Autophagie
Les inhibiteurs de l'autophagie ciblent le processus cellulaire de l'autophagie, qui implique la dégradation et le recyclage des composants cellulaires via les lysosomes. L'autophagie est un mécanisme crucial pour maintenir l'homéostasie cellulaire, mais sa dérégulation est impliquée dans diverses maladies, y compris le cancer, les maladies neurodégénératives et les infections. Les inhibiteurs de l'autophagie peuvent bloquer ce processus, ce qui en fait des outils précieux pour étudier le rôle de l'autophagie dans les maladies et développer des stratégies thérapeutiques. Chez CymitQuimica, nous proposons des inhibiteurs de l'autophagie pour soutenir vos recherches en biologie cellulaire, oncologie et maladies neurodégénératives.
Produits appartenant à la catégorie "Autophagie"
Trier par
3PO
CAS :3PO inhibits PFKFB3 (IC50: 22.9 µM) and cancer cell growth (IC50: 1.4-24 µM), reducing glucose uptake and key cellular metabolites.Formule :C13H10N2ODegré de pureté :97.76% - 99.67%Couleur et forme :SolidMasse moléculaire :210.23Ref: TM-T22223
5mg57,00€10mg81,00€25mg127,00€50mg188,00€100mg340,00€200mg507,00€500mg807,00€1mL*10mM (DMSO)64,00€Emodin
CAS :Emodin, a plant-derived anthraquinone, inhibits Y cell growth via various signaling pathways.Formule :C15H10O5Degré de pureté :94.4% - 98.9%Couleur et forme :Physical Description Orange Needles Or Powder (Ntp 1992)Masse moléculaire :270.24Cucurbitacin B
CAS :Cucurbitacin B (Cuc B) has profound in vitro and in vivo antiproliferative effects against human pancreatic Y cells.Formule :C32H46O8Degré de pureté :97.10% - 99.33%Couleur et forme :SolidMasse moléculaire :558.7EIPA
CAS :EIPA (L593754) is a TRPP3 channel inhibitor and an inhibitor of Na+/H+ exchange (NHE). EIPA inhibits megacytosis, promotes autophagy. Cost-effective and quality-assured.Formule :C11H18ClN7ODegré de pureté :96.62% - 98.52%Couleur et forme :Off-White To Yellow SolidMasse moléculaire :299.76Schisandrol B
CAS :Schisandrol B fights neuroinflammation, liver/renal damage, and reduces cell growth via multiple signaling pathways.Formule :C23H28O7Degré de pureté :99.14% - 99.32%Couleur et forme :SolidMasse moléculaire :416.46Ref: TM-T6S1917
5mg71,00€10mg96,00€25mg202,00€50mg303,00€100mg452,00€500mg1.035,00€1mL*10mM (DMSO)79,00€Mdivi-1
CAS :Mdivi-1 (Mitochondrial division inhibitor 1) is a mitochondrial division inhibitor that inhibits DRP1 and Dynamin I (IC50=1-10 μM).Formule :C15H10Cl2N2O2SDegré de pureté :96.57% - 99.6%Couleur et forme :SolidMasse moléculaire :353.22Ref: TM-T1907
5mg47,00€10mg56,00€25mg90,00€50mg153,00€100mg227,00€200mg338,00€500mg558,00€1mL*10mM (DMSO)50,00€Turofexorate Isopropyl
CAS :Turofexorate Isopropyl (XL335) is a potent, selective, and orally bioavailable FXR agonist with EC50 of 4 nMFormule :C25H24F2N2O3Degré de pureté :99.33% - 99.73%Couleur et forme :SolidMasse moléculaire :438.47ROC-325
CAS :ROC-325: orally active autophagy inhibitor with anticancer effects, induces kidney cancer cell death; selective action.Formule :C28H27ClN4OSDegré de pureté :99.26%Couleur et forme :SolidMasse moléculaire :503.06Ref: TM-T16777
1mg35,00€2mg47,00€5mg64,00€10mg97,00€25mg188,00€50mg311,00€100mg449,00€500mgÀ demanderOlaparib
CAS :View and buy Olaparib from TargetMol.Olaparib is a small molecule inhibitor of PARP1/PARP2.Cited in 10 publications.Formule :C24H23FN4O3Degré de pureté :100% - 99.90%Couleur et forme :SolidMasse moléculaire :434.46Autophagy-IN-6
Autophagy-IN-6 (compound 1u) is an inhibitor of lysosomal autophagy that induces the accumulation of the LC3-II protein. Additionally, it exhibits antiproliferative activity.Formule :C28H43N3O3Couleur et forme :SolidMasse moléculaire :469.66MRT68921
CAS :MRT68921 is a potent and dual autophagy kinase ULK1/2 inhibitor with IC50 of 2.9 nM and 1.1 nM, respectively.Formule :C25H34N6ODegré de pureté :99.23%Couleur et forme :SolidMasse moléculaire :434.58Trimetazidine dihydrochloride
CAS :Trimetazidine, an anti-ischemic agent, enhances myocardial glucose use, inhibits fat metabolism, and helps with angina.Formule :C14H24Cl2N2O3Degré de pureté :99.58%Couleur et forme :Crystalline SolidMasse moléculaire :339.258Dexamethasone acetate
CAS :Dexamethasone acetate (NSC 39471) is a potent anti-inflammatory steroid, blocks NF-kB, and lacks salt-retention.Formule :C24H31FO6Degré de pureté :99.22% - 99.65%Couleur et forme :White Or Almost White Crystalline PowderMasse moléculaire :434.5Bardoxolone Methyl
CAS :Bardoxolone Methyl (TP-155) is a synthetic triterpenoid that acts as an activator of the Nrf2 pathway and an inhibitor of the NF-κB pathway with potential anti-Formule :C32H43NO4Degré de pureté :97.81% - 99.09%Couleur et forme :SolidMasse moléculaire :505.69Ref: TM-T6165
10mg47,00€25mg65,00€50mg88,00€100mg119,00€200mg187,00€500mg424,00€1mL*10mM (DMSO)50,00€FIPI
CAS :FIPI, a halopemide derivative, strongly blocks PLD1 and PLD2 (IC50s: 25 nM, 20 nM) and hinders PLD-mediated cell activity.Formule :C23H24FN5O2Degré de pureté :98.01% - 99.08%Couleur et forme :SolidMasse moléculaire :421.47Etoposide
CAS :Etoposide (VP-16-213) is a topoisomerase II inhibitor that inhibits DNA synthesis by forming a complex with topoisomerase II and DNA (IC50=60.3 μM).Formule :C29H32O13Degré de pureté :99.19% - 99.94%Couleur et forme :Crystals From Methanol SolidMasse moléculaire :588.56Diosgenin glucoside
CAS :Diosgenin glucoside (Trillin) and other synthetic glycosides with similar activities may be of use in the management of hypercholesterolemia and atherosclerosisFormule :C33H52O8Degré de pureté :97.17% - 99.44%Couleur et forme :SolidMasse moléculaire :576.76Leonurine
CAS :Leonurine (SCM-198) is an alkaloid that has been found in H. leonuri and with anti-oxidative and anti-inflammatory.Formule :C14H21N3O5Degré de pureté :98.55%Couleur et forme :White Crystalline PowderMasse moléculaire :311.33Pentoxifylline
CAS :Pentoxifylline (PTX) stimulates cytokines, inhibits phosphodiesterase, enhances blood flow, and increases cell flexibility.Formule :C13H18N4O3Degré de pureté :99.26% - 99.96%Couleur et forme :SolidMasse moléculaire :278.31UM-164
CAS :UM-164 (DAS-DFGO-II), a highly potent c-Src inhibitor with a dissociation constant (Kd) of 2.7 nM, also effectively inhibits p38α and p38β.Formule :C30H31F3N8O3SDegré de pureté :98.72% - 99.52%Couleur et forme :SolidMasse moléculaire :640.68
