Enzymes dans les Protéines Recombinantes

AK3L1 Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag.

ENTPD5 Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with His tag.

Ribonuclease 3 (RNASE3) is a basic protein that is localized to the eosinophil primary matrix and belongs to the pancreatic ribonuclease family.

Catalyzes the NAD-dependent oxidation of all-trans-retinol and its derivatives such as all-trans-4-hydroxyretinol and may participate in retinoid metabolism.

ASAH1 Protein, Mouse, Recombinant (GST & His & Myc) is expressed in E.

STEAP2 Protein, Human, Recombinant (His) is expressed in in vitro E. coli expression system with N-10xHis. The accession number is Q8NFT2.

Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway.

USP18 Protein, Human, Recombinant (His) is expressed in E.

Hyaluronidase (EC 3.2.1.35) is an enzyme that cleaves (1→4)-linkages between N-acetylglucosamine and glucuronate. One unit of hyaluronidase will increase turbidimetric absorbance at A600 by 0.330 at pH 5.7 and 37°C in 2mL reaction volume.

Catalyzes the depolymerization of alginate by cleaving the beta-1,4 glycosidic bond between two adjacent sugar residues via a beta-elimination mechanism.

SULT1A3 belongs to the sulfotransferase 1 family.

Regulates pathways leading to the activation of NF-kappa-B and MAP kinases, and plays a central role in the regulation of B-cell survival.

Tyrosine kinase of the non-receptor type, involved in the IFN-alpha/beta/gamma signal pathway.

Ubiquitin-Conjugating Enzyme E2 (UBE2A) is a member of the E2 Ubiquitin-Conjugating Enzyme family.

Responsible for the post-translational oxidative deamination of peptidyl lysine residues in precursors to fibrous collagen and elastin.

USP7 Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag.

METAP2 Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with His tag.

IL-1RAPL1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.

LIPF Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag.

ABO (ABO, Alpha 1-3-N-Acetylgalactosaminyltransferase And Alpha 1-3-Galactosyltransferase) is a Protein Coding gene.

Opens the cyclic ring of dihydroxy-phenylalanine (DOPA) between carbons 4 and 5, thus producing an unstable seco-DOPA that rearranges nonenzymatically to

N/A.

Bromelain is a group of proteolytic enzymes found in the fruit and stem of pineapple plants. It is used in a topical drug product approved by the FDA to treat severe burns. However, its oral consumption to treat sinusitis, postoperative pain after the extraction of wisdom teeth, and osteoarthritis is still being researched.

CYP2A6 Protein, Human, Recombinant (His & Myc) is expressed in E. coli.

Thiol protease which is believed to participate in intracellular degradation and turnover of proteins.

Protein kinase LATS2 is a serine/threonine kinase, which is a crucial component sourced intrinsically from cellular kinase cascades involved in cell regulation. This protein kinase is pivotal in the Hippo signaling pathway, which regulates cell growth, apoptosis, and stem cell renewal. LATS2 is part of the core kinase cascade that, upon activation, phosphorylates and inhibits the activity of the transcriptional co-activators YAP and TAZ, thereby controlling their transcriptional activity. This inhibition is key to maintaining proper cell proliferation and preventing uncontrolled cell growth that could lead to tumorigenesis. LATS2 is extensively studied for its role in cancer biology as its dysregulation is often linked to various cancers. Beyond oncology, its contributions to developmental biology and tissue homeostasis are significant. Research into LATS2 not only enhances our understanding of cell cycle control and development but also aids in the potential design of therapeutic interventions targeting the Hippo pathway in cancer and regenerative medicine.

Catalase (CAT) is a member of the catalase family.

F10, also known as Coagulation factor X, belongs to the peptidase S1 family that is synthesized as a 488 amino acid (aa) with a signal peptide and a pro region

Mutc Protein, Mouse, Recombinant (His) is expressed in E. coli.

Ectonucleotide pyrophosphatase/phosphodiesterase (ENPP)-1 is a membrane-bound protein that catalyzes the hydrolysis of extracellular nucleoside triphosphates to

Cytosolic beta-glucosidase, also known as Cytosolic beta-glucosidase-like protein 1, GBA3, CBG and CBGL1 is a cytoplasm protein which belongs to theglycosyl

Carbonic Anhydrase 9 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.

Mediates the proteolytic cleavage of HP/haptoglobin in the endoplasmic reticulum.

A proteolytic enzyme; degrades protein contaminants in nucleic acid preparations

Lipases belong to the family of esterases and naturally act on triglycerides at lipid-water interfaces. Lipases/esterases can be used as versatile tools in hydrolytic reactions, esterifications and transesterification reactions in industrial and food applications. The CalB02 ICE lipase has been immobilized on a hydrophobic carrier by a covalent linkage. The immobilized CalB02 lipase has a temperature optimum in the 40 - 50 °C range and pH optimum between pH 5 and 8.

Uroporphyrinogen decarboxylase (UROD), is an enzyme of the heme biosynthetic pathway which belongs to the uroporphyrinogen decarboxylase family.

SPO11 Protein, Human, Recombinant (E. coli, His) is expressed in E. coli with C-6xHis. The accession number is Q9Y5K1.

Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).

Papain Protein, Carica papaya, Recombinant (His) is expressed in E.

PLA2G15 Protein, Canine, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag.

Citrate lyase (also known as ATP citrate synthase, EC 2.3.3.8) is an enzyme that catalyzes the following reaction:citrate + ATP + CoA → oxaloacetate + Acetyl-CoA + ADP + PiEnzymatic activity: One unit will convert 1.0 micromole of citrate to oxalacetate per minute at pH 7.6 and 25 °C in the presence of required cofactors. Citrate lyase is supplied lyophylized, with activity ≥0.20 unit/mg solid.

Acts against tyrosine-phosphatases.

Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP.

Pegloticase is a PEGylated urate oxidase enzyme used to treat chronic granulomatous disease. It is also a methyltransferase inhibitor that prevents the activation of bacterial enzymes, such as cytosine-guanine dinucleotide phosphate (CpG) methyltransferase. This enzyme catalyses the methylation of CpG sites on DNA, which are important for maintaining normal gene expression. Pegloticase has been shown to be effective in reducing the activity of inflammatory bowel disease and rheumatoid arthritis. It also has been shown to have pharmacological effects on congestive heart failure, hypersensitivity syndrome, and bowel diseases due to its anti-inflammatory properties. Pegloticase has not been studied in patients with hepatic impairment or taking nonsteroidal anti-inflammatory drugs.

TLK2 Protein, Human, Recombinant (aa 397-772, His & GST) is expressed in Baculovirus insect cells with His and GST tag.

KDM6B Protein, Human, Recombinant (His) is expressed in E. coli with C-6xHis. The accession number is O15054.

Cathepsin B Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.

FUCA1 is a lysosomal enzyme involved in the degradation of fucose-containing glycoproteins and glycolipids.

Aldose reductase (AKR1B1) belongs to the aldo/keto reductase superfamily.

Diacylglycerol kinase that converts diacylglycerol/DAG into phosphatidic acid/phosphatidate/PA and regulates the respective levels of these two bioactive lipids