FAK
FAK (focal adhesion kinase) inhibitors target FAK, a kinase involved in cell adhesion, migration, and angiogenesis. FAK is frequently overexpressed in tumors and contributes to the formation of new blood vessels that supply nutrients to the tumor. Inhibiting FAK can disrupt these processes, making FAK inhibitors valuable tools in cancer therapy and angiogenesis research. At CymitQuimica, we provide a comprehensive range of high-quality FAK inhibitors to support your research in cell biology, cancer, and angiogenesis.
Products of "FAK"
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Corosolic acid
CAS:Corosolic acid inhibits angiogenesis, suppresses FAK, fights various cancers, induces apoptosis, and degrades β-catenin.Formula:C30H48O4Purity:99.46% - 99.88%Color and Shape:Fine-Brown Yellow PowderMolecular weight:472.7FAK-IN-21
CAS:FAK-IN-21 (compound 9) is a FAK inhibitor with an IC50 value of 37.52 nM. It inhibits cell growth and the phosphorylation of FAK, making it useful for research into diffuse gastric cancer.Formula:C22H22F2N8O3SColor and Shape:SolidMolecular weight:516.52FAK-IN-12
FAK-IN-12 (Compound 12S) is a selective FAK inhibitor with an IC50 of 47 nM.Purity:98%Color and Shape:Odour SolidRoslin 2 bromide
CAS:Roslin 2 bromide (Benzylhexamethylenetetramine bromide) is a p53 reactivator that disrupts the binding of FAK and p5.Formula:C13H19BrN4Purity:97.07%Color and Shape:SolidMolecular weight:311.22Defactinib hydrochloride
CAS:Defactinib hydrochloride (PF 04554878 hydrochloride) is a novel inhibitor of FAK.Formula:C20H22ClF3N8O3SPurity:98.06% - 98.78%Color and Shape:SolidMolecular weight:546.95Ifebemtinib
CAS:Ifebemtinib (BI-853520) is an adhesion plaque kinase inhibitor with anti-tumour activity for the study of breast cancer.Formula:C28H28F4N6O4Purity:98.07% - 99.82%Color and Shape:SolidMolecular weight:588.55NAMI-A
CAS:NAMI-A is a ruthenium-based compound with selective activity against tumor metastasis.NAMI-A inhibits cancer cell adhesion and migration.Formula:C8H15Cl4N4ORuSPurity:98%Color and Shape:SolidMolecular weight:458.18AMP-945
CAS:AMP-945 is a proprietary focal adhesion kinase (FAK) inhibitor.Formula:C28H32F3N5O2Purity:99.60%Color and Shape:SolidMolecular weight:527.58Ref: TM-T9576
1mg97.00€5mg188.00€10mg311.00€25mg533.00€50mg755.00€100mg1,035.00€1mL*10mM (DMSO)254.00€Adhesamine diTFA
CAS:Adhesamine diTFA, a dumbbell-shaped molecule, activates the MAPK/FAK pathway. It promotes adhesion and growth in mammalian cells and accelerates differentiation and enhances the survival rate of primary cultured mouse hippocampal neurons.Formula:C28H32Cl2F6N8O6S2Color and Shape:SolidMolecular weight:825.63FAK-IN-7
CAS:FAK-IN-7 has potential antiproliferative activity and is a FAK inhibitor.Formula:C16H13N3OSPurity:98.2%Color and Shape:SolidMolecular weight:295.36GSK2256098
CAS:GSK2256098 (GTPL7939) is a small molecule FAK kinase inhibitor.Formula:C20H23ClN6O2Purity:99.46% - 99.52%Color and Shape:SolidMolecular weight:414.89Ref: TM-T2281
1mg47.00€2mg60.00€5mg88.00€10mg137.00€25mg263.00€50mg449.00€100mg660.00€500mg1,388.00€1mL*10mM (DMSO)88.00€MY-1576
MY-1576 is a FAK inhibitor with an IC50 of 8 nM. It activates the Hippo pathway, thereby inhibiting YAP/TAZ regulation. Additionally, MY-1576 effectively suppresses tumor growth in the KYSE30 xenograft mouse model, demonstrates good safety, and efficiently downregulates FAK autophosphorylation and YAP/TAZ levels in vivo.Formula:C25H29ClN8O2Color and Shape:SolidMolecular weight:509PF-03814735
CAS:PF-03814735 is a novel, potent and reversible inhibitor of Aurora A/B with IC50of 0.8 nM/5 nM, is less potent to Flt3, FAK, TrkA, and minimally active to Met and FGFR1. Phase 1.Formula:C23H25F3N6O2Purity:98%Color and Shape:SolidMolecular weight:474.48PND-1186
CAS:PND-1186 (VS-4718) is a reversible and specific FAK inhibitor (IC50: 1.5 nM).Formula:C25H26F3N5O3Purity:99.14% - 99.75%Color and Shape:SolidMolecular weight:501.5PF-573228
CAS:PF-573228 is an ATP-competitive FAK inhibitor. In a cell-free assay, the IC50 of FAK is 4 nM.Formula:C22H20F3N5O3SPurity:96.58% - 98.86%Color and Shape:SolidMolecular weight:491.49Anti-PTK2 Antibody (4T687)
Anti-PTK2 Antibody (4T687) is an antibody targeting PTK2. Anti-PTK2 Antibody (4T687) can be used in ELISA, IHC.Color and Shape:Odour LiquidNVP-TAE 226
CAS:NVP-TAE 226: Potent FAK inhibitor, IC50=5.5nM, stronger vs Pyk2, IC50=3.5nM, weaker against IGF-1R, InsR, c-Met, ALK.Formula:C23H25ClN6O3Purity:98.07% - 98.78%Color and Shape:SolidMolecular weight:468.94Ref: TM-T1918
1mg48.00€2mg63.00€5mg101.00€10mg163.00€25mg264.00€50mg378.00€100mg567.00€1mL*10mM (DMSO)101.00€FAK-IN-14
CAS:FAK-IN-14 is a FAK inhibitor that induces apoptosis and cell cycle arrest. FAK-IN-14 has a more significant inhibitory effect on FAK, FGFR1 and Pyk2.Formula:C21H24BrN7OSPurity:99.7%Color and Shape:SoildMolecular weight:502.43PF-562271
CAS:PF-562271 is an effective ATP-competitive, reversible inhibitor of FAK(IC50=1.5 nM) and Pyk2 kinase(IC50=13 nM).Formula:C21H20F3N7O3SPurity:100% - 97.65%Color and Shape:SolidMolecular weight:507.49Ref: TM-T2465
1mg59.00€5mg127.00€10mg159.00€25mg240.00€50mg378.00€100mg567.00€200mg793.00€1mL*10mM (DMSO)140.00€Batatasin III
CAS:Batatasin III inhibits cancer migration and invasion by suppressing epithelial to mesenchymal transition and FAK-AKT signals and possesses anti-cancerFormula:C15H16O3Purity:99.16%Color and Shape:SolidMolecular weight:244.29
