Canal TRP/TRPV
Os canais TRP (Potencial do Receptor Transitório), incluindo a subfamília TRPV, são um grupo de canais iônicos envolvidos em vários processos sensoriais, como sensação de temperatura, percepção da dor e osmorregulação. Os canais TRP são amplamente expressos em diferentes tecidos e desempenham um papel nas respostas fisiológicas aos estímulos ambientais. Os canais TRPV, em particular, estão envolvidos na detecção de mudanças de temperatura e estão implicados em condições como dor crônica, inflamação e câncer. Na CymitQuimica, oferecemos uma gama abrangente de moduladores de canais TRP/TRPV para apoiar sua pesquisa em biologia sensorial, manejo da dor e transdução de sinais.
Produtos da "Canal TRP/TRPV"
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MK-2295
CAS:MK-2295 is a potent TRPV1 antagonist. MK-2295 can be used in studies about the treatment of chronic pain.Fórmula:C27H31FN6O2Pureza:98.1% - 98.83%Cor e Forma:SolidPeso molecular:490.57SET 2
CAS:SET 2 is an antagonist of transient receptor potential vanilloid type 2(TRPV2) with an IC50 of 0.46 μM. SET 2 shows selectivity over TRPV1, TRPV3 and TRPV4.Fórmula:C17H21F3N4O2SPureza:98.43%Cor e Forma:SolidPeso molecular:402.43Ref: TM-T37097
5mg58,00€10mg96,00€25mg177,00€50mg300,00€100mg437,00€500mgA consultar1mL*10mM (DMSO)71,00€SB 452533
CAS:SB 452533 is an antagonist of the vanilloid receptor 1(pKb: 7.8).Fórmula:C18H22BrN3OPureza:98.52%Cor e Forma:SolidPeso molecular:376.29Ref: TM-T23322
2mg42,00€5mg64,00€10mg97,00€25mg183,00€50mg284,00€100mg411,00€200mg585,00€1mL*10mM (DMSO)85,00€Pyr6
CAS:Pyr6 (N-[4-[3,5-Bis(trifluoromethyl)-1H-pyrazol-1-yl]phenyl]-3-fluoro-4-pyridinecarboxamide) is a selective TRPC3 inhibitor with IC50 of 0.49 uM(Ca2+ influxFórmula:C17H9F7N4OPureza:98.89%Cor e Forma:SolidPeso molecular:418.27ICILIN
CAS:ICILIN (AG-3-5) is a synthetic TRPM8 ion channel super-agonist.Fórmula:C16H13N3O4Pureza:97.61% - ≥95%Cor e Forma:Light Yellow SolidPeso molecular:311.29ML-SI3
CAS:CCG-143140 is a GLP-1 receptor inverse agonists.Fórmula:C23H31N3O3SPureza:99.75%Cor e Forma:SolidPeso molecular:429.58Fingolimod hydrochloride
CAS:Fingolimod hydrochloride (FTY720) , a novel immune modulator, is a sphingosine 1-phosphate (S1P) antagonist (IC50: 0.033 nM in K562 and NK cells).Fórmula:C19H34ClNO2Pureza:99.26% - 99.83%Cor e Forma:White SolidPeso molecular:343.93CBP-1008
CBP-1008 is a dual-ligand peptide-drug conjugate (PDC) with MMAE, targeting folate receptor (FRα) and TRPV6. It exhibits high binding affinity to FRα and low affinity to TRPV6. CBP-1008 shows antitumor activity and can be utilized for research in advanced solid tumors such as colorectal cancer, breast cancer, non-small cell lung cancer, ovarian cancer, adrenocortical carcinoma, and follicular dendritic cell sarcoma.Cor e Forma:Odour SolidEvifacotrep
CAS:Evifacotrep: TRPC5 antagonist for neurological disease research (WO2020061162, compound 100).Fórmula:C18H12ClF4N5O2Pureza:98.6%Cor e Forma:SolidPeso molecular:441.77Ref: TM-T40042
1mg96,00€5mg188,00€10mg303,00€25mg465,00€50mg692,00€100mg1.026,00€200mg1.549,00€1mL*10mM (DMSO)160,00€AM-0902
CAS:AM-0902 is a potent and specific TRPA1 antagonist (IC50s: 71/131 nM for rTRPA1 and hTRPA1).Fórmula:C17H15ClN6O2Pureza:100%Cor e Forma:SolidPeso molecular:370.79SN 2
CAS:SN 2 is a novel and potent TRPML3 ion channel activator(EC50 = 1.13 μM). SN 2 also shares a similar antiviral effect against DENV2 and ZIKV.Fórmula:C17H21NOPureza:99.20%Cor e Forma:SolidPeso molecular:255.35Ref: TM-T12941
5mg52,00€10mg75,00€25mg149,00€50mg283,00€100mg415,00€200mg582,00€1mL*10mM (DMSO)52,00€Olvanil
CAS:Olvanil (N-Vannilyloleoylamide) is a vanilloid receptor agonist with EC50 of 0.7nM.Fórmula:C26H43NO3Pureza:95.06%Cor e Forma:SolidPeso molecular:417.62GSK1702934A
CAS:GSK1702934A is a TRPC3 agonist with pro-arrhythmic and positive inotropic effects and is used in the study of diabetes mellitus.Fórmula:C22H25N3O2SPureza:98.15%Cor e Forma:SolidPeso molecular:395.529-Phenanthrol
CAS:9-Phenanthrol is inhibitor of the transient receptor potential melastatin 4 (TRPM) channel, a Ca2+ -activated non-selective cation channel.Fórmula:C14H10OPureza:98.72%Cor e Forma:SolidPeso molecular:194.23Chembridge-5861528
CAS:Chembridge-5861528 (TCS 5861528) is a TRPA1 channel blocker that antagonizes AITC- and 4-HNE-evoked calcium influx with IC50 values of 14.3 and 18.7 μM.Fórmula:C19H23N5O3Pureza:99.97%Cor e Forma:SolidPeso molecular:369.42TRPV4 agonist-1
CAS:TRPV4 agonist-1 is an agonist of TRPV4 (EC50: 60 nM in the hTRPV4 Ca2+ assay).Fórmula:C25H23ClF2N4O2Pureza:98%Cor e Forma:SolidPeso molecular:484.93TRPV3 antagonist 74a
CAS:TRPV3 antagonist 74a (TRPV3 74a) is a specific TRPV3 antagonist for the study of neurological disorders.Fórmula:C17H17F3N2O2Pureza:≥98.0%Cor e Forma:SolidPeso molecular:338.32JC-229
CAS:JC-229 is a potent and selective TbRPA1 inhibitor that can inhibit RPA1 in Trypanosoma brucei. JC-229 can be used to study human African Trypanosomiasis (HAT).Fórmula:C20H14Cl4N2O3SPureza:97.14%Cor e Forma:SolidPeso molecular:504.21AMG2850
CAS:AMG2850 is a potent, orally bioavailable, and selective antagonist of transient receptor potential melastatin 8 (TRPM8).Fórmula:C19H17F6N3OPureza:99.05%Cor e Forma:SolidPeso molecular:417.35Ref: TM-T10300
1mg74,00€5mg170,00€10mg248,00€25mg445,00€50mg662,00€100mg848,00€1mL*10mM (DMSO)182,00€TC-I2000
CAS:TC-I2000 is an TRPM8 channel blocker. Inhibits icilin-induced TRPM8 channel activation in rTRPM8-expressing CHO cells with IC50 of 53 nM.Fórmula:C23H18F4N2OPureza:98.87%Cor e Forma:SolidPeso molecular:414.4ML204
CAS:ML204 is a novel potent antagonist that selectively modulates native TRPC4/C5 ion channels.Fórmula:C15H18N2Pureza:98.1% - 99.72%Cor e Forma:SolidPeso molecular:226.32Ref: TM-T2298
2mg35,00€5mg50,00€10mg74,00€25mg111,00€50mg145,00€100mg220,00€200mg284,00€500mg467,00€1mL*10mM (DMSO)52,00€ASP7663
CAS:ASP7663 is a TRPA1 Receptor Agonist and exhibiting an abdominal analgesic effect in vivo.Fórmula:C14H14FNO3Pureza:98.61%Cor e Forma:SolidPeso molecular:263.26GSK3395879
CAS:GSK3395879 is a selective and orally bioavailable antagonist of transient receptor potential vanilloid-4 (TRPV4) (IC50: 1 nM for hTRPV4).Fórmula:C20H15F4N3O5SPureza:98%Cor e Forma:SolidPeso molecular:485.41Mesendogen
CAS:Mesendogen is an inhibitor of transient receptor potential cation channel, subfamily M, member 6 (TRPM6) and 7 (TRPM7) and acts by inhibiting TRPM6/TRPM7Fórmula:C18H16ClF3N2OSPureza:98.90%Cor e Forma:SolidPeso molecular:400.85Apcin A HCL
CAS:Apcin A HCL is an Apcin derivative. Apcin A HCL is an anaphase-promoting complex (APC) inhibitor. Apcin-A HCL interacts strongly with Cdc20, and inhibits the ubiquitination of Cdc20 substrates. Apcin-A HCL can be used to synthesize the PROTAC CP5V [1].Fórmula:C10H15Cl4N5O2Pureza:99.30%Cor e Forma:SolidPeso molecular:379.07Ref: TM-T001
1mgA consultar2mg63,00€5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar200mgA consultar500mg2.792,00€Vanilloid receptor antagonist 1
CAS:Vanilloid receptor antagonist 1 (4-(7-Hydroxy-2-isopropyl-4-oxoquinazolin-3(4H)-yl)benzonitrile) is a potent vanilloid receptor TRPV1 antagonist.Fórmula:C18H15N3O2Pureza:98.14%Cor e Forma:SolidPeso molecular:305.33Ref: TM-T9247
1mg99,00€5mg235,00€10mg354,00€25mg602,00€50mg847,00€100mg1.206,00€1mL*10mM (DMSO)47,00€TRPA1-IN-2
CAS:TRPA1-IN-2 is a potent and orally active TRPA1 inhibitor with an IC50 value of 0.04 µM.TRPA1-IN-2 has anti-inflammatory activity.Fórmula:C24H25F3N4OPureza:98.05%Cor e Forma:SoildPeso molecular:442.48Ref: TM-T77511
1mg85,00€5mg187,00€10mg284,00€25mg482,00€50mg672,00€100mg905,00€200mg1.216,00€1mL*10mM (DMSO)207,00€FEMA-4809
CAS:FEMA-4809 activates TRPM8, the ion channel for cold sensation, and is used as a cooling agent.Fórmula:C17H17N3O2SPureza:99.19%Cor e Forma:SolidPeso molecular:327.4Ref: TM-T27308
1mg35,00€5mg78,00€10mg116,00€25mg190,00€50mg269,00€100mg383,00€200mg525,00€1mL*10mM (DMSO)88,00€TC-I 2014
CAS:TC-I 2014 shows antiallodynic properties in pain models.Fórmula:C23H19F6N3OPureza:98.75%Cor e Forma:SolidPeso molecular:467.41Ref: TM-T17006
1mg60,00€5mg127,00€10mg202,00€25mg406,00€50mg655,00€100mg1.074,00€200mg1.454,00€1mL*10mM (DMSO)133,00€AMG9810
CAS:AMG 9810 blocks capsaicin's action on TRPV1; human IC50=24.5 nM, rat IC50=85.6 nM.Fórmula:C21H23NO3Pureza:99.79% - 99.83%Cor e Forma:SolidPeso molecular:337.41JYL 1421
CAS:JYL 1421 (SC 0030) is an antagonist of TRPV1 receptor (IC50 = 8 nM).Fórmula:C20H26FN3O2S2Pureza:98.83%Cor e Forma:SolidPeso molecular:423.57Ref: TM-T15634
1mg70,00€5mg187,00€10mg305,00€25mg612,00€50mg938,00€100mg1.491,00€200mg1.985,00€1mL*10mM (DMSO)173,00€RN-1747
CAS:RN-1747: TRPV4 agonist (EC50: human 0.77 μM, mouse 4.0 μM, rat 4.1 μM), TRPM8 antagonist (IC50: 4 μM).Fórmula:C17H18ClN3O4SPureza:99.29%Cor e Forma:SolidPeso molecular:395.86Ref: TM-T16763
5mg44,00€10mg74,00€25mg126,00€50mg188,00€100mg316,00€200mg452,00€1mL*10mM (DMSO)47,00€HC067047 Hydrochloride(883031-03-6 free base)
CAS:HC-067047 hydrochloride, a TRPV4 antagonist, selectively inhibits human, rat, and mouse currents with IC50s: 486 nM, 133 nM, and 17 nM.Fórmula:C26H29ClF3N3O2Pureza:99.95%Cor e Forma:SolidPeso molecular:507.98Ref: TM-T4680L
1mg88,00€5mg172,00€10mg259,00€25mg425,00€50mg598,00€100mg810,00€200mg1.074,00€1mL*10mM (DMSO)217,00€RN9893
CAS:RN9893 is a selective and potent TRPV4 receptor antagonist with IC50 values of 320, 420 and 660 nM for TRPV4 receptors in mouse, human and rat, respectively.Fórmula:C21H23F3N4O5SPureza:99.89%Cor e Forma:SolidPeso molecular:500.49D-3263 hydrochloride
CAS:D-3263 hydrochloride (D3263 HCl salt) is enteric-coated, orally bioavailable transient receptor potential melatonin member 8 (TRPM8) agonist.Fórmula:C21H32ClN3O3Pureza:99.85%Cor e Forma:SolidPeso molecular:409.95PF-4840154
CAS:PF-4840154: potent TrpA1 agonist; EC50 of 97 nM (rat) & 23 nM (human); triggers nociception in mice.Fórmula:C26H38N6O2Pureza:98.48%Cor e Forma:SolidPeso molecular:466.62A 425619
CAS:A 425619 (1-(4-(TRIFLUOROMETHYL)BENZYL)-3-(ISOQUINOLIN-5-YL)UREA) is a potent TRPV1 antagonistFórmula:C18H14F3N3OPureza:99.35%Cor e Forma:SolidPeso molecular:345.32Ref: TM-T8562
1mg88,00€5mg170,00€10mg259,00€25mg425,00€50mg598,00€100mg810,00€200mg1.074,00€1mL*10mM (DMSO)177,00€HC-070
CAS:HC-070 is a TRPC5 and TRPC4 antagonist (IC50 = 9.3 nM and 46 nM).Fórmula:C22H20Cl2N4O4Pureza:97.06%Cor e Forma:SolidPeso molecular:475.32Ref: TM-T15465
1mg88,00€5mg170,00€10mg259,00€25mg429,00€50mg605,00€100mg815,00€200mg1.093,00€1mL*10mM (DMSO)168,00€A-967079
CAS:A 967079 is a potent, selective, and bioavailable inhibitor of the TRPA1 channel, with IC50 values of 67 and 289 nM for the human and rat isoforms, respectivelyFórmula:C12H14FNOPureza:98.34% - 99.75%Cor e Forma:SolidPeso molecular:207.24Ononetin
CAS:Ononetin (2',4'-Dihydroxy-2-(4-methoxyphenyl)acetophenone) is a TRPM3 channel blocker(IC50: 0.3 μM).Fórmula:C15H14O4Pureza:98.15%Cor e Forma:SolidPeso molecular:258.27GSK2193874
CAS:GSK2193874 was identified as a selective, orally active TRPV4 blocker.Fórmula:C37H38BrF3N4OPureza:98.79% - ≥95%Cor e Forma:SolidPeso molecular:691.62Ref: TM-T5640
1mg43,00€2mg57,00€5mg81,00€10mg127,00€25mg246,00€50mg404,00€100mg602,00€1mL*10mM (DMSO)111,00€AMTB hydrochloride
CAS:AMTB HCl: Novel TRPM8 blocker, relieves pain, treats urinary issues, moderates bladder reflexes in rats.Fórmula:C23H27ClN2O2SPureza:99.08%Cor e Forma:SolidPeso molecular:430.99Ref: TM-T19723
1mg37,00€5mg79,00€10mg126,00€25mg264,00€50mg449,00€100mg662,00€200mg939,00€1mL*10mM (DMSO)92,00€Pico145
CAS:Pico145 (HC-608) is a remarkable inhibitor of TRPC1/4/5 channels.Fórmula:C23H20ClF3N4O5Pureza:99.06%Cor e Forma:SolidPeso molecular:524.88Ref: TM-T16532
1mg77,00€5mg165,00€10mg240,00€25mg408,00€50mg562,00€100mg800,00€200mg1.074,00€1mL*10mM (DMSO)187,00€AMG 333
CAS:AMG 333 is TRPM8 antagonist with an IC50 of 13 nM,a Clinical Candidate for the Treatment of Migraine.Fórmula:C20H12F5N3O4Pureza:99.95%Cor e Forma:SolidPeso molecular:453.32SB-705498
CAS:SB705498 is a TRPV1 antagonist for hTRPV1. SB-705498 has been investigated for the treatment of Rhinitis, Chronic Cough, and Non-allergic Rhinitis.Fórmula:C17H16BrF3N4OPureza:99.16% - ≥95%Cor e Forma:SolidPeso molecular:429.23EIPA hydrochloride
CAS:EIPA hydrochloride also inhibits Na+/H+-exchanger (NHE) and macropinocytosisEIPA hydrochloride (L593754 hydrochloride) is a TRPP3 channel inhibitor with an IC50 of 10.5 μM.Fórmula:C11H19Cl2N7OPureza:98%Cor e Forma:SolidPeso molecular:336.22GFB-8438
CAS:GFB-8438 is a potent and subtype selective inhibitor of TRPC5(IC50s of 0.18 and 0.29 μM of hTRPC5 and hTRPC4, respectively).Fórmula:C16H14ClF3N4O2Pureza:99.58%Cor e Forma:SolidPeso molecular:386.76Ref: TM-T11394
2mg35,00€5mg52,00€10mg81,00€25mg117,00€50mg170,00€100mg250,00€200mg369,00€1mL*10mM (DMSO)58,00€AMG-0347
CAS:AMG-0347 inhibits TRPA1 ion channels in sensory neurons, blocking pain perception.Fórmula:C24H26F3N3O2Pureza:99.7%Cor e Forma:SolidPeso molecular:445.48Ref: TM-T29968
1mg226,00€5mg552,00€10mg735,00€25mg1.111,00€50mg1.491,00€100mg2.005,00€200mg2.707,00€1mL*10mM (DMSO)567,00€ML-SA1
CAS:ML-SA1 (Mucolipin synthetic agonist 1) is a selective TRPML agonist, inhibits DENV2 and ZIKV by promoting lysosomal acidification and protease activity.Fórmula:C22H22N2O3Pureza:99.71%Cor e Forma:SolidPeso molecular:362.42Ref: TM-T23004
2mg37,00€5mg51,00€10mg81,00€25mg150,00€50mg244,00€100mg364,00€200mg550,00€1mL*10mM (DMSO)58,00€JT010
CAS:JT010 is an effective agonist of TRPA1 (EC50 = 0.65 nM).Fórmula:C16H19ClN2O3SPureza:98.5%Cor e Forma:SolidPeso molecular:354.85M8-B Hydrochloride
CAS:M8-B Hydrochloride is a selective transient receptor potential melastatin-8 (TRPM8) channel antagonist.Fórmula:C22H25ClN2O3SPureza:99.33%Cor e Forma:SolidPeso molecular:432.96Ref: TM-T8442
2mg35,00€5mg52,00€10mg74,00€25mg145,00€50mg226,00€100mg335,00€200mg469,00€1mL*10mM (DMSO)64,00€ML329
CAS:ML329 is a small molecule inhibitor of MITF, inhibiting TRPM-1 promoter activity.Fórmula:C16H12N2O4SPureza:98.96%Cor e Forma:SolidPeso molecular:328.34Ref: TM-T4028
1mg52,00€2mg73,00€5mg115,00€10mg187,00€25mg424,00€50mg627,00€100mg893,00€1mL*10mM (DMSO)118,00€TRPM4-IN-1
CAS:TRPM4-IN-1 (4-chloro-2-(2-(2-chlorophenoxy)acetamido)benzoic acid) is a potent and selective inhibitor of TRPM4 with an IC50 of 1.5 μM.Fórmula:C15H11Cl2NO4Pureza:97.22%Cor e Forma:SolidPeso molecular:340.16TRPM8 antagonist 3
CAS:TRPM8 antagonist 3 is a blocker of TRPM8 (IC50 = 11 nM).Fórmula:C13H12N2O4SPureza:99.25%Cor e Forma:SolidPeso molecular:292.31Ref: TM-T9709
1mg62,00€5mg135,00€10mg202,00€25mg335,00€50mg490,00€100mg672,00€200mg905,00€1mL*10mM (DMSO)149,00€A-1165442
CAS:A-1165442 is a competitive TRPV1 antagonist. For human TRPV, the IC50 values is 9 nM.Fórmula:C22H20ClF2N3O2Cor e Forma:SolidPeso molecular:431.86ML204 hydrochloride
CAS:ML204 hydrochloride (ML204 HCl) is a TRPC4/TRPC5 channel antagonist.Fórmula:C15H19ClN2Cor e Forma:SolidPeso molecular:262.78HC-030031
CAS:HC-030031 (TOSLAB 829227) is a potent TRPA1 inhibitor, which antagonizes AITC- and formalin-evoked calcium influx with IC50s of 6.2 and 5.3 μM, respectively.Fórmula:C18H21N5O3Pureza:99.69% - ≥95%Cor e Forma:SolidPeso molecular:355.39Optovin
CAS:Optovin is a TRPA1 activator, which is reversibly photoactivated.Fórmula:C15H13N3OS2Pureza:100.00% - 99.16%Cor e Forma:SolidPeso molecular:315.41Ref: TM-T6617
1mg40,00€2mg51,00€5mg81,00€10mg97,00€25mg188,00€50mg314,00€100mg563,00€200mg687,00€1mL*10mM (DMSO)86,00€TRPM4-IN-2
CAS:NBA, or TRPM4-IN-2, is a potent TRPM4 inhibitor with IC50 of 0.16 μM, used in prostate and colorectal cancer research.Fórmula:C19H14ClNO4Pureza:99.21%Cor e Forma:SolidPeso molecular:355.77(S)-ABT 102
CAS:N-[(1S)-1H-inden-1-yl]-N'-indazol-4-ylurea is a strong TRPV1 blocker with a 123 nM IC50 against capsaicin.Fórmula:C21H24N4OPureza:99.41% - 99.78%Cor e Forma:SoildPeso molecular:348.44Ref: TM-T29522L
1mg77,00€5mg158,00€10mg225,00€25mg338,00€50mg472,00€100mg645,00€200mg868,00€1mL*10mM (DMSO)162,00€PF-05105679
CAS:PF-05105679 is a selective TRPM8 antagonist (IC50 = 103 nM). PF-05105679 can be used in research on cold-related pain.Fórmula:C26H21FN2O3Pureza:99.82%Cor e Forma:SolidPeso molecular:428.45Ref: TM-T16483
1mg48,00€2mg65,00€5mg96,00€10mg160,00€25mg305,00€50mg472,00€100mg710,00€200mg938,00€500mg1.444,00€1mL*10mM (DMSO)96,00€Pyr10
CAS:Pyr10, a pyrazole derivative, selectively inhibits TRPC3, not STIM1/Orai1, with IC50 of 0.72 μM in TRPC3-HEK293, and 13.08 μM in BRL-2H3 cells.Fórmula:C18H13F6N3O2SPureza:99.69% - 99.70%Cor e Forma:SolidPeso molecular:449.37IA-Alkyne
CAS:IA-Alkyne: TRPC agonist, cysteine-reactivity probe, potential in respiratory infection study.Fórmula:C8H12INOPureza:99.76%Cor e Forma:SolidPeso molecular:265.09Ref: TM-T15543
1mg59,00€5mg126,00€10mg187,00€25mg264,00€50mg329,00€100mg455,00€1mL*10mM (DMSO)120,00€TRPC6-PAM-C20
CAS:TRPC6-PAM-C20, a selective enhancer for TRPC6, boosts calcium in HEK cells and OAG-related platelet clumping, EC50: 2.37μM.Fórmula:C22H21NO4Pureza:98.16%Cor e Forma:SolidPeso molecular:363.41Pyr3
CAS:Pyr3 selectively blocks TRPC3 channels, reducing Ca2+ influx; it's effective at 700 nM.Fórmula:C16H11Cl3F3N3O3Pureza:99.47%Cor e Forma:SolidPeso molecular:456.63Ref: TM-T16687
1mg35,00€2mg52,00€5mg77,00€10mg97,00€25mg215,00€50mg363,00€100mg512,00€200mg738,00€500mg1.121,00€1mL*10mM (DMSO)86,00€RN-1734
CAS:RN-1734 is selective TRPV4 channel antagonist(IC50 of 2.3 μM,5.9 μM,3.2 μM for hTRPV4, mTRPV4 and rTRPV4,respectively)Fórmula:C14H22Cl2N2O2SPureza:99.1% - 99.30%Cor e Forma:SolidPeso molecular:353.31SB-366791
CAS:SB-366791 is a new and selective cinnamide TRPV1 antagonist.Fórmula:C16H14ClNO2Pureza:99.12%Cor e Forma:SolidPeso molecular:287.74TRPM8 antagonist 2
CAS:TRPM8 antagonist 2 is a potent and selective TRPM8 antagonist with an IC50 of 0.2 nM. TRPM8 antagonist 2 is used in the research of neuropathic pain syndromes.Fórmula:C26H26N2O2Pureza:98.10%Cor e Forma:SolidPeso molecular:398.5Ref: TM-T5698
1mg35,00€5mg70,00€10mg104,00€25mg170,00€50mg274,00€100mg439,00€200mg632,00€1mL*10mM (DMSO)78,00€NGD-8243
CAS:NGD-8243 (N-[4-(trifluoromethyl)phenyl]-7-[3-(trifluoromethyl)pyridin-2-yl]quinazolin-4-amine) is a TRPV1 inhibitor and can be used in studies for preventionFórmula:C21H12F6N4Pureza:95.26%Cor e Forma:SolidPeso molecular:434.34Vocacapsaicin hydrochloride
CAS:Vocacapsaicin hydrochloride (CA-008 hydrochloride) is a non-opioid TRPV1 agonist, a raw material for capsaicin, and is used for pain relief.Fórmula:C26H42ClN3O4Pureza:98.51% - 99.94%Cor e Forma:SolidPeso molecular:496.08HC-067047
CAS:HC-067047 is a potent and selective TRPV4 antagonist.Also inhibits the endogenous TRPV4-mediated response to 4α-PDH .Fórmula:C26H28F3N3O2Pureza:99.45% - 99.79%Cor e Forma:SolidPeso molecular:471.51SAR7334
CAS:SAR7334 (TRCP6-IN-1) is a potent and specific inhibitor of TRPC6(IC50 of 7.9 nM).Fórmula:C21H22ClN3OPureza:99.62% - 99.71%Cor e Forma:SolidPeso molecular:367.87Ref: TM-T12849
1mg71,00€5mg160,00€10mg250,00€25mg401,00€50mg567,00€100mg707,00€200mg938,00€1mL*10mM (DMSO)170,00€Asivatrep
CAS:Asivatrep (PAC14028) is a selective and potent antagonist of transient receptor potential vanilloid subtype 1 (TRPV1) for the study of atopic dermatitis.Fórmula:C21H22F5N3O3SPureza:95.13%Cor e Forma:SolidPeso molecular:491.48WS-12
CAS:WS-12 is a potent TRPM8 agonist that acts as a cooling agent (EC50 : 193 nM)Fórmula:C18H27NO2Pureza:99.99%Cor e Forma:Whitish To White Solid CrystallinePeso molecular:289.41ABT-239
CAS:ABT-239 is a novel, highly efficacious antagonist belonging to the non-imidazole class of histamine H3 receptor (H3R) antagonists.Fórmula:C22H22N2OPureza:100%Cor e Forma:SolidPeso molecular:330.42Ref: TM-T14087
1mg48,00€5mg96,00€10mg160,00€25mg313,00€50mg470,00€100mg660,00€200mg917,00€1mL*10mM (DMSO)96,00€JNJ-28583113
CAS:JNJ-28583113 is a TRPM2 antagonist, inducing phosphorylation of GSK3α and β subunits, protecting cells from oxidative stress-induced cell death.Fórmula:C19H21F3N2O2Pureza:98.57%Cor e Forma:SolidPeso molecular:366.38Ref: TM-T74779
1mg92,00€5mg215,00€10mg321,00€25mg494,00€50mg856,00€100mg1.478,00€200mg1.931,00€1mL*10mM (DMSO)225,00€PF-04745637
CAS:PF-04745637 is a potent and selective TRPA1 antagonist with an IC50 of 17 nM[1].Fórmula:C27H32ClF3N2O2Pureza:97.91% - 99.3%Cor e Forma:SolidPeso molecular:509Ref: TM-T64337
1mg73,00€5mg145,00€10mg197,00€25mg333,00€50mg475,00€100mg655,00€200mg882,00€1mL*10mM (DMSO)163,00€MSP3
CAS:MSP3 is an agonist of TRPV1 (EC50 = 0.87 μM) and shows antinociceptive and neuroprotective effects.Fórmula:C16H19NO3SPureza:99.46%Cor e Forma:SolidPeso molecular:305.39Ref: TM-T28118
2mg34,00€5mg52,00€10mg85,00€25mg170,00€50mg255,00€100mg378,00€200mg533,00€1mL*10mM (DMSO)74,00€M084
CAS:M084 (N-Butyl-1H-benzimidazol-2-amine) is a blocker of TRPC4/5 channel, with antidepressant and anxiolytic effects.Fórmula:C11H15N3Pureza:98.13%Cor e Forma:SolidPeso molecular:189.26Ref: TM-T8607
1mg88,00€5mg170,00€10mg259,00€25mg425,00€50mg598,00€100mg810,00€200mg1.074,00€1mL*10mM (DMSO)145,00€MDR-652
CAS:MDR-652 is a highly specific and efficacious agonist of nonpungent transient receptor potential vanilloid 1 (TRPV1) with Ki value of 11.4 nM and 23.8 nM forFórmula:C22H23ClFN3O2SPureza:99.96%Cor e Forma:SolidPeso molecular:447.95Ref: TM-T22360
1mg66,00€5mg144,00€10mg205,00€25mg369,00€50mg558,00€100mg800,00€200mg1.074,00€1mL*10mM (DMSO)157,00€BI-749327
CAS:BI-749327 is a high selectivity and orally bioavailable antagonist of TRPC6 (IC50s: 13 nM, 19 nM and 15 nM for mouse, human and guinea pig TRPC6).Fórmula:C23H21F3N4O2Pureza:99.68%Cor e Forma:SolidPeso molecular:442.43Ref: TM-T10537
1mg133,00€2mg177,00€5mg274,00€10mg432,00€25mg630,00€50mg825,00€100mg1.103,00€500mg2.205,00€1mL*10mM (DMSO)301,00€AM12
CAS:AM12 inhibits Lanthanide-evoked TRPC5 activity (IC50: 0.28 μM).Fórmula:C15H9BrO5Pureza:98%Cor e Forma:SolidPeso molecular:349.13BTD
CAS:BTD is a TRPC5 activator that activates heteromeric channel complexes composed of TRPC5 and its closest relatives TRPC1 or TRPC4.Fórmula:C24H33N3O4SCor e Forma:SolidPeso molecular:459.6TRPM4 inhibitor 8
CAS:TRPM4 inhibitor 8 is an inhibitor of Transient receptor potential melastatin 4(TRPM4) which contributes to viability, migration, cell cycle shift, and adhesion.Fórmula:C11H17BrN2Pureza:97%Cor e Forma:SolidPeso molecular:257.17Ref: TM-T9776
5mg47,00€10mg65,00€25mg96,00€50mg180,00€100mg283,00€200mg424,00€500mg697,00€1mL*10mM (DMSO)50,00€AC1903
CAS:AC1903 is a specific inhibitor of TRPC5 channel, and has been shown to suppress severe proteinuria and prevent podocyte loss.Fórmula:C19H17N3OPureza:98.45%Cor e Forma:SolidPeso molecular:303.36Linoleoyl Ethanolamide
CAS:Linoleoyl Ethanolamide is an endocannabinoid agent.Fórmula:C20H37NO2Pureza:99.97%Cor e Forma:SolidPeso molecular:323.51Ref: TM-T8425
1mg35,00€5mg67,00€10mg90,00€25mg164,00€50mg239,00€100mg348,00€200mg522,00€1mL*10mM (DMSO)85,00€BCTC
CAS:BCTC is a potent TRPV1 antagonist that inhibits capsaicin-induced and acid-induced activation of rat TRPV1 (IC50 of 35 and 6 nM, respectively)Fórmula:C20H25ClN4OPureza:99.21%Cor e Forma:SolidPeso molecular:372.89N4-benzyl-N2-methylquinazoline-2,4-diamine hydrochloride
CAS:N4-benzyl-N2-methylquinazoline-2,4-diamine hydrochloride is an inhibitor of TRPC4.Fórmula:C16H17ClN4Pureza:99.25%Cor e Forma:SolidPeso molecular:300.79Ref: TM-T8565
1mg88,00€5mg170,00€10mg259,00€25mg425,00€50mg598,00€100mg810,00€200mg1.074,00€1mL*10mM (DMSO)170,00€RQ-00203078
CAS:RQ-00203078 is a highly selective, potent and orally available TRPM8 antagonist.Fórmula:C21H13ClF6N2O5SPureza:98% - 99.17%Cor e Forma:SolidPeso molecular:554.85cim0216
CAS:CIM0216 is a synthetic TRPM3 activator whose potency and apparent affinity greatly exceeds that of the canonical TRPM3 agonist.Fórmula:C21H21N3O2Pureza:99.87%Cor e Forma:SolidPeso molecular:347.41Ref: TM-T9263
1mg47,00€2mg59,00€5mg92,00€10mg145,00€25mg298,00€50mg465,00€100mg702,00€500mg1.454,00€1mL*10mM (DMSO)92,00€AMG 517
CAS:AMG 517 is an effective and specific TRPV1 antagonist, antagonizes proton (IC50: 0.76 nM), capsaicin (IC50: 0.62 nM) and heat activation (IC50: 1.3 nM) of TRPV1Fórmula:C20H13F3N4O2SPureza:99.77% - 99.85%Cor e Forma:SolidPeso molecular:430.4GSK2798745
CAS:GSK2798745 is an orally active transient receptor potential vanilloid 4 (TRPV4) ion channel blocker (IC50s: 1.8 and 1.6 nM for hTRPV4 and rTRPV4).Fórmula:C25H28N6O3Cor e Forma:SolidPeso molecular:460.53MK6-83
CAS:MK6-83 is the transient receptor potential channel ML3 agonist.Fórmula:C16H20N2O2S2Pureza:99.71%Cor e Forma:SolidPeso molecular:336.47TRPV4 agonist-1 free base
CAS:TRPV4 agonist-1 free base (OUN67600) is an agonist of transient receptor potential vanilloid 4 (TRPV4;EC50 of 60 nM, in the hTRPV4 Ca2+ assay).Fórmula:C25H22F2N4O2Pureza:99.79%Cor e Forma:SolidPeso molecular:448.46ABT 102
CAS:ABT 102 (CHEMBL398338) is a selective antagonist of transient receptor potential vanilloid 1 (TRPV1) receptor.Fórmula:C21H24N4OPureza:98.38% - 99.72%Cor e Forma:SolidPeso molecular:348.44Ref: TM-T29522
1mg115,00€5mg249,00€10mg369,00€25mg562,00€50mg787,00€100mg1.054,00€200mg1.406,00€1mL*10mM (DMSO)259,00€(Z)-Capsaicin
CAS:(Z)-Capsaicin (Zucapsaicin) is a medication used to treat osteoarthritis of the knee and Others neuropathic pain.(Z)-Capsaicin is a synthetic cis isomer ofFórmula:C18H27NO3Pureza:97.33% - 99.67%Cor e Forma:SolidPeso molecular:305.41Resolvin D2
CAS:Resolvin D2 (RvD2) is a TRPV1 inhibitor and pro-ablative mediator with anti-inflammatory, anti-infective and pro-ablative effects.Fórmula:C22H32O5Pureza:98%Cor e Forma:SolidPeso molecular:376.49JNJ-17203212
CAS:JNJ-17203212 is a potent and selective antagonist of TRPV1 (human TRPV1 and rat TRPV1, IC50 of 65 nM and 102 nM).Fórmula:C17H15F6N5OPureza:99.18%Cor e Forma:SolidPeso molecular:419.32AP 18
CAS:AP-18 is a potent and selective TRPA1 inhibitor.Fórmula:C11H12ClNOPureza:99.85% - 99.87%Cor e Forma:SolidPeso molecular:209.67Ref: TM-T21543
2mg35,00€5mg50,00€10mg73,00€25mg140,00€50mg215,00€100mg338,00€500mg723,00€1mL*10mM (DMSO)50,00€TRPM8 antagonist WS-3
CAS:TRPM8 antagonist WS-3 (Cyclohexanecarboxamide) is an agonist of TRPM8( EC50 : 3.7 μM).Fórmula:C13H25NOPureza:97.64%Cor e Forma:DrypowderPeso molecular:211.34
