Hétérocycles azotés (N)

Please enquire for more information about Ethyl (R)-1-(tert-Butoxycarbonyl)-3-piperidinecarboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page

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6-Chloropyridazine-3-carboxamide is a chemical compound with the formula (CHCl)N. It is a white solid that can be prepared by reacting methyl esters and butylamine with boron trifluoride etherate in the presence of boron trifluoride. The reaction sequence starts with the addition of methyl esters to a solution of boron trifluoride etherate, followed by the addition of butylamine. The product crystallizes from methanolic and etherial solutions as colorless needles. 6-Chloropyridazine-3-carboxamide is used as an intermediate in organic syntheses such as peptides, pharmaceuticals, and pesticides.

6-Chloropyrazin-2-ol is a benzyl derivative of hydroxypyrazine. It is an analogue of the nucleophilic reagent, 2,6-dichloro-1,3,5-triazine. The compound has been reexamined and synthesized as a potential precursor to fluorinated benzene derivatives. 6-Chloropyrazin-2-ol can be used in the synthesis of demethylated benzene derivatives or as a precursor to the synthesis of other compounds with tautomerism involving fluoride.

Please enquire for more information about 3-(1,3-Dioxo-1,3-dihydro-2H-pyrrolo[3,4-c]pyridin-2-yl)benzoic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about tert-Butyl 3-bromo-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazine-7(8H)-carboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 1-Boc-4-cyclobutylaminopiperidine including the price, delivery time and more detailed product information at the technical inquiry form on this page

N-[2-[6-[[4-(Cyclobutylamino)-5-(trifluoromethyl)-2-pyrimidinyl]amino]-1,2,3,4-tetrahydronaphthalen-1,4-imin-9-yl]-2-oxoethyl]acetam ide (NXD101) is a transcriptional regulator that inhibits the activity of histone methyltransferase (HMT). It has been shown to be effective in prostate cancer cells and solid tumours. The molecule also inhibits the expression of caspase 3 and p21 in mouse tumor models. NXD101 interacts with the ATP binding site of HMT and blocks its activity by forming a ternary complex with the enzyme and DNA. This inhibition prevents methylation of lysine 27 on histone H3 (H3K27me), which is essential for maintaining cell viability. The drug also has high selectivity for

Bioavailable form of vitamin B6; coenzyme; food supplement

Please enquire for more information about ETHYL 2,6-DICHLORO-5-NITROPYRIMIDINE-4-CARBOXYLATE including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 6-(Chloromethyl)-N-(2-methoxy-5-methylphenyl)-1,3,5-triazine-2,4-diamine including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 6-Bromooxazolo[5,4-b]pyridine including the price, delivery time and more detailed product information at the technical inquiry form on this page

Applications 4-Aminopiperidine-3,3,4,5,5-d5 (CAS# 1219803-60-7) is a useful isotopically labeled research compound.

Applications 4-[4-[(5R)-5-(Aminomethyl)-2-oxo-3-oxazolidinyl]phenyl]-3-morpholinone Hydrochloride is an intermediate in the synthesis of ent-Rivaroxaban (R538005), the R-isomer of Rivaroxaban (R538000), which is a novel antithrombotic agent. References Eriksson, B., et al.: J. Thromb. Haemost., 3, 103 (2005), Kubitza, D., et al.: Clin. Pharmacol. Ther., 78, 412 (2005),

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3-Ethylpyridine is a type of compound that has been found in bacteria. It has been shown to be a mitochondrial membrane potential inhibitor and matrix molecules inducer. 3-Ethylpyridine also inhibits the mitochondrial pathway of 2-ethylpyridine, which is a major metabolite of nicotine in mammals. This inhibition leads to lung cancer. 3-Ethylpyridine can be used as an alternative to chemotherapeutic agents for lung cancer treatment.

Please enquire for more information about 8'-Chloro-5'H-spiro[piperidine-4,4'-pyrrolo[1,2-a]quinoxaline] including the price, delivery time and more detailed product information at the technical inquiry form on this page

2-Phenylimidazole is used to prepare complex compounds with ruthenium(III) and also as an intermediate for agrochemical, pharmaceutical and specialty products. It also finds its application as a curing agent for epoxy resins and polyurethane. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Please enquire for more information about 3',4'-Dihydro-2'H-spiro[cyclopentane-1,1'-pyrrolo[1,2-a]pyrazine] including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about (3S)-4-Boc-1-carboxymethyl-3-methyl-piperazin-2-one including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 1-(Tetrahydro-2H-pyran-4-yl)piperidine-3-carboxylic acid hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page

4,6-Dichloro-1H-pyrazolo[4,3-c]pyridine is a reagent that has been used as a building block for the synthesis of other compounds. It is also used in the preparation of a variety of organic compounds. 4,6-Dichloro-1H-pyrazolo[4,3-c]pyridine is soluble in organic solvents such as chloroform and ethanol, and can be stored at room temperature. This compound reacts with acids to produce an acid chloride that are useful for the formation of amides and esters. This product has been shown to have a high quality and is suitable for use in research or development.

Please enquire for more information about Ethyl 5-cyclopropyl-7-(difluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page

Applications 2,5-Di-4-pyridinylpyrazine is a compound used in the preparation of isonicotonic acid derivatives used in the chemotherapy of tuberculosis. References Cymerman-Craig, J., et al.: J Chem Soc., 4315-20 (1955);

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4-Chloropyridine-2-carbonylchloride is a potent antitumor agent that belongs to the class of quinoline derivatives. It has been shown to inhibit protein synthesis and cancer cell growth in vitro and in vivo. The antitumor activity of 4-Chloropyridine-2-carbonylchloride may be due to its ability to inhibit the activation of growth factors such as epidermal growth factor (EGF). 4-Chloropyridine-2-carbonylchloride also inhibits DNA synthesis by inhibiting the activity of DNA polymerase alpha. This compound binds to surface methodology on cells, which may explain its potent antitumor activity.

Please enquire for more information about (2,3-Difluoropyridin-4-yl)boronic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

2,6-Dibromopyridine (2,6-DBP) is a chemical compound that has been used in the synthesis of other organic compounds. It is an aromatic heterocycle with nitrogen atoms at the 2 and 6 positions. 2,6-DBP is a monosubstituted pyridine derivative that undergoes a palladium-catalyzed coupling reaction with an aryl halide to form pyrazoles. This process can be done unsymmetrically by protonating the 2 position of the dibromopyridine molecule. The presence of serine protease has been shown to promote this reaction by increasing the surface area of the substrate.

Please enquire for more information about 4,5-Dihydro-1H-imidazol-2-amine hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 7-(3,4-Dimethoxyphenyl)pyrazolo[1,5-a]pyrimidine-2-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 2-Hydrazinyl-4-(Trifluoromethyl)-5-Pyrimidinecarboxylic Acid Methyl Ester including the price, delivery time and more detailed product information at the technical inquiry form on this page

1,4-Dinitrosopiperazine is a chemical compound that has been used as an anthelmintic drug and for the treatment of cancer. It is a structural analog of piperazine, but with two nitro groups on each amine group. 1,4-Dinitrosopiperazine can be synthesized from 2,6-diamino-3-nitropyridine and formaldehyde in the presence of sodium nitrite and potassium hydroxide. The reaction mechanism is similar to that of piperazine but with a different product. 1,4-Dinitrosopiperazine can be found in urine samples and reacts with sulfhydryl groups at cysteine residues to form stable adducts. In vitro studies have shown that these adducts inhibit acetylcholinesterase activity and may be responsible for its anticancer properties. 1,4-Dinitrosopiperazine inhibits the growth of squamous carcin

Please enquire for more information about 4-Chloro-5-nitro-2-hydroxypyridine including the price, delivery time and more detailed product information at the technical inquiry form on this page

Applications N-methyl-4,5,6,7-tetrahydro-2H-pyrazolo[4,3-c]pyridine-3-carboxamide hydrochloride (cas# 1219957-27-3) is a useful research chemical.

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3-Methyl-4-piperidone is a magnetic compound that can be used as an acid catalyst in the synthesis of pharmaceuticals. It is obtained by the reaction of propionic anhydride with aldehyde. This compound is synthesized through the use of various techniques and has been shown to have analgesic properties. 3-Methyl-4-piperidone can be reused and its conformation can be determined through techniques such as proton NMR spectroscopy, which can help in prioritizing this compound for further study.

2-Acetyl-6-methoxypyridine is a reactive intermediate that is used in the synthesis of morpholine and piperidine. This compound has been shown to have anti-cancer properties, with cytotoxic effects on HCT116 cells. It has also been shown to be an organometallic compound that can interact with nucleophilic groups. 2-Acetyl-6-methoxypyridine may also be used as an antibacterial agent, although there are no studies that have investigated its cellular interactions.

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