Autophagie
Les inhibiteurs de l'autophagie ciblent le processus cellulaire de l'autophagie, qui implique la dégradation et le recyclage des composants cellulaires via les lysosomes. L'autophagie est un mécanisme crucial pour maintenir l'homéostasie cellulaire, mais sa dérégulation est impliquée dans diverses maladies, y compris le cancer, les maladies neurodégénératives et les infections. Les inhibiteurs de l'autophagie peuvent bloquer ce processus, ce qui en fait des outils précieux pour étudier le rôle de l'autophagie dans les maladies et développer des stratégies thérapeutiques. Chez CymitQuimica, nous proposons des inhibiteurs de l'autophagie pour soutenir vos recherches en biologie cellulaire, oncologie et maladies neurodégénératives.
Produits appartenant à la catégorie "Autophagie"
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Rosuvastatin calcium
CAS :Rosuvastatin calcium (ZD4522) , a selective and competitive inhibitor of hepatic hydroxymethyl-glutaryl coenzyme A (HMG-CoA) reductase, has antilipidemicFormule :(C22H27FN3O6S)CaDegré de pureté :98.85% - 99.68%Couleur et forme :White To Off-White Crystalline SolidMasse moléculaire :1001.14SKF-96365 hydrochloride
CAS :SKF-96365 hydrochloride (SKF96365) , a SOCE inhibitor, exhibits potent anti-neoplastic activity by inducing cell-cycle arrest and apoptosis in colorectal YFormule :C22H27ClN2O3Degré de pureté :99.48% - 99.85%Couleur et forme :SolidMasse moléculaire :402.91Ref: TM-T2170
5mg57,00€10mg86,00€25mg138,00€50mg243,00€100mg470,00€200mg717,00€500mg1.111,00€1mL*10mM (DMSO)63,00€Hydroxychloroquine
CAS :HCQ, an anti-malarial, may induce cancer cell death and is being explored for COVID-19.Formule :C18H26ClN3ODegré de pureté :99.79%Couleur et forme :SolidMasse moléculaire :335.87Cilostazol
CAS :Cilostazol (OPC 21) is a Phosphodiesterase 3 Inhibitor. The mechanism of action of cilostazol is as a Phosphodiesterase 3 Inhibitor.Formule :C20H27N5O2Degré de pureté :99.58% - 99.90%Couleur et forme :Off-White SolidMasse moléculaire :369.46Gambogic Acid
CAS :Gambogic Acid (Guttic Acid) ( EC50=0.78-1.64 uM) activates caspases.Formule :C38H44O8Degré de pureté :97.16% - 98.67%Couleur et forme :SolidMasse moléculaire :628.75Ref: TM-T6185
2mg39,00€5mg55,00€10mg77,00€25mg111,00€50mg160,00€100mg227,00€500mg560,00€1mL*10mM (DMSO)88,00€Sofalcone
CAS :Sofalcone (SU-88), a gastric antiulcer agent in clinical use, is known to induce the expression of Heme oxygenase-1 (HO-1) in gastric epithelium.Formule :C27H30O6Degré de pureté :97.55%Couleur et forme :SolidMasse moléculaire :450.52SB 202190
CAS :SB 202190 (FHPI) is a p38 MAPK inhibitor that inhibits p38α and p38β2 (IC50=50/100 nM) selectively and cell-permeably.Formule :C20H14FN3ODegré de pureté :98% - 99.84%Couleur et forme :Pale YellowMasse moléculaire :331.34Diazoxide
CAS :Diazoxide (Proglycem) is a benzothiadiazine derivative that is a peripheral vasodilator used for hypertensive emergencies.Formule :C8H7ClN2O2SDegré de pureté :99% - 99.83%Couleur et forme :SolidMasse moléculaire :230.67Nitazoxanide
CAS :Nitazoxanide (NSC-697855) is a synthetic benzamide antiprotozoal; it disrupts pyruvate electron transfer reactions.Formule :C12H9N3O5SDegré de pureté :97.20% - 99.53%Couleur et forme :SolidMasse moléculaire :307.28Ref: TM-T1546
1g750,00€5mg35,00€10mg51,00€25mg90,00€50mg139,00€100mg207,00€200mg311,00€500mg520,00€1mL*10mM (DMSO)55,00€Belinostat
CAS :Belinostat (PXD101) is an inhibitor of hydroxamic acid-type histone deacetylase (HDAC, IC50 of 27 nM in HeLa cell extracts),and with antineoplastic activity.Formule :C15H14N2O4SDegré de pureté :100% - 99.75%Couleur et forme :SolidMasse moléculaire :318.35Ref: TM-T8517
5mg48,00€10mg69,00€25mg97,00€50mg144,00€100mg207,00€200mg306,00€500mg518,00€1mL*10mM (DMSO)63,00€AS1842856
CAS :AS1842856 is a Foxo1 inhibitor that blocks the transcriptional activity of Foxo1. AS1842856 has autophagy inhibitory activity. Cost-effective and quality-assured.Formule :C18H22FN3O3Degré de pureté :100% - 99.56%Couleur et forme :SolidMasse moléculaire :347.38SP-8356
CAS :SP-8356 is a potent, orally active inhibitor of cluster of differentiation 147 (CD147) with anti-atherosclerotic effects.Formule :C18H20O4Degré de pureté :98.24%Couleur et forme :SolidMasse moléculaire :300.35Ref: TM-T12981
1mg70,00€5mg156,00€10mg238,00€25mg449,00€50mg610,00€100mg815,00€200mg1.103,00€1mL*10mM (DMSO)170,00€Megestrol acetate
CAS :Megestrol acetate (BDH1298) is an oral progestogen with anti-androgenic properties, used for endometrial and breast cancer, anorexia, and cachexia.Formule :C24H32O4Degré de pureté :99.46%Couleur et forme :Crystalline SolidMasse moléculaire :384.51GANT 61
CAS :GANT 61 (GANT61) is an inhibitor for Gli1 and Gli2.Formule :C27H35N5Degré de pureté :100% - ≥95%Couleur et forme :SolidMasse moléculaire :429.6TTNPB
CAS :TTNPB (Ro 13-7410,AGN-191183), a potent RAR agonist, inhibits binding of [3H]tRA of human RARα (IC50: 5.1 nM), β (IC50: 4.5 nM), and γ (IC50: 9.3 nM),Formule :C24H28O2Degré de pureté :99.55%Couleur et forme :White SolidMasse moléculaire :348.48Ref: TM-T1288
2mg39,00€5mg57,00€10mg87,00€25mg162,00€50mg306,00€100mg464,00€500mg1.008,00€1mL*10mM (DMSO)59,00€Valproic acid sodium salt
CAS :Sodium valproate is an anti-epileptic, boosting brain GABA levels and possibly affecting potassium channels for membrane stability.Formule :C8H15NaO2Degré de pureté :99% - 99.78%Couleur et forme :White PowderMasse moléculaire :166.2Dinoprost tromethamine salt
CAS :Dinoprost tromethamine salt (PGF2α THAM) is a naturally occurring prostaglandin used in medicine to induce labor and as an abortifacient.Formule :C24H45NO8Degré de pureté :99.73%Couleur et forme :Natural Form Crystals SolidMasse moléculaire :475.62BIX-01294 trihydrochloride
CAS :BIX-01294 trihydrochloride is an inhibitor of G9a histone methyltransferase.In a cell-free assay, the IC50=2.7 μM for G9a histone methyltransferase.Formule :C28H38N6O2·3HClDegré de pureté :99.41% - 99.95%Couleur et forme :SolidMasse moléculaire :600.02Ref: TM-T1959
1mg44,00€2mg55,00€5mg71,00€10mg107,00€25mg192,00€50mg274,00€100mg492,00€500mg1.103,00€1mL*10mM (DMSO)139,00€Salicylic acid
CAS :Salicylic acid (2-Hydroxybenzoic acid), a natural compound extracted from Willow bark, is an anti-inflammatory inhibitor of activity cyclooxygenase.Formule :C7H6O3Degré de pureté :98.04% - 98.83%Couleur et forme :White Solid PowderMasse moléculaire :138.12CFTR corrector 2
CAS :CFTR corrector 2 (FDL169) is a novel and potent CFTR corrector for treating cystic fibrosis (CF) patients who carry the F508del mutation.Formule :C27H23FN4O4Degré de pureté :99.66%Couleur et forme :SolidMasse moléculaire :486.49Ref: TM-T5312
2mg39,00€5mg58,00€10mg85,00€25mg156,00€50mg226,00€100mg335,00€200mg469,00€1mL*10mM (DMSO)63,00€
