Receptor de Canabinóides
Os receptores de canabinoides são GPCRs que mediam os efeitos dos canabinoides endógenos (endocanabinoides) e dos fitocanabinoides, como aqueles encontrados na cannabis. Os dois principais tipos de receptores de canabinoides, CB1 e CB2, estão envolvidos na regulação de uma ampla gama de processos fisiológicos, incluindo percepção da dor, apetite, humor e função imunológica. Moduladores de receptores de canabinoides têm potencial terapêutico no tratamento de condições como dor crônica, epilepsia e esclerose múltipla. Na CymitQuimica, oferecemos uma ampla gama de moduladores de receptores de canabinoides de alta qualidade para apoiar sua pesquisa em neurofarmacologia, manejo da dor e imunologia.
Produtos da "Receptor de Canabinóides"
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OMDM-5
CAS:OMDM-5 is a potent vanilloid receptor type 1 (TRPV1, EC50 = 75 nM) agonist, showing weak ligand activity at cannabinoid type 1 receptor (CB1, Ki=4.9 μM).Fórmula:C26H44N2O3Pureza:99.72%Cor e Forma:SolidPeso molecular:432.64Ref: TM-T12306
1mg87,00€5mg187,00€10mg284,00€25mg452,00€50mg645,00€100mg867,00€200mg1.130,00€1mL*10mM (DMSO)221,00€A-836339
CAS:A-836339: Potent cannabinoid, CB2-focused (Ki=0.64nM), lesser CB1 affinity (Ki=270nM); analgesic, anti-inflammatory in mice.Fórmula:C16H26N2O2SPureza:99.94%Cor e Forma:SolidPeso molecular:310.45Ref: TM-T7375
2mg48,00€5mg92,00€10mg164,00€25mg266,00€50mg393,00€100mg557,00€200mg753,00€1mL*10mM (DMSO)94,00€CB2R agonist 3
CB2R agonist 3, a potent activator of cannabinoid receptor 2 (CB2R), exhibits an EC50 value of 0.37μM, indicative of its significant role in the immune system [Pureza:98%Cor e Forma:Odour SolidN-Arachidonyldopamine
CAS:N-Arachidonyldopamine (NADA) is a selective and potent endogenous CB1 receptor agonist (Ki: 250 nM).N-Arachidonyldopamine is also a potent and selective TRPV1Fórmula:C28H41NO3Pureza:97.65%Cor e Forma:SolidPeso molecular:439.63BML-190
CAS:BML-190 (Indomethacin morpholinylamide) 是一种 CB2 受体的配体,其对 CB2 受体 (Ki:435 nM) 和 CB1受体 (Ki> 2 μM)。Fórmula:C23H23ClN2O4Pureza:97.70%Cor e Forma:SolidPeso molecular:426.89CB1 antagonist 2
CAS:CB1 antagonist 2 (AM4113) is caimabinoid 1 (CB1) antagonist which inhibits CB1 in vivo with an IC50 of 25.5 nM.Fórmula:C17H12Cl3N3OPureza:99.75%Cor e Forma:SolidPeso molecular:380.66Δ8-THC-C8
CAS:Δ8-THC-C8 is a semi-synthetic cannabinoid. It acts as an agonist for the cannabinoid receptor 1 (CB1) with an EC50 value of 13.8 nM.Fórmula:C24H36O2Cor e Forma:SolidPeso molecular:356.54AM841
CAS:AM841, a high-affinity electrophilic ligand, covalently interacts with a cysteine residue in helix six, thus activating the CB1 cannabinoid receptor.Fórmula:C26H39NO3SPureza:98%Cor e Forma:SolidPeso molecular:445.66CB2 receptor agonist 9
CAS:CB2 receptor agonist 9 (Compound 33) is an orally active agonist of cannabinoid receptor 2 (CB2 receptor) with an EC50 of 16.2 nM. It inhibits the expression of TNF-α, IL-1β, and IL-6, demonstrating anti-inflammatory activity in a DSS-induced acute colitis model in mice.Fórmula:C16H23N3O2SCor e Forma:SolidPeso molecular:321.44CB2R/FAAH modulator-1
CAS:CB2R/FAAH modulator-1: agonizes CB2R, inhibits FAAH (IC50=4 μM), alters cytokine production; used in inflammation research. Ki: CB2R=14.8 nM, CB1R=241.3 nM.Fórmula:C24H27NO2Pureza:100%Cor e Forma:SoildPeso molecular:361.48Ref: TM-T67896
1mg77,00€5mg158,00€10mg225,00€25mg338,00€50mg472,00€100mg645,00€200mg868,00€1mL*10mM (DMSO)163,00€CB2 modulator 1
CAS:CB2 modulator 1 is a potent CB2 modulator. It can be used for the research for immune disorders, osteoporosis, inflammation, renal ischemia.Fórmula:C18H19F3N4O2Pureza:99.02%Cor e Forma:SolidPeso molecular:380.36Ref: TM-T10696
1mg35,00€5mg56,00€10mg79,00€25mg114,00€50mg167,00€100mgA consultar1mL*10mM (DMSO)64,00€Evofolin B
CAS:Evofolin B is a natural compound isolated from the stem bark of Zanthoxylum ailanthoides.Fórmula:C17H18O6Pureza:98%Cor e Forma:SolidPeso molecular:318.32JHU 75528
CAS:JHU 75528 (JHU-75528) is a novel PET tracer with inhibitory effects on CB that can be used to study the cannabinoid system in schizophrenic patients.Fórmula:C23H21Cl2N5O2Pureza:99.97%Cor e Forma:SolidPeso molecular:470.35CB2R/FAAH modulator-3
CAS:CB2R/FAAH modulator-3 (compound 27) is a modulator targeting at CB2R and FAAH.Fórmula:C22H31NO2Pureza:99.02%Cor e Forma:SoildPeso molecular:341.49Ref: TM-T67747
2mg38,00€5mg58,00€10mg90,00€25mg164,00€50mg259,00€100mg383,00€200mg545,00€1mL*10mM (DMSO)64,00€AM251
CAS:AM251: potent CB1 blocker (IC50: 8 nM), 306x CB2 selective; GPR55 activator (EC50: 39 nM).Fórmula:C22H21Cl2IN4OPureza:97.38% - 97.88%Cor e Forma:A Crystalline SolidPeso molecular:555.24Pregnenolone acetate
CAS:Pregnenolone acetate inhibits CB1 receptors, blocking THC effects and shielding the brain from cannabis intoxication.Fórmula:C23H34O3Pureza:99.66%Cor e Forma:White To Light Yellow Crystalline PowderPeso molecular:358.51Rimonabant
CAS:Rimonabant (SR141716) is an inverse agonist for the cannabinoid receptor CB1.Fórmula:C22H21Cl3N4OPureza:98% - 99.91%Cor e Forma:White Or Almost White Crystalline PowderPeso molecular:463.79GW 833972A
CAS:GW 833972A: selective CB2 agonist; reduces neural depolarization and citric acid cough in animals.Fórmula:C18H14Cl2F3N5OPureza:99.93%Cor e Forma:SoildPeso molecular:444.24ML-193
CAS:ML-193: GPR55 antagonist, IC50 221nM, 27x selective over GPR35/CB1/CB2, may aid Parkinson's symptoms.Fórmula:C28H25N5O4SPureza:97.74%Cor e Forma:SolidPeso molecular:527.59AM-2232
CAS:AM-2232 (UNII-40KCH8YIKP) is a potent and unselective agonist of the cannabinoid receptors.Fórmula:C24H20N2OPureza:99.37%Cor e Forma:SolidPeso molecular:352.43
