Hétérocycles azotés (N)

Please enquire for more information about 3-(4-Oxopyridin-1(4H)-yl)propanenitrile including the price, delivery time and more detailed product information at the technical inquiry form on this page

4-Bromoindole is a model compound that serves as a building block for the synthesis of pharmaceutically important compounds. 4-Bromoindole has been shown to have high catalytic rates for the oxidative coupling of zirconium oxide. This compound can also be used in asymmetric synthesis because it is able to form both R and S enantiomers in moderate yield. The reaction mechanism is thought to involve a nucleophilic attack by bromide on the carbonyl group, followed by elimination of hydrogen bromide from this intermediate. 4-Bromoindole can be synthesized in three ways: (1) via an oxidative coupling reaction with ZrOCl2 and H2O2; (2) via an oxidative coupling reaction with ZrOCl2 and HBr; or (3) by reacting 4-bromoaniline with CuSO4 and Mn(NO3)2.

Please enquire for more information about 2-Diethylaminopyrimidine-5-boronic acid, pinacol ester including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 4-Amino-6-phenyl-1,6-dihydro-1,3,5-triazine-2-thiol including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about tert-Butyl 3-amino-4,4-diethoxypiperidine-1-carboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page

Applications 2-[[6-Amino-5-(4-bromophenyl)-4-pyrimidinyl]oxy]-ethanol is a degradation product of Macitentan (M105005). References Thummar, Mohit, et al.: Chromatographia, 81(3), 525-531 (2018)

Please enquire for more information about Ethyl 2-methyl-imidazo[1,2-a]pyrimidine3-carboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 1-(4-Amino-1-Piperidinyl)-2,2,2-Trifluoroethanone including the price, delivery time and more detailed product information at the technical inquiry form on this page

3,4,5-Trichloropyridine-2-carboxylic acid is an organic solvent that is soluble in water. It has been shown to be a bidentate ligand with the ability to bind metal ions such as copper and nickel. 3,4,5-Trichloropyridine-2-carboxylic acid has also been used as a molecular probe for studying the interactions of hydrochloric acid with molecules. The carboxylic acid group found on 3,4,5-Trichloropyridine-2-carboxylic acid can be oxidized by electrolysis to form picolinic acid. This process occurs in crop plants and tissue culture cells. The residue of this process is plant tissue that contains picolinic acid and its derivatives such as pyridine ring. This product also has an acidic nature due to the presence of carboxylic acids.

Please enquire for more information about 3,4-Dihydro-1(2H)-pyridinecarboxylic acid phenylmethyl ester including the price, delivery time and more detailed product information at the technical inquiry form on this page

Applications 5-Hydroxycytosine, is been identified as an anomalous base of phage H-17 DNA. It is also a monosubstituted cytosine, as nucleotide-base antimetabolite-type potential anticarcinogen. References Khromov, I. S. Doklady Akademii Nauk SSSR, 240, 1486 (1978); Ladik, J., et al.: Magyar Kemiai Folyoirat, 76, 589 (1970);

Please enquire for more information about (3R,4R)-Ethyl4-phenylpiperidine-3-carboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 1-(5-Nitro-2-pyridinyl)piperidine-3-methanol including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 3-Amino-5-(2-thienyl)thieno[2,3-d]pyrimidin-4(3H)-one including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 3-Bromo-6,7-dihydro-5H-cyclopenta[b]pyridine including the price, delivery time and more detailed product information at the technical inquiry form on this page

Pyridine-2,5-dicarboxamide is an electron microscopic agent that has been shown to induce autophagy. This drug can be used as a ligand for the identification of unsaturated fatty acids and linkers in the functionalities of these molecules. Pyridine-2,5-dicarboxamide also has been shown to have anti-inflammatory activities through its inhibition of phospholipase A2 (PLA2) and subsequent reduction in arachidonic acid release from membrane phospholipids. Pyridine-2,5-dicarboxamide binds to PLA2 as a competitive inhibitor and prevents cleavage of the phospholipid substrate. The binding also disrupts the conformation of PLA2, preventing it from carrying out further enzymatic activity.

6-Fluoro-3-(4-piperidinyl)-1,2-benzisoxazole is a drug candidate that belongs to a new class of atypical antipsychotics. It has been synthesized using an efficient method and was found to bind to the m1 receptor with high affinity. 6-Fluoro-3-(4-piperidinyl)-1,2-benzisoxazole has shown efficacy in vitro studies against 5HT1a receptors and in vivo studies against fibroblast cells. This drug is also effective against serotonin levels, which may be due to its ability to inhibit the reuptake of serotonin by blocking the serotonin transporter.

Please enquire for more information about 1-[4-(4-Fluorophenyl)-1,3-thiazol-2-yl]piperazine trihydrate including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 2-Phenylpiperidine-2-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about N-(2,4-Difluorophenyl)-N'-(4,6-dimethylpyrimidin-2-yl)guanidine including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about Ethyl 6-chloroimidazo[1,2-b]pyridazine-2-carboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page

3-Vinyl-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one (RIS) is a neuroleptic drug that belongs to the class of phenothiazine. RIS is used for the treatment of schizophrenia and other psychotic disorders. The chemical synthesis process of RIS involves a four step sequence: 1) Nucleophilic substitution of 3,5 dimethoxyphenylacetonitrile with methyl iodide in an inert solvent such as tetrahydrofuran; 2) Protection of the reactive amino group by forming an acetal with ethylene glycol; 3) Alkylation of the acetal with propargyl bromide in the presence of a base such as sodium hydride; 4) Hydrolysis and decarboxylation of the resulting compound.

Please enquire for more information about 2-(2-Methoxy-ethoxy)-5-(4,4,5,5-tetraMethyl-[1,3,2]dioxaborolan-2-yl)-pyridine including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 3-Hydroxy-4-nitropyridine including the price, delivery time and more detailed product information at the technical inquiry form on this page

(S)-(+)-2-Methylpiperidine is a gaseous amine that is synthesized from the reaction of methylamine and formaldehyde. It has been shown to have a variety of different orientations, including alpha, beta, and gamma. The molecule's stereoisomers have also been shown to differ in their profiles, with some being more stable than others. Preparative high performance liquid chromatography (HPLC) can be used to purify the compound enantiopure if it is desired. The kinetic and metric data for this molecule are available as well. In addition, (S)-(+)-2-Methylpiperidine has been studied for its effects on chemical diversity as well as environmental effects.

Please enquire for more information about 2H-Pyrido[2,3-d][1,3]oxazin-2-one,7-[2-(cyclopropylmethoxy)-6-hydroxyphenyl]-1,4-dihydro-5-(3S)-3-piperidinyl- including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 1-(Chloroacetyl)piperidin-4-amine hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page

2,4,6-Tri-tert-butylpyrimidine is a chemical compound that has been found to have diverse biological properties. It has been shown that 2,4,6-Tri-tert-butylpyrimidine can be used as an n-oxide to synthesize oligosaccharides and synthetic molecules. It has also been shown to be a useful reagent in the synthesis of disaccharides and related compounds. The phosphate group on this molecule is key in its biological properties. This molecule is also useful for solid phase synthesis. Diphenyl sulfoxide is often used as a protecting group during the synthesis of this molecule. 2,4,6-Tri-tert-butylpyrimidine has been studied for its effects on pancreatic cancer cells and was found to inhibit cell proliferation.

Please enquire for more information about (S)-Benzyl (2,6-dioxopiperidin-3-yl)carbamate including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 4-Benzylpiperidine-4-carboxylic acid hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page

Applications α-Butyl-α-(2,4-dichlorophenyl)-4H-1,2,4-triazole-4-ethanol is a useful synthetic intermediate.

Please enquire for more information about (R)-N-Benzyloxycarbonyl-2-piperidinecarboxaldehyde including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 4-(5,7-Dioxo-5,7-dihydro-6H-pyrrolo[3,4-b]pyridin-6-yl)butanoic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 4-[(4-Methyl-2-piperidin-1-ylquinolin-6-yl)amino]-4-oxobutanoic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

N,N-Bis(pyridin-3-ylmethyl)amine is a fluorescent probe that is used for the determination of ciprofloxacin, which is an antibiotic. It can be detected by optical imaging, and has a linear range of 1 to 10 μM. This compound is also useful for assays, as it exhibits high detection at low concentrations and can be used in strategies to detect other compounds. N,N-Bis(pyridin-3-ylmethyl)amine displays red fluorescence with an excitation wavelength of 400 nm and emission wavelength of 510 nm. It has been shown to have strong optical properties that are suitable for use in pharmaceutical preparations as well as conjugates with silicon nanoparticles.

Applications 3-(N-1-Trityl-imidazol-4-yl)propionic Acid is an intermediate used to prepare imidazole-containing tetrahydrobenzodiazepine inhibitors of farnesyltransferase. It is also used in the synthesis of nonracemic arylpiperazinone analogs of the carboxyl-terminal CAAL sequence of protein geranylgeranyltransferase-I (PGGTase-I) as selective inhibitors of PGGTase-I and of protein farnesyltransferase. References Ding, C., et al.: J. Med. Chem., 42, 5241 (1999); Peng, H., et al.: Org. BIomol. Chem., 4, 1768 (2006)

4,6-Dichloropyrimidine is an intermediate in the production of malonic acid. It is also used as a process optimization agent in the synthesis of hydrochloric acid and water vapor. 4,6-Dichloropyrimidine reacts with hydrogen chloride to form a chlorinating agent that can be used for the chlorination of amines and alcohols. The reaction product is hydrochloric acid and dichloropyrimidine. This intermediate can also be used to synthesize amides through a Suzuki coupling reaction with hydroxyl groups, amines, and n-dimethyl formamide.

Please enquire for more information about 2-Aminopyrimidine-5-carbaldehyde hydrate including the price, delivery time and more detailed product information at the technical inquiry form on this page

4-Methoxy-2-phenylpyridine is a pyridine with the chemical formula CH3O-C6H4-CH3. It has been used to study the efficiencies of various cations. The reaction of 4-methoxy-2-phenylpyridine with anions such as Cl-, Br-, I-, and SO42-, produces aryl chlorides, bromides, iodides, and sulfonates in high yield. This compound can be used to synthesize organic light emitting diodes (OLED) for use in displays and lighting.

Please enquire for more information about 4-(1,3-Dioxo-1,3-dihydro-2H-pyrrolo[3,4-c]pyridin-2-yl)benzoic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 3-(3-Aminopyridin-2-yl)-5-(trifluoromethyl)-1,3-oxazolidin-2-one including the price, delivery time and more detailed product information at the technical inquiry form on this page

Applications Piperonyl Isobutyrate (cas# 5461-08-5) is a useful research chemical.

Please enquire for more information about rac-(7R,9aR)-Octahydro-1H-pyrido[1,2-a]pyrazine-7-carboxylic acid dihydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page