Nucléosides
Les nucléosides sont des building blocks fondamentaux des acides nucléiques, composés d'une base azotée attachée à une molécule de sucre. Dans cette section, vous trouverez une large gamme de nucléosides essentiels pour la recherche en biologie moléculaire, biochimie et pharmacologie. Ces composés jouent des rôles cruciaux dans la synthèse de l'ADN et de l'ARN, et sont également vitaux dans divers processus métaboliques. Les nucléosides sont utilisés pour étudier le matériel génétique, développer des thérapies antivirales et anticancéreuses, et comprendre les mécanismes cellulaires. Chez CymitQuimica, nous proposons des nucléosides de haute qualité pour soutenir vos besoins en recherche et développement, garantissant pureté et fiabilité pour vos applications expérimentales.
Produits appartenant à la catégorie "Nucléosides"
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2′-O-Succinyladenosine 3′,5′-monophosphate
CAS :Please enquire for more information about 2′-O-Succinyladenosine 3′,5′-monophosphate including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormule :C14H16N5O9PDegré de pureté :Min. 95%Masse moléculaire :429.28 g/mol2,6-Bis-o-[2-(4-nitrophenyl)ethyl]-2'-deoxyxanthosine
CAS :2,6-Bis-o-[2-(4-nitrophenyl)ethyl]-2'-deoxyxanthosine is a novel nucleotide analog that exhibits anticancer activity. It has been shown to inhibit the growth of human leukemia cells and enhance the cytotoxic effect of doxorubicin. 2,6-Bis-o-[2-(4-nitrophenyl)ethyl]-2'-deoxyxanthosine is a potent inhibitor of DNA synthesis with a high selectivity index for cancer cells. This agent inhibits DNA synthesis by competing with deoxyribonucleosides for incorporation into the growing DNA strand. 2,6-Bis-o-[2-(4-nitrophenyl)ethyl]-2'-deoxyxanthosine is an activator at the adenine phosphoribosyltransferase (APRT) enzyme and may also have an effect on ribonucleotide reductase (RFormule :C26H26N6O9Degré de pureté :Min. 95%Masse moléculaire :566.5 g/mol5'-O-DMT-N2-isobutyryl-2'-O-(2-methoxyethyl)guanosine 3'-CE phosphoramidite
CAS :Nucleoside phosphoramidites are used in the synthesis of oligonucleotides. Using a chemical approach allows quick and inexpensive access to custom-made oligonucleotides of the desired sequence. Enzymatic synthesis proceeds in a 5’ to 3’ direction, however the chemical synthesis is usually performed in the opposite direction. 5'-O-DMT-N2-isobutyryl-2'-O-(2-methoxyethyl)guanosine 3'-CE phosphoramidite, also known as DMT-2'-O-MOE-G(iBu)-CEP, is a modified guanosine with a 2’-O-(2-methoxyethyl) group, these have been used in the synthesis of oligonucleotides as antisense drugs.Formule :C47H60N7O10PDegré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :913.99 g/mol5-Fluorouridine
CAS :5-Fluorouridine, also called 1-(b-D-ribofuranosyl)-5-fluorouracil and 5-fluoro-D-uridine (FUrd), is a modified uridine nucleoside with a fluorine atom at position 5 of the uracil. 5-Fluorouridine is a highly cytotoxic metabolite of 5-fluorouracil, a drug used to treat a variety of cancers, on the market with the trade name Adrucil. Prodrugs of 5-fluorouridine have been investigated for anti-tumour properties in their own right and are close structural analogues of 5'-deoxy-5-fluorouridine, a cytostatic agent in chemotherapy.Formule :C9H11FN2O6Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :262.2 g/molN6-Methyl-N6-threonylcarbamoyladenosine
CAS :N-(N'-Methyl-N-(9 beta-D-ribofuranosylpurin-6-yl)carbamyl)threonine is a nucleoside that is used in research.Formule :C16H22N6O8Degré de pureté :Min. 95%Masse moléculaire :426.38 g/mol3'-Deoxy-N2-DMF-5'-O-DMT-guanosine
CAS :3'-Deoxy-N2-DMF-5'-O-DMT-guanosine is a modified nucleoside that is phosphorylated to the 3'-deoxyribonucleotide form. It has antiviral and anticancer activities, as well as being an activator of DNA and RNA synthesis. This compound has been shown to inhibit the growth of several cancer cell lines in vitro and in vivo. 3'-Deoxy-N2-DMF-5'-O-DMT-guanosine is also effective against herpes simplex virus type 1 (HSV1) and HSV type 2 in cell culture, although it does not have any effect on HSV type 1 replication in animal models.Formule :C34H36N6O6Degré de pureté :Min. 95%Masse moléculaire :624.69 g/mol5’-Deoxy-N4-dimethyl-5-fluorocytidine
CAS :5’-Deoxy-N4-dimethyl-5-fluorocytidine is a novel antiviral agent that inhibits the synthesis of viral RNA. It is synthesized by the de novo purine nucleotide biosynthesis pathway and is activated by phosphorylation to a 5'-diphosphate. This compound has been shown to inhibit the replication of herpes simplex virus type 1 in cell culture. In addition, it has been shown to have anticancer activity against human leukemia cells in vitro and in vivo.Degré de pureté :Min. 95%(E)-Ferulic acid 4-O-β-D-glucoside
CAS :(E)-Ferulic acid 4-O-β-D-glucoside is made up of ferulic acid, which is a natural compound found in things like rice, wheat and oats. Attached to this is a glucose molecule. This product can be used in research and potential be used to study its potential health benefits.Formule :C16H20O9Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :356.32 g/mol5’-Azido-2’,5’-dideoxyuridine
CAS :5’-Azido-2’,5’-dideoxyuridine (5ADU) is a pyrimidine nucleoside that has been used to treat cancer. It is converted to 5-azidouracil which inhibits the synthesis of thymidylate, an essential component of DNA. 5ADU is also active against herpes virus and can be used as an antiviral agent. This drug has been shown to protect against radiation damage by inhibiting the formation of free radicals. The protonation of 5ADU leads to a stereochemical rearrangement that prevents the formation of free radicals. 5ADU does not inhibit bacterial enzymes, but it does have some effect on viruses, such as herpes virus, because they contain DNA or RNA similar to human cells.Formule :C9H11N5O4Degré de pureté :Min. 95%Masse moléculaire :253.21 g/mol2'-Deoxyguanosine-[15N5] monohydrate
CAS :2'-Deoxyguanosine-[15N5] monohydrate is a chemical compound that has been shown to have anticancer activity in colorectal adenocarcinoma cells. The high-activity form of this compound is produced by the addition of a 15N isotope, which can be detected using an electrochemical detector. This compound inhibits the enzyme DNA methyltransferase, preventing the addition of methyl groups to DNA and thereby inhibiting cell growth. 2'-Deoxyguanosine-[15N5] monohydrate also has anti-inflammatory properties due to its ability to inhibit IL-2 receptor signaling.Formule :C10H13N5O4·H2ODegré de pureté :Min. 95%Couleur et forme :White/Off-White SolidMasse moléculaire :285.26 g/mol1-[(5E)-3-O-[(Bis-diisopropylamino)(2-cyanoethoxy) phosphino]-5,6-dideoxy-6-(diethoxyphosphinyl)-2-O-methyl-β-D- ribo-hex-5-enofu ranosyl]uracil
5-Deoxy-2'-O-methylcytidine is a phosphoramidite nucleoside that has antiviral, anticancer, and antifungal properties. It is used as an activator in the synthesis of oligonucleotides and as a reagent for the synthesis of other nucleotide analogues. 5-Deoxy-2'-O-methylcytidine has been shown to have a novel mechanism of action, which targets DNA polymerase alpha and inhibits replication. This drug also has antiangiogenic activity, which may be due to its ability to inhibit the production of VEGF.Degré de pureté :Min. 95%N4-Benzoyl-3'-deoxy-5'-O-DMT-cytidine
CAS :N4-Benzoyl-3'-deoxy-5'-O-DMT-cytidine is a synthetic nucleoside that is used as an activator for DNA synthesis. It is also used in the preparation of diphosphate derivatives for use as antiviral and anticancer agents or as probes for DNA and RNA research. N4-Benzoyl-3'-deoxy-5'-O-DMT-cytidine is a novel, high purity, and high quality chemical with CAS No. 86234-45-9.Formule :C37H35N3O7Degré de pureté :Min. 95%Masse moléculaire :633.69 g/mol2'-Deoxy-5-fluorouridine 5'-monophosphate sodium salt
CAS :2'-Deoxy-5-fluorouridine 5'-monophosphate sodium salt is a prodrug that is converted to fluorouracil in the body. Fluorouracil inhibits the activity of thymidylate synthase and other enzymes involved in DNA synthesis, which are associated with cancer. It is also an inhibitor binding to the enzyme RNA polymerase II, which may contribute to its anti-cancer effects. 2'-Deoxy-5-fluorouridine 5'-monophosphate sodium salt has been shown to inhibit the growth of human tumor cells in culture and in animal models. The matrix effect may be responsible for this activity. 2'-Deoxy-5-fluorouridine 5'-monophosphate sodium salt can be used as a model system for studying cancer tissues.Formule :C9H12FN2O8P·xNaDegré de pureté :Min. 85 Area-%Couleur et forme :White Off-White PowderMasse moléculaire :326.17 g/mol3'-Deoxy-3'-fluoro-isocytidine
3'-Deoxy-3'-fluoro-isocytidine is a nucleoside that belongs to the class of Deoxyribonucleosides. It is a novel nucleoside that has antiviral and anticancer properties. 3'-Deoxy-3'-fluoro-isocytidine inhibits viral replication by inhibiting the action of DNA polymerase. It also inhibits cancer cell proliferation through inhibition of DNA synthesis and protein synthesis, as well as induction of apoptosis. 3'-Deoxy-3'-fluoro-isocytidine is phosphorylated by ribonucleotide reductase in the erythrocyte to yield its active form, deoxycytidine monophosphate (dCMP).Degré de pureté :Min. 95%N6-Benzoyl-2'-deoxy-a-adenosine
N6-Benzoyl-2'-deoxy-a-adenosine is a synthetic nucleoside analog. N6-Benzoyl-2'-deoxy-a-adenosine has antiviral and anticancer properties. It is a potent inhibitor of DNA polymerase and also inhibits ribonucleotide reductase, which are enzymes crucial for DNA synthesis. N6-Benzoyl-2'-deoxy-a-adenosine inhibits the synthesis of viral RNA, leading to inhibition of viral replication. It has been shown to inhibit proliferation of tumor cells in vitro and in vivo by inhibiting DNA synthesis and inducing apoptosis.Formule :C17H17N5O4Degré de pureté :Min. 95%Masse moléculaire :355.36 g/mol8-(2-Amino-1-methyl-D3-6-phenylimidazo[4,5-b]pyridyl-2'-deoxyguanosine
CAS :Produit contrôlé8-(2-Amino-1-methyl-D3-6-phenylimidazo[4,5-b]pyridyl-2'-deoxyguanosine) is a modified nucleoside that is used as an antiviral agent. It is not active against DNA viruses but has been shown to inhibit the replication of RNA viruses such as human immunodeficiency virus type 1 (HIV). 8-(2-Amino-1-methyl-D3-6-phenylimidazo[4,5-b]pyridyl)-2'-deoxyguanosine has been found to be more effective than acyclovir (Zovirax), a commonly used antiviral drug. This nucleoside also has anticancer properties, which may be due to its ability to inhibit the synthesis of DNA and RNA.Formule :C23H20D3N9O4Degré de pureté :Min. 95%Masse moléculaire :492.5 g/mol3’-O-(2-Methoxyethyl)adenosine
CAS :3’-O-(2-Methoxyethyl)adenosine is a nucleoside, a kind of building block for DNA. It is an antiviral agent that inhibits viral replication by preventing the incorporation of viral nucleic acid into host DNA. 3’-O-(2-Methoxyethyl)adenosine also has anticancer properties, which makes it useful as a chemotherapeutic agent. 3’-O-(2-Methoxyethyl)adenosine is synthesized from adenosine monophosphate in two steps: first, the methoxy group is attached to the 2’ position of the ribose sugar by phosphoramidite chemistry; second, the 5' hydroxyl group is oxidized to form the phosphate ester.Formule :C13H19N5O5Degré de pureté :Min. 95%Masse moléculaire :325.32 g/mol5'-O-Acetyl-2'-deoxy-2',2'-difluorocytidine
5'-O-Acetyl-2'-deoxy-2',2'-difluorocytidine is a novel nucleoside that can be used as an antiviral and anticancer agent. It has shown to be more potent than other nucleosides in inhibiting the synthesis of viral DNA and RNA, which makes it a potential candidate for treating HIV infection and cancer. This drug can also act as an activator by stimulating the production of deoxyribonucleotides and ribonucleotides. 5'-O-Acetyl-2'-deoxy-2',2'-difluorocytidine has been shown to have high purity and quality, making it a good candidate for use in various fields of research.Formule :C11H13F2N3O5Degré de pureté :Min. 98 Area-%Couleur et forme :PowderMasse moléculaire :305.23 g/mol5'-O-DMT-thymidine 3'-Rp-oxazaphospholidine
5'-O-DMT-thymidine 3'-Rp-oxazaphospholidine is a novel nucleoside analogue. It has antiviral activity and can be used to treat infections caused by herpes virus. It also has anticancer activity against some types of cancer cells and can inhibit the growth of tumour cells. 5'-O-DMT-thymidine 3'-Rp-oxazaphospholidine acts as an inhibitor of DNA polymerase, preventing the synthesis of DNA from RNA. It also inhibits ribonucleotide reductase, which is involved in the production of ribonucleotides from diphosphate nucleotides. This drug can be used as a monophosphate or phosphoramidite for the synthesis of oligodeoxyribonucleotides and deoxyribonucleotides.Degré de pureté :Min. 95%N4-Benzoyl-1-(2'-deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)cytosine-3'-O-succinate triethylammonium salt
N4-Benzoyl-1-(2'-deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)cytosine is a novel nucleoside that is synthesized from the corresponding deoxyribonucleoside and succinic acid. N4-Benzoyl-1-(2'-deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)cytosine has antiviral activity against DNA viruses and anticancer activity against tumor cells. It has been shown to inhibit the replication of HIV, influenza A virus, and herpes simplex virus type 1 (HSV1).Degré de pureté :Min. 95%
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