Moduladores GABA
Os moduladores de GABA são compostos que influenciam a função dos receptores de GABA (ácido gama-aminobutírico), os principais receptores inibitórios de neurotransmissores no sistema nervoso central. Estes moduladores podem aumentar ou inibir a atividade GABAérgica, afetando a excitabilidade neuronal e a transmissão sináptica. Os moduladores de GABA são cruciais no tratamento e estudo de vários distúrbios neurológicos e psiquiátricos, incluindo ansiedade, epilepsia e insônia. Na CymitQuimica, oferecemos uma ampla gama de moduladores de GABA para apoiar sua pesquisa em neurociência, farmacologia e neuroterapêutica.
Produtos da "Moduladores GABA"
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Methylbarbital
CAS:Produto ControladoApplications Methylbarbital is a barbituate which displays anticonvulsant/antiepileptic activity. References Lien, E. et al.: J. Pharm. Sci.., 68, 463 (1979); Kesselheim, A. et al.: Drugs, 70, 605 (2010);Fórmula:C9H14N2O3Cor e Forma:WhitePeso molecular:198.221-Methyl-5-phenyl-1,3-dihydro-2H-benzo[e][1,4]diazepin-2-one
CAS:Pureza:98%Peso molecular:250.30099487304688Pentobarbital
CAS:Produto ControladoApplications Pentobarbital is a narcotic and sedative barbiturate drug formerly used to relieve insomnia. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Schafer, E.W., et al.: Toxicol. Appl. Pharmacol., 21, 315 (1972), Woster, P.S., et al.: Clin. Pharm., 9, 762 (1990), Evans, A.T., et al.: J. Am. Vet. Med. Assoc., 203, 664 (1993),Fórmula:C11H18N2O3Cor e Forma:NeatPeso molecular:226.27Allobarbital-d10
CAS:Produto ControladoApplications Labelled Allobarbital, a barbiturate derivative that is primarily used as an anticonvulsant. Allobarbital also shows hypnotic activity and is used to boost the activity of analgesic drugs. Studies show that Allobarbital is an effective promoters of hepatocarcinogenesis. Allobarbital is a Controlled Substance. References Tateoka, Y. et al.: Yakug. Zas., 106, 504 (1986); Crawford, J.M. et al.: Neuropharmacology, 9, 31 (1970); Rice, J.M. et al.: Carcinogenesis, 15, 395 (1994);Fórmula:C10D10H2N2O3Cor e Forma:White To Off-WhitePeso molecular:218.275Clozapine N-Oxide
CAS:Produto ControladoImpurity CLOZAPINE N-OXIDE IMPURITY Applications Clozapine N-Oxide is a 5-HT2 antagonist. It is a major metabolite of clozapine (C587500) that can be monitored by HPLC. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Baldessarini, E., et al.: Neuropsychopharmacol., 9, 117 (1993); Lin, G., et al.: J. Pharm. Sci, 83, 1412 (1994); Roth, B.L., et al.: J. Pharmacol. Exp. Ther., 268, 1403 (1994)Fórmula:C18H19ClN4OCor e Forma:Light Yellow To YellowPeso molecular:342.82Valproic Acid EP Impurity E
CAS:Produto ControladoFórmula:C5H11NOCor e Forma:NeatPeso molecular:101.15Clorazepic Acid Ethyl Ester
CAS:Produto ControladoApplications Clorazepic Acid Ethyl Ester is an ethyl ester of Clorazepic Acid (C587365, Dipotassium Salt) which is an anxiolytic. References Cone, E., et al.: J. Pharm. Sci., 73, 243 (1984), Maurer, H., et al.: J. Anal. Toxicol., 25, 237 (2001), Beyer, J., et al.: Ther. Drug Monit., 27, 151 (2005)Fórmula:C18H15ClN2O3Cor e Forma:White To Light YellowPeso molecular:342.78
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