Integrinas
Os inibidores de integrinas têm como alvo as integrinas, uma família de receptores de superfície celular que desempenham um papel crucial na adesão celular, migração e transdução de sinais. As integrinas estão envolvidas na regulação do ciclo celular, particularmente em processos como divisão e diferenciação celular. Inibir integrinas pode interromper esses processos, levando à parada do ciclo celular e apoptose, tornando esses inibidores valiosos na pesquisa do câncer e no estudo da metástase. Na CymitQuimica, oferecemos uma ampla gama de inibidores de integrinas de alta qualidade para apoiar sua pesquisa em regulação do ciclo celular, biologia do câncer e desenvolvimento terapêutico.
Produtos da "Integrinas"
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Gantofiban
CAS:Gantofiban is a glycoprotein IIb/IIIa (GP IIb/IIIa) antagonist used in the treatment of cardiovascular disease and may be used to study thrombosis.Fórmula:C21H29N5O6Pureza:99.21%Cor e Forma:SolidPeso molecular:447.48iRGD peptide
CAS:iRGD peptide: 9-amino acid cyclic compound (CRGDKGPDC), found through phage display in mice with tumors.Fórmula:C35H57N13O14S2Pureza:98.77%Cor e Forma:SolidPeso molecular:948.04STX-100
PY314 is a CHO-expressed humanized monoclonal antibody targeting TREM2 with antitumor activity for the study of metastatic renal cell carcinoma.Pureza:95% - 95%Cor e Forma:Odour LiquidC16Y
CAS:C16Y, a short peptide, serves as an inhibitor for the integrins αvβ3 and α5β1. It targets the cell membrane and exerts its antitumor activity by inhibiting angiogenesis.Fórmula:C78H115N17O17Cor e Forma:SolidPeso molecular:1562.85KOdiA-PC
CAS:KOdiA-PC is a truncated oxidized phospholipid and a CD36-targeting ligand found on oxLDL. It inhibits activation of TLR4 signaling components.Fórmula:C32H58NO11PCor e Forma:SolidPeso molecular:663.78Efalizumab
CAS:Efalizumab: humanized monoclonal antibody CD11a; modulates T cell activation/adhesion; for plaque psoriasis, psoriatic arthritis research.Pureza:SDS-PAGE:95% SEC-HPLC:98.77%Cor e Forma:LiquidPeso molecular:146.14 kDaObtustatin triacetate
Obtustatin triacetate, a 41-residue non-RGD disintegrin isolated from the venom of Vipera lebetina obtusa, serves as a potent and selective inhibitor of theFórmula:C184H284N52O57S8·3C2H4O2Pureza:99.51%Cor e Forma:SolidPeso molecular:4573.21ICAM-1-IN-1
CAS:ICAM-1-IN-1 is a potent and selective E-selectin(IC50 = 7 nM) and ICAM-1(IC50 = 5 nM) inhibitor.Fórmula:C15H11BrN2O2SPureza:99.34%Cor e Forma:SolidPeso molecular:363.23Ref: TM-T13147
1mg185,00€5mg393,00€10mg587,00€25mg935,00€50mg1.264,00€100mg1.700,00€500mg3.410,00€1mL*10mM (DMSO)432,00€Bimosiamose disodium
CAS:Bimosiamose disodium (TBC-1269Z), a pan-selectin inhibitor, has IC50s: E-selectin 88 μM, P-selectin 20 μM, L-selectin 86 μM; anti-inflammatory.Fórmula:C46H52Na2O16Pureza:98%Cor e Forma:SolidPeso molecular:906.88GSK 3008348 hydrochloride
CAS:GSK 3008348 hydrochloride is an αvβ6 integrin inhibitor used to confirm idiopathic pulmonary fibrosis.Fórmula:C29H37N5O2xHClPureza:99.54%Cor e Forma:SolidPeso molecular:0Tirofiban hydrochloride monohydrate
CAS:Tirofiban(MK383) hydrochloride monohydrate is a non-peptide glycoprotein IIb/IIIa antagonist. Cost-effective and quality-assured.Fórmula:C22H39ClN2O6SPureza:95.83% - 99.94%Cor e Forma:White SolidPeso molecular:495.07Natalizumab
CAS:Natalizumab used for the treatment of relapsing remitting multiple sclerosis and Crohn's disease.Pureza:98.00%Cor e Forma:LiquidPeso molecular:N/AH-Gly-Arg-Gly-Asp-Asn-Pro-OH
CAS:RGD peptide (GRGDNP) (RGD peptide GRGDNP(2TFA)) is a integrin-ligand interactions inhibitor.Fórmula:C23H38N10O10Pureza:100%Cor e Forma:SolidPeso molecular:614.61Cucurbitacin B
CAS:Cucurbitacin B (Cuc B) has profound in vitro and in vivo antiproliferative effects against human pancreatic Y cells.Fórmula:C32H46O8Pureza:97.10% - 99.33%Cor e Forma:SolidPeso molecular:558.7αvβ1 integrin-IN-2
CAS:αvβ1 integrin-IN-2 (compound 32) is a potent inhibitor of ανβ1 and α5β1 integrins, exhibiting IC50 values of 0.9 nM and 33 nM, respectively.Fórmula:C29H38N4O4Pureza:98%Cor e Forma:SolidPeso molecular:506.64A-205804
CAS:A-205804 is a specific and effective inhibitor of E-selectin( IC50=20 nM ) and ICAM-1(IC50=25 nM) expression.Fórmula:C15H12N2OS2Pureza:98.07% - 98.52%Cor e Forma:SolidPeso molecular:300.4Ref: TM-T2254
2mg44,00€5mg52,00€10mg81,00€25mg160,00€50mg271,00€100mg532,00€500mg1.169,00€1mL*10mM (DMSO)71,00€αvβ6 integrin inhibitor 2
CAS:αvβ6 Integrin Inhibitor 2 is a potent inhibitor of αvβ6 integrin, demonstrating an inhibition concentration (IC50) of 96.5 nM.Fórmula:C21H30N4O3Pureza:98%Cor e Forma:SolidPeso molecular:386.49OSU-T315
CAS:OSU-T315 (OSU-T315 (1,5-regioisomer)) (1,5-regioisomer) is a ILK inhibitor.Fórmula:C30H30F3N5OPureza:98.03%Cor e Forma:SolidPeso molecular:533.59Ref: TM-T5485
1mg97,00€2mg144,00€5mg235,00€10mg378,00€25mg647,00€50mg920,00€100mg1.225,00€500mg2.498,00€1mL*10mM (DMSO)306,00€RO0270608
CAS:RO0270608 is an α4β1/α4β7 integrin antagonist with anti-inflammatory activity for the study of allergic inflammatory responses.Fórmula:C24H19Cl3N2O4Pureza:98.55%Cor e Forma:SolidPeso molecular:505.78Cyclo(RGDyK) trifluoroacetate
CAS:Cyclo(RGDyK) trifluoroacetate is a potent and selective αVβ3 integrin inhibitor with IC50 of 20 nM.Fórmula:C31H43F6N9O12Pureza:≥95%Cor e Forma:SolidPeso molecular:847.72
