Autophagie
Les inhibiteurs de l'autophagie ciblent le processus cellulaire de l'autophagie, qui implique la dégradation et le recyclage des composants cellulaires via les lysosomes. L'autophagie est un mécanisme crucial pour maintenir l'homéostasie cellulaire, mais sa dérégulation est impliquée dans diverses maladies, y compris le cancer, les maladies neurodégénératives et les infections. Les inhibiteurs de l'autophagie peuvent bloquer ce processus, ce qui en fait des outils précieux pour étudier le rôle de l'autophagie dans les maladies et développer des stratégies thérapeutiques. Chez CymitQuimica, nous proposons des inhibiteurs de l'autophagie pour soutenir vos recherches en biologie cellulaire, oncologie et maladies neurodégénératives.
Produits appartenant à la catégorie "Autophagie"
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Fludrocortisone acetate
CAS :Fludrocortisone acetate (9α-Fludrocortisone acetate) , a glucocorticoid-receptor agonist, binds to cytoplasmic receptors, translocates to the nucleus, andFormule :C23H31FO6Degré de pureté :96.92% - 98.03%Couleur et forme :Crystalline SolidMasse moléculaire :422.49(-)-Epicatechin gallate
CAS :(-)-Epicatechin gallate, a catechin isomer and strong antioxidant, affects membrane proteins and alters gA channel function in bilayers.Formule :C22H18O10Degré de pureté :96.65% - 99.72%Couleur et forme :SolidMasse moléculaire :442.37ATG12-IN-1
CAS :ATG12-IN-1 (compound 4) acts as an autophagy inhibitor targeting the ATG12-ATG3 protein-protein interaction (IC50= 9 μM), suitable for research in cancer studies.Formule :C23H15ClN4O2Couleur et forme :SolidMasse moléculaire :414.84BPO-27 racemate
CAS :BPO-27 racemate (BPO-27 (racemate)) is an effective CFTR inhibitor with IC50 of 8 nM.Formule :C26H18BrN3O6Degré de pureté :98.19%Couleur et forme :SolidMasse moléculaire :548.34Ref: TM-T10591
1mg47,00€5mg117,00€10mg170,00€25mg280,00€50mg409,00€100mg565,00€200mg758,00€1mL*10mM (DMSO)135,00€Quercetin
CAS :Quercetin (Sophoretin) is a natural flavonoid and is an agonist of SIRT1.Formule :C15H10O7Degré de pureté :96.29% - 98.05%Couleur et forme :Sensitive To Exposure To Air And Light Insoluble In Water Alcoholic Solutions Taste Very Bitter (Ntp 1992)Masse moléculaire :302.24Cediranib
CAS :Cediranib (AZD2171) is a potent KDR tyrosine kinase inhibitor (IC50 < 1nM), also targets Flt1/4, PDGFRβ, c-Kit, and more selective for VEGFR.Formule :C25H27FN4O3Degré de pureté :97.21% - 99.94%Couleur et forme :SolidMasse moléculaire :450.51Ref: TM-T2500
2mg42,00€5mg63,00€10mg92,00€25mg136,00€50mg177,00€100mg254,00€200mg462,00€500mg742,00€1mL*10mM (DMSO)69,00€Ursolic acid
CAS :Ursolic acid (Prunol) is a natural pentacyclic triterpene carboxylic acid. Ursolic acid has anti-tumor and anti-inflammatory effects. Cost-effective and quality-assured.Formule :C30H48O3Degré de pureté :99.66% - 99.79%Couleur et forme :Platelets From Alcohol SolidMasse moléculaire :456.7LY294002
CAS :LY294002 (SF 1101) is a broad-spectrum inhibitor of PI3K, inhibiting PI3Kα, PI3Kδ, and PI3Kβ (IC50=0.5/0.57/0.97 μM).Formule :C19H17NO3Degré de pureté :98% - 99.96%Couleur et forme :Pale Yellow SolidMasse moléculaire :307.34Nobiletin
CAS :Nobiletin: a citrus-derived flavone with anti-inflammatory and anti-cancer properties; water-insoluble, very weak acid.Formule :C21H22O8Degré de pureté :98.78% - 99.76%Couleur et forme :SolidMasse moléculaire :402.39Ref: TM-T2834
5mg57,00€10mg88,00€25mg124,00€50mg168,00€100mg265,00€200mg393,00€500mg653,00€1mL*10mM (DMSO)59,00€Sinomenine
CAS :Sinomenine (Kukoline) is a pure alkaloid isolated from the Sinomenium acutum, is utilized in the treatment of rheumatism and arthritis.Formule :C19H23NO4Degré de pureté :99.02% - 99.89%Couleur et forme :White PowderMasse moléculaire :329.39Sulfosuccinimidyl oleate
CAS :Sulfosuccinimidyl oleate (Sulfo-N-succinimidyl oleate) (Sulfo-N-succinimidyl oleate) is a long chain fatty acid that inhibits fatty acid transport into cells.Formule :C22H37NO7SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :459.6Tubastatin A
CAS :Tubastatin A: Selective HDAC6 inhibitor, IC50 of 15 nM, 1000x less effective on other isozymes except HDAC8.Formule :C20H21N3O2Degré de pureté :97.22% - 99.51%Couleur et forme :SolidMasse moléculaire :335.4Ref: TM-T1966
10mg48,00€25mg64,00€50mg79,00€100mg111,00€200mg169,00€500mg274,00€1mL*10mM (DMSO)47,00€N-Benzylpalmitamide
CAS :N-Benzylpalmitamide (Macamide 1) inhibits fatty acid amide hydrolase (FAAH) in a time-dependent manner and could potentially offer a good alternative for theFormule :C23H39NODegré de pureté :97.08% - 99.77%Couleur et forme :SolidMasse moléculaire :345.56LG-100064
CAS :LG-100064 is an agonist of retinoid-X-receptor (RXR)(EC50s of 330 nM, 200 nM, and 260 nM for RXRα, RXRβ and RXRγ)Formule :C23H26O3Degré de pureté :98.65%Couleur et forme :SolidMasse moléculaire :350.45Ref: TM-T11844
2mg47,00€5mg70,00€10mg97,00€25mg167,00€50mg249,00€100mg369,00€200mg545,00€1mL*10mM (DMSO)77,00€Icaritin
CAS :Icaritin (Anhydroicaritin) has hormone regulation activity and cardiovascular function improvement activity.Formule :C21H20O6Degré de pureté :97.69% - 98.96%Couleur et forme :SolidMasse moléculaire :368.38EAD1
CAS :EAD1 is a useful organic compound for research related to life sciences. The catalog number is T35329 and the CAS number is 1644388-26-0.Formule :C24H27Cl2N7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :484.42R1487 Hydrochloride
CAS :R1487 Hydrochloride (R1487 (Hydrochloride)) is an orally bioavailable and highly selective inhibitors of p38α.Formule :C19H19ClF2N4O3Degré de pureté :99.42%Couleur et forme :SolidMasse moléculaire :424.834E2RCat
CAS :4E2RCat is an inhibitor of eIF4E-eIF4G interaction (IC50 = 13.5 μM) and is capable of blocking coronavirus replication as monitored by viral protein expressionFormule :C22H14ClNO4S2Degré de pureté :96.48%Couleur et forme :SolidMasse moléculaire :455.93Onjisaponin B
CAS :Onjisaponin B induces autophagy via the AMPK-mTOR signaling pathway, increases the NGF level and accelerates both the removal of mutant huntingtin and A53T α±-Formule :C75H112O35Degré de pureté :99.20% - 99.88%Couleur et forme :SolidMasse moléculaire :1573.67Rilmenidine Phosphate
CAS :Rilmenidine Phosphate is a selective I(1) imidazoline receptor agonist, used to treat hypertension.Formule :C10H19N2O5PDegré de pureté :99.87% - ≥95%Couleur et forme :SolidMasse moléculaire :278.24Ref: TM-T6641
1mg40,00€5mg88,00€10mg137,00€25mg264,00€50mg418,00€100mg627,00€500mg1.301,00€1mL*10mM (DMSO)87,00€
