells.Formule :C19H21ClF3N5O2Degré de pureté :99.42% - 99.79%Couleur et forme :SolidMasse moléculaire :443.85Ref: TM-T12831L
1mg149,00€2mg217,00€5mg368,00€10mg580,00€25mg882,00€50mg1.596,00€1mL*10mM (DMSO)444,00€Azithromycin hydrate
CAS :Azithromycin hydrate (CP-62993 dihydrate) is a semi-synthetic macrolide antibiotic structurally related to erythromycin.Formule :C38H72N2O12·2H2ODegré de pureté :99.83% - 99.92%Couleur et forme :White Or Almost White Crystalline PowderMasse moléculaire :785.03Clioquinol
CAS :Clioquinol: oral, lipophilic copper-binder; halogenated quinoline with antifungal, antiparasitic, and possible antitumor uses.Formule :C9H5ClINODegré de pureté :97.02%Couleur et forme :Brownish-Yellow Bulky Powder Decomposes At 178-179°C Used As A Topical Anti-InfectiveMasse moléculaire :305.5Chelerythrine chloride
CAS :Chelerythrine Chloride is a cell-permeable inhibitor of protein kinase C, competitive with respect to the phosphate acceptor and non-competitive with respect toFormule :C21H18ClNO4Degré de pureté :95% - 99.19%Couleur et forme :Yellow To Orange SolidMasse moléculaire :383.83Clematichinenoside AR
CAS :Clematichinenoside AR is anti-inflammatory, immunosuppressive, and combats arthritis via PI3K/Akt and TNF-α pathways.Formule :C82H134O43Degré de pureté :99.49% - 99.69%Couleur et forme :SolidMasse moléculaire :1807.92ISOGINKGETIN
CAS :ISOGINKGETIN (4',4'''-Dimethylamentoflavone), a compound derived from the leaves of Ginkgo biloba, to up-regulate adiponectin secretion.Formule :C32H22O10Degré de pureté :98% - 99.72%Couleur et forme :SolidMasse moléculaire :566.51SF1670
CAS :SF1670 (PTPase CD45 Inhibitor) is a specific PTEN inhibitor with IC50 of 2 μM.Formule :C19H17NO3Degré de pureté :98.25% - 98.54%Couleur et forme :SolidMasse moléculaire :307.34Ref: TM-T6667
1mg44,00€2mg55,00€5mg88,00€10mg125,00€25mg273,00€50mg500,00€100mg740,00€1mL*10mM (DMSO)97,00€Idelalisib
CAS :Idelalisib (GS-1101) is a small molecule inhibitor of the PI3K catalytic subunit p110δ (IC50: 2.5 nM).Formule :C22H18FN7ODegré de pureté :98% - 99.39%Couleur et forme :SolidMasse moléculaire :415.42Ref: TM-T1894
5mg35,00€10mg50,00€25mg74,00€50mg93,00€100mg108,00€200mg140,00€500mg225,00€1mL*10mM (DMSO)52,00€Veliparib
CAS :Veliparib (ABT-888) (ABT-888) is an orally bioavailable inhibitor of PARP (Kis: 5.2/2.9 nM for PARP1/2). It enhances apoptosis and autophagy.Formule :C13H16N4ODegré de pureté :98.66% - 99%Couleur et forme :SolidMasse moléculaire :244.29Ref: TM-T2591
5mg57,00€10mg81,00€25mg127,00€50mg207,00€100mg331,00€200mg540,00€500mg852,00€1mL*10mM (DMSO)64,00€Vancomycin
CAS :Vancomycin is a glycopeptide antibiotic that exerts its antimicrobial activity by altering the permeability of cell membranes and selectively inhibitingFormule :C66H75Cl2N9O24Degré de pureté :99.24%Couleur et forme :Almost White PowderMasse moléculaire :1449.25Vps34-IN-1
CAS :Vps34-IN-1: potent, selective Vps34 inhibitor, 25 nM IC50, spares class I/II PI3Ks.Formule :C21H24ClN7ODegré de pureté :97.04%Couleur et forme :SolidMasse moléculaire :425.91Ref: TM-T7015
1mg46,00€2mg59,00€5mg93,00€10mg131,00€25mg219,00€50mg350,00€100mg505,00€1mL*10mM (DMSO)92,00€ST-539
CAS :ST-539 is an inhibitor of the deubiquitinating enzyme USP30, with an IC50 of 0.37 μM. It enhances the ubiquitination of mitochondrial proteins and induces mitophagy (autophagy), thereby regulating mitochondrial homeostasis. ST-539 is applicable for research in neurodegenerative diseases.Formule :C30H31N3O4SCouleur et forme :SolidMasse moléculaire :529.65
