Signalisation du cytosquelette
Les inhibiteurs de la signalisation du cytosquelette sont des composés qui perturbent les voies de signalisation régulant le cytosquelette, essentiel pour la forme, la motilité, la division des cellules et le transport intracellulaire. Ces inhibiteurs sont utilisés pour étudier la dynamique des protéines du cytosquelette, telles que l'actine et la tubuline, et leur rôle dans des processus comme la migration cellulaire, l'adhésion et la métastase du cancer. Les inhibiteurs de la signalisation du cytosquelette sont précieux dans la recherche en biologie cellulaire, en cancérologie et en neurobiologie. Chez CymitQuimica, nous offrons une gamme complète d'inhibiteurs de la signalisation du cytosquelette de haute qualité pour soutenir vos recherches dans ces domaines.
Produits appartenant à la catégorie "Signalisation du cytosquelette"
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Aβ-IN-1 TFA
Aβ-IN-1 TFA inhibits and reverses different types of protein aggregation.Formule :C37H50F3NO2Degré de pureté :100%Couleur et forme :SoildMasse moléculaire :597.79SNX2112
CAS :SNX2112 (PF 04928473) is an orally active Hsp90 inhibitor, with a Kd of 16 nM.Formule :C23H27F3N4O3Degré de pureté :98.9% - 99.46%Couleur et forme :SolidMasse moléculaire :464.48Ref: TM-T6305
1mg40,00€5mg85,00€10mg127,00€25mg220,00€50mg334,00€100mg477,00€200mg662,00€1mL*10mM (DMSO)87,00€CCT251236
CAS :CCT251236 is an orally available Pirin ligand obtained from a heat shock transcription factor 1 (hsf1) phenotypic screen.Formule :C32H32N4O5Degré de pureté :98.82% - 99.89%Couleur et forme :SolidMasse moléculaire :552.62Ref: TM-T14905
1mg39,00€5mg116,00€10mg221,00€25mg457,00€50mg733,00€100mg1.111,00€200mg1.501,00€1mL*10mM (DMSO)144,00€Protein kinase inhibitor H-7 dihydrochloride
CAS :Protein kinase inhibitor H-7 dihydrochloride(H-7 dihydrochloride) is a potent protein kinase C (PKC) inhibitor.Formule :C14H19Cl2N3O2SDegré de pureté :99.54%Couleur et forme :White Crystalline SolidMasse moléculaire :364.29Entasobulin
CAS :Entasobulin is an inhibitor of β-tubulin polymerization. It has a potential anticancer activity.Formule :C26H18ClN3O2Degré de pureté :98.40%Couleur et forme :SolidMasse moléculaire :439.89Bisindolylmaleimide IV
CAS :Bisindolylmaleimide IV is a protein kinase C (PKC) cell permeable inhibitor( IC50 : 0.10 - 0.55 μM)Formule :C20H13N3O2Degré de pureté :98.83%Couleur et forme :Dark Red SolidMasse moléculaire :327.34Cyclo(-RGDfK)
CAS :Cyclo(-RGDfK) is a selective and potent inhibitor of integrin αvβ3 with an IC50 value of 0.94 nM.Cost-effective and quality-assured.Formule :C27H41N9O7Degré de pureté :100% - 99.83%Couleur et forme :SolidMasse moléculaire :603.67Arg-Gly-Asp-Ser
CAS :Arg-Gly-Asp-Ser (RGDS peptide) is a conserved tetrapeptide sequence found in fibronectin, and the von Willebrand factor.Formule :C15H27N7O8Degré de pureté :98.29%Couleur et forme :SolidMasse moléculaire :433.421,2-Dimyristoyl-sn-glycerol
CAS :1,2-Dimyristoyl-sn-glycerol (1,2-DMG) is able to increase AChE activity by 35-40% at concentrations of 25 micrograms/ml in the parasite S. mansoni..Formule :C31H60O5Degré de pureté :99.49%Couleur et forme :White Powder With LumpsMasse moléculaire :512.81PD180970
CAS :PD180970 is an inhibitor of Bcr-Abl with IC50s of 5 nM, 0.8 nM and 50 nM for the autophosphorylation of p210Bcr-Abl, Src and Kit.Formule :C21H15Cl2FN4ODegré de pureté :98.47%Couleur et forme :SolidMasse moléculaire :429.27Cyclo(Gly-Arg-Gly-Asp-Ser-Pro)
CAS :Cyclo(Gly-Arg-Gly-Asp-Ser-Pro) (c(GRGDSP)) is an RGD-containing inhibitory peptide and a synthetic α5β1 integrin ligand.Formule :C22H35N9O9Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :569.57PF-06651481-00
CAS :PF-06651481-00 (Bosutinib Isomer I) is a Bosutinib analog and a Bcr-Abl inhibitor.Formule :C26H29Cl2N5O3Degré de pureté :97.57%Couleur et forme :SolidMasse moléculaire :530.45SR31527
CAS :SR31527 chloride: potent KIFC1 inhibitor (IC50 6.6 µM), moderately impairs cell viability & colony growth.Formule :C15H14ClN3OSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :319.81PLN-1474
CAS :PLN-1474 is a potent αVβ1 inhibitor with IC50 < 50 nM.Formule :C24H37N3O4Degré de pureté :99.25%Couleur et forme :SoildMasse moléculaire :431.57Ref: TM-T60101
1mg52,00€5mg111,00€10mg180,00€25mg305,00€50mg439,00€100mg612,00€1mL*10mM (DMSO)124,00€Cercosporin
CAS :Cercosporin, produced by the plant pathogen Cercospora kikuchii and the elsinochromes, is a potent photosensitizer with a short activation wavelength. Cercosporin contains perylene quinone structural features essential for PKC activity (IC50: 0.6-1.3 μM).Formule :C29H26O10Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :534.51N-Desmethyl imatinib
CAS :N-Desmethyl imatinib (Imatinib metabolite N-Desmethyl imatinib) is a metabolite of Imatinib, which is a multi-target inhibitor of c-Kit, v-Abl, and PDGFR.Formule :C28H29N7ODegré de pureté :98.60%Couleur et forme :Off-White To Pale-Yellow SolidMasse moléculaire :479.58Ref: TM-T11641
1mg92,00€5mg170,00€10mg319,00€25mg540,00€50mg777,00€100mg1.074,00€1mL*10mM (DMSO)178,00€Geldanamycin
CAS :Geldanamycin, an HSP90 inhibitor (Kd: 1.2 μM), specifically disrupts glucocorticoid receptor (GR)/HSP association.Formule :C29H40N2O9Degré de pureté :98.83% - 99.27%Couleur et forme :Yellow To Orange PowderMasse moléculaire :560.64MAP4343
CAS :Map4343, a 3-methyl ether pregnenolone derivative, binds MAP2, boosts tubulin polymerization, spurs neurite growth, and guards neurons.Formule :C22H34O2Degré de pureté :99.32%Couleur et forme :SolidMasse moléculaire :330.5E7820
CAS :E7820 (ER68203-00) is an angiogenesis inhibitor by suppressing integrin a2 (a cell adhesion molecule expressed on endothelial cells).Formule :C17H12N4O2SDegré de pureté :98.31% - 99.11%Couleur et forme :SolidMasse moléculaire :336.37Ref: TM-T4435
1mg35,00€2mg52,00€5mg69,00€10mg88,00€25mg144,00€50mg210,00€100mg339,00€200mg502,00€1mL*10mM (DMSO)85,00€Iso-H7 dihydrochloride
CAS :Iso-H7 dihydrochloride is a less potent inhibitor of phosphokinase C than H-7.Formule :C14H19Cl2N3O2SDegré de pureté :99.64%Couleur et forme :White Crystalline SolidMasse moléculaire :364.29Ref: TM-T7501
2mg40,00€5mg52,00€10mg90,00€25mg138,00€50mg197,00€100mg293,00€200mg408,00€1mL*10mM (DMSO)66,00€FAK-IN-21
CAS :FAK-IN-21 (compound 9) is a FAK inhibitor with an IC50 value of 37.52 nM. It inhibits cell growth and the phosphorylation of FAK, making it useful for research into diffuse gastric cancer.Formule :C22H22F2N8O3SCouleur et forme :SolidMasse moléculaire :516.52KIF18A-IN-2
CAS :KIF18A-IN-2 is an inhibitor of mitotic kinesin Kif18A with IC50 of 28 nM and can be used in studies about chromosomal instability-associated vulnerabilities.Formule :C25H34N4O5S2Degré de pureté :99.05%Couleur et forme :SolidMasse moléculaire :534.69Ref: TM-T60026
1mg74,00€5mg172,00€10mg245,00€25mg383,00€50mg507,00€100mg672,00€200mg910,00€1mL*10mM (DMSO)202,00€HSP70-IN-1
CAS :HSP70-IN-1 is a heat shock protein (HSP) inhibitor and inhibits the growth of Kasumi-1 cells (IC50: 2.3 μM).Formule :C24H28N6O2SDegré de pureté :100%Couleur et forme :SolidMasse moléculaire :464.58Ref: TM-T3487
1mg96,00€5mg227,00€10mg354,00€25mg620,00€50mg847,00€100mg1.169,00€1mL*10mM (DMSO)230,00€ABT-751
CAS :ABT-751 (E7010) has been investigated for the treatment of Lung Cancer, Non-Small Cell Lung Cancer, and Non-Small-Cell Lung Cancer.Formule :C18H17N3O4SDegré de pureté :98.84% - 99.50%Couleur et forme :SolidMasse moléculaire :371.41AKE-72
CAS :AKE-72 is a Pan-BCR-ABL inhibitor with anti-leukemic activity.AKE-72 inhibits the proliferation of Ba/F3 cells expressing natural BCR-ABL or its T315I mutant.Formule :C30H29F3N6ODegré de pureté :98.3%Couleur et forme :SoildMasse moléculaire :546.59Radotinib
CAS :Radotinib (IY-5511), and sometimes referred to by its investigational name IY5511, is a drug for the treatment of different types of Y, most notablyFormule :C27H21F3N8ODegré de pureté :99.13% - 99.97%Couleur et forme :SolidMasse moléculaire :530.5Col003
CAS :Col003 is a selective and potent inhibitor of Hsp47 and competitively binds to the collagen-binding site on Hsp47 (IC50: 1.8 μM).Formule :C14H11NO4Degré de pureté :98.67% - 99.03%Couleur et forme :SolidMasse moléculaire :257.24Ref: TM-T10860
2mg47,00€5mg70,00€10mg107,00€25mg216,00€50mg350,00€100mg542,00€200mg778,00€500mg1.169,00€1mL*10mM (DMSO)70,00€CGP60474
CAS :CGP60474 is an inhibitor of VEGFR-2 (IC50 = 84 nM) and an inhibitor of ATP-competitive PKC.Formule :C18H18ClN5ODegré de pureté :99.81%Couleur et forme :SolidMasse moléculaire :355.82Ref: TM-T14943
1mg35,00€2mg48,00€5mg74,00€10mg97,00€25mg187,00€50mg331,00€100mg547,00€1mL*10mM (DMSO)82,00€D-64131
CAS :D-64131 is a tubulin polymerization inhibitor with an IC50 value of 0.53 μM.Formule :C16H13NO2Degré de pureté :99.48% - 99.67%Couleur et forme :SolidMasse moléculaire :251.28PKCε (85-92)
CAS :PKCε (85-92) is a biologically active peptide that functions as a specific activator of ε-PKC and induces MARCKS phosphorylation in wild-type cells, but doesFormule :C39H54N10O14Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :886.9Schaftoside
CAS :Schaftoside (APIGENIN-6-GLUCOSIDE-8-ARABINOSIDE) has antioxidant and anticancer activity.Formule :C26H28O14Degré de pureté :100% - 99.32%Couleur et forme :SolidMasse moléculaire :564.49Ref: TM-T3898
1mg42,00€5mg85,00€10mg111,00€25mg210,00€50mg311,00€100mg467,00€200mg653,00€1mL*10mM (DMSO)95,00€FAK-IN-12
FAK-IN-12 (Compound 12S) is a selective FAK inhibitor with an IC50 of 47 nM.Degré de pureté :98%Couleur et forme :Odour SolidTR-14035
CAS :TR-14035 (MDK-1191) is a dual antagonist of α4β7/α4β1 integrins (IC50s: 7/87nM).Formule :C24H21Cl2NO5Degré de pureté :98.98%Couleur et forme :SolidMasse moléculaire :474.33Ref: TM-T5310
1mg52,00€5mg105,00€10mg170,00€25mg298,00€50mg430,00€100mg605,00€200mg815,00€1mL*10mM (DMSO)111,00€Go 6983
CAS :Go 6983 is a pan-PKC inhibitor targeting PKCα, PKCβ, PKCγ, PKCδ, and PKCζ, exhibiting IC50 values of 7 nM, 7 nM, 6 nM, 10 nM, and 60 nM, respectively.Formule :C26H26N4O3Degré de pureté :98.41% - 99.04%Couleur et forme :SolidMasse moléculaire :442.51Ref: TM-T6313
1mg43,00€2mg55,00€5mg84,00€10mg126,00€25mg245,00€50mg388,00€100mg563,00€1mL*10mM (DMSO)88,00€KHS 101
CAS :KHS101 is a novel inhibitor of transforming acidic coiled-coil protein 3 (TACC3). It is a selective inducer of neuronal differentiation.Formule :C18H21N5SDegré de pureté :98.00%Couleur et forme :SolidMasse moléculaire :339.46AKT-IN-18
AKT-IN-18, an Akt inhibitor, demonstrates an IC50 value of 69.45 μM in A549 cells, effectively impeding Akt activity.Formule :C19H14ClN5O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :411.864-Isopropoxybenzoic acid
CAS :4-Isopropoxybenzoic acid (AI3 12104) is a Centromere-Associated Protein E inhibitor.Formule :C10H12O3Degré de pureté :98.58%Couleur et forme :White To Off-White PowderMasse moléculaire :180.2
