Hétérocycles azotés (N)

Please enquire for more information about 2-Cyano-N-(4-methylpyridin-2-yl)acetamide including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about (6-(1H-Pyrazol-1-yl)pyridin-3-yl)methanol including the price, delivery time and more detailed product information at the technical inquiry form on this page

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Please enquire for more information about 2-[4-(2-Furoyl)piperazin-1-yl]-5-nitrobenzonitrile including the price, delivery time and more detailed product information at the technical inquiry form on this page

3-[(2S)-1,2,3,6-Tetrahydropyridin-2-Yl]Pyridine is a compound that is derived from the plant metabolism. It has been shown to have a nicotine-like effect on locomotor activity in rats. 3-[(2S)-1,2,3,6-Tetrahydropyridin-2-Yl]Pyridine has also been shown to inhibit antibody production in mice and to be effective against bowel disease. The compound has also been studied for its ability to treat metabolic disorders such as diabetes. 3-[(2S)-1,2,3,6-Tetrahydropyridin-2-Yl]Pyridine is not toxic when administered orally over a long period of time.

Please enquire for more information about 5-Bromo-2-chloropyridine-4-boronic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

N-(2-Aminoethyl)-5-chloroisoquinoline-8-sulfonamide is a natural compound that has been shown to inhibit the enzyme secretase, which plays an important role in the development of cancer. The drug may also act as a signal pathway inhibitor by inhibiting the activity of phosphatidylinositol 3 kinase and protein kinase C (PKC). N-(2-Aminoethyl)-5-chloroisoquinoline-8-sulfonamide also inhibits the production of glutamate, a neurotransmitter, by blocking calcium channels in neurons. This drug has been shown to increase bone mass and decrease bone resorption in rats with bone cancer. It is also effective against solid tumours such as breast, lung, and prostate cancers. N-(2-Aminoethyl)-5-chloroisoquinoline-8-sulfonamide is structurally related to other drugs used for platinum based chemotherapy.

Please enquire for more information about 2,4-Dichloro-7-tosyl-7H-pyrrolo[2,3-d]pyrimidine including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about Ethyl 5-(1,3-dimethyl-1H-pyrazol-4-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page

Applications 7-Bromo-5-(pyridin-2-yl)-1H-benzo[e][1,4]diazepine-2(3H)-thione is used in the preparation of triazolobenzodiazepines with antianxiety and antidepressant activity. References Hester, J.B., et. al.: J. Med. Chem., 23, 392 (1980)

Please enquire for more information about 2-Chloro-N-{4-[(pyrimidin-2-ylamino)sulfonyl]phenyl}propanamide including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 1-Benzyl-5-methyl-1,2,3,6-tetrahydropyridin-4-ol including the price, delivery time and more detailed product information at the technical inquiry form on this page

2-Formyl-6-methoxypyridine is a synthetic serine protease inhibitor. It binds to the active site of serine proteases and inhibits their activity by blocking the catalytic triad (Ser, His, Asp). 2-Formyl-6-methoxypyridine has been shown to inhibit the release of inflammatory mediators in mast cells. This drug also inhibits cardiovascular diseases through its ability to reduce cholesterol levels and atherosclerotic plaque formation. The supramolecular complex between 2-formyl-6-methoxypyridine and ruthenium can be used as a fluorescent probe for electrochemical studies. 2-Formyl-6-methoxypyridine has a red shift in its emission spectrum when bound to ruthenium.

Applications 5-Cyclohexyl-2-piperidinecarboxylic Acid is a compound useful in organic synthesis.

6-Amino-5-bromopyridine-2-carboxylic acid methyl ester is an optimisation agent that is used to increase the yield of chemical reactions. It can be used as a modulator in the presence of potassium and has been found to reliably improve the rate of reaction. This compound is an active catalyst for amidation reactions, which are often catalysed by carboxylic acids. 6-Amino-5-bromopyridine-2-carboxylic acid methyl ester is anhydrous and can be stored under a dry inert atmosphere.

((2R,4S)-2-Benzyl-4-((quinolin-4-ylmethyl)amino)piperidin-1-yl)(3,5-dimethylphenyl)methanone is a potent and selective 5HT4 receptor agonist. It has been shown to have antidepressant properties in animal models of depression. ((2R,4S)-2-Benzyl-4-((quinolin-4-ylmethyl)amino)piperidin-1-yl)(3,5-dimethylphenyl)methanone has been shown to increase the release of dopamine in the brain. The effective dose for this drug is low, which may be due to its ability to stimulate dopaminergic activity at the postsynaptic level. ((2R,4S)-2-Benzyl-4-(quinolin(4)-ylethynylamino))piperidin(1)-y))(

6-Methyl-2-thioxo-1,2-dihydropyridine-3-carbonitrile is a quinaldine compound that binds to the DNA of bacteria and inhibits the synthesis of protein. The affinity for 6-methyl-2-thioxo-1,2-dihydropyridine-3-carbonitrile is high, with a constant of 10.6 x 10(-6) M. It has been shown to be potent against other pyridines and interacts with chloroform. The name of this substance is 6Fluoro 3Indoxyl Beta D Galactopyranoside. This product belongs to the class of antituberculosis drugs, Rifamycins and it is one of the most active forms used for treatment of tuberculosis. The drug inhibits bacterial growth by binding to DNA dependent RNA polymerase which prevents transcription and replication. There are many metabolic transformations including hydrolysis by

Please enquire for more information about N-[2-(4-Benzylpiperazin-1-yl)-2-oxoethyl]-N-methylamine including the price, delivery time and more detailed product information at the technical inquiry form on this page

2,3,5-Trimethylpyrazine is a volatile organic compound that is used as an aroma to impart a roasted coffee flavor. It has been shown to be synthesized from the reaction of trimethyl and pyruvic acid in an enzymatic reaction using glutamate pyruvate transaminase. 2,3,5-Trimethylpyrazine can be analyzed by capillary gas chromatography with mass spectrometric detection (GC-MS) or high performance liquid chromatography with mass spectrometric detection (HPLC-MS). This compound can also be identified by its synchronous fluorescence emission spectrum. Analysis of this compound's chemical structure revealed a hydroxyl group on the methyl group and a protocatechuic acid moiety on the pyrazine ring. The presence of these functional groups provides evidence for the model system proposed for this molecule. Solid phase microextraction was used to extract 2,3,5-trimethylpyraz

Applications 2-(pyridin-3-yl)pyrido[2,3-d]pyrimidine has been used in the preparation of divalent transition metal aminonicotinaldehyde chloride complexes, antimicrobial, antioxidant and antitumor activities, electrochemical and molecular docking with EGFR protein. References Konakanchi R., et al., Res. Chem. Intermed., 44, 27-53 (2018)

2-Pyrimidinecarboximidamide HCl is a hydrochloride hemihydrate of 2-amino-4-chloropyrimidine. It crystallizes in the monoclinic system, with space group C2/c and a = 13.997(5), b = 14.871(6), c = 4.921(2) Å, β = 107.068(5)°, V = 848.7(3) Å3, Z = 4. The crystal structure of this compound has been determined by X-ray diffraction analysis of the hydrochloride hemihydrate form at room temperature and found to be consistent with that observed in solution studies.

1-Boc-4-cyclohexylaminopiperidine is a piperidine derivative that is active against Mycobacterium tuberculosis. It has been shown to have good in vitro activity against strains of M. tuberculosis, and although its in vivo efficacy has not yet been determined, it does show potential for the treatment of tuberculosis due to its ability to inhibit mycobacteria growth. 1-Boc-4-cyclohexylaminopiperidine is also able to reduce mycobacterial profiles by modifying their surface proteins. This compound may be effective as an antitubercular agent because it inhibits cell wall synthesis, protein synthesis, and DNA synthesis.

Please enquire for more information about 4-((4-methylphenyl)carbonyl)piperazinecarbaldehyde including the price, delivery time and more detailed product information at the technical inquiry form on this page

1-Propylpiperidin-4-amine 2HCl is a cyclic amine. It is an organic compound that has a high absorption rate and can be used as an absorbent. 1-Propylpiperidin-4-amine 2HCl is used in experiments to study the speciation of different compounds, such as carbonates and desorption. The experiment was performed using various solvents with different densities, such as water, ethanol, and acetone, to determine the absorption rate of 1-Propylpiperidin-4-amine 2HCl. The experiment also studied viscosity changes over time while in contact with 1-Propylpiperidin-4-amine 2HCl. This chemical has a molecular structure consisting of one propyl group and four amines.

Zaleplon metabolite

Please enquire for more information about (2-Methyl-imidazo[1,2-a]pyridin-3-yl)methylamine including the price, delivery time and more detailed product information at the technical inquiry form on this page

Tetrachloro-6-(trichloromethyl)pyridine is a chlorine-containing compound that is a byproduct of the production of chlorofluorocarbons. It is used as an intermediate in the synthesis of other compounds. Tetrachloro-6-(trichloromethyl)pyridine has shown anti-tumor activity against mammary carcinomas, leukemias, and ovarian tumors. This chemical also has been found to be mutagenic with nucleophilic substitution at the pyridine ring. The isomers can be separated using chromatography or gas chromatography. Tetrachloro-6-(trichloromethyl)pyridine can be synthesized from 2,3,4,5-tetrachloropyridine and chlorine gas.

Please enquire for more information about 1-{[2-(4-Isopropylphenyl)-5-methyl-1,3-oxazol-4-yl]methyl}piperidine-4-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

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6-Methoxypyridine-3-sulfonyl chloride (6MP) is an inhibitor that belongs to the class of amides. 6MP has shown potent inhibitory activity against HIV-1 in a variety of assays. It also inhibits protease and transcriptase enzymes, which are necessary for the replication process. 6MP is a derivative of cinnamic acid and can be used as an anti-HIV agent.

Please enquire for more information about (2R,3aR,7aS)-Octahydro-1H-indole-2-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about (1-Methylpiperidin-4-yl)acetonitrile including the price, delivery time and more detailed product information at the technical inquiry form on this page

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3-Chloro-6-(1H-imidazol-1-yl)pyridazine is a potent inhibitor of the enzyme tyrosinase, which is involved in the production of melanin. 3-Chloro-6-(1H-imidazol-1-yl)pyridazine inhibits both mouse and human tyrosinase enzymes with high potency. It has been shown to be selective for mouse tyrosinase over human tyrosinase. The compound has a similar structure to other known inhibitors, making it an excellent starting point for analogs that may have improved potency or selectivity.

5,5-Dimethyltetrahydropyrimidine-2(1H)-thione is a hydrohalide that can be synthesized by reacting the corresponding esters with bromoacetic acid in acetone. The reaction product is anhydrous and has a bicyclic structure. It is used as a reagent for alkylating compounds. 5,5-Dimethyltetrahydropyrimidine-2(1H)-thione reacts with alkyl halides to form esters. It will react with 2 equivalents of ethyl iodide to produce ethyl 5,5-dimethyltetrahydropyrimidine-2(1H)-thione-3(2H)-carboxylate.

Please enquire for more information about N-(4,6-Dimethylpyrimidin-2-yl)-N'-(2-hydroxyphenyl)guanidine including the price, delivery time and more detailed product information at the technical inquiry form on this page

Applications Pyrazine 1,4-Dioxide (cas# 2423-84-9) is a compound useful in organic synthesis. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Please enquire for more information about 1-[(4-Isothiocyanatophenyl)sulfonyl]-3-methylpiperidine including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 1-(2-Hydroxyethyl)piperidine-4-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 4-Oxo-4-(4-(3-phenylprop-2-enyl)piperazinyl)but-2-enoic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 3-Phenyl-Imidazo[1,5-a]pyridine-1-carbaldehyde including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 5-[[[(2,4-Difluorophenyl)methyl]amino]carbonyl]-1-(2,2-dimethoxyethyl)-1,4-dihydro-4-oxo-3-(phenylmethoxy)-2-pyridinecarboxylic acid methyl ester including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 3-(Pyrrolidin-1-ylcarbonyl)piperidine including the price, delivery time and more detailed product information at the technical inquiry form on this page

Applications 2-Hydroxy-4-(trifluoromethyl)pyrimidine (cas# 104048-92-2) is a compound useful in organic synthesis.

Please enquire for more information about 3-(4-Methylpiperidin-1-yl)butanoic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

5-Pyridin-2-yl-1H-pyrazole-3-carboxylic acid is a square, polyhedron, two-dimensional, ferromagnetic molecule with perchlorate anion. It is soluble in water and has a melting point of 208°C. The compound fluoresces in the ultraviolet range and polymerizes in the presence of oxygen. 5-Pyridin-2-yl-1H-pyrazole-3 carboxylic acid has been shown to coordinate as a ligand to metal ions such as iron(III) and copper(II). 5PPY also forms dimers when combined with benzene or pyridine.