Nrf2
Nrf2 é um fator de transcrição que regula a expressão de proteínas antioxidantes e enzimas de desintoxicação, desempenhando um papel fundamental na defesa celular contra o estresse oxidativo e a inflamação. A ativação da sinalização Nrf2 oferece proteção contra várias doenças, incluindo câncer, neurodegeneração e distúrbios cardiovasculares. Os moduladores de Nrf2 estão sendo explorados por suas potenciais aplicações terapêuticas na redução de danos oxidativos e inflamação. Na CymitQuimica, oferecemos uma gama de moduladores da via Nrf2 de alta qualidade para apoiar sua pesquisa em estresse oxidativo, inflamação e prevenção de doenças.
Produtos da "Nrf2"
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NK-252
CAS:NK-252 is a potential activator of Nrf2. It has great Nrf2-activating potential.Fórmula:C13H11N5O3Pureza:98.32%Cor e Forma:SolidPeso molecular:285.26KI696
CAS:KI696 is a high-affinity probe that potently inhibits the interaction of Keap1 and NRF2.Fórmula:C28H30N4O6SPureza:98.42%Cor e Forma:SolidPeso molecular:550.63Ref: TM-T11758L
1mg144,00€5mg350,00€10mg558,00€25mg1.026,00€50mg1.406,00€100mg1.872,00€1mL*10mM (DMSO)449,00€Anti-NFE2L2 Antibody (9K94)
Anti-NFE2L2 Antibody (9K94) is a Mouse antibody targeting NFE2L2. Anti-NFE2L2 Antibody (9K94) can be used in ELISA, WB, IHC, IF, FCM.Pureza:>95%Cor e Forma:Odour LiquidML162
CAS:ML162 is a covalent glutathione peroxidase 4 (GPX4) inhibitor that induces ferroptosis. ML162 has antitumor activity. Cost-effective and quality-assured.Fórmula:C23H22Cl2N2O3SPureza:98.42% - 99.78%Cor e Forma:SolidPeso molecular:477.4NSC23925
CAS:NSC23925 is a selective and effective inhibitor of P-glycoprotein (Pgp).Fórmula:C22H26Cl2N2O2Pureza:98%Cor e Forma:SolidPeso molecular:421.36Rehmapicrogenin
CAS:Rehmapicrogenin regulates the Nrf2/ARE signaling pathway. Nrf2/ARE signaling pathway is the most important pathway of oxidative stress.Fórmula:C10H16O3Pureza:98%Cor e Forma:SolidPeso molecular:184.23Kinsenoside
CAS:Kinsenoside ((+)-Kinsenoside) shows significant antihepatotoxic, and anti-inflammatory activities.Fórmula:C10H16O8Pureza:100% - 99.92%Cor e Forma:SolidPeso molecular:264.23VVD-130037
CAS:VVD-130037 is a KEAP1 activator with potential antitumor activity.VVD-130037 inhibits tumor growth in advanced solid tumors by degrading NRF2.Fórmula:C17H17ClN4O2Pureza:99.01%Cor e Forma:SolidPeso molecular:344.8CDDO-EA
CAS:CDDO-EA (CDDO ethyl amide) is an activator of the Nrf2/antioxidant response element.Fórmula:C33H46N2O3Pureza:98.54%Cor e Forma:SolidPeso molecular:518.73Ref: TM-T10733
1mg85,00€5mg169,00€10mg298,00€25mg512,00€50mg732,00€100mg944,00€200mg1.264,00€1mL*10mM (DMSO)187,00€Ezetimibe
CAS:Ezetimibe (SCH 58235) is a Dietary Cholesterol Absorption Inhibitor. The physiologic effect of ezetimibe is by means of Decreased Cholesterol Absorption.Fórmula:C24H21F2NO3Pureza:97.28% - 99.97%Cor e Forma:SolidPeso molecular:409.43Ref: TM-T1593
1g283,00€10mg48,00€25mg62,00€50mg77,00€100mg87,00€200mg125,00€500mg197,00€1mL*10mM (DMSO)55,00€(E/Z)-BCI
CAS:(E/Z)-BCI (NSC-150117), a dual-specificity phosphatase 6 (DUSP6) inhibitor with anti-inflammatory properties, reduces LPS-induced inflammatory mediators and ROSFórmula:C22H23NOPureza:98.55%Cor e Forma:SolidPeso molecular:317.42Ref: TM-T11139
1mg80,00€5mg155,00€10mg283,00€25mg452,00€50mg638,00€100mg848,00€200mg1.121,00€1mL*10mM (DMSO)170,00€4-Octyl itaconate
CAS:4-Octyl Itaconate is a cell-permeable derivative of Itaconate, an anti-inflammatory metabolite.Fórmula:C13H22O4Pureza:99.3% - 99.94%Cor e Forma:SolidPeso molecular:242.31CPUY192018
CAS:CPUY192018 is an inhibitor of Keap1-Nrf2 protein-protein interactions, and can be used to study mitochondrial autophagy.Fórmula:C28H26N2O10S2Pureza:98.9%Cor e Forma:SolidPeso molecular:614.64TAT 14
CAS:TAT 14: a 14-mer peptide Nrf2 activator, anti-inflammatory, boosts Nrf2 protein, targets Keap1, no effect on mRNA.Fórmula:C137H230N48O39Pureza:98%Cor e Forma:SolidPeso molecular:3173.59ML334
CAS:ML334 (LH601A) is an NRF2 activator that inhibits cardiac fibroblast activation and proliferation ameliorating myocardial infarction-induced cardiac fibrosis.Fórmula:C26H26N2O5Pureza:98.06% - 98.06%Cor e Forma:SolidPeso molecular:446.49CBR-470-1
CAS:CBR-470-1 is a glycolytic phosphoglycerate kinase 1 inhibitor and Nrf2 activator that exhibits neuroprotective activity by activating the Keap1-Nrf2 cascade.Fórmula:C14H20ClNO4S2Pureza:98.03%Cor e Forma:SolidPeso molecular:365.9RA-839
CAS:RA-839 is a Keap1 conjugate and Nrf2 signaling activator, and an inhibitor of Keap1/Nrf2 interaction with anticancer activity.Fórmula:C25H28N2O4SPureza:98.38%Cor e Forma:SolidPeso molecular:452.57Gingerenone A
CAS:Gingerenone A, an Nrf2-Gpx4 activator isolated from ginger, has anticancer activity and inhibits iron death in mice with colitis secondary to liver injury (SLI)Fórmula:C21H24O5Pureza:98.94%Cor e Forma:SolidPeso molecular:356.41Nrf2 activator-1
CAS:Nrf2 activator-1 activates Nrf2; used for COPD, asthma, ALI, ARDS, pulmonary fibrosis research.Fórmula:C30H34N4O6SPureza:≥98%Cor e Forma:SolidPeso molecular:578.68KI696 isomer
CAS:KI696 isomer is an isomer of KI696, a low affinity probe for the study of immune and metabolic diseases.Fórmula:C28H30N4O6SPureza:99.8%Cor e Forma:SolidPeso molecular:550.63Ref: TM-T11758
1mg154,00€5mg464,00€10mg777,00€25mg1.568,00€50mg2.110,00€100mg2.783,00€1mL*10mM (DMSO)510,00€
