Autophagie
Les inhibiteurs de l'autophagie ciblent le processus cellulaire de l'autophagie, qui implique la dégradation et le recyclage des composants cellulaires via les lysosomes. L'autophagie est un mécanisme crucial pour maintenir l'homéostasie cellulaire, mais sa dérégulation est impliquée dans diverses maladies, y compris le cancer, les maladies neurodégénératives et les infections. Les inhibiteurs de l'autophagie peuvent bloquer ce processus, ce qui en fait des outils précieux pour étudier le rôle de l'autophagie dans les maladies et développer des stratégies thérapeutiques. Chez CymitQuimica, nous proposons des inhibiteurs de l'autophagie pour soutenir vos recherches en biologie cellulaire, oncologie et maladies neurodégénératives.
Produits appartenant à la catégorie "Autophagie"
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CAS :IST5-002 (N6-Benzyladenosine-5'-phosphate) is a Stat5a/b inhibitor with anticancer activity and is used in cancer research.Formule :C16H14BrN5Degré de pureté :100%Couleur et forme :SolidMasse moléculaire :356.22Apigenin
CAS :Apigenin (NSC 83244) is an aromatic oil extracted from the flowers or leaves of the daisy-like plants.Formule :C15H10O5Degré de pureté :97.95% - 99.66%Couleur et forme :Yellow Needles From Aqueous Pyridine SolidMasse moléculaire :270.24Divalproex Sodium
CAS :Divalproex Sodium (Valproate semisodium) binds to and inhibits gamma-aminobutyric acid (GABA) transaminase and its anticonvulsant activity may be exerted byFormule :C8H16O2·C8H15O2·NaDegré de pureté :99.84%Couleur et forme :A White Powder With A Characteristic OdorMasse moléculaire :310.41Ref: TM-T6474
10mg39,00€25mg55,00€50mg79,00€100mg116,00€200mg188,00€500mg335,00€1mL*10mM (DMSO)55,00€Torin 2
CAS :Torin 2: mTOR inhibitor, IC50=0.25 nM, 800x more selective than PI3K, with EC50=28/35/118 nM for ATM/ATR/DNA-PK.Formule :C24H15F3N4ODegré de pureté :98.31% - 99.32%Couleur et forme :SolidMasse moléculaire :432.4Ginkgetin
CAS :Ginkgetin: antiviral, antifungal, anti-inflammatory; COX-2 reducer; STAT3 inhibitor; pro-apoptotic in cancer; neuroprotective in Parkinson's.Formule :C32H22O10Degré de pureté :98.91% - 99.94%Couleur et forme :SolidMasse moléculaire :566.51Ref: TM-T4S2126
1mg58,00€5mg118,00€10mg172,00€25mg278,00€50mg411,00€100mg607,00€200mg847,00€1mL*10mM (DMSO)153,00€Maprotiline hydrochloride
CAS :Maprotiline hydrochloride (Psymion) is a tetracyclic antidepressant akin to tricyclics with similar side effects.Formule :C20H24ClNDegré de pureté :99.68% - 99.84%Couleur et forme :White PowderMasse moléculaire :313.864Hydroxyurea
CAS :Hydroxyurea (Hydroxycarbamide), an antineoplastic agent, inhibits DNA synthesis through the inhibition of ribonucleoside diphosphate reductase.Formule :CH4N2O2Degré de pureté :99.85% - 99.92%Couleur et forme :SolidMasse moléculaire :76.05Carbamazepine
CAS :Carbamazepine: a tricyclic with anticonvulsant and analgesic effects, treats trigeminal neuralgia.Formule :C15H12N2ODegré de pureté :99.79% - 99.88%Couleur et forme :SolidMasse moléculaire :236.27Saquinavir mesylate
CAS :Saquinavir mesylate (Ro 31-8959/003) is an Inhibitor of HIV Proteaseused in antiretroviral therapyFormule :C39H54N6O8SDegré de pureté :99.19%Couleur et forme :White Or Pale Yellow PowderMasse moléculaire :766.9Imatinib
CAS :Imatinib (STI571) is a multi-targeted receptor tyrosine kinase inhibitor that selectively inhibits the kinase activities of BCR/ABL, v-Abl, PDGFR, and c-kitFormule :C29H31N7ODegré de pureté :100% - 99.94%Couleur et forme :Off White PowderMasse moléculaire :493.6Polyphyllin I
CAS :Polyphyllin D induces apoptosis via the mitochondrial apoptotic pathway as evidenced by decreased Bcl-2 expression levels, disruption of MMP and increased Bax,Formule :C44H70O16Degré de pureté :98% - 99.5%Couleur et forme :SolidMasse moléculaire :855.02Troglitazone
CAS :Troglitazone (Romglizone) is a PPARγ agonist with anti-inflammatory and anti-tumor activity.Formule :C24H27NO5SDegré de pureté :98% - 99.62%Couleur et forme :Yellow SolidMasse moléculaire :441.54Ref: TM-T3170
2mg42,00€5mg62,00€10mg88,00€25mg172,00€50mg305,00€100mg558,00€500mg1.169,00€1mL*10mM (DMSO)85,00€Liensinine diperchlorate
CAS :Liensinine Diperchlorate is an isoquinoline alkaloid extracted from the embryonic seeds of the sacred lotus.Formule :C37H44Cl2N2O14Degré de pureté :99.8% - ≥95%Couleur et forme :SolidMasse moléculaire :811.67Tripterin
CAS :Tripterin (Celastrol) is an proteasome inhibitor for the chymotrypsin-like activity of a purified 20S proteasome with antioxidant and anti-inflammatory effects.Formule :C29H38O4Degré de pureté :98.56% - 99.8%Couleur et forme :Red Crystalline PowderMasse moléculaire :450.61LYN-1604 dihydrochloride
CAS :LYN-1604 is a novel ULK1 activator.It inducing cell death involved in ATF3, RAD21, and caspase3, accompanied by autophagy and apoptosis.Formule :C33H45Cl4N3O2Degré de pureté :98.95% - 99.80%Couleur et forme :SolidMasse moléculaire :657.54Ref: TM-T8808L
1mg35,00€5mg78,00€10mg117,00€25mg212,00€50mg316,00€100mg447,00€200mg628,00€1mL*10mM (DMSO)101,00€BIA 10-2474
CAS :BIA 10-2474 is a long-acting reversible inhibitor of FAAH that increases levels of the neurotransmitter anandamide in the nervous system.Formule :C16H20N4O2Degré de pureté :99.27%Couleur et forme :SolidMasse moléculaire :300.36Xylitol
CAS :Xylitol (Ribitol) is a five-carbon sugar alcohol derived from XYLOSE by reduction of the carbonyl group.Formule :C5H12O5Degré de pureté :99.89% - 99.96%Couleur et forme :White Solid PowderMasse moléculaire :152.15Ivacaftor
CAS :Ivacaftor (VX-770) (VX-770) is a potentiator of CFTR targeting G551D-CFTR (EC50: 100 nM) and F508del-CFTR (EC50: 25 nM) in Fisher rat thyroid cells,Formule :C24H28N2O3Degré de pureté :99% - 99.98%Couleur et forme :SolidMasse moléculaire :392.49Ref: TM-T2588
1mg38,00€5mg81,00€10mg127,00€25mg205,00€50mg304,00€100mg455,00€500mg998,00€1mL*10mM (DMSO)88,00€MDK-6983
CAS :MDK-6983 (MDK-6983) is an inhibitor of autophagy and disrupts the dynamics of actin cytoskeleton in human melanoma cells.Formule :C22H18Cl2N2O3Degré de pureté :97.55%Couleur et forme :SolidMasse moléculaire :429.3Ref: TM-T28001
1mg115,00€5mg249,00€10mg368,00€25mg562,00€50mg787,00€100mg1.054,00€500mgÀ demander1mL*10mM (DMSO)284,00€Dorsomorphin dihydrochloride
CAS :Dorsomorphin dihydrochloride (BML-275 2HCl) is a potent, selective and ATP-competitive AMPK inhibitor (Ki: 109 nM) and does not exhibit significant activity onFormule :C24H25N5O·2HClDegré de pureté :97.74% - 99.89%Couleur et forme :SolidMasse moléculaire :472.41Ref: TM-T6146
2mg35,00€5mg51,00€10mg70,00€25mg135,00€50mg235,00€100mg424,00€500mg938,00€1mL*10mM (DMSO)57,00€
