Hétérocycles azotés (N)

Please enquire for more information about 2-chloro-3-fluoropyridin-4-amine including the price, delivery time and more detailed product information at the technical inquiry form on this page

Applications 5-Ethyl-2-pyridineethanol (cas# 5223-06-3) is a compound useful in organic synthesis.

6-Fluoroindole-3-carboxaldehyde (6FLA) is a synthetic compound that inhibits biosynthesis of the phytoalexins salicylic acid and lignin in plants. It also inhibits the β-glucuronidase enzyme, which hydrolyzes the glucuronide conjugates of phenolic compounds and xenobiotics. 6FLA has been shown to cause mild liver damage in rats, but its effects on humans are unknown. 6FLA may be used as a detectable substance for assays.

2-Bromo-4-(trifluoromethyl)pyridine is a molecule that is used as an acceptor in organic semiconductor devices. It has low efficiency and a red shift in the optical properties of the molecule. The hydrophobic phenyl groups are responsible for the transfer of electrons to the device. 2-Bromo-4-(trifluoromethyl)pyridine is used in a Suzuki coupling reaction to synthesize polymers with desired optical properties. This functional theory has been shown to be effective for polymers with high efficiencies and low molecular weight.

5-Methoxypyrimidine is a chemical compound that inhibits the activity of methanol and ethyl formate by forming 5-methoxyuridine. It can be used as an intermediate in the production of pharmaceutical drugs. 5-Methoxypyrimidine has been shown to inhibit the kinase activity of many different enzymes, including tyrosine protein kinases, serine protein kinases, and threonine protein kinases. This chemical also has alkylating properties, which may be useful for industrial purposes such as pesticide manufacture.

Please enquire for more information about 4,5,6,7-Tetrahydropyrazolo[1,5-a]pyridine-2-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

Cyclo-Val-Pro-diketopiperazine is a drug that inhibits the growth of colon cancer cells by inducing apoptosis. It has been shown to have an inhibitory effect on the proliferation of p. aeruginosa and other bacteria, which may be due to its ability to interfere with DNA replication. Cyclo-Val-Pro-diketopiperazine also induces tumor cell apoptosis in vitro. The mechanism for this is not yet known, but it may involve interference with mitochondrial membrane potential or inhibition of acetate extraction from colonic cells. In addition, this drug has been shown to induce apoptosis in colorectal adenocarcinoma cells by causing an increase in reactive oxygen species and a decrease in mitochondrial membrane potential. Cyclo-Val-Pro-diketopiperazine can cause an increase in the levels of acetate extractable from caco2 cells as well as a decrease in mitochondrial membrane potential, which are both

Please enquire for more information about 2-[(5-Bromopyridin-2-yl)methylamino]ethanol including the price, delivery time and more detailed product information at the technical inquiry form on this page

4-Chloro-5-Fluoro-2(1H)-Pyrimidinone is a highly stable chemical compound that has cytotoxic properties. It is commonly used as an inhibitor in various research studies and is also utilized as an intermediate in the synthesis of other compounds. This versatile compound can react with aldehydes, cytidine, cefaclor, hydrogen atoms, adenine, and many other substances. Additionally, 4-Chloro-5-Fluoro-2(1H)-Pyrimidinone has antiviral properties and is known to inhibit the growth of certain viruses. Its fluorine content contributes to its effectiveness against viral infections. Furthermore, this compound can be used in the production of disaccharides and 5-aminolevulinic acid.

Please enquire for more information about 4-(3-Ethyl-1,2,4-oxadiazol-5-yl)piperidine including the price, delivery time and more detailed product information at the technical inquiry form on this page

Applications Isotope labelled B-[1-(Tetrahydro-2H-pyran-4-yl)-1H-pyrazol-4-yl]boronic Acid is used in the preparation of ALK receptor mediators.

Please enquire for more information about 2-Fluoro-5-Methylpyridine-3-boronic acid pinacol ester including the price, delivery time and more detailed product information at the technical inquiry form on this page

4,6-Dichloropyrido[3,2-d]pyrimidine is a hydroxamic acid with oncogenic properties. It has been shown to induce tumor growth in animal models and is believed to work by inhibiting the activation of signaling pathways that control cell proliferation. 4,6-Dichloropyrido[3,2-d]pyrimidine inhibits the activation of oncogenic signaling pathways by binding to phosphorylated serine/threonine residues in their kinase domains. This drug also has antiproliferative activity on prostate cancer cells in culture.

Racemic cis-1-benzyl-2-methyl-4-(N-propananilido)piperidine (SBP) is a synthetic opioid analgesic that has been shown to bind to the μ-opioid receptor. It is the racemic form of the more potent S(+)-isomer. SBP is metabolized in vivo by cytochrome P450 2C19 and cytochrome P450 3A5, and its metabolites can be detected in human liver. The metabolism of SBP also produces propanamide as an intermediate. Recreational use of SBP has been reported with adverse effects including nausea, vomiting, headache, and dizziness.

Please enquire for more information about N-Methyl-N-(tetrahydrofuran-2-yl)piperidin-4-amine including the price, delivery time and more detailed product information at the technical inquiry form on this page

Applications N-(5-formylpyrimidin-2-yl)glycine (cas# 915923-65-8) is a useful research chemical.

Please enquire for more information about 2-(5-Bromopyridin-2-yl)acetic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 1-(3-Chloropropyl)piperazine dihydrochlorideHemi-hydrate including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 4-Amino-N-(pyridin-2-ylmethyl)benzenesulfonamide including the price, delivery time and more detailed product information at the technical inquiry form on this page

4-Thiothymidine is a nucleoside analog that is used in the treatment of cancer. It binds to the phosphoribosyl transferase enzyme, which is necessary for the synthesis of thymidylate from uridine. This prevents DNA replication and leads to cell death. 4-Thiothymidine can also be used in combination with other drugs such as l1210 and uridine. The drug binds to an allosteric site on uridine phosphorylase, which is an enzyme that is vital for the conversion of uridine into thymine. The binding inhibits nucleophilic attack by phosphate on the carbonyl group at position 3 of the substrate, preventing phosphorylase activity. 4-Thiothymidine has been shown to increase muscle mass in animal models.

Intermediate in the synthesis of baricitinib

2-Bromo-3-methoxy-6-methylpyridine is a molecule that has been synthesized as an experimental probe to study the proton transfer process. It has been shown to be reactive, with a magnetic moment and predictable constants. The electron density and geometries can be calculated for this molecule, which is useful for predicting the parameters of proton transfer. 2-Bromo-3-methoxy-6-methylpyridine has been found to have intramolecular hydrogen bonding and resonance, which may be important in understanding the properties of this molecule.

Please enquire for more information about 3,5-Dibromo-4-fluoro-2-pyridinamine including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 2-{2-[4-(2-Furoyl)piperazin-1-yl]-2-oxoethoxy}benzonitrile including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about N-Benzyl-4-amino-piperidine-4-carboxamide including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about RC-3095 trifluoroacetate including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 7-Bromo-1H-pyrazolo[4,3-b]pyridine including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about tert-Butyl3-oxospiro[indan-1,4'-piperidine]-1'-carboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page

5-Methoxyindole is a chemical compound that is soluble in water. It has been shown to inhibit tumor growth and induce apoptosis, as well as inhibit the expression of glycogen synthase kinase-3. The structure of 5-methoxyindole was determined by NMR spectroscopy and FT-IR spectroscopy. The compound has been observed to exhibit fluorescence properties at a wavelength of 490 nm when it is excited with UV light. A copper complex of 5-methoxyindole was studied using molecular modeling and FT-IR spectroscopy, which revealed that it can undergo nucleophilic attack by hydrogen bond formation or an acid/base reaction to form a new hydrogen bond. This study also found that 5-methoxyindole is able to form hydrogen bonds with its neighboring molecules, which may contribute to its high solubility in water.

Please enquire for more information about N-(4-Methylbenzyl)-1'H-spiro[piperidine-4,2'-quinoxalin]-3'-amine including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 4-(2-Chloro-5-fluoropyrimidin-4-yl)morpholine including the price, delivery time and more detailed product information at the technical inquiry form on this page

2-(4-Chlorobenzyl)pyridine is a synthetic pyridine compound that has been shown to have anti-cancer properties. It is also a potent inducer of the enzyme methane monooxygenase and has been shown to interact with other compounds, such as maleates and sulfoxides, which are also used in this type of experiment. The catalytic mechanism for 2-(4-chlorobenzyl)pyridine is not yet known, but it may involve an acidic chlorine atom or a hydrochloric acid catalyst. 2-(4-Chlorobenzyl)pyridine has been found to be effective at inhibiting the growth of cancer cells in vitro without toxic effects on healthy cells. It has also been shown to inhibit the proliferation of human leukemia cells in vivo.

(R)-(-)-a-[[(4-Ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]benzeneacetic Acid is an inhibitor of the enzyme histamine N-methyltransferase (HNMT), which is responsible for the synthesis of histamine. The inhibition of HNMT leads to a decrease in histamine levels and therefore has been used as a treatment for chronic prostatitis, lacrimal gland, and energy efficiency. Histamine N-methyltransferase also participates in the regulation of apoptosis by methylating proapoptotic proteins like Bax, so inhibition can lead to an increase in apoptosis. This chemical is also able to bind with chloride ions and form diphenyl ethers through a reaction solution, which are known to have anticancer properties.

Please enquire for more information about Benzyl 4-amino4-methylpiperdine-1-carboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about tert-Butyl methyl(piperidin-4-ylmethyl)carbamate including the price, delivery time and more detailed product information at the technical inquiry form on this page

Applications Ethyl-2-ethoxy-1-[[(2'-cyanobiphenyl-4-yl) methyl] benzimidazole]-7-carboxylate

2-Methylindole is a reactive molecule that can undergo electrophilic substitution at the 2-position. It reacts with a variety of nitrogen nucleophiles, acylating them at the 2-position. These reactions are catalyzed by enzymes such as carbonyl reductase and methyl ketone reductase. The reaction mechanism is not yet fully understood, but it has been proposed that it proceeds through an acylation reaction between two molecules of 2-methylindole to form a linear product. The regiospecificity of this reaction has been demonstrated in vivo using a model system.

Please enquire for more information about 2-Chloro-N-[2-(cyclopropylamino)-4-methyl-3-pyridinyl]-3-pyridinecarboxamide including the price, delivery time and more detailed product information at the technical inquiry form on this page

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