p53
p53 inhibitors target the p53 protein, a tumor suppressor that plays a crucial role in regulating the cell cycle, DNA repair, and apoptosis. While p53 is often mutated or inactivated in cancer cells, its inhibition is sometimes necessary to protect healthy cells from apoptosis during certain treatments. On the other hand, restoring p53 function in tumors can lead to cancer cell apoptosis. Research into p53 inhibitors is complex and significant for both understanding cancer mechanisms and developing new therapies. At CymitQuimica, we provide a selection of high-quality p53 inhibitors and modulators to support your research in cancer biology, apoptosis, and therapeutic development.
Products of "p53"
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UNC0646
CAS:UNC0646 is a potent and selective inhibitor of the homologous protein lysine methyltransferases, G9a and GLP with low cellular toxicity.Formula:C36H59N7O2Purity:100%Color and Shape:SolidMolecular weight:621.9UNC 0631
CAS:UNC 0631 is a effectvie histone methyltransferase G9a inhibitor (IC50=4 nM).Formula:C37H61N7O2Purity:98.76%Color and Shape:SolidMolecular weight:635.93NSC-87877 disodium
CAS:NSC-87877 disodium (NSC87877) is a cell-permeable inhibitor of both SHP-1 and SHP-2. NSC-87877 also inhibits EGF-induced Erk1/2 activation in HEK293 cells.Formula:C19H13N3O7S2·2NaPurity:97.89%Color and Shape:SolidMolecular weight:503.42HLA-A*02:01&B2M&P53 R175H (HMTEVVRHC) Tetramer Protein, Human, MHC (His & Avi)
p53 is a tumor suppressor protein.Color and Shape:Odour Lyophilized PowderAmifostine trihydrate
CAS:Amifostine trihydrate (WR2721) is the first approved radioprotective drug, used to decrease the risk of kidney problems caused by treatment with cisplatin.Formula:C5H15N2O3PS·3H2OPurity:99.71% - 99.80%Color and Shape:SolidMolecular weight:268.27Anti-p53 Antibody (9D896)
Anti-p53 Antibody (9D896) is an antibody targeting p53. Anti-p53 Antibody (9D896) can be used in ELISA, WB, IHC, IF.Color and Shape:Odour LiquidDPBQ
CAS:DPBQ (ZINC1620467) is a p53 activator.Formula:C24H14N2O2Purity:98.73%Color and Shape:SolidMolecular weight:362.38Ref: TM-T11092
1mg105.00€2mg158.00€5mg259.00€10mg374.00€25mg562.00€50mg775.00€100mg1,035.00€500mgTo inquireAnti-p53 Antibody (2V863)
Anti-p53 Antibody (2V863) is a Mouse antibody targeting p53. Anti-p53 Antibody (2V863) can be used in ELISA,ELISA(Det).Color and Shape:Odour LiquidNSC348884
CAS:NSC348884, a nucleophosmin inhibitor, disrupts oligomers, induces apoptosis, and inhibits cancer cell growth (IC50: 1.7-4.0 μM).Formula:C38H40N10Purity:98.69% - 99.91%Color and Shape:SolidMolecular weight:636.79Ref: TM-T6909
2mg42.00€5mg62.00€10mg96.00€25mg180.00€50mg296.00€100mg427.00€500mg938.00€1mL*10mM (DMSO)85.00€Benzonitrile, 3,3'-[(2-oxo-1,3-cyclohexanediylidene)dimethylidyne]bis-
CAS:Benzonitrile, 3,3'-[(2-oxo-1,3-cyclohexanediylidene)dimethylidyne]bis- (9CI) is an inhibitor of p53 with an IC50 value of 0.35 μMFormula:C22H16N2OPurity:99.18%Color and Shape:SolidMolecular weight:324.38Ref: TM-T9129
1mg52.00€5mg107.00€10mg158.00€25mg259.00€50mg374.00€100mg523.00€200mg710.00€1mL*10mM (DMSO)111.00€cjoc42
CAS:Cjoc42 blocks gankyrin to prevent p53 reduction, aiding cancer prevention and DNA damage response.Formula:C20H21N3O5SPurity:98.54%Color and Shape:SolidMolecular weight:415.46Ref: TM-T27029
1mg64.00€5mg140.00€10mg205.00€25mg368.00€50mg552.00€100mg770.00€200mg1,035.00€1mL*10mM (DMSO)160.00€Proteasome inhibitor IX
CAS:Proteasome inhibitor IX (PS-IX) is an inhibitor of chymotrypsin-like activity of the 20S proteasome (IC50 ~1 μM).Formula:C20H21B2NO5Purity:98.7%Color and Shape:SolidMolecular weight:377.01KCC-07
CAS:KCC-07: Selective, potent, brain-penetrant MBD2 inhibitor with anticancer effects, blocking MBD2-DNA binding and activating BAI1 signaling.Formula:C14H11N3OSPurity:98.86% - 99.01%Color and Shape:SolidMolecular weight:269.32Ref: TM-T8554
1mg40.00€2mg52.00€5mg79.00€10mg124.00€25mg235.00€50mg374.00€100mg555.00€500mg1,206.00€1mL*10mM (DMSO)82.00€Tetrofosmin
CAS:Tetrofosmin is a phosphine developed to overcome the non-target uptake of radioligands by the generation of hetero-atomic compounds.Formula:C18H40O4P2Color and Shape:SolidMolecular weight:382.46Quinacrine dihydrochloride
CAS:Quinacrine dihydrochloride (Mepacrine dihydrochloride) is the dihydrochloride salt of the 9-aminoacridine derivative quinacrine with potential antineoplasticFormula:C23H30CLN3O·2HClPurity:98.24% - 99.72%Color and Shape:Yellow Crystals Or PowderMolecular weight:472.88Lumichrome
CAS:Lumichrome, a riboflavin metabolite, influences plant growth, ascidian metamorphosis, bacterial communication, and blocks riboflavin uptake.Formula:C12H10N4O2Purity:99.65% - 99.69%Color and Shape:SolidMolecular weight:242.23P53R3
CAS:P53R3 is a potent reactivator of p53, effectively restoring sequence-specific DNA binding to several p53 hot spot mutants, namely p53 R175H, p53 R248W, and p53Formula:C32H35Cl2N5O2Purity:97.75%Color and Shape:SolidMolecular weight:592.56Unesbulin
CAS:Unesbulin (PTC596) is an orally active and selective inhibitor of B-cell-specific Moloney murine leukemia virus integration site 1 (BMI-1).Formula:C19H13F5N6Purity:98.71%Color and Shape:SolidMolecular weight:420.34YK-3-237
CAS:YK-3-237 (B-[2-Methoxy-5-[(1E)-3-oxo-3-(3,4,5-trimethoxyphenyl)-1-propen-1-yl]phenyl]boronic acid) reduces acetylation of mtp53 and exhibits anti-proliferativeFormula:C19H21BO7Purity:99.47%Color and Shape:SolidMolecular weight:372.18Ref: TM-T9320
2mg40.00€5mg60.00€10mg87.00€25mg180.00€50mg305.00€100mg535.00€200mg690.00€500mg1,074.00€1mL*10mM (DMSO)66.00€XI-006
CAS:NSC-207895 (XI-006) suppresses MDMX with IC50 of 2.5 μM, leading to enhanced p53 stabilization/activation and DNA damage, and regulates MDM2, an E3 ligase.Formula:C11H13N5O4Purity:99.12%Color and Shape:SolidMolecular weight:279.25Ref: TM-T6610
1mg56.00€2mg81.00€5mg119.00€10mg187.00€25mg432.00€50mg638.00€100mg908.00€500mg1,825.00€1mL*10mM (DMSO)114.00€
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