Açúcares e Nucleobases da Espinha Dorsal

2-Chloroinosine 3',4',6'-triacetate is a reagent, useful intermediate, fine chemical, and speciality chemical. It is used as an important building block in organic synthesis. 2-Chloroinosine 3',4',6'-triacetate can be used as a versatile building block for the synthesis of many other compounds. The high quality and usefulness of this compound make it a good choice for research chemicals.

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DFHO is a Corn homologous ligand that fluoresces yellow upon excitation and is used to image RNA in living cells.

6-Fluoro-9-benzylpurine (6FBP) is a multidrug that inhibits the activity of pump proteins, which are responsible for pumping drugs out of cells. 6FBP binds to the drug-binding site on the protein. This binding prevents the drug from being pumped out of the cell and increases its concentration inside the cell. 6FBP has been shown to be effective against bacteria that have developed resistance through mutation in their efflux pump proteins. It also has a trifluoromethyl group, which facilitates its bonding to DNA and RNA molecules. 6FBP can be synthesized from other chemical compounds such as benzaldehyde or fluoroacetamide.

(E)-5-(2-Bromovinyl)uracil is a drug that has been shown to be effective against leukemic cells. It is a prodrug of 5-bromouracil, which is an antimetabolite and cytotoxic agent. (E)-5-(2-Bromovinyl)uracil has also been shown to be active against solid tumours, such as metastatic colorectal cancer, and bacteria. The mechanism of action involves the irreversible inhibition of the enzyme thymidylate synthase, which catalyzes the conversion of deoxyuridine monophosphate (dUMP) to thymidine monophosphate (dTMP). The drug binds to the dinucleotide phosphate pocket in the enzyme's active site and blocks access by dUMP. This leads to DNA synthesis errors, causing cell death. As a prodrug, it has low toxicity profiles and does not cause bone marrow suppression like

Cy5.5-SE is a cyanine dye, labeling amino-groups in oligonucleotides, peptides, and proteins.

5,6-Diaminouracil sulfate is an amine that is used as a precursor in the production of the anti-cancer drug 5-fluorouracil. It can be synthesized from diaminopyrimidine and uracil. This compound has two amino groups, which are both substituted with hydrogens. The aminouracile group is substituted with a hydrogen and an amino group. 5,6-Diaminouracil sulfate has pyrimidone rings that are fused together to form a six-membered ring.

Synthetic cytokinin; increases post-harvest life of vegetables

2,6-Dichloro-9-isopropylpurine is a hydrogenated purine derivative that belongs to the class of organometallic compounds. It is cytotoxic and causes significant cytotoxicity in colorectal carcinoma cells. The anticancer activity of 2,6-Dichloro-9-isopropylpurine may be due to its ability to inhibit DNA synthesis by cross-coupling with purines or by inhibiting the formation of hydrogen bonds between purines and their adjacent bases. This compound has been shown to be effective in treating wheat leaves infected with fungi, such as Rhizoctonia solani and Fusarium graminearum.

9-[2-(Diethylphosphonomethoxy)ethyl]adenine is a synthetic analog of adenine that is used as a pharmaceutical agent. It is an antiviral drug that prevents the synthesis of DNA and RNA in viruses, including papillomavirus, paramyxovirus, and filtration. 9-[2-(Diethylphosphonomethoxy)ethyl]adenine is also used to treat bromic conjugates and modifications. The chemical formula for this compound is C14H14N4O2P.