Açúcares e Nucleobases da Espinha Dorsal

Please enquire for more information about 3’,4-Dideoxyuridine including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 2’-Deoxy-2’-fluoro-N3-(butyn-3-yl)uridine including the price, delivery time and more detailed product information at the technical inquiry form on this page

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5,6-Diamino-1,3-dipropyluracil (DAU) is a synthetic drug that acts as an adenosine receptor antagonist. DAU binds to the adenosine receptors in the brain and inhibits the binding of adenosine, which may result in an anti-congestive effect. DAU has been found to be a potent inhibitor of the A2A adenosine receptor at nanomolar concentrations. This inhibition may be due to its ability to form covalent bonds with the receptor or its affinity for or blocking of agonist binding sites on the receptor. It also has been shown to have affinity for dopamine receptors, although it is not yet known if this activity contributes to its anti-congestive effects.

Please enquire for more information about 6-Chloro-2-iodopurine riboside including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 2-Aminopurine-9-beta-D-(3’,5’-di-O-benzoyl-2’-deoxy-2’-fluoro)arabinoriboside including the price, delivery time and more detailed product information at the technical inquiry form on this page

1-Cyclohexyluracil is a hydrogen bond donor. It has a chromophore and absorbs in the ultraviolet region of the electromagnetic spectrum. 1-Cyclohexyluracil is thermodynamically stable and has a constant, which is dependent on the pressure and temperature. The molecular weight of 1-Cyclohexyluracil is 174.16 g/mol and it has a molecular formula C5H6N4O2. 1-Cyclohexyluracil can bifurcate into two products, one with water as an intermediate, or it can undergo repair mechanism to regenerate itself. Intermolecular hydrogen bonding occurs between water molecules that are adjacent to each other on opposite sides of the molecule, which stabilizes the molecule by reducing energy fluctuations.

Cy5.5 is a near-infrared fluorescent dye (Ex=673 nm, Em=707 nm) that can be used to label biomolecules such as peptides, proteins, and oligonucleotides.Cost-effective and quality-assured.

Please enquire for more information about 2’-Deoxy-2’-fluoro-N3-allyluridine including the price, delivery time and more detailed product information at the technical inquiry form on this page

9-(2-Hydroxyethyl)adenine is a synthetic adenine derivative that has been used in the study of the structural and functional theory of DNA. It is a residue that is found in both RNA and DNA. Adenine forms hydrogen bonds with thymine, guanine, cytosine and uracil. 9-(2-Hydroxyethyl)adenine can be used to analyze environmental pollution by measuring the amount of free hydroxyl radicals present in a sample. It reacts spontaneously with other molecules at constant rates, but its reaction time depends on the number of complex molecules it interacts with. 9-(2-Hydroxyethyl)adenine has been shown to have anticancer effects on carcinoma cells by inhibiting ribonucleotide reductase activity.

N2-Pivaloylguanine is a versatile building block that can be used in the synthesis of many complex compounds. It has been shown to be an excellent reagent for the synthesis of heterocyclic molecules, and is also used as a reactant in a number of chemical reactions. N2-Pivaloylguanine is a high quality, useful intermediate that can be used to make other compounds, such as pharmaceuticals and agrochemicals. It is also a useful scaffold for the synthesis of research chemicals.

Please enquire for more information about 3’-Azido-3’-deoxy-5-methoxyuridine including the price, delivery time and more detailed product information at the technical inquiry form on this page

Cy7.5 (Cyanine 7.5) is an anthocyanin fluorescent dye that emits near infrared (NIR) fluorescence.

7-Deazaadenine is a pyrimidine compound that inhibits the enzyme kinase, which is involved in DNA synthesis. 7-Deazaadenine has significant cytotoxicity against cells and has been shown to inhibit the polymerase chain reaction (PCR). It can be used as an analytical tool for investigating enzymatic reactions by selectively inhibiting specific enzymes. 7-Deazaadenine binds to nitrogen atoms in DNA and inhibits the activity of proteases, which are enzymes that break down proteins. This drug also has pharmacokinetic properties such as oral absorption and distribution, metabolism, and elimination.

6-Azauracil is a heterocycle with the chemical formula C8H10N2O3. It is approved by the FDA to treat HIV infections and has been shown to have pharmacokinetic properties in humans. 6-Azauracil is structurally similar to uracil, which is found in RNA, but lacks the hydroxyl group on the para position of the heterocyclic ring. The synthesis of this drug was accomplished through acid complex formation with nucleotides and nitrous acid. The compound inhibits replication of retroviruses by competitive inhibition of primer binding. 6-Azauracil has also been shown to be toxic in rats, leading to congestive heart failure and death when administered at high doses. This drug may also act as an anti-inflammatory agent by inhibiting prostaglandin synthesis or platelet aggregation.

2'-(N-Methylanthraniloyl)guanosine 3',5'-cyclicmonophosphate sodium salt is a fluorescent analog of guanosine that has been synthesized to study the signal transduction pathway. It inhibits cyclic nucleotide phosphodiesterase, an enzyme that breaks down cyclic GMP, which is a second messenger involved in synaptic transmission. 2'-(N-Methylanthraniloyl)guanosine 3',5'-cyclicmonophosphate sodium salt has been shown to inhibit the enzymatic activity of cyclic nucleotide phosphodiesterase in vitro and in vivo. This compound also exhibits fluorescence properties and can be used for assays.

5(6)-ROX, a nucleic acid fluorescent label, serves as a reference dye in real-time polymerase chain reaction (PCR) applications.

3',3'-Difluoro-3'-Deoxythymidine is an anti-HIV drug that belongs to the group of nucleoside analogues. It is a synthetic nucleoside analogue that is structurally similar to thymidine. 3',3'-Difluoro-3'-Deoxythymidine has been shown to inhibit HIV replication in cell culture, and has shown a low incidence of resistance development. 3',3'-Difluoro-3'-Deoxythymidine inhibits HIV by competitively binding to viral reverse transcriptase, thereby blocking its activity and preventing the production of viral DNA. This drug also inhibits cellular RNA synthesis, which may be due to its inhibition of purine synthesis.

6-Mercaptopurine is an antigen binding molecule that is biocompatible with the human body. It binds to 6-mercaptopurine and inhibits the oxidation of proteins. The inhibition of protein oxidation has been shown to decrease disease activity in patients with inflammatory bowel disease. 6-Mercaptopurine also inhibits the production of inhibitor molecules, which are responsible for the development of cardiac effects such as arrhythmias and cardiomyopathy. 6-Mercaptopurine has inhibitory properties against polymerase chain reactions, which may be due to its ability to bind with protein thiols at high rates.

N4-Hydroxycytosine is an intramolecular hydrogen that inhibits the replication of viruses by inhibiting their DNA polymerase. It is a structural analogue of cytosine and can be found in both left- and right-handed forms, which are termed isomers. The chemical study of N4-hydroxycytosine has shown it to have inhibitory effects on human immunodeficiency virus and hepatitis C virus. 13C-NMR spectroscopy has been used to identify the chemical structure of N4-hydroxycytosine and its reactivity with other molecules. N4-Hydroxycytosine can be synthesized by the reaction between formaldehyde and 2,3,5,6-tetrafluorocytosine.

2-Thioxanthine is a hydrated form of xanthine, which is a purine base that occurs in all living cells. This compound has been shown to be able to inhibit the growth of resistant mutants and the formation of atherosclerotic lesions in mice. 2-Thioxanthine also inhibits the transfer reactions that are required for bacterial DNA synthesis. The stability of 2-thioxanthine can be increased by forming stable complexes with hydrochloric acid and by reducing the pH to less than 7. 2-Thioxanthine has been shown to have genotoxic effects on mouse liver cells and human fibroblasts, as well as pharmacological properties against cardiovascular disease.

8-Aminoguanine is an anti-cancer agent that is used to treat leukemia. It is a hydrophobic molecule with a redox potential of −0.20 V and has been shown to inhibit the enzyme ribonucleotide reductase in vitro and in vivo. 8-Aminoguanine inhibits the production of guanine nucleotides, which are necessary for DNA synthesis and cell division. This drug also has angiogenic properties, which may be due to its ability to stimulate the formation of new blood vessels by increasing nitric oxide synthase activity. 8-Aminoguanine has also been shown to improve congestive heart failure by reducing myocardial fibrosis and ventricular hypertrophy through activation of the glycosidic bond cleavage system.

5-Amino-6-azauracil is an isomeric amino acid derivative that inhibits the growth of gram-negative bacteria, such as Escherichia coli, Salmonella typhimurium and Klebsiella pneumonia. It has been shown to be effective against Shigella dysenteriae and coliforms. 5-Amino-6-azauracil inhibits the synthesis of adenosine by competitive inhibition with ATP. This compound also inhibits prophage induction in E. coli K12 and Shigella flexneri 2a.