Ciclo celular/Ponto de verificação
Os inibidores do ciclo celular/ponto de verificação são compostos que interrompem a progressão normal do ciclo celular, particularmente em pontos de verificação regulatórios chave. Esses inibidores são cruciais para estudar a divisão celular, entender a proliferação de células cancerígenas e desenvolver terapias anticâncer. Ao direcionar fases específicas do ciclo celular, esses inibidores podem induzir a parada do ciclo celular, levando à apoptose ou senescência em células de divisão rápida. Na CymitQuimica, oferecemos uma ampla gama de inibidores de alta qualidade do ciclo celular/ponto de verificação para apoiar sua pesquisa em biologia do câncer, biologia celular e desenvolvimento de medicamentos.
Subcategorias de "Ciclo celular/Ponto de verificação"
- Aurora Quinase
- CDK
- Ciclo celular/Parada
- Chk
- c-Myc
- Dinamina
- DYRK
- Ferroptose
- HSP
- Integrinas
- Cinesina
- KSP
- LIM Quinase
- Microtúbulo associado
- PKC
- PLK
- Rho
- ROCK
- Wee1
Exibir 11 mais subcategorias
Produtos da "Ciclo celular/Ponto de verificação"
Ordenar por
DNA Gyrase-IN-16
CAS:DNA Gyrase-IN-16 (Compound 9) is an inhibitor of DNA gyrase, with an IC50 of 1.609 μM. It exhibits antibacterial properties, effectively inhibiting S. aureus and MRSA, with a MIC of 3.125 μM for both.Fórmula:C17H15N3O3Cor e Forma:SolidPeso molecular:309.319LSN2839567
CAS:LSN2839567 (Abemaciclib metabolite M2) is a CDK4 and CDK6 inhibitor with anticancer activity, inhibits CDK9, and can be used in breast cancer research.Fórmula:C25H28F2N8Pureza:99.14%Cor e Forma:SolidPeso molecular:478.54Palbociclib hydrochloride
CAS:Palbociclib hydrochloride is the salt form of Palbociclib, a selective and orally available CDK4 and CDK6 inhibitor for breast and hepatocellular carcinoma.Fórmula:C24H31Cl2N7O2Pureza:99.89%Cor e Forma:SolidPeso molecular:520.46BOS-172722
CAS:BOS-172722 is an inhibitor of monopolar spindle 1 (MPS1) checkpoint(IC50 of 2 nM).Fórmula:C24H30N8OPureza:99.37%Cor e Forma:SolidPeso molecular:446.556-Thio-2'-Deoxyguanosine
CAS:6-Thio-2'-Deoxyguanosine (β-TGdR) is a nucleoside analog and telomerase substrate.Fórmula:C10H13N5O3SPureza:97.52%Cor e Forma:SolidPeso molecular:283.31Calcium N5-methyltetrahydrofolate
CAS:Calcium N5-methyltetrahydrofolate (NSC-173328) is the calcium salt of levomefolic acid, which has been proposed for treatment of cardiovascular disease andFórmula:C20H23CaN7O6Pureza:98%Cor e Forma:SolidPeso molecular:497.51Folinic acid calcium
CAS:Folinic acid calcium (Leucovorin Calcium) is the active metabolite of folic acid. Leucovorin is used principally as an antidote to folic acid antagonists.Fórmula:C20H21CaN7O7Pureza:100% - 99.5%Cor e Forma:Yellow Crystalline PowderPeso molecular:511.51Opugotamig
Opugotamig is a chimeric antibody of the half-IG G1 -κ/(scFv -κ-heavy) -h-CH2-CH3 type, specifically targeting FOLR1.Cor e Forma:Odour LiquidML-099
CAS:ML-099 is a pan Ras-related GTPases activator that activates Rac1, Ras, GTP-binding protein (Rab7), Rab2A and cell division cycle 42.Fórmula:C14H13NO2SPureza:99.48%Cor e Forma:SolidPeso molecular:259.32Ref: TM-T22991
1mg48,00€2mg64,00€5mg96,00€10mg153,00€25mg305,00€50mg487,00€100mg710,00€1mL*10mM (DMSO)94,00€15(S)-HpETE
CAS:15(S)-HpETE is a product of arachidonic acid formed in the 15-lipoxygenase pathway and inhibits angiogenesis.Fórmula:C20H32O4Cor e Forma:SolidPeso molecular:336.47LNA-Adenosine
CAS:LNA-Adenosine (LNA-A) is a nucleoside analogue that acts as a ligand for adenosine A3 receptors.Fórmula:C11H13N5O4Pureza:98.62%Cor e Forma:SolidPeso molecular:279.25Famciclovir
CAS:Famciclovir (BRL 42810) inhibits Herpes virus DNA polymerase by mimicking nucleosides.Fórmula:C14H19N5O4Pureza:99.85%Cor e Forma:Off-White PowderPeso molecular:321.33SMN-C3
CAS:SMN-C3 (MV8T2MCK57) is an orally active modulator of SMN2 splicing, and has the potential to treat spinal muscular atrophy (SMA).Fórmula:C24H28N6OPureza:98.21% - 99.31%Cor e Forma:SolidPeso molecular:416.52Ilorasertib
CAS:Ilorasertib (ABT-348) inhibits Aurora kinases A/B/C & RET, PDGFRβ, Flt1 (IC50: 1-120 nM).Fórmula:C25H21FN6O2SPureza:96.17% - 98.03%Cor e Forma:SolidPeso molecular:488.54DNA Gyrase-IN-12
DNA Gyrase-IN-12 (Compound 6d) is an inhibitor of DNA gyrase. It exhibits antibacterial activity with MIC values ranging from 0.031 to 0.0625 μg/mL against Vancomycin-Intermediate Staphylococcus aureus (VISA) and Enterococcus faecium.Cor e Forma:Odour SolidKIF18A-IN-16
CAS:KIF18A-IN-16 (Compound 15) is a polycyclic KIF18A inhibitor. It is applicable in research related to tumors, including colon cancer, breast cancer, and lung cancer.Fórmula:C30H37N5O4SCor e Forma:SolidPeso molecular:563.71DHX9-IN-6
CAS:DHX9-IN-6 is a highly effective ATP-dependent RNA helicase A (DHX9) inhibitor, used in cancer research.Fórmula:C23H18ClFN4O4S2Pureza:99.71%Cor e Forma:SolidPeso molecular:533Dencatistat
CAS:Dencatistat is a highly selective and oral cytidine triphosphate synthase 1 CTPS1 inhibitor specific.CTPS1-IN-2 for B-cell, T-cell lymphomas and solid tumors.Fórmula:C24H27N7O5SPureza:98.85%Cor e Forma:SolidPeso molecular:525.584-Oxofenretinide
CAS:4-Oxofenretinide (3-Keto fenretinide) , a recently identified fenretinide metabolite, induces marked G2-M cell cycle arrest and apoptosis.Fórmula:C26H31NO3Pureza:96.89%Cor e Forma:SolidPeso molecular:405.53Ref: TM-T4189
1mg44,00€2mg55,00€5mg79,00€10mg113,00€25mg195,00€50mg293,00€100mg528,00€1mL*10mM (DMSO)96,00€Tacaciclib
CAS:Tacaciclib is a cyclin-dependent kinase (CDK) inhibitor with observed antineoplastic activity [1].Fórmula:C30H36N6O3Pureza:98%Cor e Forma:SolidPeso molecular:528.65
