Açúcares e Nucleobases da Espinha Dorsal

N6-(2-Isopentenyl)adenine is a component of some nucleic acid molecules and can be synthesized from adenosine. It is used in vitro as a matrix effect to enhance the production of enzymes that are involved in the synthesis of amino acids, peptides, and proteins. N6-(2-Isopentenyl)adenine has been shown to stimulate the activity of enzymes such as urease, glucose oxidase, and horseradish peroxidase. This compound has been found to inhibit the replication of infectious agents by binding to DNA or RNA. The enzyme activities that are stimulated by this substance are important for the synthesis of essential biochemical compounds such as proteins and amino acids. In addition, it has been shown that N6-(2-Isopentenyl)adenine can inhibit autoimmune diseases and cytokinin.

6-Benzyladenine is a plant growth hormone that promotes the uptake and utilization of chlorophyll. It has been shown to stimulate the production of fatty acids in plants, which may be due to its ability to inhibit the activity of protease enzymes. 6-Benzyladenine also has an optimum concentration level at 2 μM, which leads to a significant increase in growth when applied to tissue cultures. In addition, this compound has been shown to inhibit the lipid peroxidation of membrane systems. 6-Benzyladenine is used as an analytical method for measuring protease activity in plants.

8-Mercaptopurine is a purine analog that inhibits viral replication in cells by binding to the ribofuranosyl moiety of the nucleic acid. It is used as an immunosuppressant drug and for the treatment of acute lymphocytic leukemia. 8-Mercaptopurine has been shown to inhibit viral replication by binding to the ribofuranosyl moiety of RNA, which prevents the formation of a DNA-RNA hybrid. This activity is inhibited by chlorine atoms and copper chloride. Structural studies have shown that 8-mercaptopurine forms glycosidic bonds with glucose, which may be responsible for its antiviral activity. The molecular modeling studies also revealed that 8-mercaptopurine interacts with methyltransferase, which may account for its inhibitory effects on DNA synthesis. 8-Mercaptopurine has also been found to be effective against a wide range of viruses including HIV, influenza, herpes simplex virus type 1

Intermediate in the synthesis of Decitabine

7-Deazaguanine is a nucleoside with potential as an antiviral agent. 7-Deazaguanine inhibits the activity of the enzyme RNA polymerase II, which is required for viral replication. The drug binds to the DNA template, inhibiting polymerase chain reaction (PCR), and prevents transcription of viral RNA by hydrogen bonding to its complementary strands. In addition, it has been shown to reduce the production of epidermal growth factor in cells.

2'-Trifluoromethane sulfonate-2,3'-anhydro-1-(beta-D-xylofuranosyl)uracil is a nucleophile that hydrolyzes to form uracil. It can also be used as a linker in the formation of hexamethylphosphoric chloride and triamide derivatives.

CY7 (Sulfo-Cyanine7) is a fluorescence labeling agent (Ex=750 nm, Em=773 nm). Cy7 is used for labeling oligonucleotides, antibodies, peptides, and proteins.