Enzymes dans les Protéines Recombinantes

AK3L1 Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag.

ENTPD5 Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with His tag.

Ribonuclease 3 (RNASE3) is a basic protein that is localized to the eosinophil primary matrix and belongs to the pancreatic ribonuclease family.

Catalyzes the NAD-dependent oxidation of all-trans-retinol and its derivatives such as all-trans-4-hydroxyretinol and may participate in retinoid metabolism.

ASAH1 Protein, Mouse, Recombinant (GST & His & Myc) is expressed in E.

STEAP2 Protein, Human, Recombinant (His) is expressed in in vitro E. coli expression system with N-10xHis. The accession number is Q8NFT2.

Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway.

USP18 Protein, Human, Recombinant (His) is expressed in E.

Hyaluronidase (EC 3.2.1.35) is an enzyme that cleaves (1→4)-linkages between N-acetylglucosamine and glucuronate. One unit of hyaluronidase will increase turbidimetric absorbance at A600 by 0.330 at pH 5.7 and 37°C in 2mL reaction volume.

Catalyzes the depolymerization of alginate by cleaving the beta-1,4 glycosidic bond between two adjacent sugar residues via a beta-elimination mechanism.

SULT1A3 belongs to the sulfotransferase 1 family.

Regulates pathways leading to the activation of NF-kappa-B and MAP kinases, and plays a central role in the regulation of B-cell survival.

Tyrosine kinase of the non-receptor type, involved in the IFN-alpha/beta/gamma signal pathway.

Ubiquitin-Conjugating Enzyme E2 (UBE2A) is a member of the E2 Ubiquitin-Conjugating Enzyme family.

Responsible for the post-translational oxidative deamination of peptidyl lysine residues in precursors to fibrous collagen and elastin.

USP7 Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag.

METAP2 Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with His tag.

IL-1RAPL1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.

LIPF Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag.

ABO (ABO, Alpha 1-3-N-Acetylgalactosaminyltransferase And Alpha 1-3-Galactosyltransferase) is a Protein Coding gene.

Opens the cyclic ring of dihydroxy-phenylalanine (DOPA) between carbons 4 and 5, thus producing an unstable seco-DOPA that rearranges nonenzymatically to

N/A.

Bromelain is a group of proteolytic enzymes found in the fruit and stem of pineapple plants. It is used in a topical drug product approved by the FDA to treat severe burns. However, its oral consumption to treat sinusitis, postoperative pain after the extraction of wisdom teeth, and osteoarthritis is still being researched.

CYP2A6 Protein, Human, Recombinant (His & Myc) is expressed in E. coli.

Thiol protease which is believed to participate in intracellular degradation and turnover of proteins.

Protein kinase LATS2 is a serine/threonine kinase, which is a crucial component sourced intrinsically from cellular kinase cascades involved in cell regulation. This protein kinase is pivotal in the Hippo signaling pathway, which regulates cell growth, apoptosis, and stem cell renewal. LATS2 is part of the core kinase cascade that, upon activation, phosphorylates and inhibits the activity of the transcriptional co-activators YAP and TAZ, thereby controlling their transcriptional activity. This inhibition is key to maintaining proper cell proliferation and preventing uncontrolled cell growth that could lead to tumorigenesis. LATS2 is extensively studied for its role in cancer biology as its dysregulation is often linked to various cancers. Beyond oncology, its contributions to developmental biology and tissue homeostasis are significant. Research into LATS2 not only enhances our understanding of cell cycle control and development but also aids in the potential design of therapeutic interventions targeting the Hippo pathway in cancer and regenerative medicine.

Catalase (CAT) is a member of the catalase family.

F10, also known as Coagulation factor X, belongs to the peptidase S1 family that is synthesized as a 488 amino acid (aa) with a signal peptide and a pro region

Mutc Protein, Mouse, Recombinant (His) is expressed in E. coli.

Ectonucleotide pyrophosphatase/phosphodiesterase (ENPP)-1 is a membrane-bound protein that catalyzes the hydrolysis of extracellular nucleoside triphosphates to

Cytosolic beta-glucosidase, also known as Cytosolic beta-glucosidase-like protein 1, GBA3, CBG and CBGL1 is a cytoplasm protein which belongs to theglycosyl

Carbonic Anhydrase 9 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.

Mediates the proteolytic cleavage of HP/haptoglobin in the endoplasmic reticulum.

A proteolytic enzyme; degrades protein contaminants in nucleic acid preparations

Lipases belong to the family of esterases and naturally act on triglycerides at lipid-water interfaces. Lipases/esterases can be used as versatile tools in hydrolytic reactions, esterifications and transesterification reactions in industrial and food applications. The CalB02 ICE lipase has been immobilized on a hydrophobic carrier by a covalent linkage. The immobilized CalB02 lipase has a temperature optimum in the 40 - 50 °C range and pH optimum between pH 5 and 8.

Uroporphyrinogen decarboxylase (UROD), is an enzyme of the heme biosynthetic pathway which belongs to the uroporphyrinogen decarboxylase family.

SPO11 Protein, Human, Recombinant (E. coli, His) is expressed in E. coli with C-6xHis. The accession number is Q9Y5K1.

Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).

Papain Protein, Carica papaya, Recombinant (His) is expressed in E.

PLA2G15 Protein, Canine, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag.

Citrate lyase (also known as ATP citrate synthase, EC 2.3.3.8) is an enzyme that catalyzes the following reaction:citrate + ATP + CoA → oxaloacetate + Acetyl-CoA + ADP + PiEnzymatic activity: One unit will convert 1.0 micromole of citrate to oxalacetate per minute at pH 7.6 and 25 °C in the presence of required cofactors. Citrate lyase is supplied lyophylized, with activity ≥0.20 unit/mg solid.

Acts against tyrosine-phosphatases.

Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP.

Pegloticase is a PEGylated urate oxidase enzyme used to treat chronic granulomatous disease. It is also a methyltransferase inhibitor that prevents the activation of bacterial enzymes, such as cytosine-guanine dinucleotide phosphate (CpG) methyltransferase. This enzyme catalyses the methylation of CpG sites on DNA, which are important for maintaining normal gene expression. Pegloticase has been shown to be effective in reducing the activity of inflammatory bowel disease and rheumatoid arthritis. It also has been shown to have pharmacological effects on congestive heart failure, hypersensitivity syndrome, and bowel diseases due to its anti-inflammatory properties. Pegloticase has not been studied in patients with hepatic impairment or taking nonsteroidal anti-inflammatory drugs.

TLK2 Protein, Human, Recombinant (aa 397-772, His & GST) is expressed in Baculovirus insect cells with His and GST tag.

KDM6B Protein, Human, Recombinant (His) is expressed in E. coli with C-6xHis. The accession number is O15054.

Cathepsin B Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.

FUCA1 is a lysosomal enzyme involved in the degradation of fucose-containing glycoproteins and glycolipids.

Aldose reductase (AKR1B1) belongs to the aldo/keto reductase superfamily.

Diacylglycerol kinase that converts diacylglycerol/DAG into phosphatidic acid/phosphatidate/PA and regulates the respective levels of these two bioactive lipids

DegP acts as a chaperone at low temperatures but switches to a peptidase (heat shock protein) at higher temperatures.

ALDH1A3 Protein, Mouse, Recombinant (His) is expressed in E.

ENTPD3 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag.

PDE9A Protein, Human, Recombinant (His & Myc) is expressed in E. coli.

Endoproteinase Glu-C (Glutamyl endopeptidase, V8 protease, GluV8, EC 3.4.21.19) is a protease that hydrolyzes peptide bonds at the carboxylic side of either exclusively Glu, or Glu and Asp residues, depending on the buffer conditions. One unit of endoproteinase Glu-C will generate 1.0 μmole of p-nitroaniline from Z-Phe-Leu-Glu-pNA peptide mimic substrate per minute at pH 7.8 and 25 °C. Z-Phe-Leu-Glu-pNA substrate is available here.molecular weight ~ 27000.

HTRA1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 50.50 kDa and the accession number is Q92743.

This protein functions as a defense against chitin-containing fungal pathogens.

FKBP12 Protein, Mouse, Recombinant (His) is expressed in E.

Ribonuclease MC Protein, Momordica charantia, Recombinant (His & Myc) is expressed in E.

HINT1 Protein, Rabbit, Recombinant (His & Myc) is expressed in HEK293 mammalian cells with N-10xHis and C-Myc tag.

Dual specificity protein kinase CLK3, also known as CDC-like kinase 3, and CLK3, is a member of CMGC Ser/Thr protein kinase family and Lammer subfamily.

Carbonic Anhydrase 2 Protein, Mouse, Recombinant (His) is expressed in E.

AOAH Protein, Human, Recombinant (His) is expressed in E. coli with C-6xHis. The accession number is P28039.

P4HA1 Protein, Human, Recombinant (His) is expressed in E. coli.

ErbB4 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.

PTGS2, also known as COX-2, is s component of Prostaglandin-endoperoxide synthase (PTGS).

Protease that has a low substrate specificity.

E2 conjugating enzyme that associates with the E3 ubiquitin-protein ligase EL5 to mediates ubiquitination of target proteins.

PML Protein, Human, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag.

FNDC4 acts as an anti-inflammatory factor on macrophages and improves mouse model of induced colitis.

Cleaves collagen, gelatin, casein, alpha-1-antitrypsin, and bovine insulin. May play a role in the pathogenesis of legionnaires disease.

ARSA Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.

Removes the formyl group from the N-terminal Met of newly synthesized proteins.

Lipase 09 recombinantly expressed in E. coli comes in a spray-dried formulation. It has its pH optimum at 7 and temp. optimum at 35-55°C. Lipases belong to the family of esterases and naturally act on triglycerides at lipid-water interfaces catalyzing hydrolytic reactions, esterifications and transesterification reactions in industrial and food applications. Lipase 09 was shown to hydrolyze p-Nitrophenyl esters of acetate (18 % activity compared to octanoate), butyrate (80 %), octanoate (100 %) and capate (40 %).

Ectonucleotide pyrophosphatase-phosphodiesterase 3 (ENPP3), a protein detected in the human uterus, has been found to play an important role in the development

Proteinase, Bacillus subtilis, sutilain is a proteolytic enzyme, which is derived from the bacterium Bacillus subtilis. This enzyme exhibits a serine-type mechanism of action, characterized by its ability to cleave peptide bonds in proteins efficiently. It catalyzes the hydrolysis of proteins into peptides and amino acids, facilitating the breakdown of complex proteins into simpler, soluble forms. The uses and applications of Proteinase, Bacillus subtilis, sutilain are diverse due to its robust proteolytic capabilities. It is widely employed in various industrial processes, including the food and detergent industries, where it aids in the breakdown of proteinaceous materials. In the pharmaceutical and research sectors, it is utilized for protein digestion in peptide mapping, protein sequencing, and in the preparation of protein hydrolysates for nutritional and therapeutic purposes. Its stability under a range of conditions makes it a versatile tool for laboratory and industrial settings, enabling advances in protein engineering and bioprocess optimization.

(R)-Mandelonitrile lyase (systematic name mandelonitrile benzaldehyde-lyase (hydrogen cyanide-forming), other names are D-oxynitrilase, D-alpha-hydroxynitrile lyase, (R)-oxynitrilase, oxynitrilase, mandelonitrile benzaldehyde-lyase, ydroxynitrile lyase; EC 4.1.2.10) is the enzyme that catalyzes the following reaction:mandelonitrile ⇌ hydrogen cyanide + benzaldehydeOne unit of (R)-mandelonitrile lyase will convert 1.0 μmol of mandelonitrile per minute under optimal conditions.

Please enquire for more information about Phosphorylase B from rabbit muscle including the price, delivery time and more detailed product information at the technical inquiry form on this page

PCSK9 Protein, Human, Recombinant (His) is expressed in HEK293 Cells. The predicted molecular weight is 73.03 kDa and the accession number is Q8NBP7.

Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of double-stranded RNA (dsRNA), single-stranded RNA (ssRNA), double stranded DNA (dsDNA) and

NADP-ME Protein, Human, Recombinant (His) is expressed in E.

Maltose phosphorylase (systematic name maltose:phosphate 1-beta-D-glucosyltransferase; EC 2.4.1.8) is an enzyme that catalyzes the following reaction:  maltose + Pi ⇌ D-glucose + beta-D-glucose 1-phosphate  One unit of maltose phosphorylase will produce 1.0 μmole of D-Glucose from maltose per minute at pH 7.0 and 30°C.

PSMB8 Protein, Human, Recombinant (His & Myc & SUMO) is expressed in E. coli.

LARGE1 Protein, Human, Recombinant (His) is expressed in E. coli with C-6xHis. The accession number is O95461.

Cyclin-dependent kinase-like 2 (Cdkl2) is a member of cdc2-related serine / threonine protein kinase family and it is found expressed in various brain regions,

FTCD Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag.

May be involved in cell growth.

May be involved in the proteolytic inactivation of enkephalins and neurotensin in some brain areas.

The cAMP-dependent protein kinase PKA is a well-characterized member of the serine-threonine protein AGC kinase family and is the effector kinase of cAMP

GBA Protein, Mouse, Recombinant (His & SUMO) is expressed in E. coli.

PLK1 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag.

DNA polymerase is an essential enzymatic protein, derived from various organisms including bacteria, archaea, and eukaryotes, which plays a pivotal role in the replication and repair of DNA. This enzyme functions by adding nucleotides to the growing DNA strand in a template-dependent manner, ensuring the accurate duplication of the genetic material. It operates through a polymerization mechanism, where nucleotides are selected and incorporated complementary to the template strand, facilitating the elongation of the new DNA strand in the 5' to 3' direction. In the laboratory, DNA polymerase is utilized extensively in molecular biology applications, such as polymerase chain reaction (PCR) for amplifying specific DNA sequences, DNA sequencing, and various cloning techniques. Its high fidelity and efficiency make it indispensable for research in genetics, biotechnology, and diagnostics, enabling the detailed examination and manipulation of genetic material. Understanding and exploiting the characteristics of different DNA polymerases, including their temperature stability and proofreading capability, is crucial for tailoring their use to specific experimental requirements.

Catalyzes the conversion of L-arabinose to L-ribulose.

Matrix metalloproteinase 9 (MMP9) contributes to this process and deficiencies in the MMP9 lead to impaired healing.

Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.

GSTT2B Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.

N/A.

TrkB Protein, Canine, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.

Porcine liver esterase (EC 3.1.1.1) is an enzyme that catalyses ester hydrolysis, producing a fatty acid and an alcohol. One unit of esterase will hydrolyze 1.0 μmole of ethyl butyrate to butyric acid and ethanol per min at pH 8.0 and 25 °C. Ethyl butyrate is available here.

Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for