Autophagie
Les inhibiteurs de l'autophagie ciblent le processus cellulaire de l'autophagie, qui implique la dégradation et le recyclage des composants cellulaires via les lysosomes. L'autophagie est un mécanisme crucial pour maintenir l'homéostasie cellulaire, mais sa dérégulation est impliquée dans diverses maladies, y compris le cancer, les maladies neurodégénératives et les infections. Les inhibiteurs de l'autophagie peuvent bloquer ce processus, ce qui en fait des outils précieux pour étudier le rôle de l'autophagie dans les maladies et développer des stratégies thérapeutiques. Chez CymitQuimica, nous proposons des inhibiteurs de l'autophagie pour soutenir vos recherches en biologie cellulaire, oncologie et maladies neurodégénératives.
Produits appartenant à la catégorie "Autophagie"
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Panobinostat
CAS :Panobinostat (NVP-LBH589) is a broad-spectrum HDAC inhibitor (IC50=5 nM) with oral activity and non-selectivity.Formule :C21H23N3O2Degré de pureté :97.2% - 99.14%Couleur et forme :Yellow SolidMasse moléculaire :349.43Ref: TM-T2383
5mg38,00€10mg57,00€25mg87,00€50mg105,00€100mg144,00€200mg177,00€500mg364,00€1mL*10mM (DMSO)55,00€Kaempferol
CAS :Kaempferol (Robigenin) is a natural flavonoid and an inverse agonist of ERRα and ERRγ.Formule :C15H10O6Degré de pureté :98% - 99.41%Couleur et forme :Yellow Needles From Alcohol And Water SolidMasse moléculaire :286.24Ref: TM-T2177
1g274,00€5mg52,00€25mg39,00€50mg50,00€100mg64,00€200mg89,00€500mg187,00€1mL*10mM (DMSO)55,00€Meglutol
CAS :Meglutol, a cholesterol and triglyceride reducing antilipemic, hinders key enzymes in cholesterol biosynthesis.Formule :C6H10O5Degré de pureté :99.73% - 99.94%Couleur et forme :SolidMasse moléculaire :162.14Capivasertib
CAS :Capivasertib (AZD5363) is a broad-spectrum AKT inhibitor with inhibitory activity against Akt1, Akt2, and Akt3 (IC50=3/7/7 nM) with oral activity.Formule :C21H25ClN6O2Degré de pureté :97.59% - 99.6%Couleur et forme :SolidMasse moléculaire :428.92Ref: TM-T1920
1mg40,00€2mg52,00€5mg70,00€10mg99,00€25mg168,00€50mg246,00€100mg378,00€200mg610,00€1mL*10mM (DMSO)89,00€Trifluoperazine
CAS :Trifluoperazine (trifluoroperazine) is a Dopamine D2 receptor inhibitor(IC50 : 1.2 nM), and Treatment of schizophrenia.Formule :C21H24F3N3SDegré de pureté :98.3% - 99.46%Couleur et forme :White To Yellowish Crystalline PowderMasse moléculaire :407.5Erlotinib hydrochloride
CAS :Erlotinib hydrochloride (NSC 718781) is an EGFR inhibitor (IC50: 2 nM). It is used for the treatment of non-small cell lung cancer.Formule :C22H23N3O4·HClDegré de pureté :99.78% - 99.85%Couleur et forme :White Or Off-White PowderMasse moléculaire :429.9Oxyresveratrol
CAS :1.Formule :C14H12O4Degré de pureté :98.09% - 99.69%Couleur et forme :Yellow SolidMasse moléculaire :244.24Sodium 4-phenylbutyrate
CAS :Sodium 4-phenylbutyrate (TriButyrate), a transcriptional regulator, reversibly inhibits class I and II HDACs resulting in a global increase in gene expression.Formule :C10H11NaO2Degré de pureté :100% - 99.92%Couleur et forme :SolidMasse moléculaire :186.18Resveratrol
CAS :Resveratrol (SRT 501) is a polyphenolic natural product, a plant antitoxin with antioxidant and chemopreventive activities.Formule :C14H12O3Degré de pureté :99.53% - 99.9%Couleur et forme :Off-White To Tan PowderMasse moléculaire :228.24Dronedarone hydrochloride
CAS :Dronedarone hydrochloride (SR33589) is an amiodarone analog which has an effective and promising treatment for Atrial fibrillation.Formule :C31H44N2O5S·HClDegré de pureté :99.61%Couleur et forme :SolidMasse moléculaire :593.22Ref: TM-T1073
5mg38,00€10mg52,00€25mg87,00€50mg117,00€100mg170,00€200mg250,00€500mg424,00€1mL*10mM (DMSO)55,00€Flavopiridol
CAS :Flavopiridol (Alvocidib) blocks CDK1/2/4/6 by competing with ATP (IC50 ~40 nM); 7.5x selectivity over CDK7; also inhibits EGFR, PKA. In Phase 1/2 trials.Formule :C21H20ClNO5Degré de pureté :97.74% - 99.86%Couleur et forme :SolidMasse moléculaire :401.84SU9516
CAS :SU9516 is a potent CDK2 inhibitor, with an IC50 of 22 nM, and also has inhibitory effects on CDK1 and CDK4, with IC50s of 40 nM and 200 nM, respectively.Formule :C13H11N3O2Degré de pureté :100% - 99.68%Couleur et forme :SolidMasse moléculaire :241.25Ref: TM-T6167
1mg35,00€2mg50,00€5mg73,00€10mg103,00€25mg208,00€50mg376,00€100mg560,00€500mg1.216,00€1mL*10mM (DMSO)74,00€Dehydrocorydaline nitrate
CAS :DHC curbs antibody and cell-mediated allergies, inhibits mitochondrial potential in macrophages, and has antinociceptive, anti-inflammatory effects.Formule :C22H24N2O7Degré de pureté :99.79%Couleur et forme :SolidMasse moléculaire :428.44A-867744
CAS :A-867744 is an effective and selective type II positive allosteric modulator of the α7 nAChR (EC50: 1.0 μM).Formule :C20H19ClN2O3SDegré de pureté :95.66%Couleur et forme :SolidMasse moléculaire :402.89MG-132
CAS :View and buy MG-132 from TargetMol.MG-132 is a potent cell-permeable 26S proteasome inhibitor (IC50: 100 nM). It also inhibits calpain (IC50: 1.2 μM).Cited in 50 publications.Formule :C26H41N3O5Degré de pureté :95% - 99.99%Couleur et forme :White To Off-White PowderMasse moléculaire :475.62Ref: TM-T2154
10mg48,00€25mg88,00€50mg144,00€100mg216,00€200mg376,00€500mg472,00€1mL*10mM (DMSO)47,00€KN-93
CAS :KN-93 is a selective inhibitor of Ca2+/calmodulin-dependent kinase II (CaMKII), competitively blocking CaM binding to the kinase.Formule :C26H29ClN2O4SDegré de pureté :99.78% - 99.86%Couleur et forme :White SolidMasse moléculaire :501.04Ref: TM-T2697
1mg57,00€2mg79,00€5mg113,00€10mg155,00€25mg305,00€50mg378,00€100mg552,00€1mL*10mM (DMSO)127,00€Rhoifolin
CAS :Rhoifolin (Apigenin 7-O-neohesperidoside) is extracted from Turpinia arguya Seem dried leaves.Formule :C27H30O14Degré de pureté :98.11% - 98.87%Couleur et forme :SolidMasse moléculaire :578.52BGT226
CAS :BGT226 (NVP-BGT226) is a novel dual PI3K / mTOR inhibitor, it acts on PI3K α/β/γ with IC50 of 4 nM / 63 nM / 38 nM, respectively.Formule :C28H25F3N6O2Degré de pureté :100% - 98.40%Couleur et forme :SolidMasse moléculaire :534.53Ref: TM-T6072L
1mg52,00€5mg114,00€10mg187,00€25mg411,00€50mg607,00€100mg847,00€1mL*10mM (DMSO)156,00€Corynoxine
CAS :Corynoxine is a tetracyclic oxindole alkaloid isolated from Uncaria macrophylla.Formule :C22H28N2O4Degré de pureté :96.83% - 99.93%Couleur et forme :SolidMasse moléculaire :384.47Talarozole
CAS :Talarozole is an oral RAMBA for treating acne and psoriasis, inhibiting CYP26A1/26B1 with IC50s of 5.4/0.46 nM.Formule :C21H23N5SDegré de pureté :97.51%Couleur et forme :SolidMasse moléculaire :377.5110058-F4
CAS :10058-F4 inhibits c-Myc-Max, blocking c-Myc target gene activation, causing cell-cycle arrest & apoptosis.Formule :C12H11NOS2Degré de pureté :98% - 99.82%Couleur et forme :SolidMasse moléculaire :249.35BGT226 maleate
CAS :BGT226 maleate (NVP-BGT226) is a class I PI3K/mTOR inhibitor for PI3Kα/β/γ (IC50: 4/63/38 nM) .Formule :C28H25F3N6O2·C4H4O4Degré de pureté :97.75% - 98.78%Couleur et forme :SolidMasse moléculaire :650.6Ref: TM-T6072
1mg38,00€5mg77,00€10mg114,00€25mg244,00€50mg359,00€100mg512,00€200mg702,00€1mL*10mM (DMSO)99,00€Schizandrin A
CAS :Schisandrin A, a primary active component extracted from the traditional Eastern medicine Schisandra chinensis, inhibits CYP3A activity, with an IC50 of 6.60 μMFormule :C24H32O6Degré de pureté :99.91%Couleur et forme :SolidMasse moléculaire :416.51Isoalantolactone
CAS :Isoalantolactone (Isohelenin), isolated from Inula spp., can inhibit the growth of several types of Y cells.Formule :C15H20O2Degré de pureté :99.75% - 99.94%Couleur et forme :SolidMasse moléculaire :232.32SMER18
CAS :SMER18, a small molecule enhancer of rapamycin, acts as an mTOR-independent inducer of autophagy and can be used to study neurodegenerative diseases.Formule :C16H14ClNO2Degré de pureté :97.27%Couleur et forme :SolidMasse moléculaire :287.74Ref: TM-T16900
1mg133,00€5mg329,00€10mg472,00€25mg914,00€50mg1.415,00€100mg1.882,00€1mL*10mM (DMSO)360,00€Salvigenin
CAS :Salvigenin is a potent hMAO-A inhibitor, has neuroprotective, antitumor and immunomodulatory effects.Formule :C18H16O6Degré de pureté :99.17% - 99.67%Couleur et forme :SolidMasse moléculaire :328.32Adapalene
CAS :Adapalene (CD271) is a dual RAR and RXR agonist, utilized in the treatment of skin conditions.Formule :C28H28O3Degré de pureté :99.53% - 99.76%Couleur et forme :White To Off-White Crystalline PowderMasse moléculaire :412.52Gemcitabine
CAS :Gemcitabine (LY188011) is a synthetic cytosine nucleoside derivative and an inhibitor of DNA synthesis.Formule :C9H11F2N3O4Degré de pureté :100% - 99.67%Couleur et forme :SolidMasse moléculaire :263.2Ixazomib
CAS :Ixazomib (MLN2238) is a boron-based peptide proteasome inhibitor targeting β5 site (IC50: 3.4 nM), also affecting β1 and β2 sites.Formule :C14H19BCl2N2O4Degré de pureté :98% - 98.92%Couleur et forme :SolidMasse moléculaire :361.03Ref: TM-T2122
1mg48,00€5mg95,00€10mg127,00€25mg259,00€50mg416,00€100mg652,00€200mg922,00€1mL*10mM (DMSO)97,00€Efavirenz
CAS :Efavirenz (DMP 266) is an HIV-1 inhibitor, affecting reverse transcriptase and various cytochrome P450 enzymes.Formule :C14H9ClF3NO2Degré de pureté :99.2% - 99.83%Couleur et forme :White To Slightly Pink Crystalline PowderMasse moléculaire :315.67Ref: TM-T2393
1g404,00€5mg42,00€10mg52,00€25mg71,00€50mg89,00€100mg116,00€500mg273,00€1mL*10mM (DMSO)49,00€Acitretin
CAS :Acitretin (Ro 10-1670) is a second-generation, systemic retinoid that has been used in the treatment of psoriasis.Formule :C21H26O3Degré de pureté :100% - 98.60%Couleur et forme :Crystals From Hexane SolidMasse moléculaire :326.43DMH-1
CAS :DMH-1 is a BMP inhibitor that inhibits ALK1, ALK2, ALK3 and ALK6. DMH-1 promotes pluripotent stem cell differentiation. Cost-effective and quality-assured.Formule :C24H20N4ODegré de pureté :98% - 99.92%Couleur et forme :SolidMasse moléculaire :380.44Alisertib
CAS :Alisertib (MLN 8237) is a specific Aurora A inhibitor (IC50: 1.2 nM). The selectivity of Alisertib(MLN 8237) is >200-fold higher for Aurora A than Aurora B.Formule :C27H20ClFN4O4Degré de pureté :100% - 99.82%Couleur et forme :SolidMasse moléculaire :518.92Ref: TM-T2241
5mg55,00€10mg96,00€25mg155,00€50mg226,00€100mg354,00€200mg454,00€500mg743,00€1mL*10mM (DMSO)63,00€CHIR-99021
CAS :View and buy CHIR-99021 from TargetMol.CHIR-99021 is a GSK-3α/β inhibitor.Cited in 10 publications.Formule :C22H18Cl2N8Degré de pureté :97.94% - ≥95%Couleur et forme :SolidMasse moléculaire :465.34Ref: TM-T2310
2mg43,00€5mg64,00€10mg96,00€25mg160,00€50mg254,00€100mg404,00€200mg603,00€500mg938,00€1mL*10mM (DMSO)70,00€Loperamide hydrochloride
CAS :Loperamide hydrochloride (ADL 2-1294) is a synthetic, piperidine derivative and opioid agonist with antidiarrheal activity.Formule :C29H34Cl2N2O2Degré de pureté :100% - 99.94%Couleur et forme :Crystals Practically Insoluble In WaterMasse moléculaire :513.498Colchicine
CAS :Colchicine (Colcin) is a natural product that is an inhibitor of microtubule polymerization (IC50=3 nM) and blocks microtubule polymerization by binding toFormule :C22H25NO6Degré de pureté :98% - 99.96%Couleur et forme :Pale Yellow Scales Or Powder; Pale Yellow Needles When Crystallized From Ethyl Acetate To Light Used To Treat Gouty Arthritis Pseudogout Sarcoidal Arthritis And Calcific Tendinitis (EpaMasse moléculaire :399.44Lomustine
CAS :Lomustine (NSC-79037) is an alkylating agent of value against both hematologic malignancies and solid tumors.Formule :C9H16ClN3O2Degré de pureté :98.36% - 99.44%Couleur et forme :Solid SolidMasse moléculaire :233.7Tempol
CAS :Tempol (Tanol) is a superoxide scavenger. It has anti-inflammatory, neuroprotective and analgesic effects.Formule :C9H18NO2Degré de pureté :97% - 99.74%Couleur et forme :4-Hydroxy-Tempo Appears As Orange Flakes Solid FlakesMasse moléculaire :172.25Tanespimycin
CAS :Tanespimycin (KOS 953) (17-AAG) is an inhibitor of Hsp90 that selectively inhibits BT474 tumor cell Hsp90 (IC50: 5 nM).Formule :C31H43N3O8Degré de pureté :99.07% - 99.83%Couleur et forme :Dark Purple SolidMasse moléculaire :585.69Sedanolide
CAS :Sedanolide is a natural phthalide first isolated from seed oil of the Umbelliferae family, including celery.Formule :C12H18O2Degré de pureté :97.14% - ≥98%Couleur et forme :SolidMasse moléculaire :194.27α-Thujone
CAS :α-Thujone is an inhibitor of ACh with an IC50 value of 24.7μM.Formule :C10H16ODegré de pureté :98.16% - 98.41%Couleur et forme :Less Or Almost Colorless Liquid With A Menthol- Like Odor (Albert-Puleo 1978; Budavari 1996) Colorless Or Almost Colorless Liquid With A Menthol- Like Odor (Albert-Puleo 1978; Budavari 1996)Masse moléculaire :152.23GSK621
CAS :GSK621 is a specific and potent AMPK activator.Formule :C26H20ClN3O5Degré de pureté :97.02% - 97.05%Couleur et forme :SolidMasse moléculaire :489.91DMOG
CAS :DMOG (Dimethyloxalylglycine), an antagonist of the α-ketoglutarate cofactor, is an inhibitor for HIF prolyl hydroxylase.Formule :C6H9NO5Degré de pureté :80.23% - 99.98%Couleur et forme :SolidMasse moléculaire :175.14ZLN005
CAS :ZLN005 is an effective and tissue-specific transcriptional activator of PGC-1α.Formule :C17H18N2Degré de pureté :100% - 99.8%Couleur et forme :SolidMasse moléculaire :250.34Ref: TM-T1802
5mg37,00€10mg56,00€25mg90,00€50mg170,00€100mg274,00€200mg411,00€500mg653,00€1mL*10mM (DMSO)40,00€Carprofen
CAS :Carprofen (Ridamyl) is a propionic acid derivate and nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, and antipyretic activities.Formule :C15H12ClNO2Degré de pureté :98.99% - 99.65%Couleur et forme :SolidMasse moléculaire :273.71Autogramin-1
CAS :Autogramin-1 potently inhibits starvation-induced autophagy with IC50 of 0.17 μM.Formule :C23H27N5O5SDegré de pureté :97.22% - 98.76%Couleur et forme :SolidMasse moléculaire :485.56Vitexin
CAS :Vitexin: antinociceptive, antispasmodic, antioxidant, affects CYP enzymes, may inhibit cancer metastasis, protects brain.Formule :C21H20O10Degré de pureté :99.16% - 99.64%Couleur et forme :Yellow PowderMasse moléculaire :432.38Lithocholic acid
CAS :Lithocholic acid, a bile acid, aids fat absorption, often paired with glycine/taurine, and promotes bile flow.Formule :C24H40O3Degré de pureté :99.69% - 99.93%Couleur et forme :Hexagonal Leaflets From Alc Prisms From Acetic Acid Powder (Ntp 1992)Masse moléculaire :376.57BIX-01294
CAS :BIX-01294 is an G9a Histone Methyltransferase inhibitor(IC50 : 1.9 μM).Formule :C28H38N6O2Degré de pureté :99.31% - 99.64%Couleur et forme :SolidMasse moléculaire :490.64Ref: TM-T7697
1mg40,00€2mg51,00€5mg85,00€10mg117,00€25mg207,00€50mg350,00€100mg518,00€200mg740,00€1mL*10mM (DMSO)131,00€Colistin sulfate
CAS :Colistin sulfate (Colistin sulfate (1066-17-7 free base)) is a cyclic polypeptide antibiotic from Bacillus colistinus, composed of Polymyxins E1 and E2.Formule :C53H100N16O17SDegré de pureté :≥95%Couleur et forme :PowderMasse moléculaire :1253.51Silibinin
CAS :Silibinin, main component in milk thistle, offers liver protection and shows anti-cancer potential in various human cells.Formule :C25H22O10Degré de pureté :97.98% - 98.35%Couleur et forme :SolidMasse moléculaire :482.44Oroxin B
CAS :Oroxin B (Hypocretin-2) has antioxidant activity.Formule :C27H30O15Degré de pureté :98.22% - 98.33%Couleur et forme :SolidMasse moléculaire :594.52Pictilisib
CAS :Pictilisib (GDC-0941) (GDC-0941) is a potent pan inhibitor of class I catalytic subunits of PI3K (IC50s: 3/33/3/75 nM for p110α/β/δ/γ).Formule :C23H27N7O3S2Degré de pureté :99% - 99.97%Couleur et forme :SolidMasse moléculaire :513.64BC1618
CAS :BC1618 (2-Propanol, 1-[bis(phenylmethyl)amino]-3-[4-(trifluoromethyl)phenoxy]-) is an orally active Fbxo48 inhibitor that stimulates Ampk-dependent signaling.Formule :C24H24F3NO2Degré de pureté :99.95%Couleur et forme :SolidMasse moléculaire :415.45SR12813
CAS :SR12813 (GW 485801) is a pregnane X receptor (PXR) agonist.Formule :C24H42O7P2Degré de pureté :99.43%Couleur et forme :SolidMasse moléculaire :504.53Ipsalazide
CAS :Ipsalazide is a novel salicylazosulfapyridine analog for the treatment of inflammatory bowel disease.Formule :C16H11N3Na2O6Degré de pureté :99.43%Couleur et forme :SolidMasse moléculaire :387.25DBEQ
CAS :DBEQ (JRF 12) is a selective, potent, reversible, and ATP-competitive p97 inhibitor.Formule :C22H20N4Degré de pureté :98.89% - ≥95%Couleur et forme :SolidMasse moléculaire :340.42Ref: TM-T1969
5mg58,00€10mg95,00€25mg180,00€50mg324,00€100mg410,00€200mg607,00€500mg938,00€1mL*10mM (DMSO)59,00€VLX600
CAS :VLX600 is an iron-chelating oxidative phosphorylation (OXPHOS) inhibitor, is a cell-permeable anticancer agent.Formule :C17H15N7Degré de pureté :98.62%Couleur et forme :SolidMasse moléculaire :317.35HDAC10-IN-2 hydrochloride
HDAC10-IN-2 hydrochloride (compound 10c) is an HDAC10 inhibitor with high potency and selectivity, exhibiting an IC50 of 20 nM.Formule :C19H23ClN2O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :346.85Carfilzomib
CAS :Carfilzomib (PR-171) is a proteasome inhibitor that irreversibly binds to the chymotrypsin of the 20S proteasome.Formule :C40H57N5O7Degré de pureté :99.6% - 99.84%Couleur et forme :SolidMasse moléculaire :719.91Shogaol
CAS :6-Shogaol: anti-inflammatory, analgesic, antipyretic, protects cartilage, arrests cancer cell growth, inhibits metastasis.Formule :C17H24O3Degré de pureté :98.26% - 99.39%Couleur et forme :SolidMasse moléculaire :276.37Ref: TM-T6S1699
2mg43,00€5mg62,00€10mg92,00€25mg180,00€50mg283,00€100mg432,00€500mg938,00€1mL*10mM (DMSO)67,00€PF-04457845
CAS :PF-04457845 is a greatly and effctive FAAH inhibitor, and for hFAAH(IC50=7.2±0.63 nM) and rFAAH(IC50=7.4±0.62 nM).Formule :C23H20F3N5O2Degré de pureté :100%Couleur et forme :SolidMasse moléculaire :455.43Ref: TM-T4323
2mg35,00€5mg52,00€10mg88,00€25mg163,00€50mg235,00€100mg419,00€200mg545,00€1mL*10mM (DMSO)58,00€Dansylcadaverine
CAS :Dansylcadaverine (Monodansyl cadaverine) is a fluorescent probe.Formule :C17H25N3O2SDegré de pureté :98.33% - 98.99%Couleur et forme :SolidMasse moléculaire :335.46PF-04691502
CAS :PF-04691502 is a potent and selective inhibitor of PI3K and mTOR kinases with antitumor activity.Formule :C22H27N5O4Degré de pureté :96.27% - ≥95%Couleur et forme :SolidMasse moléculaire :425.48Sinomenine hydrochloride
CAS :Sinomenine hydrochloride (Kukoline hydrochloride) is extracted from Sinomenium Acutum Rehderett Wilson.Formule :C19H24ClNO4Degré de pureté :99.43%Couleur et forme :SolidMasse moléculaire :365.851Fenretinide
CAS :Fenretinide (4-HPR) is an orally-active synthetic retinoid derivative with potential antineoplastic and chemopreventive activities.Formule :C26H33NO2Degré de pureté :98% - 99.72%Couleur et forme :Yellow PowderMasse moléculaire :391.55AZ304
CAS :AZ304 is an ATP-competitive dual BRAF kinase inhibitor, potently inhibits BRAF (WT), BRAF (V600E), and wild type CRAF (IC50s: 79/38/68 nM).Formule :C27H25N5O2Degré de pureté :99.82%Couleur et forme :SolidMasse moléculaire :451.52MHY1485
CAS :MHY1485 is an mTOR activator that is cell-permeable. MHY1485 inhibits autophagosome and lysosome fusion, thereby inhibiting autophagy. Cost-effective and quality-assured.Formule :C17H21N7O4Degré de pureté :100% - 99.6%Couleur et forme :SolidMasse moléculaire :387.39Lapatinib
CAS :Lapatinib (GW572016) is an inhibitor of ErbB2 and EGFR (IC50=9.2/10.8 nM) with oral activity.Formule :C29H26ClFN4O4SDegré de pureté :99.00% - 99.81%Couleur et forme :PowderMasse moléculaire :581.06PHY34
CAS :PHY34 inhibits autophagy at nanomolar potency, with anti-tumor effects on HGSOC in vivo.Formule :C30H30O12Degré de pureté :98.32%Couleur et forme :SolidMasse moléculaire :582.55Ref: TM-T37376
1mg164,00€2mg235,00€5mg369,00€10mg548,00€25mg879,00€50mg1.198,00€100mg1.596,00€500mg3.212,00€JNJ-42165279
CAS :JNJ-42165279 selectively inactivates FAAH without notably affecting other enzymes, ion channels, receptors, or CYPs/hERG at 10 μM.Formule :C18H17ClF2N4O3Degré de pureté :99.88% - 99.89%Couleur et forme :SolidMasse moléculaire :410.8Ref: TM-T3215
2mg46,00€5mg65,00€10mg96,00€25mg170,00€50mg246,00€100mg363,00€200mg512,00€1mL*10mM (DMSO)75,00€Saracatinib
CAS :Saracatinib (AZD0530) (AZD0530) is an effective Src inhibitor (IC50: 2.7 nM), and effective to Lck, Fyn, Lyn, Blk, Fgr and c-Yes.Formule :C27H32ClN5O5Degré de pureté :98% - 99.63%Couleur et forme :SolidMasse moléculaire :542.03ZX-29
CAS :ZX-29: Strong ALK inhibitor; IC50 - ALK 2.1 nM, L1196M 1.3 nM, G1202R 3.9 nM; triggers autophagy; anti-cancer.Formule :C23H28ClN7O3SDegré de pureté :98.32%Couleur et forme :SolidMasse moléculaire :518.03Ref: TM-T13416
1mg92,00€5mg230,00€10mg364,00€25mg620,00€50mg848,00€100mg1.121,00€1mL*10mM (DMSO)296,00€Berbamine dihydrochloride
CAS :Berbamine dihydrochloride (Berbamine), a natural compound derived from the Berberis amurensis plant, has been shown to exhibit antitumor activity in several Ys.Formule :C37H42Cl2N2O6Degré de pureté :95% - 99.38%Couleur et forme :SolidMasse moléculaire :681.65Chloroquine
CAS :Chloroquine: antimalarial, anti-inflammatory, autophagy/TLRs inhibitor, treats arthritis, effective against COVID-19 in vitro. EC50: 1.13 μM.Formule :C18H26ClN3Degré de pureté :99.82% - 99.98%Couleur et forme :White To Slightly Yellow Crystalline Powder SolidMasse moléculaire :319.875-Aminolevulinic acid hydrochloride
CAS :5-Aminolevulinic acid hydrochloride (5-ALA) serves as an intermediate in the body's heme biosynthesis and is the universal precursor of tetrapyrroles.Formule :C5H10ClNO3Degré de pureté :98% - 99.97%Couleur et forme :White To Pale Yellow Crystals OrMasse moléculaire :167.59ULK-101
CAS :ULK-101 is a potent and selective ULK1 inhibitor ( IC50s: 8.3/30 nM for ULK1/ULK2). It can suppress autophagy.Formule :C22H16F4N4OSDegré de pureté :97.55% - 99.66%Couleur et forme :SolidMasse moléculaire :460.45Ref: TM-T5403
1mg111,00€5mg274,00€10mg432,00€25mg747,00€50mg1.121,00€100mg1.510,00€1mL*10mM (DMSO)279,00€Tolvaptan
CAS :Tolvaptan (OPC-41061) is an orally bioavailable, selective, arginine vasopressin receptor 2 (V2, AVPR2) antagonist that can be used to treat hyponatremia.Formule :C26H25ClN2O3Degré de pureté :97% - 99.91%Couleur et forme :SolidMasse moléculaire :448.94ALA-A2 peptide
ALA-A2, a cancer peptide found in α-lactalbumin, selectively kills cancer cells by inducing autophagy (Autophagy). It possesses cell-penetrating properties, allowing it to enter cells effectively without relying on membrane solubilization effects. In A549 lung cancer cells, ALA-A2 demonstrates significant dose-dependent anticancer activity. This peptide shows promise for research in cancer treatment and autophagy regulation.Formule :C67H111N21O19SCouleur et forme :SolidMasse moléculaire :1546.79GCN2iB
CAS :GCN2iB is an ATP-competitive inhibitor of serine/threonine protein kinase, stress-responsive kinase (GCN2).Cost-effective and quality-assured.Formule :C18H12ClF2N5O3SDegré de pureté :99.08%Couleur et forme :SolidMasse moléculaire :451.83Ref: TM-T11375
1mg85,00€5mg170,00€10mg274,00€25mg547,00€50mg783,00€100mg1.074,00€1mL*10mM (DMSO)187,00€Sepantronium bromide
CAS :Sepantronium bromide (YM155) is a small-molecule proapoptotic agent with potential antineoplastic activity.Formule :C20H19BrN4O3Degré de pureté :99.68% - 99.82%Couleur et forme :SolidMasse moléculaire :443.26Mirdametinib
CAS :Mirdametinib (PD325901) is an MEK inhibitor (IC50=0.33 nM) with selective, non-ATP-competitive, and oral activity.Formule :C16H14F3IN2O4Degré de pureté :99.18% - 99.63%Couleur et forme :White PowderMasse moléculaire :482.19Ref: TM-T6189
1g898,00€5mg51,00€10mg74,00€25mg127,00€50mg175,00€100mg273,00€200mg406,00€500mg662,00€1mL*10mM (DMSO)55,00€Ligustilide
CAS :3-Butylidene-4,5-dihydrophthalide is an effective constituent extracted from Angelica sinensis.Formule :C12H14O2Degré de pureté :96.03% - 98.14%Couleur et forme :Yellow Brown PowderMasse moléculaire :190.24Nilotinib monohydrochloride monohydrate
CAS :Nilotinib monohydrochloride monohydrate (Nilotinib (monohydrochloride monohydrate)) is significantly potent BCR-ABL against, is a second generation tyrosineFormule :C28H22F3N7O·HCl·H2ODegré de pureté :99.93%Couleur et forme :SolidMasse moléculaire :583.99Vorinostat
CAS :Vorinostat (SAHA) is a pan-histone deacetylase (HDAC) inhibitor (IC50=10 nM) with inhibitory activity against HDAC1/2/3/6/7/11.Formule :C14H20N2O3Degré de pureté :99.47% - 99.65%Couleur et forme :White Crystalline SolidMasse moléculaire :264.32Isradipine
CAS :Isradipine (PN 200-110), a dihydropyridine, is an antihypertensive calcium channel blocker that dilates arteries and reduces resistance.Formule :C19H21N3O5Degré de pureté :99.65% - 99.84%Couleur et forme :Yellow SolidMasse moléculaire :371.39LRRK2-IN-1
CAS :LRRK2-IN-1 is an effective and selective LRRK2 inhibitor.Formule :C31H38N8O3Degré de pureté :98% - 98.82%Couleur et forme :SolidMasse moléculaire :570.69TG101209
CAS :TG101209 is a selective JAK2 inhibitor with IC50 of 6 nM.Formule :C26H35N7O2SDegré de pureté :100% - 99.36%Couleur et forme :SolidMasse moléculaire :509.67SR-18292
CAS :SR-18292 inhibits PGC-1α, enhances acetylation, lowers gluconeogenesis, and cuts hepatic glucose production.Formule :C23H30N2O2Degré de pureté :99% - 99.36%Couleur et forme :SolidMasse moléculaire :366.5Ref: TM-T4353
2mg40,00€5mg60,00€10mg87,00€25mg180,00€50mg283,00€100mg449,00€500mg938,00€1mL*10mM (DMSO)71,00€Mito-LND
CAS :Mito-LND (Mito-Loidamine) is an orally active and mitochondria-targeted inhibitor of oxidative phosphorylation.Formule :C43H45BrCl2N3OPDegré de pureté :97.25% - 98.34%Couleur et forme :SolidMasse moléculaire :801.62MRT68921 HCl
CAS :MRT68921 hydrochloride is a potent inhibitor of both ULK1 and ULK2 (IC50s: 2.9 and 1.1 nM, respectively).Formule :C25H34N6O·HClDegré de pureté :99.86% - 99.98%Couleur et forme :SolidMasse moléculaire :471.04GW786034B
CAS :Pazopanib HCl (Votrient) inhibits VEGFR1-3, PDGFR, FGFR, c-Kit, c-Fms with IC50 range 10-146 nM in cell-free assays.Formule :C21H23N7O2S·HClDegré de pureté :99.87%Couleur et forme :SolidMasse moléculaire :473.98Ref: TM-T6930
10mg52,00€25mg90,00€50mg96,00€100mg140,00€200mg229,00€500mg359,00€1mL*10mM (DMSO)52,00€Fexaramine
CAS :Fexaramine is a small molecule farnesoid X receptor (FXR) agonist with 100-fold increased affinity compared to natural compounds.Formule :C32H36N2O3Degré de pureté :98.87% - 99.61%Couleur et forme :SolidMasse moléculaire :496.64Danusertib
CAS :Danusertib (PHA-739358) is a small-molecule 3-aminopyrazole derivative with potential antineoplastic activity.Formule :C26H30N6O3Degré de pureté :97.88% - 98.44%Couleur et forme :White PowderMasse moléculaire :474.55Ref: TM-T2094
1mg59,00€2mg85,00€5mg116,00€10mg188,00€25mg365,00€50mg555,00€100mg795,00€500mg1.605,00€1mL*10mM (DMSO)120,00€UNBS5162
CAS :UNBS5162 (UNBS-5162) is a novel naphthalimide that decreases CXCL chemokine expression in experimental prostate cancers.Formule :C17H18N4O3Degré de pureté :98.37% - 99.97%Couleur et forme :SolidMasse moléculaire :326.35Ref: TM-T2477
1mg39,00€5mg81,00€10mg116,00€25mg215,00€50mg340,00€100mg540,00€200mg787,00€1mL*10mM (DMSO)89,00€PFK-015
CAS :PFK-015 (PFK15) is an effective inhibitor of PFKFB3 (IC50: 110 nM) and inhibits PFKFB3 activity in Y cells (IC50: 20 nM).Formule :C17H12N2ODegré de pureté :98.94% - 99.7%Couleur et forme :SolidMasse moléculaire :260.29Ref: TM-T2455
5mg57,00€10mg88,00€25mg159,00€50mg283,00€100mg419,00€200mg582,00€500mg928,00€1mL*10mM (DMSO)57,00€TPEN
CAS :TPEN (TPEDA) is a specific cell-permeable heavy metal chelator.Formule :C26H28N6Degré de pureté :98% - 99.72%Couleur et forme :White Crystalline PowderMasse moléculaire :424.54Gemcitabine elaidate
CAS :Gemcitabine elaidate (CP-4126), is a lipophilic, unsaturated fatty acid ester derivative of gemcitabine (dFdC), an antimetabolite deoxynucleoside analogue, withFormule :C27H43F2N3O5Couleur et forme :SolidMasse moléculaire :527.64FB49
FB49 is a selective Bcl-2-associated athanogene 3 (BAG3) inhibitor with a Ki of 45 μM.Formule :C17H18N2O6SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :378.4Vandetanib
CAS :Vandetanib (ZD6474) is a potent inhibitor of VEGFR2 (IC50: 40 nM). It also inhibits VEGFR3 and EGFR.Formule :C22H24BrFN4O2Degré de pureté :100% - 99.84%Couleur et forme :White SolidMasse moléculaire :475.35Ref: TM-T1656
10mg49,00€25mg69,00€50mg97,00€100mg170,00€200mg235,00€500mg379,00€1mL*10mM (DMSO)55,00€Irinotecan hydrochloride trihydrate
CAS :Irinotecan hydrochloride trihydrate (CPT-11 HCl Trihydrate) keeps DNA from unwinding by inhibiting topoisomerase 1.Formule :C33H45ClN4O9Degré de pureté :98.22% - 99.79%Couleur et forme :Pale Yellow To Yellow Crystalline PowderMasse moléculaire :677.18Sunitinib Malate
CAS :Sunitinib Malate (Sunitinib) is an indolinone-based tyrosine kinase inhibitor.Formule :C26H33FN4O7Degré de pureté :98% - 99.26%Couleur et forme :SolidMasse moléculaire :532.56Autophinib
CAS :Autophinib is a potent autophagy inhibitor with a novel chemotype with IC50 values of 90 and 40 nM for autophagy in starvation induced autophagy assay andFormule :C14H11ClN6O3Degré de pureté :99.25% - 99.41%Couleur et forme :SolidMasse moléculaire :346.73Doxazosin mesylate
CAS :Doxazosin mesylate (UK 33274 mesylate)(UK 33274) is a quinazoline-derivative. It is a selectively antagonizes postsynaptic α1-adrenergic receptors.Formule :C24H29N5O8SDegré de pureté :99.92%Couleur et forme :White To Off-White Crystalline PowderMasse moléculaire :547.58palovarotene
CAS :Palovarotene (Ro 3300074) is an agonist of nuclear retinoic acid receptor γ (RAR-γ).Formule :C27H30N2O2Degré de pureté :96.89% - 98.05%Couleur et forme :SolidMasse moléculaire :414.54Lucanthone
CAS :Lucanthone (Lucanthonum) is an inhibitor of Apurinic endonuclease-1 (APE-1).Formule :C20H24N2OSDegré de pureté :99.92%Couleur et forme :Yellow Crystals From Alcohol SolidMasse moléculaire :340.48Ref: TM-T4569
1mg56,00€2mg80,00€5mg126,00€10mg188,00€25mg400,00€50mg592,00€100mg837,00€1mL*10mM (DMSO)140,00€AZD-8055
CAS :AZD8055 is an ATP-competitive mTOR inhibitor (IC50: 0.8 nM in MDA-MB-468 cells). It is ~1,000-fold selective for mTOR over all PI3K isoforms.Formule :C25H31N5O4Degré de pureté :98% - 99.69%Couleur et forme :SolidMasse moléculaire :465.54Syringin
CAS :Syringin (eleutheroside-b) is a compound with antitumor, antiproliferative, immunomodulatory and platelet aggregation inhibiting effects.Formule :C17H24O9Degré de pureté :98.89% - 99.56%Couleur et forme :SolidMasse moléculaire :372.37CCT007093
CAS :CCT007093 is an effective PPM1D (WIP1) inhibitor (IC50: 8.4 μM).Formule :C15H12OS2Degré de pureté :98% - 99.75%Couleur et forme :SolidMasse moléculaire :272.39ML-SA1
CAS :ML-SA1 (Mucolipin synthetic agonist 1) is a selective TRPML agonist, inhibits DENV2 and ZIKV by promoting lysosomal acidification and protease activity.Formule :C22H22N2O3Degré de pureté :99.71%Couleur et forme :SolidMasse moléculaire :362.42Ref: TM-T23004
2mg37,00€5mg51,00€10mg81,00€25mg150,00€50mg244,00€100mg364,00€200mg550,00€1mL*10mM (DMSO)58,00€WYC-209
CAS :WYC-209 inhibits proliferation of malignant murine melanoma tumor-repopulating cells (TRCs, IC50: 0.19 uM). It targets the retinoic acid receptor (RAR).Formule :C20H20N2O3SDegré de pureté :99.77%Couleur et forme :SolidMasse moléculaire :368.45CZC-54252 hydrochloride
CAS :CZC-54252 hydrochloride: selective LRRK2 inhibitor; IC50 = 1.85/1.28 nM (wild-type/G2019S); neuroprotective; EC50 = 1 nM for G2019S injury.Formule :C22H26Cl2N6O4SDegré de pureté :98.21%Couleur et forme :SolidMasse moléculaire :541.45Ref: TM-T39202
5mg52,00€10mg75,00€25mg135,00€50mg215,00€100mg319,00€200mg449,00€1mL*10mM (DMSO)64,00€VER-155008
CAS :VER-155008 is a potent Hsp70 family inhibitor with IC50 of 0.5 μM, 2.6 μM, and 2.6 μM in cell-free assays for HSP70, HSC70, and GRP78, respectively.Formule :C25H23Cl2N7O4Degré de pureté :98.88% - 99.55%Couleur et forme :SolidMasse moléculaire :556.4Ref: TM-T7010
2mg47,00€5mg69,00€10mg93,00€25mg163,00€50mg283,00€100mg467,00€200mg653,00€1mL*10mM (DMSO)85,00€Rhein
CAS :Rhein (NSC 38629) is an anthraquinone compound extracted from Polygonaceae Rheum Officinale with anti-inflammation and antitumor activities.Formule :C15H8O6Degré de pureté :99.04%Couleur et forme :Physical Description Yellow Needles (From Methanol) Or Yellow-Brown Powder (Ntp 1992)Masse moléculaire :284.22Rotenone
CAS :Rotenone, a plant-derived insecticide, inhibits mitochondrial electron transport, found in Leguminosae.Formule :C23H22O6Degré de pureté :89.58% - 99.88%Couleur et forme :Less To Brownish Crystals Or A White To Brownish-White Crystalline Powder Has Neither Odor Nor Taste (Ntp 1992)Masse moléculaire :394.42Tacrolimus
CAS :Tacrolimus (Fujimycin) can bind FKBP12 to form a high-affinity complex (Ki: 0.2 nM) which inhibits the activity of the calcium/calmodulin-dependent proteinFormule :C44H69NO12Degré de pureté :98% - 99.94%Couleur et forme :White Or Off-White Crystalline PowderMasse moléculaire :804.02Ref: TM-T2144
10mg46,00€25mg60,00€50mg74,00€100mg104,00€200mg147,00€500mg244,00€1mL*10mM (DMSO)50,00€Lapatinib Ditosylate
CAS :Lapatinib Ditosylate (Tykerb ditosylate) is an effective EGFR and ErbB2 inhibitor (IC50: 10.8/9.2 nM for EGFR/ErbB2).Formule :C29H26ClFN4O4S·2C7H8O3SDegré de pureté :99.41%Couleur et forme :Yellow SolidMasse moléculaire :925.46CZC-54252
CAS :CZC-54252 is a potent inhibitor of LRRK2.Formule :C22H25ClN6O4SDegré de pureté :99.39%Couleur et forme :SolidMasse moléculaire :504.99Fenofibrate
CAS :Fenofibrate (Lipanthyl) is a PPARα agonist. Fenofibrate inhibits cytochrome P450 isoforms. Fenofibrate exhibits antihyperlipidemic activity. Cost-effective and quality-assured.Formule :C20H21ClO4Degré de pureté :99.13% - 99.95%Couleur et forme :Crystals From Isopropanol SolidMasse moléculaire :360.83Amiodarone hydrochloride
CAS :Amiodarone HCl: Antianginal, class III antiarrhythmic. Lengthens heart muscle action, slows heart rate, reduces vascular resistance.Formule :C25H29I2NO3·HClDegré de pureté :99.49% - ≥95%Couleur et forme :White To Cream Crystalline PowderMasse moléculaire :681.78STO-609
CAS :STO-609 inhibits CaM-KKα/KKβ (Ki: 80/15 ng/mL), is specific, cell-permeable, and targets Ca2+/calmodulin-dependent protein kinase kinase.Formule :C19H10N2O3Degré de pureté :97.14% - 98.95%Couleur et forme :SolidMasse moléculaire :314.29Ref: TM-T3546
1mg42,00€5mg88,00€10mg127,00€25mg264,00€50mg423,00€100mg655,00€500mg1.359,00€1mL*10mM (DMSO)113,00€Isoniazid
CAS :Isoniazid (Isonicotinic hydrazide) is an antibacterial agent used primarily as a tuberculostatic.Formule :C6H7N3ODegré de pureté :98.49% - 99.21%Couleur et forme :Colorless Or White Crystals Or A White Crystalline Powder Slightly Sweet At First And Then Bitter Ph (1% Aqueous Solution) 5 5-6 5 Ph (5% Aqueous Solution) 6-Masse moléculaire :137.14GLPG1837
CAS :GLPG1837 (ABBV-974) is an effective CFTR potentiator, with EC50s of 3 nM and 339 nM for F508del and G551D CFTR, respectively.Formule :C16H20N4O3SDegré de pureté :98.75% - 99.73%Couleur et forme :SolidMasse moléculaire :348.42Ref: TM-T7083
1mg35,00€5mg80,00€10mg120,00€25mg188,00€50mg354,00€100mg537,00€200mg750,00€1mL*10mM (DMSO)88,00€Isosorbide Mononitrate
CAS :Isosorbide Mononitrate (Corangin) is a Nitrate Vasodilator, dilating the blood vessels so as to reduce the blood pressure.Formule :C6H9NO6Degré de pureté :98.16%Couleur et forme :Isosorbide-5-Mononitrate Is A Crystalline Solid It Is Very Flammable And May Be Toxic By IngestionMasse moléculaire :191.14Sulfabenzamide
CAS :Sulfabenzamide (N-Sulfanilylbenzamide) is a sulfonamide antibacterial agent used alone or with sulfathiazole and sulfacetamide as a topical, intravaginalFormule :C13H12N2O3SDegré de pureté :99.82%Couleur et forme :White To Off-White SolidMasse moléculaire :276.31UBCS039
CAS :UBCS039 is the first synthetic Sirt6 activator(EC50 : 38 μM)Formule :C16H13N3Degré de pureté :99.75%Couleur et forme :SolidMasse moléculaire :247.29Ref: TM-T7679
1mg40,00€5mg81,00€10mg116,00€25mg226,00€50mg324,00€100mg452,00€200mg632,00€1mL*10mM (DMSO)100,00€U0126
CAS :U0126, an effective and selective non-competitive inhibitor of MAP kinase, inhibits MEK-1 and MEK-2 with IC50 values of 0.07 and 0.06 μM respectively.Formule :C18H16N6S2Degré de pureté :98%Couleur et forme :White SolidMasse moléculaire :380.49AZD-3463
CAS :AZD-3463 (ALK/IGF1R inhibitor) , an orally bioavailable ALK inhibitor (Ki: 0.75 nM), can inhibit IGF1R with equivalent potency.Formule :C24H25ClN6ODegré de pureté :99.13%Couleur et forme :SolidMasse moléculaire :448.95Vacuolin-1
CAS :Vacuolin-1 is a cell-permeable inhibitor of Ca2+ dependent fusion of lysosomes to the cell membrane.Formule :C26H24IN7ODegré de pureté :97.20% - 98.45%Couleur et forme :SolidMasse moléculaire :577.42Nictide
CAS :Nictide, a peptide substrate for LRRK2 (leucine-rich repeat protein kinase-2), undergoes phosphorylation by the activated form of LRRK2[G2019S], exhibiting a Km value of 10 μM.Formule :C123H193N45O28Couleur et forme :SolidMasse moléculaire :2750.13RAF265
CAS :RAF265 (CHIR-265) inhibits C-Raf/B-Raf/V600E (IC50: 3-60 nM), blocks VEGFR2 (EC50: 30 nM), in Phase 2 trials.Formule :C24H16F6N6ODegré de pureté :99.56%Couleur et forme :SolidMasse moléculaire :518.41Ref: TM-T6296
1mg47,00€2mg63,00€5mg87,00€10mg147,00€25mg266,00€50mg435,00€100mg640,00€1mL*10mM (DMSO)99,00€Wortmannin
CAS :Wortmannin (SL-2052) is a PI3K inhibitor (IC50=3 nM) that is covalent and irreversible.Formule :C23H24O8Degré de pureté :95.84% - 99.76%Couleur et forme :White SolidMasse moléculaire :428.43Ketanserin
CAS :Ketanserin: quinazoline derivative, 5-HT2 receptor antagonist, may lower blood pressure and inhibit blood clots.Formule :C22H22FN3O3Degré de pureté :99.19% - 99.73%Couleur et forme :SolidMasse moléculaire :395.43Mifepristone
CAS :Mifepristone (C-1073) is a Progestin Antagonist. The mechanism of action of mifepristone is as a Progestational Hormone Receptor Antagonist.Formule :C29H35NO2Degré de pureté :98.9% - ≥95%Couleur et forme :Pale Yellow SolidMasse moléculaire :429.59Cisplatin
CAS :Cisplatin (CDDP) is a DNA cross-linking agent.Formule :Cl2H6N2PtDegré de pureté :97.13% - 99.63%Couleur et forme :Orange-Yellow To Deep Yellow Solid Or PowderMasse moléculaire :300.04Berberine
CAS :1.Formule :C20H18NO4Degré de pureté :95.71% - 99.38%Couleur et forme :SolidMasse moléculaire :336.36Bicalutamide
CAS :Bicalutamide (ICI-176334), a synthetic, nonsteroidal antiandrogen, competitively binds to cytosolic androgen receptors in target tissues, thereby inhibiting theFormule :C18H14F4N2O4SDegré de pureté :98% - 99.87%Couleur et forme :Off-White Crystalline SolidMasse moléculaire :430.37Carvedilol phosphate hemihydrate
CAS :Carvedilol phosphate hemihydrate (BM 14190 phosphate hemihydrate) is the phosphate salt form of carvedilol, a racemic mixture and adrenergic blocking agent.Formule :C24H26N2O4·5H2O·H3O4PDegré de pureté :99.24%Couleur et forme :SolidMasse moléculaire :513.49Crustecdysone
CAS :Crustecdysone (Hydroxyecdysone) is a steroid hormone that regulates the processes of molting or ecdysis in insects.Formule :C27H44O7Degré de pureté :96.31% - 99.06%Couleur et forme :Canary Yellow Fine PowderMasse moléculaire :480.63SP600125
CAS :SP600125 (JNK Inhibitor II) is a JNK inhibitor that inhibits JNK1, JNK2, and JNK3 (IC50=40/40/90 nM) with oral potency, reversibility, and ATP-competitiveFormule :C14H8N2ODegré de pureté :97.63% - 99.58%Couleur et forme :SolidMasse moléculaire :220.2320-DEOXYINGENOL
CAS :20-DEOXYINGENOL is a natual product.Formule :C20H28O4Degré de pureté :99.98% - ≥95%Couleur et forme :SolidMasse moléculaire :332.43Ulipristal acetate
CAS :Ulipristal acetate (CDB-2914) is an oral selective progesterone modulator used for emergency contraception and suppressing uterine growths.Formule :C30H37NO4Degré de pureté :98.83% - 99.94%Couleur et forme :SolidMasse moléculaire :475.62SB 216763
CAS :SB 216763 (SB216763) is an effective and specific GSK-3α/β inhibitor (IC50: 34.3 nM).Formule :C19H12Cl2N2O2Degré de pureté :99.13% - 99.61%Couleur et forme :SolidMasse moléculaire :371.22Ref: TM-T3077
2mg39,00€5mg52,00€10mg79,00€25mg131,00€50mg197,00€100mg334,00€500mg803,00€1mL*10mM (DMSO)52,00€SHP2-IN-35
SHP2-IN-35 (Compound 3f) functions as an inhibitor of SHP2. It exhibits antiproliferative activity in cancer cell lines RKO, SW480, and CT26, with IC50 values of 5.72 μM, 3.71 μM, and 1.42 μM, respectively. SHP2-IN-35 inhibits the PI3K-Akt signaling pathway, regulates the expression of cell cycle-related genes, and induces mitochondrial autophagy (autophagy). Within the tumor microenvironment (TME), SHP2-IN-35 suppresses the expression of certain cytokines and chemokines, thereby modulating tumor progression.Formule :C34H32FeO6Couleur et forme :SolidMasse moléculaire :592.46Norepinephrine
CAS :Norepinephrine (Levophed) can stimulate apoptosis in adult rat ventricular myocytes by activation of the β-adrenergic pathway.Formule :C8H11NO3Degré de pureté :98.56% - 99.84%Couleur et forme :Colorless Micr°Crystals SolidMasse moléculaire :169.18PAC-1
CAS :PAC-1 (Procaspase activating compound 1) has been used in trials studying the treatment of Lymphoma, Melanoma, Solid Tumors, Breast Cancer and Thoracic Cancers.Formule :C23H28N4O2Degré de pureté :96.78% - 99.77%Couleur et forme :SolidMasse moléculaire :392.49Momelotinib
CAS :Momelotinib (LM-1149), an oral JAK1/2 inhibitor with IC50s 11/18 nM, blocks ATP binding, disrupting JAK-STAT pathway and reducing tumor growth.Formule :C23H22N6O2Degré de pureté :97.47% - 99.56%Couleur et forme :SolidMasse moléculaire :414.46Ref: TM-T1849
1mg38,00€2mg49,00€5mg81,00€10mg95,00€25mg166,00€50mg259,00€100mg406,00€200mg625,00€1mL*10mM (DMSO)88,00€AGN 193109
CAS :AGN 193109, a retinoid analog, is a potent and specific antagonist of RARs (Kds: 2 nM, 2 nM, and 3 nM for RARα, RARβ, and RARγ).Formule :C28H24O2Degré de pureté :98.81% - 99.89%Couleur et forme :SolidMasse moléculaire :392.49Ginsenoside Rb1
CAS :Ginsenoside Rb1 (Gypenoside Ⅲ) is part of a class of steroid glycosides; may have properties that inhibit or prevent the growth of tumors.Formule :C54H92O23Degré de pureté :99.12% - 99.76%Couleur et forme :SolidMasse moléculaire :1109.29Rasagiline Mesylate
CAS :Rasagiline Mesylate (AGN1135) is a novel MAO-B inhibitor, which can treat idiopathic Parkinson's disease.Formule :C13H17NO3SDegré de pureté :99.33%Couleur et forme :White PowderMasse moléculaire :267.34Cucurbitacin E
CAS :Cucurbitacin E, from Cucumic melo, inhibits cyclin B1/CDC2, and has neuroprotective, anti-proliferative, anti-cancer, and pain relief properties.Formule :C32H44O8Degré de pureté :98.88% - 99.19%Couleur et forme :SolidMasse moléculaire :556.69Ref: TM-T5S1467
1mg59,00€5mg115,00€10mg177,00€25mg300,00€50mg445,00€100mg643,00€1mL*10mM (DMSO)140,00€Nutlin-3a
CAS :Nutlin-3a is the active enantiomer of Nutlin-3, an MDM2 antagonist that inhibits MDM2-p53 interaction. Nutlin-3a has antitumor activity. Cost-effective and quality-assured.Formule :C30H30Cl2N4O4Degré de pureté :95.62% - 99.71%Couleur et forme :SolidMasse moléculaire :581.49Ref: TM-T6023
1mg49,00€2mg70,00€5mg96,00€10mg164,00€25mg268,00€50mg398,00€100mg587,00€1mL*10mM (DMSO)135,00€Valinomycin
CAS :Valinomycin (NSC-122023) is a cyclic depsipeptide antibiotic and a potassium-specific ionophore.Valinomycin induces PINK1 activation and promotes ParkinFormule :C54H90N6O18Degré de pureté :100%Couleur et forme :White SolidMasse moléculaire :1111.32Sophocarpine monohydrate
CAS :Sophocarpine monohydrate, a major ingredient of Sophora alopecuroides, has a wide range of pharmacological effects.Formule :C15H22N2ODegré de pureté :99.55%Couleur et forme :SolidMasse moléculaire :246.35AM580
CAS :AM580 (CD336) is a retinoic acid receptor agonist that is selective for RARα( IC50 : 8 nM )Formule :C22H25NO3Degré de pureté :98% - 99.89%Couleur et forme :SolidMasse moléculaire :351.44Ref: TM-T5854
2mg39,00€5mg57,00€10mg87,00€25mg164,00€50mg316,00€100mg469,00€500mg1.064,00€1mL*10mM (DMSO)64,00€LYN-1604
CAS :LYN-1604 is a novel activator of ULK1, inducing cell death involved in ATF3, RAD21, and caspase3, accompanied by autophagy and apoptosis.Formule :C33H43Cl2N3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :584.62Stavudine
CAS :Stavudine (BMY-27857), a nucleoside reverse transcriptase inhibitor analog of thymidine, has activity against HIV.Formule :C10H12N2O4Degré de pureté :100% - 99.74%Couleur et forme :White PowderMasse moléculaire :224.213-Methyladenine
CAS :3-Methyladenine (3-MA) is a PI3K inhibitor that selectively inhibits class IB PI3Kγ (IC50=60 μM) and class III VPS34 (IC50=25 μM).Formule :C6H7N5Degré de pureté :98.02% - 99.51%Couleur et forme :SolidMasse moléculaire :149.15Typhaneoside
CAS :Typhaneoside (Aervitrin) is a flavonoid glycoside plant extract with potential ability to treat primary dysmenorrhea through the Shaofu Zhuyu decoction.Formule :C34H42O20Degré de pureté :98.92% - 99.95%Couleur et forme :SolidMasse moléculaire :770.69Glycycoumarin
CAS :Glycycoumarin is an estrogen agonist, it shows moderate inhibitory effects against CYP1A2 and CYP2B6.Formule :C21H20O6Degré de pureté :97.64% - 99.78%Couleur et forme :SolidMasse moléculaire :368.38Ref: TM-TN1702
1mg42,00€5mg81,00€10mg122,00€25mg235,00€50mg348,00€100mg515,00€200mg743,00€1mL*10mM (DMSO)89,00€Telaglenastat
CAS :Telaglenastat (CB 839) (IC50 of 24 nM), an effective, specific, and oral inhibitor, which is bioavailable glutaminase, for recombinant human GAC.Formule :C26H24F3N7O3SDegré de pureté :100% - 99.89%Couleur et forme :SolidMasse moléculaire :571.57Ref: TM-T6797
1g1.130,00€2mg38,00€5mg51,00€10mg79,00€25mg126,00€50mg210,00€100mg350,00€500mg825,00€1mL*10mM (DMSO)65,00€Dantrolene sodium hemiheptahydrate
CAS :Dantrolene depresses excitation-contraction coupling in skeletal muscle by binding to the ryanodine receptor 1 and decreasing intracellular calciumFormule :C14H9N4NaO5·5H2ODegré de pureté :99.72%Couleur et forme :Orange PowderMasse moléculaire :399.29Fangchinoline
CAS :Fangchinoline (Tetrandrine B) is extracted from Stephania tetrandra S. Moore.Formule :C37H40N2O6Degré de pureté :98.81% - 99.86%Couleur et forme :SolidMasse moléculaire :608.72Bexarotene
CAS :Bexarotene (LGD1069) is a retinoid analogue that is used to treat the skin manifestations of cutaneous T cell lymphoma (CTCL).Formule :C24H28O2Degré de pureté :99% - 99.65%Couleur et forme :White SolidMasse moléculaire :348.48Vemurafenib
CAS :Vemurafenib (RG7204) is a B-RAF inhibitor that inhibits RAFV600E and c-RAF-1 (IC50=31/48 nM) selectively and potently.Formule :C23H18ClF2N3O3SDegré de pureté :98% - 99.65%Couleur et forme :SolidMasse moléculaire :489.92FKBP51F67V-selective antagonist Ligand2
CAS :FKBP51F67V-selective antagonist Ligand2 (example 3-3), a potent ligand, selectively binds to the FKBP51 F67V variant, with no affinity for wild-type FKBP51 orFormule :C43H56N2O10Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :760.91Tarenflurbil
CAS :Tarenflurbil, the R-enantiomer of flurbiprofen, lacks COX inhibition and was tested for Alzheimer's treatment.Formule :C15H13FO2Degré de pureté :100% - 98%Couleur et forme :SolidMasse moléculaire :244.26NVP-AEW541
CAS :NVP-AEW541 (AEW541), a potent inhibitor of IGF-1R(IC50=150 nM) and InsR(IC50=140 nM), exhibits excellent efficiency and specificity for IGF-1R in a cell-basedFormule :C27H29N5ODegré de pureté :96.03% - 99.55%Couleur et forme :SolidMasse moléculaire :439.55PHA-665752
CAS :PHA-665752 is an effective, specific and ATP-competitive c-Met inhibitor (IC50: 9 nM), >50-fold selectivity for c-Met than STKs or RTKs.Formule :C32H34Cl2N4O4SDegré de pureté :97.01% - 99.35%Couleur et forme :SolidMasse moléculaire :641.61Oleanolic Acid
CAS :Oleanolic Acid (Caryophyllin) is a natural compound with anti-tumor activities, which are widely distributed in plants.Formule :C30H48O3Degré de pureté :98.4% - 98.51%Couleur et forme :SolidMasse moléculaire :456.7GW406108X
CAS :GW406108X is a Kif15 and ULK1 inhibitor; IC50: 0.82 µM (ATPase), pIC50: 6.37; blocks autophagy.Formule :C20H11Cl2NO4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :400.21AG490
CAS :AG490 inhibits EGFR (0.1 μM IC50), 135x > selective than ErbB2, blocks JAK2, spares Lyn, Lck, Syk, Btk, Src.Formule :C17H14N2O3Degré de pureté :98.6% - 99.39%Couleur et forme :Yellow SolidMasse moléculaire :294.3Brefeldin A
CAS :Brefeldin A (Cyanein) belongs to the class of macrolide antibiotics and is an ATPase inhibitor (IC50=0.2 μM).Formule :C16H24O4Degré de pureté :96.45% - 99.89%Couleur et forme :White SolidMasse moléculaire :280.36Tolbutamide
CAS :Tolbutamide (HLS 831) is a sulphonylurea hypoglycemic agent with actions and uses similar to those of CHLORPROPAMIDE.Formule :C12H18N2O3SDegré de pureté :99.80% - 99.93%Couleur et forme :White Crystalline PowderMasse moléculaire :270.35Pyrazinamide
CAS :Pyrazinamide (Pyrazinecarboxamide), an antimycobacterial, is utilized therapeutically as an antitubercular agent, which is a synthetic pyrazinoic acid amideFormule :C5H5N3ODegré de pureté :99.71% - 99.81%Couleur et forme :Crystals Physical Description White Powder Sublimes From 318°F (Ntp 1992)Masse moléculaire :123.11Elaiophylin
CAS :Elaiophylin exhibits anti-Plasmodium falciparum and anti-Trypanosoma brucei activity; IC50: 0.36 μM & 0.45 μM, respectively.Formule :C54H88O18Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1025.27BMS-582949 hydrochloride
CAS :The BMS-582949 hydrochloride (BMS-582949 HCl) is a highly specific p38α MAPK inhibitor (IC50: 13 nM).Formule :C22H27ClN6O2Degré de pureté :97.57% - 98.75%Couleur et forme :SolidMasse moléculaire :442.95Ref: TM-T3462
1mg35,00€5mg71,00€10mg101,00€25mg170,00€50mg264,00€100mg393,00€200mg552,00€1mL*10mM (DMSO)78,00€Sanguinarine chloride
CAS :Sanguinarine chloride (Pseudochelerythrine chloride), a benzophenanthridine alkaloid, stimulates apoptosis by activating the production of reactive oxygenFormule :C20H14ClNO4Degré de pureté :98% - 99.41%Couleur et forme :SolidMasse moléculaire :367.78Obatoclax Mesylate
CAS :Obatoclax Mesylate (GX15-070) is a Bcl-2 antagonist (Ki: 0.22 μM) and can induce apoptosis with up-regulation of Bim, induced cytochrome c release, andFormule :C20H19N3O·CH4O3SDegré de pureté :99.67% - 99.88%Couleur et forme :SolidMasse moléculaire :413.49Rosiglitazone hydrochloride
CAS :Rosiglitazone hydrochloride (BRL-49653 HCl) is a blood glucose-lowering drugs, stimulating insulin secretion by binding to the PPAR receptors in fat cells.Formule :C18H19N3O3S·HClDegré de pureté :99.63% - 99.79%Couleur et forme :SolidMasse moléculaire :393.89Fludrocortisone acetate
CAS :Fludrocortisone acetate (9α-Fludrocortisone acetate) , a glucocorticoid-receptor agonist, binds to cytoplasmic receptors, translocates to the nucleus, andFormule :C23H31FO6Degré de pureté :96.92% - 98.03%Couleur et forme :Crystalline SolidMasse moléculaire :422.49(-)-Epicatechin gallate
CAS :(-)-Epicatechin gallate, a catechin isomer and strong antioxidant, affects membrane proteins and alters gA channel function in bilayers.Formule :C22H18O10Degré de pureté :96.65% - 99.72%Couleur et forme :SolidMasse moléculaire :442.37ATG12-IN-1
CAS :ATG12-IN-1 (compound 4) acts as an autophagy inhibitor targeting the ATG12-ATG3 protein-protein interaction (IC50= 9 μM), suitable for research in cancer studies.Formule :C23H15ClN4O2Couleur et forme :SolidMasse moléculaire :414.84BPO-27 racemate
CAS :BPO-27 racemate (BPO-27 (racemate)) is an effective CFTR inhibitor with IC50 of 8 nM.Formule :C26H18BrN3O6Degré de pureté :98.19%Couleur et forme :SolidMasse moléculaire :548.34Ref: TM-T10591
1mg47,00€5mg117,00€10mg170,00€25mg280,00€50mg409,00€100mg565,00€200mg758,00€1mL*10mM (DMSO)135,00€Quercetin
CAS :Quercetin (Sophoretin) is a natural flavonoid and is an agonist of SIRT1.Formule :C15H10O7Degré de pureté :96.29% - 98.05%Couleur et forme :Sensitive To Exposure To Air And Light Insoluble In Water Alcoholic Solutions Taste Very Bitter (Ntp 1992)Masse moléculaire :302.24Cediranib
CAS :Cediranib (AZD2171) is a potent KDR tyrosine kinase inhibitor (IC50 < 1nM), also targets Flt1/4, PDGFRβ, c-Kit, and more selective for VEGFR.Formule :C25H27FN4O3Degré de pureté :97.21% - 99.94%Couleur et forme :SolidMasse moléculaire :450.51Ref: TM-T2500
2mg42,00€5mg63,00€10mg92,00€25mg136,00€50mg177,00€100mg254,00€200mg462,00€500mg742,00€1mL*10mM (DMSO)69,00€Ursolic acid
CAS :Ursolic acid (Prunol) is a natural pentacyclic triterpene carboxylic acid. Ursolic acid has anti-tumor and anti-inflammatory effects. Cost-effective and quality-assured.Formule :C30H48O3Degré de pureté :99.66% - 99.79%Couleur et forme :Platelets From Alcohol SolidMasse moléculaire :456.7LY294002
CAS :LY294002 (SF 1101) is a broad-spectrum inhibitor of PI3K, inhibiting PI3Kα, PI3Kδ, and PI3Kβ (IC50=0.5/0.57/0.97 μM).Formule :C19H17NO3Degré de pureté :98% - 99.96%Couleur et forme :Pale Yellow SolidMasse moléculaire :307.34Nobiletin
CAS :Nobiletin: a citrus-derived flavone with anti-inflammatory and anti-cancer properties; water-insoluble, very weak acid.Formule :C21H22O8Degré de pureté :98.78% - 99.76%Couleur et forme :SolidMasse moléculaire :402.39Ref: TM-T2834
5mg57,00€10mg88,00€25mg124,00€50mg168,00€100mg265,00€200mg393,00€500mg653,00€1mL*10mM (DMSO)59,00€Sinomenine
CAS :Sinomenine (Kukoline) is a pure alkaloid isolated from the Sinomenium acutum, is utilized in the treatment of rheumatism and arthritis.Formule :C19H23NO4Degré de pureté :99.02% - 99.89%Couleur et forme :White PowderMasse moléculaire :329.39Sulfosuccinimidyl oleate
CAS :Sulfosuccinimidyl oleate (Sulfo-N-succinimidyl oleate) (Sulfo-N-succinimidyl oleate) is a long chain fatty acid that inhibits fatty acid transport into cells.Formule :C22H37NO7SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :459.6Tubastatin A
CAS :Tubastatin A: Selective HDAC6 inhibitor, IC50 of 15 nM, 1000x less effective on other isozymes except HDAC8.Formule :C20H21N3O2Degré de pureté :97.22% - 99.51%Couleur et forme :SolidMasse moléculaire :335.4Ref: TM-T1966
10mg48,00€25mg64,00€50mg79,00€100mg111,00€200mg169,00€500mg274,00€1mL*10mM (DMSO)47,00€N-Benzylpalmitamide
CAS :N-Benzylpalmitamide (Macamide 1) inhibits fatty acid amide hydrolase (FAAH) in a time-dependent manner and could potentially offer a good alternative for theFormule :C23H39NODegré de pureté :97.08% - 99.77%Couleur et forme :SolidMasse moléculaire :345.56LG-100064
CAS :LG-100064 is an agonist of retinoid-X-receptor (RXR)(EC50s of 330 nM, 200 nM, and 260 nM for RXRα, RXRβ and RXRγ)Formule :C23H26O3Degré de pureté :98.65%Couleur et forme :SolidMasse moléculaire :350.45Ref: TM-T11844
2mg47,00€5mg70,00€10mg97,00€25mg167,00€50mg249,00€100mg369,00€200mg545,00€1mL*10mM (DMSO)77,00€Icaritin
CAS :Icaritin (Anhydroicaritin) has hormone regulation activity and cardiovascular function improvement activity.Formule :C21H20O6Degré de pureté :97.69% - 98.96%Couleur et forme :SolidMasse moléculaire :368.38EAD1
CAS :EAD1 is a useful organic compound for research related to life sciences. The catalog number is T35329 and the CAS number is 1644388-26-0.Formule :C24H27Cl2N7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :484.42R1487 Hydrochloride
CAS :R1487 Hydrochloride (R1487 (Hydrochloride)) is an orally bioavailable and highly selective inhibitors of p38α.Formule :C19H19ClF2N4O3Degré de pureté :99.42%Couleur et forme :SolidMasse moléculaire :424.834E2RCat
CAS :4E2RCat is an inhibitor of eIF4E-eIF4G interaction (IC50 = 13.5 μM) and is capable of blocking coronavirus replication as monitored by viral protein expressionFormule :C22H14ClNO4S2Degré de pureté :96.48%Couleur et forme :SolidMasse moléculaire :455.93Onjisaponin B
CAS :Onjisaponin B induces autophagy via the AMPK-mTOR signaling pathway, increases the NGF level and accelerates both the removal of mutant huntingtin and A53T α±-Formule :C75H112O35Degré de pureté :99.20% - 99.88%Couleur et forme :SolidMasse moléculaire :1573.67Rilmenidine Phosphate
CAS :Rilmenidine Phosphate is a selective I(1) imidazoline receptor agonist, used to treat hypertension.Formule :C10H19N2O5PDegré de pureté :99.87% - ≥95%Couleur et forme :SolidMasse moléculaire :278.24Ref: TM-T6641
1mg40,00€5mg88,00€10mg137,00€25mg264,00€50mg418,00€100mg627,00€500mg1.301,00€1mL*10mM (DMSO)87,00€
