Autophagie
Les inhibiteurs de l'autophagie ciblent le processus cellulaire de l'autophagie, qui implique la dégradation et le recyclage des composants cellulaires via les lysosomes. L'autophagie est un mécanisme crucial pour maintenir l'homéostasie cellulaire, mais sa dérégulation est impliquée dans diverses maladies, y compris le cancer, les maladies neurodégénératives et les infections. Les inhibiteurs de l'autophagie peuvent bloquer ce processus, ce qui en fait des outils précieux pour étudier le rôle de l'autophagie dans les maladies et développer des stratégies thérapeutiques. Chez CymitQuimica, nous proposons des inhibiteurs de l'autophagie pour soutenir vos recherches en biologie cellulaire, oncologie et maladies neurodégénératives.
Produits appartenant à la catégorie "Autophagie"
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Tubastatin A Hydrochloride
CAS :Tubastatin A Hydrochloride (TSA HCl) is an effective and specific HDAC6 inhibitor (IC50: 15 nM).Formule :C20H21N3O2·HClDegré de pureté :97.24% - 99.15%Couleur et forme :SolidMasse moléculaire :371.86Ezetimibe
CAS :Ezetimibe (SCH 58235) is a Dietary Cholesterol Absorption Inhibitor. The physiologic effect of ezetimibe is by means of Decreased Cholesterol Absorption.Formule :C24H21F2NO3Degré de pureté :97.28% - 99.97%Couleur et forme :SolidMasse moléculaire :409.43Ref: TM-T1593
1g283,00€10mg48,00€25mg62,00€50mg77,00€100mg87,00€200mg125,00€500mg197,00€1mL*10mM (DMSO)55,00€Latrepirdine dihydrochloride
CAS :Latrepirdine dihydrochloride (Dimebolin dihydrochloride) is an orally active, and neuroactive antagonist of multiple drug targets.Formule :C21H25N3·2HClDegré de pureté :98.45%Couleur et forme :SolidMasse moléculaire :392.37Irinotecan
CAS :Irinotecan (CPT-11), a camptothecin derivative, inhibits topoisomerase I, used for colorectal cancer treatment.Formule :C33H38N4O6Degré de pureté :100% - 99.92%Couleur et forme :SolidMasse moléculaire :586.68Indole-3-Glyoxylyl Chloride
CAS :Indole-3-glyoxylyl chloride (3-Indoleglyoxylyl chloride) can be used in chemical synthesis, such as bisindolylmaleimide.Formule :C10H6ClNO2Degré de pureté :99.72%Couleur et forme :Yellow To Orange Powder Or CrystalsMasse moléculaire :207.61Ref: TM-T0618
1mg97,00€2mg145,00€5mg235,00€10mg394,00€25mg825,00€50mg1.349,00€100mg2.175,00€1mL*10mM (DMSO)379,00€Urolithin A
CAS :Urolithin A is a metabolite of ellagic acid, which inhibits DNA synthesis and induces apoptosis and autophagy. Cost-effective and quality-assured.Formule :C13H8O4Degré de pureté :99.14% - 99.66%Couleur et forme :SolidMasse moléculaire :228.2Ref: TM-T7174
5mg49,00€10mg72,00€25mg130,00€50mg187,00€100mg320,00€200mg472,00€500mg753,00€1mL*10mM (DMSO)50,00€Peiminine
CAS :1. Peiminine (Raddeanine) is an effective inhibitor for lung inflammation and pulmonary fibrosis in a rat model of bleomycin-induced lung injury.Formule :C27H43NO3Degré de pureté :99.52% - ≥95%Couleur et forme :White PowderMasse moléculaire :429.64PF-543 hydrochloride
CAS :PF-543 hydrochloride (PF-543) inhibits SphK1 with a K(i) of 3.6 nM, is sphingosine-competitive and is more than 100-fold selective for SphK1 over the SphK2Formule :C27H32ClNO4SDegré de pureté :98.90% - 99.93%Couleur et forme :SolidMasse moléculaire :502.1SBI-0640756
CAS :SBI-0640756 (SBI-756) (SBI-756) is a first-in-class inhibitor that targets eIF4G1 and disrupts the eIF4F complex.Formule :C23H14ClFN2O2Degré de pureté :99.75%Couleur et forme :SolidMasse moléculaire :404.82Ref: TM-T5173
1mg39,00€5mg87,00€10mg140,00€25mg271,00€50mg386,00€100mg540,00€200mg735,00€1mL*10mM (DMSO)93,00€Topotecan hydrochloride
CAS :Topotecan hydrochloride (NSC609699) is an antineoplastic agent used to treat ovarian cancer.Formule :C23H24ClN3O5Degré de pureté :97.88% - 98.71%Couleur et forme :White Crystalline SolidMasse moléculaire :457.92Ref: TM-T1174
1g512,00€5mg35,00€10mg51,00€25mg80,00€50mg107,00€100mg144,00€500mg344,00€1mL*10mM (DMSO)55,00€AL 8697
CAS :AL 8697 is a selective p38α MAPK inhibitor (IC50 = 6 nM) with 14-fold selectivity over p38β (IC50 = 82 nM) and 300-fold selectivity over a panel of 91 kinases.Formule :C21H21F3N4ODegré de pureté :98.96% - 99.26%Couleur et forme :SolidMasse moléculaire :402.41Ref: TM-T10277
1mg70,00€5mg145,00€10mg207,00€25mg348,00€50mg495,00€100mg678,00€500mgÀ demander1mL*10mM (DMSO)169,00€Pterostilbene
CAS :Pterostilbene is extracted from Pterocarpus indicus.Formule :C16H16O3Degré de pureté :99.20%Couleur et forme :Off-White Crystalline PowderMasse moléculaire :256.3Lapatinib ditosylate monohydrate
CAS :Lapatinib ditosylate monohydrate: a drug for advanced breast cancer; may cause liver issues.Formule :C29H26ClFN4O4S·2(C7H8O3S)·H2ODegré de pureté :98% - 99.41%Couleur et forme :Colourless To Light-Yellow CrystalMasse moléculaire :943.47KM11060
CAS :KM11060 is a novel corrector of the F508del-CFTR trafficking defect, Correcting F508del-CFTR trafficking, increasing the amount of functional CFTR at the plasmaFormule :C19H17Cl2N3O2SDegré de pureté :98.86%Couleur et forme :SolidMasse moléculaire :422.33Salvianolic acid B
CAS :Salvianolic acid B (Dan Shen Suan B) is a water-soluble antioxidant from Salvia miltiorrhiza extract with antiplatelet aggregation and antithrombotic effects.Formule :C36H30O16Degré de pureté :99.76% - 99.86%Couleur et forme :Yellow SolidMasse moléculaire :718.61YM-201636
CAS :YM201636 (IC50=33 nM), a specific PIKfyve inhibitor, is less effective to p110α and insensitive to Fabl, which is yeast orthologue.Formule :C25H21N7O3Degré de pureté :93.28% - 98.3%Couleur et forme :SolidMasse moléculaire :467.48Ref: TM-T6110
1mg48,00€2mg64,00€5mg96,00€10mg173,00€25mg359,00€50mg562,00€100mg802,00€500mg1.644,00€1mL*10mM (DMSO)97,00€Ambroxol hydrochloride
CAS :Ambroxol hydrochloride (Mucosolvan) is a metabolite of BROMHEXINE that stimulates mucociliary action and clears the air passages in the respiratory tract.Formule :C13H18Br2N2O·HClDegré de pureté :99.70%Couleur et forme :White To Yellowish Crystalline PowderMasse moléculaire :414.56Dehydrocorydaline
CAS :1.Formule :C22H24NO4Degré de pureté :99.84%Couleur et forme :SolidMasse moléculaire :366.43Ref: TM-T5S2358
1mg57,00€2mg81,00€5mg111,00€10mg160,00€25mg263,00€50mg378,00€100mg558,00€200mg797,00€1mL*10mM (DMSO)123,00€PF-06447475
CAS :PF-06447475 is a highly effective, specific, brain penetrant LRRK2 inhibitor with IC0 of 3/11 nM for wild type LRRK2 and G2019S LRRK2 respectively.Formule :C17H15N5ODegré de pureté :98.61% - 99.62%Couleur et forme :SolidMasse moléculaire :305.33DC661
CAS :DC661 is a palmitoyl-protein thioesterase 1 (PPT1) inhibitor that acts as an anti-lysosomal agent by inhibiting autophagy, demonstrating anti-cancer activity.Formule :C31H39Cl2N5Degré de pureté :99.07%Couleur et forme :SolidMasse moléculaire :552.58Ref: TM-T5538
1mg80,00€2mg105,00€5mg188,00€10mg319,00€25mg545,00€50mg780,00€100mg1.074,00€1mL*10mM (DMSO)230,00€
