FAK
FAK (focal adhesion kinase) inhibitors target FAK, a kinase involved in cell adhesion, migration, and angiogenesis. FAK is frequently overexpressed in tumors and contributes to the formation of new blood vessels that supply nutrients to the tumor. Inhibiting FAK can disrupt these processes, making FAK inhibitors valuable tools in cancer therapy and angiogenesis research. At CymitQuimica, we provide a comprehensive range of high-quality FAK inhibitors to support your research in cell biology, cancer, and angiogenesis.
Products of "FAK"
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FAK-IN-15
FAK-IN-15 is a highly potent focal adhesion kinase (FAK) inhibitor with antitumor activity.Formula:C21H24ClN7OSPurity:99.08%Color and Shape:SolidMolecular weight:457.98Chloropyramine hydrochloride
CAS:Chloropyramine hydrochloride (Alergosan) is a histamine receptor H1 antagonist.Formula:C16H20ClN3·HClPurity:99.45% - 99.8%Color and Shape:SolidMolecular weight:326.26Defactinib analogue-1
CAS:Defactinib analogue-1 (Compound 7) serves as a ligand for the target protein FAK, and is utilized in the synthesis of PROTAC FAK degrader 1.Formula:C20H20F3N5O3SColor and Shape:SolidMolecular weight:467.47Conteltinib
CAS:Conteltinib (CT-707) is an enzyme inhibitor with antitumor activity targeting FAK, ALK and Pyk2. It can be used to study lymphoma.Formula:C32H45N9O3SPurity:98.12% - 99.54%Color and Shape:SolidMolecular weight:635.82Ref: TM-T14997
1mg77.00€5mg167.00€10mg240.00€25mg409.00€50mg572.00€100mg800.00€1mL*10mM (DMSO)227.00€PF-431396
CAS:PF-431396 is a dual PYK2/FAK inhibitor (IC50: 11/2 nM).Formula:C22H21F3N6O3SPurity:98.83% - 99.82%Color and Shape:SolidMolecular weight:506.5Nitidine chloride
CAS:1.Formula:C21H18ClNO4Purity:96.59% - 98.91%Color and Shape:SolidMolecular weight:383.82ALK inhibitor 1
CAS:ALK inhibitor 1 is a selective ALK kinase inhibitor.Formula:C23H28BrN7O3SPurity:98.27%Color and Shape:SolidMolecular weight:562.48Ref: TM-T10285
1mg52.00€5mg116.00€10mg170.00€25mg340.00€50mg472.00€100mg645.00€1mL*10mM (DMSO)143.00€FAK-IN-11
FAK-IN-11 (Compound 4l), a FAK inhibitor, specifically targets the ATP binding pocket of FAK to prevent its phosphorylation.Formula:C25H41NO3Purity:98%Color and Shape:SolidMolecular weight:403.6Ifebemtinib hydrochloride
Ifebemtinib (BI-853520) hydrochloride is a potent FAK (focal adhesion kinase) inhibitor with oral bioavailability, exhibiting an IC50 of 1 nM for recombinant FAK. Ifebemtinib hydrochloride demonstrates antiproliferative activity against cancer cells.Formula:C28H29ClF4N6O4Color and Shape:SolidMolecular weight:625.01GSK215
CAS:GSK215: potent, selective PROTAC degrader of FAK (pDC50=8.4), combines FAK inhibitor VS-4718 and VHL E3 ligase binder, causes fast, lasting FAK degradation.Formula:C50H59F3N10O6SPurity:99.3%Color and Shape:SoildMolecular weight:985.13PF-562271 hydrochloride
CAS:PF-562271 hydrochloride (PF-562271 HCl) is a potent, ATP-competitive, reversible inhibitor of FAK with IC50 of 1.5 nM, ~10-fold less potent for Pyk2 than FAK.Formula:C21H20F3N7O3SHClPurity:98.52%Color and Shape:SolidMolecular weight:543.95Defactinib
CAS:Defactinib (VS-6063) is a second-generation inhibitor of FAK. Defactinib has potential antitumor activity. Cost-effective and quality-assured.Formula:C20H21F3N8O3SPurity:98% - 99.8%Color and Shape:SolidMolecular weight:510.49ALK-IN-29
ALK-IN-29 (compound 4c) exhibits inhibitory effects on tyrosine protein kinases such as ALK, CDK2/CyclinE1, and FAK, with the strongest inhibition observed against ALK kinase, displaying a 40.63% inhibition rate at a concentration of 10 μM. ALK-IN-29 is applicable in cancer research.Formula:C29H32FN3OColor and Shape:SolidMolecular weight:457.58Y15
CAS:Y15 (1,2,4,5-Benzenetetramine tetrahydrochlor) is a potent and specificsmall-molecule FAK scaffolding inhibitor that inhibits its autophosphorylation activity,Formula:C6H14Cl4N4Purity:98% - 98%Color and Shape:Dark Brown CrystalsMolecular weight:284.01Ref: TM-T7119
10mg50.00€25mg69.00€50mg82.00€100mg137.00€200mg188.00€500mg331.00€1mL*10mM (DMSO)48.00€FAK activator 1
CAS:ZINC40099027 is a FAK activator that induces gastric mucosal repair in persistent aspirin-associated gastric injury.Formula:C23H26F3N3O3Purity:98.85%Color and Shape:SoildMolecular weight:449.47Ref: TM-T77665
1mg99.00€5mg229.00€10mg383.00€25mg627.00€50mg1,005.00€100mg1,589.00€200mg2,078.00€1mL*10mM (DMSO)296.00€Masitinib
CAS:Masitinib (AB1010) is a tyrosine-kinase inhibitor used in the treatment of mast cell tumors in animals, specifically dogs.Formula:C28H30N6OSPurity:100% - 99.55%Color and Shape:SolidMolecular weight:498.642119738-71-3
CAS:Compound 2119738-71-3 interacts with the FAK receptor.Formula:C25H29ClFN7O2Purity:98%Color and Shape:SolidMolecular weight:513.99Compound 1T-0219 (SC)
CAS:Compound 1T-0219 (SC) is a blocker of AKT1-FAK interaction reducing the stimulation of FAK phosphorylation in response to extracellular pressure in human SW620Formula:C20H19N3O7Purity:90%Color and Shape:SolidMolecular weight:413.38ALK inhibitor 2
CAS:ALK inhibitor 2 is a new-type and selective inhibitor for the ALK kinase.Formula:C23H28ClN7O3SPurity:99% - 99.77%Color and Shape:SolidMolecular weight:518.03(R)-Fangchinoline
CAS:(R)-Fangchinoline ((+)-Thalrugosine) is extracted from Stephania tetrandra S. Moore.Formula:C37H40N2O6Purity:98% - 99.72%Color and Shape:SolidMolecular weight:608.72
