Récepteur de la dopamine
Les récepteurs de la dopamine sont un groupe de récepteurs couplés aux protéines G (GPCR) qui répondent au neurotransmetteur dopamine, jouant un rôle clé dans la régulation du mouvement, de la motivation, de la récompense et de plusieurs fonctions cognitives. Ces récepteurs sont divisés en familles de type D1 et de type D2, chacune ayant des fonctions et des profils pharmacologiques distincts. Les modulateurs des récepteurs de la dopamine sont largement étudiés pour leurs applications dans le traitement de la maladie de Parkinson, de la schizophrénie, de la dépendance et d'autres troubles neuropsychiatriques. Chez CymitQuimica, nous offrons une large gamme de modulateurs de récepteurs de la dopamine de haute qualité pour soutenir vos recherches en neurosciences, santé mentale et signalisation GPCR.
Produits appartenant à la catégorie "Récepteur de la dopamine"
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Fallypride
CAS :Fallypride is a potent and selective dopamine D2/D3 receptor antagonist.Formule :C20H29FN2O3Degré de pureté :100% - 99.17%Couleur et forme :SolidMasse moléculaire :364.45Ref: TM-T70302
1mg359,00€5mg842,00€10mg1.035,00€25mg1.663,00€50mg2.072,00€100mg2.660,00€1mL*10mM (DMSO)677,00€Loxapine succinate
CAS :Loxapine succinate (Loxapac), a D2DR and D4DR inhibitor, is utilized in schizophrenia.Formule :C22H24ClN3O5Degré de pureté :99.69%Couleur et forme :White To Of-White SolidMasse moléculaire :445.95-HT7R antagonist 3
CAS :Compound 6.4, also known as 5-HT7R antagonist 3, is a selective antagonist of the 5-HT7R with a Ki of 8 nM. It exhibits significantly less affinity towards D2R, 5-HT1AR, and 5-HT2AR with Ki values of 511 nM, 8930 nM, and 5786 nM, respectively. In mice, 5-HT7R antagonist 3 demonstrates anti-depressant and anti-anxiety activities.Formule :C30H33FN4O3Couleur et forme :SolidMasse moléculaire :516.61Pericyazine
CAS :Pericyazine (Propericiazine) is a selective D2-dopamine receptor antagonist.Formule :C21H23N3OSDegré de pureté :99.61%Couleur et forme :SolidMasse moléculaire :365.49Ref: TM-T16472
1mg46,00€2mg59,00€5mg93,00€10mg124,00€25mg235,00€50mg389,00€100mg567,00€500mg1.225,00€1mL*10mM (DMSO)77,00€Piribedil
CAS :Piribedil (Trivastan) is a dopamine D2 agonist, used in the treatment of Parkinson's disease.Formule :C16H18N4O2Degré de pureté :99.79% - 99.91%Couleur et forme :SolidMasse moléculaire :298.34Fananserin
CAS :Fananserin: Oral 5-HT2A antagonist (Ki=0.37 nM, rat), blocks human D4 receptor (Ki=2.93 nM).Formule :C23H24FN3O2SDegré de pureté :99.78%Couleur et forme :SolidMasse moléculaire :425.52Ref: TM-T15270
2mg42,00€5mg56,00€10mg81,00€25mg116,00€50mg170,00€100mg250,00€200mg369,00€1mL*10mM (DMSO)62,00€Fipexide
CAS :Fipexide (Attentil, Vigilor), a psychoactive drug of the piperazine chemical class, was developed in Italy in 1983.Formule :C20H21ClN2O4Degré de pureté :99.95%Couleur et forme :SolidMasse moléculaire :388.84Lurasidone
CAS :Lurasidone (SM-13496) is an antagonist of both dopamine D2 and 5-HT7(IC50=1.68 and 0.495 nM, respectively).It also a partial agonist of 5-HT1A receptor(IC50 : 6Formule :C28H36N4O2SDegré de pureté :99.5%Couleur et forme :SolidMasse moléculaire :492.68(Rac)-Rotigotine hydrochloride
CAS :(Rac)-Rotigotine hydrochloride is a racemate of Rotigotine. Rotigotine is a full agonist of dopamine receptor, a partial the 5-HT1A receptor agonist.Formule :C19H26ClNOSCouleur et forme :SolidMasse moléculaire :351.93Docosahexaenoic acid ethyl ester
CAS :Docosahexaenoic acid ethyl ester (Ethyl docosahexaenoate) enhances 6-hydroxydopamine-induced neuronal damage by inducing lipid peroxidation in the mouse striatum, and can be used to study oxidative diseases of the retina or neurons.Formule :C24H36O2Couleur et forme :SolidMasse moléculaire :356.54Amantadine hydrochloride
CAS :Amantadine hydrochloride (CI-719) is an antiviral that is used in the prophylactic or symptomatic treatment of influenza A and Parkinson disease.Formule :C10H18ClNDegré de pureté :99.98%Couleur et forme :Solid CrystallineMasse moléculaire :187.71Sonepiprazole
CAS :Sonepiprazole (PNU-101387G) is a chemical compound known for its selective antagonistic properties toward D4 dopamine receptors, exhibiting dissociationFormule :C21H27N3O3SDegré de pureté :99.31%Couleur et forme :SolidMasse moléculaire :401.52Ref: TM-T23380
2mg38,00€5mg58,00€10mg94,00€25mg180,00€50mg306,00€100mg442,00€200mg622,00€1mL*10mM (DMSO)71,00€UCM-1306
CAS :UCM-1306: an oral dopamine D1 receptor PAM; boosts DA efficacy, may enhance motor and cognitive function in PD.Formule :C14H14FNO2SDegré de pureté :100%Couleur et forme :SoildMasse moléculaire :279.33Ansofaxine hydrochloride
CAS :Ansofaxine hydrochloride (LY03005) is a serotonin-norepinephrine-dopamine reuptake inhibitor (IC50s: 723, 763 and 491 nM, respectively).Formule :C24H32ClNO3Degré de pureté :99.57% - 99.77%Couleur et forme :SolidMasse moléculaire :417.97Paliperidone
CAS :Paliperidone (9-hydroxyrisperidone)(Invega) is used as an atypical antipsychotic.Formule :C23H27FN4O3Degré de pureté :95% - 99.08%Couleur et forme :Off White To Light Orange Coloured SolidMasse moléculaire :426.48Mesdopetam hemitartrate
CAS :Mesdopetam hemitartrate antagonizes dopamine D3 receptor (Ki=90 nM; IC50=9.8 μM) and stabilizes psychomotor function.Formule :C28H42F2N2O12S2Degré de pureté :99.98%Couleur et forme :SolidMasse moléculaire :700.77Lumateperone
CAS :Lumateperone (ITI 722) is a 5HT2A receptor antagonist and a dopamine receptor phosphoprotein modulator (DPPM).Formule :C24H28FN3ODegré de pureté :99.77%Couleur et forme :SolidMasse moléculaire :393.5Haloperidol
CAS :Haloperidol (Serenace) is a highly potent neuroleptic by relieving nervous through the depression of nerve function.Formule :C21H23ClFNO2Degré de pureté :98.69% - 98.97%Couleur et forme :Crystals SolidMasse moléculaire :375.86Moperone
CAS :Moperone (R 1658) is an antagonist of both the D2 dopamine receptor (D2 dopamine receptor) and the D3 dopamine receptor (D3 dopamine receptor), with IC50 values for each of 1.0 nM.Formule :C22H26FNO2Couleur et forme :SolidMasse moléculaire :355.45PD-168077 maleate
CAS :PD-168077 maleate is a selective agonist of dopamine D4 receptor(Ki : 9 nM)Formule :C24H26N4O5Degré de pureté :98.82%Couleur et forme :SolidMasse moléculaire :450.49Ref: TM-T5047
2mg35,00€5mg52,00€10mg80,00€25mg150,00€50mg245,00€100mg364,00€200mg517,00€1mL*10mM (DMSO)58,00€L-745870 hydrochloride
CAS :L-745870 hydrochloride has excellent brain penetration. L-745870 hydrochloride is a high-affinity, selective and orally active human dopamine D4 receptorFormule :C18H20Cl2N4Degré de pureté :97.36%Couleur et forme :SolidMasse moléculaire :363.28Ref: TM-T11799
5mg40,00€10mg65,00€25mg111,00€50mg178,00€100mg259,00€200mg374,00€1mL*10mM (DMSO)34,00€Levosulpiride
CAS :Levosulpiride (S-(-)-Sulpiride) is the (S)-enantiomer of sulpiride, which is a D2 receptor antagonist, an atypical antipsychotic drug of the benzamide class.Formule :C15H23N3O4SDegré de pureté :98.20% - 99.88%Couleur et forme :White Crystalline PowderMasse moléculaire :341.43Diclofensine hydrochloride
CAS :Diclofensine hydrochloride (Ro 8-4650 hydrochloride) 是一种高效单胺再摄取抑制剂,在大鼠脑突触体中能够阻断多巴胺 (IC50=0.74 nM)、去甲肾上腺素 (IC50=2.3 nM) 和 5-羟色胺 (IC50=3.7 nM)。Formule :C17H18Cl3NODegré de pureté :98.86% - 99.93%Couleur et forme :SolidMasse moléculaire :358.69FAUC 213
CAS :FAUC 213 is a selective full antagonist of the dopamine D4 receptor.Formule :C18H19ClN4Degré de pureté :99.84%Couleur et forme :SolidMasse moléculaire :326.82Nomifensine maleate
CAS :Nomifensine maleate (Nomifensine (maleate)) is a selective inhibitor of dopamine uptake. Nomifensine maleate is used in adult attention deficit disorder.Formule :C20H22N2O4Degré de pureté :98.46%Couleur et forme :SolidMasse moléculaire :354.4Tolnapersine
CAS :Tolnapersine is a mixed dopamine agonist and alpha-adrenoceptor antagonist.Formule :C21H26N2ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :322.44Clozapine
CAS :Clozapine (HF 1854) is a tricylic dibenzodiazepine, classified as an atypical antipsychotic agent.Formule :C18H19ClN4Degré de pureté :99.91% - 99.93%Couleur et forme :Yellow Crystals From Acetone-Petroleum Ether SolidMasse moléculaire :326.82Ref: TM-T0455
1g449,00€10mg35,00€25mg52,00€50mg70,00€100mg96,00€200mg170,00€500mg303,00€1mL*10mM (DMSO)47,00€Brexpiprazole HCl
CAS :Brexpiprazole HCl (OPC 34712 dihydrochloride) is a new antipsychotic drug.Formule :C25H27N3O2S·xHClDegré de pureté :99.05%Couleur et forme :SolidMasse moléculaire :433.6Ref: TM-T8690
1mg131,00€5mg286,00€10mg430,00€25mg710,00€50mg998,00€100mg1.349,00€500mg2.688,00€1mL*10mM (DMSO)338,00€A-381393
CAS :A-381393 is a selective and brain penetrate dopamine D4 receptor antagonist (Kis: 1.9/1.5/1.6 nM for human dopamine D4.2/D4.4/D4.7 receptor).Formule :C20H24N4Degré de pureté :99.00%Couleur et forme :SolidMasse moléculaire :320.43Ref: TM-T5397
1mg40,00€5mg80,00€10mg117,00€25mg210,00€50mg304,00€100mg437,00€200mg615,00€1mL*10mM (DMSO)88,00€Hirsuteine
CAS :Hirsuteine: natural product; blocks nicotine effects on dopamine by hindering ion flow in receptor channels.Formule :C22H26N2O3Degré de pureté :99.36% - 99.63%Couleur et forme :SolidMasse moléculaire :366.45Pramipexole dihydrochloride
CAS :Pramipexole dihydrochloride could be used to treat Parkinson disease.Formule :C10H18ClN3SDegré de pureté :98%Couleur et forme :White Crystalline PowderMasse moléculaire :247.79D1R antagonist 1
CAS :Compound 12a (D1R antagonist 1) is a D1R antagonist that participates in both G-protein-coupled and β-arrestin-mediated signaling pathways [1].Formule :C22H26BrNO4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :448.35Tetrahydropalmatine hydrochloride
CAS :Tetrahydropalmatine HCl (Gindarine) is a muscle relaxant alkaloid from Corydalis plants.Formule :C21H26ClNO4Degré de pureté :98% - 99.59%Couleur et forme :SolidMasse moléculaire :391.888PF2562
CAS :PF2562: Dopamine D1 ligand, agonist/partial agonist. Binds D1 receptor (Ki: 113 nM), active in cAMP assay (EC50: 568 nM).Formule :C19H17N5ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :331.37AHN 1-055 hydrochloride
CAS :AHN 1-055 hydrochloride (3α-Bis-(4-fluorophenyl) Methoxytropane hydrochloride) is an inhibitor of dopamine transporter (DAT) and dopamine uptake(IC50 = 71 nM).Formule :C21H24ClF2NODegré de pureté :99.60%Couleur et forme :SolidMasse moléculaire :379.87Ref: TM-T39429
2mg35,00€5mg52,00€10mg80,00€25mg137,00€50mg202,00€100mg311,00€200mg467,00€1mL*10mM (DMSO)52,00€Talipexole dihydrochloride
CAS :Talipexole dihydrochloride (Domnin) is a dopamine D2 receptor agonist, α2-adrenoceptor agonist, and 5-HT3 receptor antagonist in both rat cortical andFormule :C10H17Cl2N3SDegré de pureté :98.64%Couleur et forme :Light Yellow SolidMasse moléculaire :282.23Ref: TM-T14490
2mg38,00€5mg56,00€10mg89,00€25mg154,00€50mg264,00€100mg424,00€200mg613,00€500mg949,00€1mL*10mM (DMSO)63,00€PNU-96391
CAS :PNU-96391 (OSU-6162) is an antagonist of dopamine D2 and a partial agonist of 5-HT2A. PNU-96391 can be used in research on the treatment of chronic diseases.Formule :C15H23NO2SDegré de pureté :99.76%Couleur et forme :SolidMasse moléculaire :281.41Ref: TM-T28435
1mg115,00€5mg249,00€10mg369,00€25mg562,00€50mg787,00€100mg1.054,00€200mg1.406,00€1mL*10mM (DMSO)235,00€Veralipride
CAS :Veralipride ((±)-Veralipride) is an antagonist of D2 receptor.Formule :C17H25N3O5SDegré de pureté :99.65%Couleur et forme :SolidMasse moléculaire :383.46N-0500 HCl
CAS :N-0500 HCl, a potent DA receptor agonist, displaces [3H]DP_x005f_x0002_5,6-ADTN with an IC50 of 3nM.Formule :C15H22ClNO2Degré de pureté :98.3% - 98.42%Couleur et forme :SolidMasse moléculaire :283.79SK609 HCl
CAS :SK609 HCl is a selective dopamine D3 receptor agonist. It also has atypical signaling properties.Formule :C10H15Cl2NDegré de pureté :99.02%Couleur et forme :SolidMasse moléculaire :220.14SCH-23390 maleate
CAS :SCH-23390 maleate (R-(+)-SCH-23390 maleate) is a potent and selective antagonist of dopamine D1-like receptor (1 and D5 receptor with Kis of 0.2 nM and 0.3 nM,Formule :C21H22ClNO5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :403.86Flibanserin
CAS :Flibanserin (Girosa) is a serotonergic antidepressant used to treat hypoactive sexual desire disorder.Formule :C20H21F3N4ODegré de pureté :99.37% - 99.93%Couleur et forme :White PowderMasse moléculaire :390.4Tetrahydropalmatine
CAS :Tetrahydropalmatine (DL-Tetrahydropalmatine) is an active component isolated from corydalis, suppressing amygdaloid release of dopamine to inhibit an epilepticFormule :C21H25NO4Degré de pureté :99.91% - 99.95%Couleur et forme :SolidMasse moléculaire :355.43FGH31
FGH31 (Compound 24), a dopamine D4 agonist, exhibits potent and selective GRK2-dependency with a K i of 1.6 nM and partially activates β-arrestin [1].Formule :C33H36N4O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :520.66NGB 2904
CAS :NGB 2904 is a potent and selective antagonist of dopamine D3 receptor. NGB2904 potently antagonizes mitogenesis stimulated by quinpirole (IC50 = 6.8 nM).Formule :C28H29Cl2N3ODegré de pureté :98.79%Couleur et forme :SolidMasse moléculaire :494.46Ref: TM-T28167
2mg40,00€5mg58,00€10mg90,00€25mg163,00€50mg279,00€100mg394,00€500mgÀ demander1mL*10mM (DMSO)75,00€PD 168568 dihydrochloride
CAS :PD 168568 dihydrochloride (PD 168568 (dihydrochloride)) is an orally active and selective antagonist of D4 dopamine receptor(Ki of 8.8 nM).Formule :C22H29Cl2N3ODegré de pureté :99.27%Couleur et forme :SolidMasse moléculaire :422.39Ref: TM-T12383
5mg48,00€10mg58,00€25mg117,00€50mg170,00€100mg248,00€200mg348,00€1mL*10mM (DMSO)60,00€Pimethixene maleate
CAS :Pimethixene maleate (Pimetixene maleate) is a 5-HT2B receptor antagonist with sedative activity that can be used to study dry cough in children.Formule :C23H23NO4SDegré de pureté :100%Couleur et forme :SolidMasse moléculaire :409.5SCH-23390 hydrochloride
CAS :SCH-23390 hydrochloride (R-(+)-SCH23390 hydrochloride) is an effective dopamine receptor antagonist, and for the D1(Ki=0.2 nM) and D5(Ki=0.3 nM).Formule :C17H19Cl2NODegré de pureté :98% - 99.51%Couleur et forme :SolidMasse moléculaire :324.24Ref: TM-T4369
1mg39,00€2mg50,00€5mg78,00€10mg97,00€25mg195,00€50mg369,00€100mg550,00€1mL*10mM (DMSO)78,00€Ordopidine
CAS :Ordopidine (ACR325) is a dopaminergic stabilizer that suppresses psychostimulant-induced hyperactivity disorder and stimulates behavior during inactivity.Formule :C14H20FNO2SDegré de pureté :99.52%Couleur et forme :SolidMasse moléculaire :285.38Spiroxatrine
CAS :Spiroxatrine (R 5188) is a 5-HT1α and α2-adrenergic dual antagonist with sedative activity for the study of diseases related to the cardiovascular system.Formule :C22H25N3O3Degré de pureté :99.83%Couleur et forme :SolidMasse moléculaire :379.45
