Enzymes dans les Protéines Recombinantes

LDHA Protein, Rat, Recombinant (His) is expressed in E.

Adenosine deaminase catalyzes deamination of adenosine, converting it to inosine. It happens by the substituting of the amino group by a keto group. One Unit of the enzyme converts one micromole of adenosine to inosine per minute at 25°C, pH 7.4. Adenosine deaminase is also known by names of adenosine aminohydrolase, and ADA, EC 3.5.4.4.

ADAM8/CD156a Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.

ALDH1A1 Protein, Mouse, Recombinant (E. coli, His) is expressed in E. coli with N-6xHis. The accession number is P24549.

Transcriptional coactivator that interacts with numerous nuclear receptors and coactivators and modulates the transcription of target genes.

MDM2 Protein, Mouse, Recombinant (His) is expressed in E.

Human Sulfatase Modifying Factor 1 (SUMF1) is a 42kDa protein.

G protein-coupled receptor kinase 5, also known as G protein-coupled receptor kinase GRK5 and GRK5, is a member of the protein kinase superfamily, AGC Ser/Thr

Carbonic Anhydrase 14 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 Cells. The accession number is Q9ULX7.

Sulfotransferase family cytosolic 1B member 1, also known as Sulfotransferase 1B1, Sulfotransferase 1B2, Thyroid hormone sulfotransferase, SULT1B1 and ST1B2, is

RNF182 Protein, Human, Recombinant (E. coli, His) is expressed in E. coli with C-6xHis. The accession number is Q8N6D2.

B3GNT2 belongs to the beta-1,3-N-acetylglucosaminyltransferase family.

FLT1 Protein, Human, Recombinant (aa 1-328, His) is expressed in HEK293 mammalian cells with His tag.

Peroxidases can be utilized as enzymes catalyzing e.g. aromatic ring hydroxylation, epoxidation, halogenation, N- or S-oxidation, ether cleavage and alcohol/aldehyde oxidation reactions.

Angiogenin belongs to the pancreatic ribonuclease family.

Histone-lysine N-methyltransferase SETD7, also known as SET domain containing (lysine methyltransferase) 7, SET7/9, Histone H3-K4 methyltransferase SETD7, H3-K4

Plasma membrane-anchored serine protease that participates in proteolytic cascades of relevance for the normal physiologic function of the prostate.

RPS3 Protein, Human, Recombinant (His) is expressed in E.

Protein-arginine deiminase type-4, also known as HL-6 PAD, Peptidylarginine deiminase IV, Protein-arginine deiminase type I V and PADI4, is a cytoplasm and

The papain superfamily member bleomycin hydrolase (BLMH) is a cytoplasmic cysteine peptidase that is highly conserved through evolution.

CBS Protein, Human, Recombinant (His) is expressed in Yeast.

Genetic engineers have used glutathione S-transferase to create the GST gene fusion system.

Guanylyl cyclase C (GUCY2C) has canonical centrality in defense of key intestinal homeostatic mechanisms, encompassing fluid and electrolyte balance, epithelial

RIPK3 Protein, Mouse, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 54.8 kDa and the accession number is Q9QZL0.

The recycling of citrulline by argininosuccinate synthase 1 (ASS1) and argininosuccinate lyase (ASL) is crucial to maintain arginine availability and nitric

PARP9 Protein, Human, Recombinant (His & Myc) is expressed in HEK293.

During the asexual blood stage, participates in initial cleavage of native host hemoglobin (Hb) resulting in Hb denaturation.

ENPP2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.

Carbonic Anhydrase 4 Protein, Human, Recombinant (His), Biotinylated is expressed in CHO Stable Cells. The accession number is P22748-1.

PPIL2, is an enzyme that belongs to the cyclophilin family.

Catalyst for signal development in immunoassays

Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium.

MAPKAPK5 contains 1 protein kinase domain and belongs to the protein kinase superfamily, CAMK Ser/Thr protein kinase family.

Alkaline phosphatase can be considered "our favorite enzyme" for reasons apparent to those who diagnose and treat metabolic bone diseases or who study skeletal

Staphopain A Protein, S.

Lipases belong to the family of esterases and naturally act on triglycerides at lipid-water interfaces. Lipases/esterases can be used as versatile tools in hydrolytic reactions, esterifications and transesterification reactions in industrial and food applications.

PAIRED PRODUCTS AVAILABLE: 4-MU-alpha-L-idopyranosiduronic acid 2-sulphate, Substrate, EM03201 4MU-alpha-L-idopyranosiduronic acid, Substrate, EM04841   Alpha-L-iduronidase is a glycoside hydrolase that cleaves the non-reducing, terminal alpha-L-iduronic acid residues from polysaccharides and oligosaccharides. Alpha-L-iduronidase is involved in the lysosomal degradation of glycosaminoglycans and its deficiency leads to the accumulation of dermatan sulphate and heparan sulphate in tissues, a condition known as mucopolysaccharidosis I (MPS I). Alpha-L-iduronidase activity can be detected and quantified in an assay using a fluorogenic substrate 4MU-alpha-L-idopyranosiduronic acid. Alpha-L-iduronidase is also used in a 2-step assay for Hunter syndrome (MPS II) testing in combination with 4-MU-alpha-L-idopyranosiduronic acid 2-sulphate. This enzyme is supplied as a lyophilisate of: 25% (w/w) Iduronidase enzyme (protein), 37% (w/w) sucrose, 38% (w/w) MOPS potassium (buffer, pH 7.4). The enzyme is derived from a bacterial source, recombinantly expressed in Escherichia coli (see application notes for more details). Alpha-L-iduronidase is also available as an aqueous solution (FI179383)

Cellulose catalase is an enzyme-based product, designed specifically to act as a catalyst in the oxidative processes associated with cellulose applications. It is derived from a microbial source, where bacilli or fungi are employed to produce robust catalase enzymes in a fermentation process. The mode of action involves the catalase enzyme’s ability to facilitate the decomposition of hydrogen peroxide into water and oxygen, thereby reducing oxidative damage during cellulose processing. Cellulose catalase finds extensive use in the textile and paper industries, where it is integral in the bleaching and de-inking processes. By catalyzing the breakdown of hydrogen peroxide, it ensures more efficient and safer removal of residual peroxide, promoting environmentally friendly practices. This biologically mediated reaction not only enhances the quality of cellulose-based products but also minimizes the need for chemical treatments. Moreover, its application extends to the improvement of fiber strength and brightness, establishing it as a crucial tool in sustainable industrial operations.

Involved in protein export.

Has aminoprocollagen type I processing activity in the absence of ADAMTS2.

RAB27B Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 24.3 kDa and the accession number is O00194.

Poly(ADP-ribose) glycohydrolase is an enzyme, which is derived from various organisms, including eukaryotic cells. It plays a crucial role in the regulation of poly(ADP-ribose) (PAR) metabolism. This enzyme functions by hydrolyzing the glycosidic bonds in poly(ADP-ribose) chains, thereby regulating the cellular levels of PAR by converting it back to ADP-ribose units. Poly(ADP-ribose) glycohydrolase is significantly involved in DNA repair processes and cellular stress responses. PAR chains are primarily synthesized in response to DNA damage and play an integral role in recruiting and modulating the activity of repair proteins. By controlling the turnover of these PAR chains, Poly(ADP-ribose) glycohydrolase maintains cellular homeostasis and facilitates efficient DNA repair. This regulatory mechanism is essential for maintaining genomic stability and preventing pathological conditions such as cancer. Applications of this enzyme extend to research in DNA repair mechanisms, cell death pathways, and the development of therapeutic strategies targeting PAR metabolism. Understanding its function and manipulation can provide insights into cancer treatment and neurodegenerative diseases, where PAR metabolism is often dysregulated.

beta-Galactosidase (EC 3.2.1.23, shortly beta-Gal, also know as lactase) catalyses the hydrolysis of beta-d-galactoside in the presence of water to galactose and alcohol, or lactose into glucose and galactose. beta-Gal has a molecular weight of 540,000 and is composed of four identical subunits of MW 135,000, each with an independent active site. The enzyme has divalent metals as cofactors, with chelated Mg2+ ions required to maintain active site conformation. The molecule contains numerous sulfhydryl groups and is glycosylated. This type of enzyme is found widespread in many microorganisms, plants and animals. In E. coli for instance, the beta-Gal protein is encoded by the lacZ gene. The enzyme is often used as a reporter for monitoring gene expression. beta-Gal also has good characteristics when conjugated to antibody molecules or streptavidin for use in ELISA kits. In addition, the enzyme is used to determine lactose in biological fluids and it is employed in food processing operations. Traditionally, beta-Gal activity is tested using the X-Gal or ONPG chromogenic substrates. But with the pioneering AquaSpark® beta-D-galactoside a substrate for beta-Gal detection becomes available that provides a previously unseen sensitivity. See here for futher informaiton on AquaSpark®: AquaSpark Chemiluminescence | Cymit Quimica

Sulfotransferase 4A1 (ST4A1) is a member of the Sulfotransferase 1 family.

B3GALT5 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.

Thiol protease involved in osteoclastic bone resorption and may participate partially in the disorder of bone remodeling.

3-Oxo-5β-steroid Δ4-dehydrogenase is an enzyme crucial in the metabolic pathway of steroid hormones, facilitating the conversion of androgens and estrogens. It is predominantly found in the liver, but also in other tissues where steroid biosynthesis occurs. This enzyme catalyzes the dehydrogenation at the Δ4 position of 3-oxo-5β-steroids, playing a significant role in the modulation and regulation of steroid hormone levels within cells. The enzyme functions by oxidizing the Δ4 double bond in the steroid structure, which is a critical step in the conversion of active steroids to their inactive metabolites. This action helps maintain a balance in hormone levels, preventing excessive accumulation of potentially biologically active steroids. In scientific research, understanding and manipulating the activity of 3-Oxo-5β-steroid Δ4-dehydrogenase can offer insights into disorders related to steroid metabolism, such as endocrine imbalances and certain cancers. Additionally, studying this enzyme can advance therapeutic strategies that target steroid-related diseases by modulating enzyme activity or expression. Its application extends to pharmaceutical research, where it can be used to evaluate the metabolic profiles of novel steroid-based drugs.

AK3L1 Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 25.3 kDa and the accession number is P27144-1.

Accepts electrons from ETF and reduces ubiquinone.

Alkaline phosphatase can be considered "our favorite enzyme" for reasons apparent to those who diagnose and treat metabolic bone diseases or who study skeletal

Aspartate β-hydroxylase (ASPH) is silent in normal adult tissues only to re-emerge during oncogenesis where its function is required for generation and

RRM1 is a subunit of ribonucleoside-diphosphate reductase which is constituted by two subunits.

LDHA Protein, Mouse, Recombinant (His) is expressed in E.

KLK3 (Kallikrein Related Peptidase 3) is a Protein Coding gene.

N/A.

Pancreatin is an enzyme preparation, which is derived from the porcine pancreas. This product contains a mixture of several digestive enzymes, including amylase, lipase, and protease. It is typically obtained through the extraction and purification of these enzymes from the pancreas of pigs, providing a natural and effective source for enzymatic activity. The mode of action of pancreatin involves the breakdown of macronutrients in the digestive tract. Amylase catalyzes the hydrolysis of starch into sugars, lipase aids in the digestion of fats by breaking them down into fatty acids and glycerol, and protease facilitates the decomposition of proteins into peptides and amino acids. These actions collectively enhance the digestive process, optimizing nutrient absorption. Pancreatin is used extensively in scientific research and clinical settings to study digestive processes and enzyme deficiencies. It is also utilized in various pharmaceutical formulations aimed at treating conditions like pancreatitis and cystic fibrosis, where there is an insufficiency of natural digestive enzymes. Its broad application in both therapeutic and experimental contexts underlines its significance as a versatile biotechnological product.

Protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral.

MAT2A Protein, Human, Recombinant (His) is expressed in Yeast.

HIBADH Protein, Human, Recombinant (His & Myc) is expressed in E.

Catalyzes the phosphorylation of dihydroxyacetone.

Thrombin-like snake venom serine protease.

GSTA1 Protein, Rat, Recombinant (His & SUMO) is expressed in E. coli.

Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

Mannosyltransferase involved in adding the 4th and 5th mannose residues of O-linked glycans.

Lipases belong to the family of esterases and naturally act on triglycerides at lipid-water interfaces. Lipases/esterases can be used as versatile tools in hydrolytic reactions, esterifications and transesterification reactions in industrial and food applications. The Lipase kit contains 25 lipases with different pH and temperature optima and substrate specificity properties.

Endoplasmic reticulum chaperone that plays a key role in protein folding and quality control in the endoplasmic reticulum lumen.

Non-receptor tyrosine kinase indispensable for B lymphocyte development, differentiation and signaling.

PRSS56 Protein, Human, Recombinant (His & Myc) is expressed in E. coli.

Oxidative stress-responsive 1 protein (OXSR1), also known as Serine/threonine-protein kinase OSR1, is a member of the Ser/Thr protein kinase family of proteins.

ATG1 Protein, Candida glabrata, Recombinant (His) is expressed in E.

Vascular adhesion protein-1(VAP-1) is a copper amine oxidase with a topaquinone cofactor.VAP-1 is a type II integral membrane protein, but a soluble form of the

PRMT5 Protein, Human, Recombinant (Flag & His) is expressed in Baculovirus-Insect Cells. The accession number is O14744-1.

MSRB3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.

PHYH belongs to the family of iron(II)-dependent oxygenases, which typically incorporate one atom of dioxygen into the substrate and one atom into the succinate

CDK4 is a member of the Ser/Thr protein kinase family.

Prostate-specific membrane antigen (PSMA) is an enzyme that in humans is encoded by the FOLH1 (folate hydrolase 1) gene, also known as Glutamate

May have a specific function in the mechanism or regulation of T-cell cytolytic activity.

SVTLE Protein, Calloselasma rhodostoma, Recombinant (His) is expressed in yeast with N-6xHis tag.

Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids.

Tripartite motif-containing Motif 5 is a protein that in humans is encoded by the TRIM5 gene.It is a 493 amino acids protein that belongs to the TRIM/RBCC

Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

SGMS2 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag.

Lipase CR 02 is a high-purity enzyme preparation, which is derived from the microbial fermentation of selected fungal strains. With a mechanism involving the hydrolysis of ester bonds in lipids, Lipase CR 02 facilitates the conversion of triglycerides into glycerol and free fatty acids. This catalytic activity positions it as an essential tool in various biochemical and industrial applications. In research settings, Lipase CR 02 is employed for studying lipid metabolism and its regulation. Industrially, it is leveraged in the food, detergent, and pharmaceutical sectors, particularly in the synthesis of enantiomerically pure compounds and the modification of fats and oils. Its high specificity and stability under a range of conditions make it a versatile choice for diverse processes, including biotransformations and the production of biodiesel.

VRK1 Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 45.6 kDa and the accession number is Q99986.

PR10A Protein, Coptis japonica, Recombinant (His & SUMO) is expressed in E. coli.

GGT1 Protein, Human, Recombinant (hFc) is expressed in HEK293 Cells. The accession number is P19440-1.

Cell surface receptor that binds to glycosaminoglycans, including chondroitin sulfate proteoglycans and heparan sulfate proteoglycans.

OTULIN Protein, Human, Recombinant (His) is expressed in E. coli with C-6xHis. The accession number is Q96BN8.

ALDH1A2 Protein, Mouse, Recombinant (His) is expressed in E. coli with N-6xHis. The accession number is Q62148.

HER3/ERBB3 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 69.3 kDa and the accession number is P21860-1.

Kallikrein 8 Protein, Mouse, Recombinant (E. coli, His) is expressed in E. coli.

Catalyzes the conversion of L-dopachrome into 5,6-dihydroxyindole-2-carboxylic acid (DHICA).

PTPRS Protein, Mus musculus, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag.

MMP-24 Protein, Mouse, Recombinant (His & Myc) is expressed in E. coli.

SIRT5 Protein, Mouse, Recombinant (E.