Açúcares e Nucleobases da Espinha Dorsal

Please enquire for more information about 1,3-Di(benzyloxymethyl)-5-fluorouracil including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 3’-Deoxy-3’-fluoro-4-deoxyuridine including the price, delivery time and more detailed product information at the technical inquiry form on this page

5-Vinyluracil (5-U) is a trifluoroacetic acid derivative of uracil that inhibits the growth of Streptococcus faecalis by blocking the synthesis of DNA. 5-U has been shown to inhibit the growth of cancer cells in cell culture. 5-U prevents the formation of hydrogen bonds, which are essential for DNA replication. It also inhibits glycosidic bond formation and intramolecular hydrogen bonding.

1,3-Dimethyluracil is a uracil derivative that is used as a hydrogen-bond donor, which helps to repair DNA. It has been shown to have a kinetic isotope effect in the deuterium isotope effect studies. The carbonyl group of 1,3-dimethyluracil can form hydrogen bonds with the guanine base in DNA and lead to the formation of an adduct. This adduct can be repaired by nucleotide excision repair when it forms a dimer with another 1,3-dimethyluracol molecule or by base excision repair when it forms a dimer with another purine or pyrimidine base. Aqueous solutions of 1,3-dimethyluracil are stable for short periods of time but decompose rapidly on heating. X-ray crystal structures show that 1,3-dimethyluracil binds to hydrochloric acid and x-ray crystallographic analysis

Please enquire for more information about 2',3',4-Triacetyl-6-azauridine including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 2-Dimethylamino-6-hydroxypurine including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 9-(3-Deoxy-3-fluoro-beta-D-ribofuranosyl)-2-chloro-6-(naphthalen-1-yl)purine including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 5,6-Diamino-4-thiouracil including the price, delivery time and more detailed product information at the technical inquiry form on this page

6-Chloro-9-(tetrahydro-2H-pyran-2-yl)purine is a nucleoside analog that is used to treat various types of cancer. It is a c-h bond regiospecific nucleophile that forms the 6-chloro 9-(tetrahydro-2H-pyran-2-yl)purine intermediate. The chloride ion acts as a nucleophile in the first step of this process, which results in the formation of an organocuprate and glyoxylate. 6CPP binds to DNA and inhibits RNA synthesis, leading to cell death by apoptosis or necrosis. This drug has been shown to be effective for treating human cell lines. 6CPP is also known for its antitumor effects, which may be due to its ability to inhibit phosphonates and cross-coupling reactions.