Hétérocycles azotés (N)

Please enquire for more information about 5-(Chloromethyl)-2-Fluoropyridine including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 2-(Dimethylamino)-4-methylpyrimidine-5-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

3-Phenylpiperidine hydrochloride (3PPH) is a drug that has been postulated to be an inhibitor of phosphatases. It has been shown to inhibit the activity of the enzyme matrix metalloproteinase, which is involved in tumor invasion and metastasis. 3PPH also binds to the dopamine receptor, but with a lower affinity than other ligands. 3PPH has been shown to have an inhibitory effect on dopamine induced phosphatase activation in HL-60 cells.

Please enquire for more information about 2-[(3,4-Dimethylphenyl)amino]-5,6-dimethylpyrimidin-4(3H)-one including the price, delivery time and more detailed product information at the technical inquiry form on this page

Applications 4-Amino-2-chloro-3-methylbenzonitrile is a reagent used in synthesis of imidazolin-2-ones, which is designed and synthesized as highly potent, orally active and muscle selective androgen receptor modulators (SARMs). References Li, J. J., et al.: J. Med. Chem., 50, 3015-3025 (2007)

4-Iodopyridin-3-ol is a reactive ligand that binds to magnesium ions. It is used as an inhibitor of transporters, such as the serotonin transporter and the chloride transporter. 4-Iodopyridin-3-ol has been shown to have antidepressant effects in mice, which may be due to its ability to inhibit monoamine oxidase (MAO). It also has an effect on brain uptake and yields, which are dependent on the substitution of the pyridine ring.

3-Amino-4-nitropyridine is a nucleophilic amine that can be used to synthesize 3-amino-4-nitropyridines. 3-Amino-4-nitropyridine has been shown to react with chlorides and nitro compounds to form 3,4-dichloropyridines and 3,5-dinitropyridines, respectively. The reaction of 3-amino-4-nitropyridine with methoxyamine forms 4-(3′,5′)-aminopyrimidinium methoxide. This product has been shown to be a stoichiometric reagent in the formation of substituted piperidines from methoxyamine and nitroethane.

Applications 6,7-Dihydro-Imidazo[1,5-a]pyrazin-8(5H)-one is a useful research chemical.

Please enquire for more information about 4-(2-Chloro-4-nitrophenyl)piperazine-1-carboxamide including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 6-Aminopyrimidine-4-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 2-Ethylpyrimidine-5-carbaldehyde including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 2-Chloro-3,6-dimethylpyridine including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 5-piperidinylmethyl Esculetin including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 2-Methyl-4,5,6,7-Tetrahydro-3H-Imidazo[4,5-C]Pyridine Dihydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 1-(Phenylsulfonyl)piperidin-4-amine hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page

5-Bromo-6-chloropyrimidin-4-amine is a cellular analog that was synthesized in order to study the effects of carboxamide on tumor growth. It has been shown to have an inhibitory effect on human cancer cells, with a dose-dependent response. 5-Bromo-6-chloropyrimidin-4-amine binds to DNA and inhibits carboxypeptidase A, which is involved in protein biosynthesis. This analog also interacts with the enzyme carboxypeptidase B, which catalyzes the formation of amino acids from amino acid precursors. 5-Bromo-6-chloropyrimidin-4-amine has been shown to inhibit tumor growth through inhibition of these enzymes.

2,6-Dimethyl pyrazine is a chemical compound that is used as a matrix effect reagent to improve the absorption of other compounds in gas chromatography. 2,6-Dimethyl pyrazine can be used as an alternative to fatty acids in solid phase microextraction. It has been shown to have a kinetic energy of 147 kJ/mol and uv absorption at 205 nm. The compound has been synthesized using reactions including hydrogenation, condensation, and nitration methods. This product is not toxic to humans and has a molecular weight of 128.2 g/mol. The compound has been shown to have coordination geometry with two nitrogen atoms and one carbon atom, which are bound by three hydrogen atoms on the right side of the molecule. FTIR spectroscopy studies show that this product absorbs at 1630 cm−1. The group designation for this product is p2.

Please enquire for more information about 4-Isothiocyanato-N-(3-methoxypyrazin-2-yl)benzenesulfonamide including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 1-(4-Chlorobenzoyl)piperidine-3-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 4-(1H-Pyrazol-1-ylmethyl)piperidin-4-ol including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 7-Amino-5-methylpyrido[3,4-e][1,2,4]triazolo[1,5-a]pyrimidin-6(7H)-one including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 2-Pyridin-3-ylethanimidamide dihydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 2-Chloro-7-methyl-7H-pyrrolo[2,3-d]pyrimidine including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about {3-[(E)-2-Pyridin-4-ylvinyl]phenyl}amine including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 3-Amino-6-trifluoromethylpyrazine-2-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

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Please enquire for more information about 1-Boc-4-cyclopropylaminopiperidine including the price, delivery time and more detailed product information at the technical inquiry form on this page

4-Chloro-6-ethoxy-2-methylsulfanyl-pyrimidine is a pyrimidine compound that has been synthesized and characterized by infrared spectroscopy, metathesis reaction, and chalcone. The structure of the molecule was confirmed by spectral data. It reacts with eugenol and also reacts with infrared light. 4-Chloro-6-ethoxy-2-methylsulfanyl-pyrimidine was synthesized in Switzerland.

Please enquire for more information about 1,1'-Diphenyl-4,4'-bipyridinium Dichloride including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 2-(Piperidin-1-ylmethyl)-1,4-oxazepane including the price, delivery time and more detailed product information at the technical inquiry form on this page

2-Aminoimidazole sulfate is a chemical compound that is used as a transfection reagent. It has been shown to have high transfection efficiency with low cytotoxicity. The diameter of the molecule is in the range of 2 - 3 nm, which allows it to be taken up by cells and thus be active in them. This chemical can be dehydrogenated to form imidazole-2-sulfonic acid, which may interact with other molecules. There have been many advances in this area, including modifications and gaseous forms of the molecule. Research into the interactions of this compound with other chemicals and their effects on cellular uptake are ongoing.

Please enquire for more information about 4-[(Pyridin-2-yl)methyl]piperidine dihydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page

Applications Used in ointments for treatment of psoriasis. References Wetterau, J., et al.: Biochim. Biophys Acta, 1345, 136 (1997), Sorbera, L., et al.: Drugs Future, 25, 1138 (2000), Robl, J., et al.: J. Med. Chem., 44, 851 (2001), Theuns, J., et al.: Neurolog. Aging, 25, S85 (2004),

2-Isopropyl-5-methylpyrazine is an organic acid that can be produced synthetically or isolated from various plants. It is a secondary metabolite of fungi and bacteria, which can be found in composts, decaying plants, and soil. 2-Isopropyl-5-methylpyrazine has a variety of uses, including as a food flavoring agent and as an intermediate in the production of other chemicals. 2-Isopropyl-5-methylpyrazine has shown resistance to chemical degradation by air oxidation and microbial transformation. This compound is also resistant to tryptic digestion and it decomposes at elevated temperatures.

Stability Hygroscopic Applications 2,6-Dimethoxypyridine-3,5-diamine hydrochloride (cas# 56216-28-5) is useful component in hair dyes. Has cosmetic applications. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Krohn, R., et al.: PCT Int. Appl. (2020), WO 2020089365 A1

3-Hydroxypiperidine is a chemical compound that contains an asymmetric carbonyl group. It has been used in the synthesis of enantiopure pharmaceuticals, and is also a competitive inhibitor for some enzymes. 3-Hydroxypiperidine can be synthesized by hydrogenation reduction or hydroxylation of piperidine. This compound has been shown to have pharmacokinetic properties in rats and mice, as well as inhibitory effects on brain functions such as memory retention and learning. 3-Hydroxypiperidine has also been shown to induce apoptosis in breast cancer cells, which may be due to its ability to inhibit protein synthesis in these cells.

Applications N,1-Dimethyl-4-nitro-5-imidazolecarboxamide (cas# 858513-51-6) is a compound useful in organic synthesis.

Please enquire for more information about 1-(6-Amino-1,3-benzodioxol-5-yl)piperidin-2-one including the price, delivery time and more detailed product information at the technical inquiry form on this page

Piperazine trityl resin is an organic compound that can be used as a molecular probe to detect the presence of nucleophilic groups. It is activated by treatment with acid and reacts with nucleophilic groups, such as those found in human serum. Piperazine trityl resin can also be used to detect proteolytic activity in human serum samples. The interaction between this compound and proteolytic enzymes leads to the formation of a colored product that can be detected using diagnostic methods, such as chromatography or spectrophotometry. The detection of proteolytic activity can be used for the diagnosis and detection of various diseases, including fulminant hepatitis.

2-[(4-Chlorophenyl)(4-piperidinyloxy)methyl]-pyridine is a chemical compound with molecular formula C12H11ClN2O. It has a crystalline form, and diffraction data can be obtained from the substance. This chemical is soluble in organic solvents such as salicylic acid, acetonitrile, butanoic acid, and methyl ethyl ketone. The 2-[(4-chlorophenyl)(4-piperidinyloxy)methyl]-pyridine has been used in the synthesis of various other compounds, including optical isomers and ketones.

Please enquire for more information about 4-Methyl-5-pyridin-3-yl-4H-1,2,4-triazole-3-thiol including the price, delivery time and more detailed product information at the technical inquiry form on this page

Applications 6-Chloro-2-methoxypyridine-3-boronic acid

5,6-Difluoroindole is a chemical compound that has been studied in biological and chemical research. It is an analog of the neurotransmitter serotonin, which binds to the 5-HT2C receptor and activates phospholipase C (PLC) to produce inositol triphosphate (IP3). This compound may be useful for the treatment of neurodegenerative diseases such as Alzheimer's disease. 5,6-Difluoroindole has been shown to block the activity of acetylcholinesterase (AChE), which is an enzyme that breaks down acetylcholine. This leads to an increase in acetylcholine levels and a decrease in AChE activity. The reaction mechanism for this process is not known.

Please enquire for more information about 1-[(2,5-Dichlorophenyl)sulfonyl]piperidine-4-carbohydrazide including the price, delivery time and more detailed product information at the technical inquiry form on this page

2-(Piperidin-4-yloxy)pyridine is a drug that has been evaluated for its ability to stabilize the active ingredient of a formulation. It has been shown to be a predictive excipient, which can help predict the stability of an active ingredient in an oral dosage form. The most commonly used method for evaluating the effects of excipients on the stability of pharmaceuticals is by screening. 2-(Piperidin-4-yloxy)pyridine has been screened and found to be a good stabilizer. This molecule is hypothesized to stabilize the active ingredient by binding to ionic sites on the protein's surface and preventing aggregation. Monoclonal antibodies are also often used as excipients because they bind tightly and specifically with their target antigens, leading to better stabilization.

S-[2-(Iodo-4-azidosalicylamido)ethylthio]-2-thiopyridine is a hydroxyl group containing inhibitor of the histone deacetylase (HDAC) enzyme. It has been shown to reduce blood pressure and inhibit bacterial enzyme activity in a mouse model. S-[2-(Iodo-4-azidosalicylamido)ethylthio]-2-thiopyridine has also been shown to be effective at reducing the growth rate of subcutaneous tumors in mice that are induced with radiation, suggesting it may have anti-cancer properties. It can also be used as a nutritional supplement to increase the production of fatty acids and growth factors.

5-Bromo-1,3-dihydro-2H-pyrrolo[2,3-b]pyridin-2-one is a cancer drug that is a potent inhibitor of angiogenesis. This compound has been shown to inhibit tumor growth in vitro and in vivo. 5-Bromo-1,3-dihydro-2H-pyrrolo[2,3-b]pyridin-2-one also shows antiangiogenic activity in mouse models of cancer. The antitumor effects of this drug are mediated by inhibition of the protein tyrosine kinases VEGF receptor 1 (VEGFR1) and VEGFR2. Sunitinib is an oral anticancer agent used for the treatment of metastatic renal cell carcinoma and other solid tumors. It has been found to be active against a variety of human cancers including melanomas, lung cancers, breast