Signalisation du cytosquelette
Les inhibiteurs de la signalisation du cytosquelette sont des composés qui perturbent les voies de signalisation régulant le cytosquelette, essentiel pour la forme, la motilité, la division des cellules et le transport intracellulaire. Ces inhibiteurs sont utilisés pour étudier la dynamique des protéines du cytosquelette, telles que l'actine et la tubuline, et leur rôle dans des processus comme la migration cellulaire, l'adhésion et la métastase du cancer. Les inhibiteurs de la signalisation du cytosquelette sont précieux dans la recherche en biologie cellulaire, en cancérologie et en neurobiologie. Chez CymitQuimica, nous offrons une gamme complète d'inhibiteurs de la signalisation du cytosquelette de haute qualité pour soutenir vos recherches dans ces domaines.
Produits appartenant à la catégorie "Signalisation du cytosquelette"
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PKCθ pseudosubstrate peptide inhibitor,myristoylated
Myristoylated PKCθ pseudosubstrate peptide inhibitor is a synthetic peptide utilized to investigate the mechanism of action of protein kinase C theta (PKCθ) [1Formule :C105H184N36O21SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :2318.88Miransertib
CAS :Miransertib (ARQ-092) is an orally bioavailable, selective, and potent allosteric Akt inhibitor.Formule :C27H24N6Degré de pureté :98.83% - ≥95%Couleur et forme :SolidMasse moléculaire :432.52Ref: TM-T3467
1mg52,00€5mg97,00€10mg169,00€25mg344,00€50mg567,00€100mg908,00€500mg1.795,00€1mL*10mM (DMSO)114,00€Defactinib hydrochloride
CAS :Defactinib hydrochloride (PF 04554878 hydrochloride) is a novel inhibitor of FAK.Formule :C20H22ClF3N8O3SDegré de pureté :98.06% - 98.78%Couleur et forme :SolidMasse moléculaire :546.95Midostaurin
CAS :PKC412(Midostaurin (PKC412); CGP41231; CGP41251) is a broad spectrum protein kinase inhibitor.Formule :C35H30N4O4Degré de pureté :100% - 99.47%Couleur et forme :SolidMasse moléculaire :570.64Ref: TM-T3211
1mg51,00€5mg88,00€10mg126,00€25mg216,00€50mg328,00€100mg487,00€500mg1.093,00€1mL*10mM (DMSO)96,00€LY3372689
CAS :LY3372689 (Formulaic Ia) is an orally active O-GlcNAcase (OGA) enzyme inhibitor for tau protein-based disorders including Alzheimer's disease.Formule :C16H22FN5O3SDegré de pureté :99.27% - 99.45%Couleur et forme :SolidMasse moléculaire :383.44Ref: TM-T61661
1mg99,00€5mg235,00€10mg354,00€25mg635,00€50mg935,00€100mg1.415,00€1mL*10mM (DMSO)259,00€Multi-kinase inhibitor 1
CAS :Multi-kinase inhibitor 1 (Multi-kinase inhibitor I) is a Multi-kinase inhibitor.Formule :C20H17F3N4O3Degré de pureté :99.34%Couleur et forme :SolidMasse moléculaire :418.37FRAX597
CAS :FRAX597 is an effective, ATP-competitive inhibitor of group I PAKs, and for PAK1(IC50=8 nM), PAK2(IC50=13 nM), and PAK3 (IC50=19 nM).Formule :C29H28ClN7OSDegré de pureté :97.34% - 99.85%Couleur et forme :SolidMasse moléculaire :558.1Ansamitocin P 3'
CAS :Ansamitocin P 3' (Maytansinol butyrate) is an antibody-drug conjugate cytotoxin with antitumor activity.Formule :C32H43ClN2O9Degré de pureté :98.16% - 99.16%Couleur et forme :SolidMasse moléculaire :635.14Ref: TM-T1910
2mg34,00€5mg50,00€10mg84,00€25mg145,00€50mg229,00€100mg340,00€200mg472,00€1mL*10mM (DMSO)70,00€Ifebemtinib
CAS :Ifebemtinib (BI-853520) is an adhesion plaque kinase inhibitor with anti-tumour activity for the study of breast cancer.Formule :C28H28F4N6O4Degré de pureté :98.07% - 99.82%Couleur et forme :SolidMasse moléculaire :588.55Ionomycin calcium
CAS :Ionomycin calcium (SQ23377 calcium) is an effective and selective calcium ionophore, exhibiting high specificity for calcium ions. Cost-effective and quality-assured.Formule :C41H70CaO9Degré de pureté :98% - 98.11%Couleur et forme :SolidMasse moléculaire :747.07NAMI-A
CAS :NAMI-A is a ruthenium-based compound with selective activity against tumor metastasis.NAMI-A inhibits cancer cell adhesion and migration.Formule :C8H15Cl4N4ORuSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :458.18Ipfencarbazone
CAS :Ipfencarbazone herbicide agent, is a substance being developed for the control of weeds such as watergrass in rice.Formule :C18H14Cl2F2N4O2Couleur et forme :SolidMasse moléculaire :427.23Dynapyrazole A
CAS :Dynapyrazole A inhibits dynein 1 and 2 (IC50s: 2.3, 2.6 μM) and Hedgehog signaling (IC50: 1.9 μM).Formule :C20H12ClIN4ODegré de pureté :98.01%Couleur et forme :SolidMasse moléculaire :486.69RWJ 50271
CAS :RWJ 50271 inhibits LFA-1/ICAM-1 interaction with IC50 5.0 μM in HL60 cells.Formule :C18H17F3N4O2SDegré de pureté :99.09%Couleur et forme :SolidMasse moléculaire :410.41Ref: TM-T12783
1mg127,00€5mg311,00€10mg472,00€25mg747,00€50mg1.017,00€100mg1.311,00€200mg1.786,00€1mL*10mM (DMSO)344,00€AMP-945
CAS :AMP-945 is a proprietary focal adhesion kinase (FAK) inhibitor.Formule :C28H32F3N5O2Degré de pureté :99.60%Couleur et forme :SolidMasse moléculaire :527.58Ref: TM-T9576
1mg97,00€5mg188,00€10mg311,00€25mg533,00€50mg755,00€100mg1.035,00€1mL*10mM (DMSO)254,00€Etrolizumab
CAS :MEDI-578 is a CHO-expressed humanized monoclonal antibody targeting NGF/bNGF for the study of neurological and immune system disorders.Degré de pureté :95% - 95%Couleur et forme :LiquidAdhesamine diTFA
CAS :Adhesamine diTFA, a dumbbell-shaped molecule, activates the MAPK/FAK pathway. It promotes adhesion and growth in mammalian cells and accelerates differentiation and enhances the survival rate of primary cultured mouse hippocampal neurons.Formule :C28H32Cl2F6N8O6S2Couleur et forme :SolidMasse moléculaire :825.63BX-2819
CAS :BX-2819 is an Hsp90 inhibitor that exhibits potent antiproliferative activity with an IC50 of 41 nM .Formule :C21H24N4O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :428.51αvβ1 integrin-IN-1 TFA (1689540-62-2 free base)
αvβ1 integrin-IN-1 TFA is an effective and selective αvβ1 integrin inhibitor (IC50: 0.63 nM).Formule :C28H35F3N6O8SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :672.67Hydroxy-Dynasore
CAS :Hydroxy-Dynasore (Dyngo-4a) , a effective dynamin inhibitor, inhibits withDynI (brain), DynI (rec), and DynII (rec) of IC50 of 0.38 μM, 1.1 μM, and 2.3 μM,Formule :C18H14N2O5Degré de pureté :100% - 97.60%Couleur et forme :SolidMasse moléculaire :338.31Ref: TM-T6822
5mg50,00€10mg84,00€25mg137,00€50mg221,00€100mg329,00€200mg490,00€500mg783,00€1mL*10mM (DMSO)55,00€αvβ6-IN-1
αvβ6-IN-1 (compound 28) is an effective orally active inhibitor of αvβ6 integrin (αvβ6integrin), with a pIC50 value of 8.1. This compound shows potential for research in idiopathic pulmonary fibrosis.Formule :C25H32F2N4O3Couleur et forme :SolidMasse moléculaire :474.5416-38-Thymosin β4 (cattle) (TFA)
Thymosin β4 (cattle) TFA is a high-affinity activator of MLCK that operates independently of Ca2+ [1].Formule :C120H205F3N32O43Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :2841.1K858 (Racemic)
CAS :K858 Racemic (K858) is a selective mitotic kinesin Eg5 inhibitor which acts in an ATP-noncompetitive manner.Formule :C13H15N3O2SDegré de pureté :100%Couleur et forme :SolidMasse moléculaire :277.34AZ13705339
CAS :AZ13705339 is an effective inhibitor of PAK1 with an IC50 of 0.33 nM and a Kd of 0.28 nM.Formule :C33H36FN7O3SDegré de pureté :98.57%Couleur et forme :SolidMasse moléculaire :629.75FAK-IN-7
CAS :FAK-IN-7 has potential antiproliferative activity and is a FAK inhibitor.Formule :C16H13N3OSDegré de pureté :98.2%Couleur et forme :SolidMasse moléculaire :295.36AJH-836
CAS :AJH-836 is a compound that activates Munc13-1 and PKC ε/α, demonstrating a dissociation constant (Kd) of 4.5 nM for PKCα, and facilitates the translocation ofFormule :C22H38O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :382.5310-Deacetyltaxol
CAS :10-Deacetyltaxol (10-DAT) is extracted from Taxus brevifolia barks.Formule :C45H49NO13Degré de pureté :94.63% - 99.93%Couleur et forme :SolidMasse moléculaire :811.87Tadocizumab
CAS :Tadocizumab (C4G1) is a humanized monoclonal antibody targeting integrin αIIbβ3 with antiplatelet and antithrombotic effects.Couleur et forme :LiquidKNK437
CAS :KNK437 (Heat Shock Protein Inhibitor I), a pan-HSP inhibitor, suppresses the synthesis of inducible HSPs(HSP105, HSP72, and HSP40).Formule :C13H11NO4Degré de pureté :98.90%Couleur et forme :SolidMasse moléculaire :245.23PKC-IN-1
CAS :PKC-IN-1 is an ATP-competitive and reversible conventional PKC enzymes inhibitor (PKCα, PKCβI, PKCβII, PKCθ, PKCγ, PKC mu and PKCε with IC50s of 2.3, 8.1, 7.6,Formule :C25H37FN8O2Degré de pureté :98% - 98.79%Couleur et forme :SolidMasse moléculaire :500.61Gamitrinib TPP
CAS :Gamitrinib TPP targets mitochondrial HSP90, inhibiting cancer, and blocks mitochondrial matrix.Formule :C52H65N3O8PDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :891.078API-1
CAS :API-1 (NSC-177223) is a potent inhibitor of Akt. It induces GSK3-dependent, β-TrCP- and FBXW7-mediated Mcl-1 degradation, resulting in induction of apoptosis .Formule :C13H15N5O6Degré de pureté :99.07%Couleur et forme :SolidMasse moléculaire :337.29Ref: TM-T8969
1mg59,00€5mg125,00€10mg207,00€25mg376,00€50mg562,00€100mg787,00€200mg1.035,00€1mL*10mM (DMSO)133,00€AKT-IN-1
CAS :AKT-IN-1 (AZD-26) is an allosteric AKT inhibitor (IC50: 1.04 μM).Formule :C22H21N3ODegré de pureté :98.63%Couleur et forme :SolidMasse moléculaire :343.42Ref: TM-T4489
1mg113,00€2mg158,00€5mg235,00€10mg400,00€25mg652,00€50mg909,00€100mg1.225,00€1mL*10mM (DMSO)188,00€HSP70/SIRT2-IN-2
CAS :HSP70/SIRT2-IN-2 (Compounds 1a), a dual inhibitor of SIRT2 and HSP70, exhibits an IC50 of 45.1±5.0 μM against SIRT2 and demonstrates antitumor activity [1].Formule :C17H13N3S3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :355.5LXH254
CAS :LXH254 is a B/C RAF inhibitor with IC50 values of 0.2 nM and 0.07 nM for inhibiting BRAF and CRAF.Cost-effective and quality-assured.Formule :C25H25F3N4O4Degré de pureté :98.3% - 99.92%Couleur et forme :SolidMasse moléculaire :502.49Ref: TM-T11898
1mg52,00€5mg122,00€10mg185,00€25mg363,00€50mg567,00€100mg690,00€200mg948,00€500mg1.444,00€1mL*10mM (DMSO)135,00€Debio 0932
CAS :Debio 0932 (CUDC-305) is a Hsp9 inhibitor, apoptosis, and has the advantage of being orally available and cross the BBB for cancers NSCLC and neuroblastoma.Formule :C22H30N6O2SDegré de pureté :98.98%Couleur et forme :SolidMasse moléculaire :442.58AT9283
CAS :AT9283 (J-504568) is an effective multi-targeted inhibitor of JAK2(IC50=1.2 nM) and JAK3(IC50=1.1 nM), Aurora A, Aurora B and Abl(T315I).Formule :C19H23N7O2Degré de pureté :99.83% - 99.98%Couleur et forme :SolidMasse moléculaire :381.43Ref: TM-T3068
1mg47,00€2mg60,00€5mg95,00€10mg170,00€25mg299,00€50mg499,00€100mg723,00€1mL*10mM (DMSO)97,00€Bisindolylmaleimide III
CAS :Bisindolylmaleimide III is a potent and selective inhibitor of protein kinase C (PKC).Bisindolylmaleimide III selectively interacts with PKCα or ribosomal S6Formule :C23H20N4O2Degré de pureté :98.6%Couleur et forme :SolidMasse moléculaire :384.43Pifithrin-μ
CAS :Pifithrin-μ (NSC-303580) is an inhibitor of p53 and HSP70, with neuroprotective and antitumor activity.Formule :C8H7NO2SDegré de pureté :99.33% - 99.79%Couleur et forme :SolidMasse moléculaire :181.21KP-23172
CAS :KP-23172 is a inhibitor of PI3-K/Akt pathway.Formule :C10H4N6ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :224.18ML346
CAS :ML346 is a novel activator of Hsp70.Formule :C14H12N2O4Degré de pureté :99.25% - 99.29%Couleur et forme :SolidMasse moléculaire :272.26Ref: TM-T3594
1mg40,00€2mg52,00€5mg85,00€10mg115,00€25mg172,00€50mg274,00€100mg427,00€500mg938,00€1mL*10mM (DMSO)85,00€Degrasyn
CAS :Degrasyn (WP1130) inhibits DUBs (USP5, UCH-L1, USP9x, USP14, UCH37) and Bcr/Abl without affecting the 20S proteasome.Formule :C19H18BrN3ODegré de pureté :98.32% - 99.98%Couleur et forme :SolidMasse moléculaire :384.27Ref: TM-T6300
2mg44,00€5mg64,00€10mg97,00€25mg198,00€50mg340,00€100mg532,00€200mg747,00€1mL*10mM (DMSO)69,00€Phorbol 12,13-dibutyrate
CAS :Phorbol 12,13-dibutyrate (Phorbol dibutyrate) is a PKC activator that induces contraction of isolated rabbit vascular smooth muscle.Formule :C28H40O8Degré de pureté :100% - 99.32%Couleur et forme :SolidMasse moléculaire :504.61Ref: TM-T16526
1mg62,00€5mg169,00€10mg283,00€25mg557,00€50mg795,00€100mg1.074,00€1mL*10mM (DMSO)180,00€Akt3 degrader 1
CAS :Akt3 degrader 1 counters Osimertinib resistance in NSCLC, inhibits cell growth, and reduces mouse tumors.Formule :C53H72N8O4Degré de pureté :98.18% - 99.14%Couleur et forme :SolidMasse moléculaire :885.19VTX-27
CAS :VTX-27 is a selective inhibitor of protein kinase C θ (PKC θ) (Kis: 0.08 nM and 16 nM for PKC θ and PKC δ).Formule :C20H24ClFN6ODegré de pureté :99.49%Couleur et forme :SolidMasse moléculaire :418.9Ref: TM-T13314
1mg93,00€2mg125,00€5mg244,00€10mg364,00€25mg562,00€50mg780,00€100mg1.035,00€1mL*10mM (DMSO)225,00€Ruboxistaurin hydrochloride
CAS :Ruboxistaurin HCl (LY 333531) selectively inhibits PKCβI/II with IC50 of 4.7/5.9 nM; much less effective on other PKC types and ATP-kinases.Formule :C28H28N4O3·HClDegré de pureté :98.44% - 99.22%Couleur et forme :SolidMasse moléculaire :505.01Ref: TM-T3689
1mg71,00€2mg93,00€5mg157,00€10mg256,00€25mg513,00€50mg740,00€100mg1.035,00€500mg2.072,00€1mL*10mM (DMSO)202,00€Imatinib
CAS :Imatinib (STI571) is a multi-targeted receptor tyrosine kinase inhibitor that selectively inhibits the kinase activities of BCR/ABL, v-Abl, PDGFR, and c-kitFormule :C29H31N7ODegré de pureté :100% - 99.94%Couleur et forme :Off White PowderMasse moléculaire :493.6Tetradecyltrimethylammonium bromide
CAS :Tetradecyltrimethylammonium bromide (MitMAB) is a Dynamin GTPase activity inhibitor and a cationic surfactant with asymmetrical structure.Formule :C17H38BrNDegré de pureté :100%Couleur et forme :SolidMasse moléculaire :336.39K-252b
CAS :K-252b, an indolocarbazole derived from the actinomycete Nocardiopsis, functions as a protein kinase C (PKC) inhibitor.Formule :C26H19N3O5Degré de pureté :98%Couleur et forme :Ready-To-Use SolutionMasse moléculaire :453.45Larazotide acetate
CAS :Larazotide acetate is a synthetic peptide. It functions as a tight junction regulator and reverses leaky junctions to their normally closed state.Formule :C34H59N9O12Degré de pureté :95.53%Couleur et forme :SolidMasse moléculaire :785.89para-Nitroblebbistatin
CAS :para-Nitroblebbistatin is a non-cytotoxic, non-fluorescent, photostable, and specific inhibitor of myosin II.Cost-effective and quality-assured.Formule :C18H15N3O4Degré de pureté :100% - 99.92%Couleur et forme :SolidMasse moléculaire :337.33Ref: TM-T12360
1mg87,00€5mg212,00€10mg316,00€25mg512,00€50mg695,00€100mg940,00€200mg1.264,00€1mL*10mM (DMSO)215,00€Chromeceptin
CAS :Chromeceptin is an inhibitor of the IGF signaling pathway, decreases the numbers of tumorsphere, and inhibits the AKT/mTOR pathway.Formule :C19H16F3N3ODegré de pureté :99.72%Couleur et forme :SoildMasse moléculaire :359.35Ref: TM-T60055
5mg50,00€10mg74,00€25mg140,00€50mg197,00€100mg306,00€200mg442,00€1mL*10mM (DMSO)51,00€PU-H71
CAS :PU-H71 is an effective selective HSP90 inhibitor with an IC50 of 51 nM.Formule :C18H21IN6O2SDegré de pureté :98.31%Couleur et forme :SolidMasse moléculaire :512.37Delcasertib
CAS :Delcasertib (KAI-9803) is a potent and selective inhibitor of δ-protein kinase C (δPKC).Formule :C120H199N45O34S2Degré de pureté :99.96%Couleur et forme :SolidMasse moléculaire :2880.28Ref: TM-T11740
1mg202,00€5mg512,00€10mg740,00€25mg1.121,00€50mg1.539,00€100mg2.072,00€1mL*10mM (DMSO)1.691,00€1-Oleoyl-2-acetyl-sn-glycerol
CAS :1-Oleoyl-2-acetyl-sn-glycerol (1-oleoyl-2-acetyl-glycerol) is a PKC activator that induces superoxide production.Formule :C23H42O5Couleur et forme :SolidMasse moléculaire :398.58Nilotinib hydrochloride
CAS :Nilotinib HCl (AMN-107 HCl), an oral Bcr-Abl inhibitor, targets neuroinflammation, cognitive issues, and chronic myelogenous leukemia.Formule :C28H23ClF3N7ODegré de pureté :100%Couleur et forme :SolidMasse moléculaire :565.98Hispidin
CAS :Hispidin is a polyphenol originally, including antioxidant, anti-inflammatory, and cytoprotective propertiesFormule :C13H10O5Degré de pureté :98.27%Couleur et forme :White Crystalline PowderMasse moléculaire :246.22Ref: TM-T7792
1mg88,00€5mg187,00€10mg298,00€25mg533,00€50mg747,00€100mg1.017,00€1mL*10mM (DMSO)207,00€SB-743921 hydrochloride
CAS :SB-743921 hydrochloride (SB743921 HCl) is an effective inhibitor of kinesin spindle protein, KSP, (Ki =0.1 nM).Formule :C31H34Cl2N2O3Degré de pureté :95.58% - 99.70%Couleur et forme :SolidMasse moléculaire :553.52Ref: TM-T2255
1mg42,00€5mg106,00€10mg163,00€25mg278,00€50mg429,00€100mg657,00€500mg1.501,00€1mL*10mM (DMSO)130,00€PPY A
CAS :PPY A is a potent inhibitor of T315l mutant and wild-type Abl kinase and inhibits the growth of Bcr-Abl T315l mutant or wild-type Bcr-Abl gene-transformed cellsFormule :C22H20N4O2Degré de pureté :98.77%Couleur et forme :SolidMasse moléculaire :372.42ILK-IN-2
CAS :ILK-IN-2 (OSU-T315) is a novel potent, orally active ILK (integrin-linked kinase) inhibitor with IC50 of 0.6 μM.Formule :C30H30F3N5ODegré de pureté :99.30%Couleur et forme :SolidMasse moléculaire :533.59Ref: TM-T5488
1mg48,00€5mg97,00€10mg128,00€25mg162,00€50mg192,00€100mg281,00€200mg408,00€1mL*10mM (DMSO)137,00€Rosabulin
CAS :v Rosabulin (STA 5312) is an orally active microtubule inhibitor with potency.Formule :C22H16N4O2SDegré de pureté :98.06%Couleur et forme :SolidMasse moléculaire :400.45Ref: TM-T16788
1mg97,00€5mg243,00€10mg364,00€25mg658,00€50mg938,00€100mg1.415,00€1mL*10mM (DMSO)265,00€Arg-Gly-Asp-Ser acetate
Arg-Gly-Asp-Ser acetate targets integrin, binding pro-caspase-8, -9, -3, but not -1; inhibits receptor function.Formule :C17H31N7O10Degré de pureté :98.14%Couleur et forme :SolidMasse moléculaire :493.47Hsp90-IN-34
CAS :Hsp90-IN-34 (compound HAM-1) is a chemical inhibitor that targets the Aha1-Hsp90 chaperone complex with high affinity (KDapp=23.5 µM). It modulates the ATPase activity of Hsp90 by affecting the interaction between Hsp90 and Aha1.Formule :C22H14F2N6OCouleur et forme :SolidMasse moléculaire :416.38Mivobulin
CAS :Mivobulin is an inhibitor of tubulin .Formule :C17H19N5O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :325.37FPA-124
CAS :FPA-124 is a cell-permeable copper complex that acts as a selective Akt (protein kinase B) inhibitor to induce apoptosis in a variety of cancer cell lines.Formule :C11H9Cl2CuN3O2SDegré de pureté :95.04%Couleur et forme :SolidMasse moléculaire :381.73ZLY06
CAS :ZLY06 is a dual agonist of peroxisome proliferator-activated receptors (PPAR) δ and γ with oral activity (PPAR δ: EC50=341 nM; PPARγ: EC50=237 nM). It mediates the upregulation of CD36 and induces hepatic lipid accumulation by inhibiting the phosphorylation of AKT1. Moreover, ZLY06 significantly improves glucose and lipid metabolism without increasing body weight, primarily by enhancing the β-oxidation of fatty acids and reducing hepatic lipid synthesis, thereby alleviating fatty liver disease.Formule :C25H26O6Couleur et forme :SolidMasse moléculaire :422.47ATN-161 trifluoroacetate salt
CAS :ATN-161 TFA salt, a new integrin α5β1 inhibitor, curbs angiogenesis, liver metastases growth, enhances survival in mice.Formule :C25H36F3N9O10SDegré de pureté :98% - 99.98%Couleur et forme :SolidMasse moléculaire :711.67PND-1186
CAS :PND-1186 (VS-4718) is a reversible and specific FAK inhibitor (IC50: 1.5 nM).Formule :C25H26F3N5O3Degré de pureté :99.14% - 99.75%Couleur et forme :SolidMasse moléculaire :501.5Catumaxomab
CAS :Catumaxomab is a rat-mouse hybrid lgG2 monoclonal and bispecific antibody that binds to the antigens CD3 and EpCAM for malignant ascites in cancer patients.Degré de pureté :95%Couleur et forme :LiquidCK-869
CAS :CK-869 is an Actin-Related Protein 2/3 (ARP2/3) complex inhibitor(IC50 of 7 μM),and is useful tools for the investigation of the Arp2/3 complex.Formule :C17H16BrNO3SDegré de pureté :99.85%Couleur et forme :SolidMasse moléculaire :394.28Zelavespib hydrochloride
Zelavespib (PU-H71) hydrochloride is a potent inhibitor of Hsp90, exhibiting an IC50 value of 51 nM in MDA-MB-468 cells.Degré de pureté :98%Couleur et forme :Odour SolidSC79
CAS :SC79 is an AKT agonist with specificity and blood-brain barrier permeability.Formule :C17H17ClN2O5Degré de pureté :98% - 99.93%Couleur et forme :SolidMasse moléculaire :364.78β-glycosidase-IN-1
CAS :β-glycosidase-IN-1 is a piperidine derivative, and is an inhibitor of β-glycosidase. It has hypoglycemic activity.Formule :C13H23NO5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :273.33A-3 hydrochloride
CAS :A-3 hydrochloride: potent, reversible kinase antagonist; permeable; inhibits PKC, CKI, PKA, CKII, MLCK; Ki: 4.3-80 μM.Formule :C12H14Cl2N2O2SDegré de pureté :99.32%Couleur et forme :SolidMasse moléculaire :321.22Ref: TM-T14069
1mg35,00€5mg66,00€10mg96,00€25mg170,00€50mg274,00€100mg439,00€500mg938,00€1mL*10mM (DMSO)90,00€(8R)-8-Hydroxyepoxyboetirane A
(8R)-8-Hydroxyepoxyboetirane A is a neuroactivating compound that interacts with PKCδ-C1B. This compound binds into the PKC enzyme pocket through hydrogen bonds with glycine-253, leucine-251, and threonine-242. It induces the release of NRG1 and promotes the differentiation of neural stem cells into neurons. (8R)-8-Hydroxyepoxyboetirane A holds potential for research into nervous system disorders.Couleur et forme :Odour SolidTASP0415914
CAS :TASP0415914 is an orally potent inhibitor of phosphoinositide 3-kinase γ (PI3Kγ). TFormule :C13H17N5O3SDegré de pureté :98.14%Couleur et forme :SolidMasse moléculaire :323.37Ref: TM-T7879
1mg55,00€5mg117,00€10mg187,00€25mg315,00€50mg449,00€100mg620,00€200mg835,00€1mL*10mM (DMSO)134,00€Orbofiban TFA
CAS :Orbofiban TFA is an orally active GPIIb/IIIa platelet receptor antagonist with inhibitory effects on platelet aggregation for the study of unstable coronaryFormule :C19H24F3N5O6Degré de pureté :97.45% - 98.43%Couleur et forme :SolidMasse moléculaire :475.42HSP27 inhibitor J2
CAS :HSP27 inhibitor J2 (J2) (J2) is a HSP27 inhibitor, inhibits a production of HSP27 giant polymers, thereby having an effect of inhibiting a chaperone function ofFormule :C13H12O4SDegré de pureté :99.51%Couleur et forme :SolidMasse moléculaire :264.3Ref: TM-T7265
1mg130,00€2mg185,00€5mg311,00€10mg472,00€25mg753,00€50mg1.064,00€100mg1.415,00€1mL*10mM (DMSO)455,00€Firategrast
CAS :Firategrast (SB 683699) is an orally active and specific α4β1/α4β7 integrin antagonist.Firategrast reduces the transport of lymphocytes into the central nervousFormule :C27H27F2NO6Degré de pureté :99.16%Couleur et forme :SolidMasse moléculaire :499.5Ref: TM-TQ0291
1mg47,00€5mg87,00€10mg140,00€25mg283,00€50mg464,00€100mg747,00€200mg1.017,00€1mL*10mM (DMSO)97,00€Vevorisertib trihydrochloride
CAS :Vevorisertib trihydrochloride (ARQ 751 trihydrochloride) is ainhibitor of pan-AKT and AKT1-E17K mutations, inhibiting AKT1, AKT2 and AKT3.Formule :C35H41Cl3N8ODegré de pureté :98.28%Couleur et forme :SolidMasse moléculaire :696.12Ref: TM-T38846
1mg70,00€5mg149,00€10mg230,00€25mg393,00€50mg552,00€100mg740,00€200mg1.130,00€1mL*10mM (DMSO)212,00€Teprenone
CAS :Teprenone (Geranylgeranylacetone) is a anti-ulcer drug, and works as an inducer of heat shock proteins (HSPs).Formule :C23H38ODegré de pureté :99.76% - 99.96%Couleur et forme :SolidMasse moléculaire :330.55FAK-IN-14
CAS :FAK-IN-14 is a FAK inhibitor that induces apoptosis and cell cycle arrest. FAK-IN-14 has a more significant inhibitory effect on FAK, FGFR1 and Pyk2.Formule :C21H24BrN7OSDegré de pureté :99.7%Couleur et forme :SoildMasse moléculaire :502.43BNC105
CAS :BNC105 is a tubulin polymerization inhibitor. It has potent antiproliferative and tumor vascular disrupting properties.Formule :C20H20O7Degré de pureté :96.57%Couleur et forme :SolidMasse moléculaire :372.37Ref: TM-T14694
1mg84,00€5mg160,00€10mg226,00€25mg371,00€50mg520,00€100mg702,00€200mg944,00€1mL*10mM (DMSO)170,00€Teclistamab
CAS :Teclistamab(JNJ-64007957) is a human bispecific monoclonal antibody targeting the CD3 receptor on t-cells and the BCMA for relapsed and refractory multiple myeloma.Degré de pureté :95%Couleur et forme :LiquidPentachloropseudilin
CAS :Pentachloropseudilin inhibits Myosin-1 and speeds up TGF-β receptor turnover, suppressing TGF-β activity.Formule :C10H4Cl5NODegré de pureté :98.14%Couleur et forme :SolidMasse moléculaire :331.41PF-562271
CAS :PF-562271 is an effective ATP-competitive, reversible inhibitor of FAK(IC50=1.5 nM) and Pyk2 kinase(IC50=13 nM).Formule :C21H20F3N7O3SDegré de pureté :100% - 97.65%Couleur et forme :SolidMasse moléculaire :507.49Ref: TM-T2465
1mg59,00€5mg127,00€10mg159,00€25mg240,00€50mg378,00€100mg567,00€200mg793,00€1mL*10mM (DMSO)140,00€Akt1 and Akt2-IN-1
CAS :Akt1 and Akt2-IN-1 is an allosteric inhibitor of Akt1 (IC50=3.5 nM) and Akt2 (IC50=42 nM). It has potent and balanced activity.Formule :C33H29N7OCouleur et forme :SolidMasse moléculaire :539.63cSRC/BCR-ABL-IN-1
cSRC/BCR-ABL-IN-1 (compound 21b) is a potent inhibitor of Bcr-Abl and C-Src, with IC50 values of 56.2 nM and 101 nM, respectively. It exhibits cytotoxicity.Formule :C29H31Cl2N5O4Masse moléculaire :584.494ε-V1-2, Cys-conjugated
Epsilon-V1-2, a Cys-conjugated, is a biologically active peptide known as the εPKC-specific inhibitor.Formule :C40H70N10O14SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :947.11Miltefosine
CAS :Miltefosine (HePC), effective oral drug for both visceral and cutaneous leishmaniasis, in clinical trials worldwide.Formule :C21H46NO4PDegré de pureté :98% - 99.87%Couleur et forme :White To Off-White PowderMasse moléculaire :407.57SMTIN-T140
CAS :SMTIN-T140: strong TRAP1 inhibitor, IC50=1.646μM, anticancer; disrupts mitochondria, boosts ROS, activates AMPK, shrinks PC3 tumors, no in vivo toxicity.Formule :C36H34BrClFN5OPDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :718.02HA-100
CAS :HA-100 is an inhibitor of protein kinaseFormule :C13H15N3O2SDegré de pureté :99.44%Couleur et forme :Pale Yellow Crystalline SolidMasse moléculaire :277.3420-HETE
CAS :20-HETE is a CYP450 product, vasoconstrictor, modulates K+ channels, affects NADPH, ROS, NF-κB, NO synthase, and cell apoptosis/proliferation.Formule :C20H32O3Degré de pureté :99.79%Couleur et forme :SolidMasse moléculaire :320.47Ref: TM-T14021
1mg (312.04μM*10mL in Ethanol)1.139,00€5mg (312.04μM*50mL in Ethanol)2.327,00€100μg (312.04μM*1mL in Ethanol)474,00€PKCiota-IN-2
CAS :PKCiota-IN-2 selectively inhibits PKC-ι (IC50=2.8nM) and also blocks PKC-α, ε (IC50s=71nM, 350nM).Formule :C24H21N5ODegré de pureté :99.74%Couleur et forme :SolidMasse moléculaire :395.46Ref: TM-T9863
1mg115,00€2mg172,00€5mg255,00€10mg375,00€25mg562,00€50mg792,00€100mg1.064,00€1mL*10mM (DMSO)279,00€(E)-Akt inhibitor-IV
CAS :(E)-Akt inhibitor-IV ((E)-AKTIV) ((E)-AKTIV) is an inhibitor of PI3K-Akt.Formule :C31H29IN4SDegré de pureté :99.01% - 99.74%Couleur et forme :SolidMasse moléculaire :616.56Ref: TM-T9393
1mg55,00€5mg116,00€10mg180,00€25mg338,00€50mg469,00€100mg655,00€200mg924,00€1mL*10mM (DMSO)157,00€Eupalinolide A
CAS :Eupalinolide B is a natural product ,and demonstrates potent cytotoxicity against A-549, BGC-823, SMMC-7721, and HL-60 tumour cell lines.Formule :C24H30O9Degré de pureté :98.18% - 99.22%Couleur et forme :SolidMasse moléculaire :462.49Taurochenodeoxycholic acid sodium
CAS :Sodium taurochenodeoxycholate: induces apoptosis, anti-inflammatory, boosts insulin, stimulates α2-cells, increases [Ca(2+)](c).Formule :C26H44NNaO6SDegré de pureté :98.23% - 99.45%Couleur et forme :White To Off-White PowderMasse moléculaire :521.68Arimoclomol maleate
CAS :Arimoclomol maleate (BRX-220) (BRX-220) is a heat shock protein (HSP) co-inducer.Formule :C18H24ClN3O7Degré de pureté :99.9% - 99.98%Couleur et forme :SolidMasse moléculaire :429.85Ombrabulin hydrochloride
CAS :Ombrabulin hydrochloride is a synthetic, selective CA-4 phosphate ester or derivative of Ombrabulin to disrupt the tubulin cytoskeleton of endothelial cells andFormule :C21H27ClN2O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :438.9Roslin 2 bromide
CAS :Roslin 2 bromide (Benzylhexamethylenetetramine bromide) is a p53 reactivator that disrupts the binding of FAK and p5.Formule :C13H19BrN4Degré de pureté :97.07%Couleur et forme :SolidMasse moléculaire :311.22
